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F. Ferro - One of the best experts on this subject based on the ideXlab platform.
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epididymal testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely Patent Processus Vaginalis
Journal of Anatomy, 2014Co-Authors: S. Caterino, L. Lorenzon, M. Cavallini, D. Cavaniglia, F. FerroAbstract:Past studies documented the presence of epididymal/testicular fusion anomalies and persistence of a Patent Processus Vaginalis in a small case-series of cryptorchid and/or hydrocele patients. The primary aim of this study was to determine the prevalence of the epididymal/testicular anomalies in a series of more than 1000 cryptorchid patients compared with controls. Secondary aims were: (i) to investigate the association between the cryptorchidism and the patency of p. Vaginalis; and (ii) to correlate the epididymal/testicular fusion anomalies with the position of the testis and with the patency of the p. Vaginalis. The clinical and surgical data of 1002 cryptorchid patients and 230 controls were retrospectively retrieved and analysed. Epididymal/testicular fusion anomalies were classified as: (i) normal anatomy; (ii) minor anomalies; and (iii) major anomalies. Statistical analysis was performed using the Student's t-test and Chi-square tests. The prevalence of the epididymal/testicular fusion anomalies was higher in the cryptorchid group compared with that of the control group (minor and major anomalies in cryptorchids vs. controls, respectively: 42.2 vs. 5.6% and 9.3 vs. 1.6%, P < 0.0001). Moreover, we documented a correlation of these anomalies with a more proximal localization of the testis (minor and major anomalies in proximal vs. distal location of the testis, respectively: 62.5 vs. 34.8% and 19.1 vs. 6.3%, P < 0.0001) and with the persistence of a widely Patent p. Vaginalis (minor and major anomalies in widely Patent p. Vaginalis vs. narrow duct, respectively: 51.7 vs. 42.2 and 11.9% vs. 7.8%, P < 0.001). In conclusion, the epididymal/testicular fusion anomalies were strongly associated with cryptorchidism and the persistence of a widely Patent peritoneal vaginal duct. Although it remains unclear whether these anomalies cause non-descent of the testis or, conversely, result from the cryptorchidism or from the persistence of a widely Patent duct, our data re-enforce this association.
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Epididymal-testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely Patent Processus Vaginalis.
'Wiley', 2014Co-Authors: S. Caterino, L. Lorenzon, M. Cavallini, D. Cavaniglia, F. FerroAbstract:Past studies documented the presence of epididymal/testicular fusion anomalies and persistence of a Patent Processus Vaginalis in a small case-series of cryptorchid and/or hydrocele patients. The primary aim of this study was to determine the prevalence of the epididymal/testicular anomalies in a series of more than 1000 cryptorchid patients compared with controls. Secondary aims were: (i) to investigate the association between the cryptorchidism and the patency of p. Vaginalis; and (ii) to correlate the epididymal/testicular fusion anomalies with the position of the testis and with the patency of the p. Vaginalis. The clinical and surgical data of 1002 cryptorchid patients and 230 controls were retrospectively retrieved and analysed. Epididymal/testicular fusion anomalies were classified as: (i) normal anatomy; (ii) minor anomalies; and (iii) major anomalies. Statistical analysis was performed using the Student's t-test and Chi-square tests. The prevalence of the epididymal/testicular fusion anomalies was higher in the cryptorchid group compared with that of the control group (minor and major anomalies in cryptorchids vs. controls, respectively: 42.2 vs. 5.6\% and 9.3 vs. 1.6\%, P
