Pancoast Tumor

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R Lisbona - One of the best experts on this subject based on the ideXlab platform.

Joseph S. Mclaughlin - One of the best experts on this subject based on the ideXlab platform.

  • Superior sulcus (Pancoast) Tumor: experience with 105 patients
    The Annals of thoracic surgery, 1998
    Co-Authors: Safuh Attar, Mark J. Krasna, Joshua R. Sonett, John R. Hankins, Robert G. Slawson, Charles M. Suter, Joseph S. Mclaughlin
    Abstract:

    Abstract Background . The evolution of therapy in 105 patients with superior sulcus (Pancoast) Tumor over the past 42 years was reviewed. Methods . There were 82 men and 23 women aged 30 to 75 years. Tumor cell types were: squamous, 41 (39%); adenocarcinoma, 23 (21.9%); anaplastic, 14 (13.3%); undetermined, 12 (11.4%); mixed, 9 (8.7%); and large cell 6 (5.7%). Therapy was based on extent of disease and lymph node involvement. There were 5 treatment groups: I, preoperative radiation and operation (n = 28); II, operation and postoperative radiation (n = 16); III, radiation (n = 37); IV, preoperative chemotherapy, radiation, and operation (n = 11); and V, operation (n = 12). Results . The median survival for group I was 21.6 months; group II, 6.9 months; group III, 6 months; and group V, 36.7 months. Median survival for group IV has not yet been reached (estimated at 72% at 5 years). On univariate analysis, mediastinal lymph node involvement, Horner syndrome, TNM classification, and method of therapy affected survival. On multivariate regression analysis, only N2 and N3 disease and method of therapy were significant ( p Conclusions . The optimal treatment for superior sulcus Tumor was preoperative radiation and operation. However, triple modality therapy, although promising, requires longer follow-up.

  • subarachnoid pleural fistula after resection of a Pancoast Tumor with hyponatremia
    The Annals of Thoracic Surgery, 1995
    Co-Authors: Paul Boyev, Mark J. Krasna, Charles S White, Joseph S. Mclaughlin
    Abstract:

    Resection of superior sulcus neoplasms is associated with a number of complications resulting from the extensive nature of the resection and the necessity to sacrifice certain adjacent structures. One of the complications of resection is the development of subarachnoid-pleural fistula, with the subsequent appearance of air in the cerebrospinal fluid circulation. We report a case in which a subarachnoid-pleural fistula led to persistent pneumocephaly in a patient who exhibited postoperative hyponatremia, confusion, and gait disturbance.

Vilma Derbekyan - One of the best experts on this subject based on the ideXlab platform.

Paul Zarogoulidis - One of the best experts on this subject based on the ideXlab platform.

  • Diagnosing and treating Pancoast Tumors
    Expert review of respiratory medicine, 2016
    Co-Authors: Konstantinos Zarogoulidis, Konstantinos Porpodis, Kelly Domvri, Ellada Eleftheriadou, Despoina Ioannidou, Paul Zarogoulidis
    Abstract:

    ABSTRACTIntroduction: According to the American College of Chest Physician definition, a Pancoast Tumor is a Tumor which invades any of the structures of the apex of the chest including the first thoracic ribs or periosteum, the lower nerve roots of the bronchial plexus, the sympathetic chain and stellate gaglion near the apex of the chest or the subclavian vessels. Pancoast Tumors account for less than 3–5 % of lung Tumors.Areas covered: We searched the libraries scopus and pub med and found 124 related manuscripts. From those we chose 18 to include in our short commentary based on the most up-date information included.Expert commentary: The present status of the recommended treatment of Pancoast Tumors for patients medically fit for surgical resection is trimodality (chemoradiation followed by radical surgery excersion) as state of the art. Patients with unresectable Pancoast Tumors and poor PS 4 or distant metastasis are candidate for radiation therapy for palliation of symptoms and best supportive car...

Ralph A. Schmid - One of the best experts on this subject based on the ideXlab platform.

  • Tuberculosis presenting as Pancoast Tumor.
    The Annals of thoracic surgery, 2003
    Co-Authors: Morris Beshay, Thierry Roth, Robert Stein, Ralph A. Schmid
    Abstract:

    A 48-year-old man presented with pain in his left shoulder radiating to the left scapula and a tingling sensation of the left arm with involvement of the fourth and fifth finger. Based on the clinical and radiologic findings, the diagnosis of Pancoast Tumor of the left lung was made. Computed tomographic guided fine needle biopsy was not conclusive. A video-assisted thoracoscopic surgery was performed to obtain a biopsy. The histologic and microbiologic examinations established the diagnosis of tuberculosis (TB).