S. Caterino - One of the best experts on this subject based on the ideXlab platform.
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epididymal testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely Patent Processus Vaginalis
Journal of Anatomy, 2014Co-Authors: S. Caterino, L. Lorenzon, M. Cavallini, D. Cavaniglia, F. FerroAbstract:Past studies documented the presence of epididymal/testicular fusion anomalies and persistence of a Patent Processus Vaginalis in a small case-series of cryptorchid and/or hydrocele patients. The primary aim of this study was to determine the prevalence of the epididymal/testicular anomalies in a series of more than 1000 cryptorchid patients compared with controls. Secondary aims were: (i) to investigate the association between the cryptorchidism and the patency of p. Vaginalis; and (ii) to correlate the epididymal/testicular fusion anomalies with the position of the testis and with the patency of the p. Vaginalis. The clinical and surgical data of 1002 cryptorchid patients and 230 controls were retrospectively retrieved and analysed. Epididymal/testicular fusion anomalies were classified as: (i) normal anatomy; (ii) minor anomalies; and (iii) major anomalies. Statistical analysis was performed using the Student's t-test and Chi-square tests. The prevalence of the epididymal/testicular fusion anomalies was higher in the cryptorchid group compared with that of the control group (minor and major anomalies in cryptorchids vs. controls, respectively: 42.2 vs. 5.6% and 9.3 vs. 1.6%, P < 0.0001). Moreover, we documented a correlation of these anomalies with a more proximal localization of the testis (minor and major anomalies in proximal vs. distal location of the testis, respectively: 62.5 vs. 34.8% and 19.1 vs. 6.3%, P < 0.0001) and with the persistence of a widely Patent p. Vaginalis (minor and major anomalies in widely Patent p. Vaginalis vs. narrow duct, respectively: 51.7 vs. 42.2 and 11.9% vs. 7.8%, P < 0.001). In conclusion, the epididymal/testicular fusion anomalies were strongly associated with cryptorchidism and the persistence of a widely Patent peritoneal vaginal duct. Although it remains unclear whether these anomalies cause non-descent of the testis or, conversely, result from the cryptorchidism or from the persistence of a widely Patent duct, our data re-enforce this association.
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Epididymal-testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely Patent Processus Vaginalis.
'Wiley', 2014Co-Authors: S. Caterino, L. Lorenzon, M. Cavallini, D. Cavaniglia, F. FerroAbstract:Past studies documented the presence of epididymal/testicular fusion anomalies and persistence of a Patent Processus Vaginalis in a small case-series of cryptorchid and/or hydrocele patients. The primary aim of this study was to determine the prevalence of the epididymal/testicular anomalies in a series of more than 1000 cryptorchid patients compared with controls. Secondary aims were: (i) to investigate the association between the cryptorchidism and the patency of p. Vaginalis; and (ii) to correlate the epididymal/testicular fusion anomalies with the position of the testis and with the patency of the p. Vaginalis. The clinical and surgical data of 1002 cryptorchid patients and 230 controls were retrospectively retrieved and analysed. Epididymal/testicular fusion anomalies were classified as: (i) normal anatomy; (ii) minor anomalies; and (iii) major anomalies. Statistical analysis was performed using the Student's t-test and Chi-square tests. The prevalence of the epididymal/testicular fusion anomalies was higher in the cryptorchid group compared with that of the control group (minor and major anomalies in cryptorchids vs. controls, respectively: 42.2 vs. 5.6\% and 9.3 vs. 1.6\%, P
David P. Meagher - One of the best experts on this subject based on the ideXlab platform.
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Laparoscopic evaluation of contralateral Patent Processus Vaginalis in children
American journal of surgery, 1996Co-Authors: Katharina Pellegrin, Denis D. Bensard, Frederick M. Karrer, David P. MeagherAbstract:Background Routine contralateral inguinal exploration following unilateral herniorrhaphy in children remains controversial. Contralateral Patent Processus Vaginalis (PPV) incidence decreases from 80% in young infants to about 20% to 30% in the adult population. However, the incidence of a clinical hernia appearing subsequently following unilateral herniorrhaphy is 6% to 10%. Methods Fifty consecutive children were evaluated by diagnostic laparoscopy (DL) at the time of inguinal herniorrhaphy. Results The mean age was 3 years. Thirteen of 42 patients (31 %) with a symptomatic confirmed hernia had a contralateral PPV by DL. The mean operating time was 48 minutes. The sensitivity was 98% with a specificity of 100%. No child suffered a complication due to DL. Conclusions We found diagnostic laparoscopy in children with evidence of unilateral inguinal hernia (1) was safe, (2) revealed a 31% incidence of contralateral PPV, and (3) eliminated the need for contralateral exploration in 69%.
K. J. P. Van Wessem - One of the best experts on this subject based on the ideXlab platform.
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Patent Processus Vaginalis in the adult as a risk factor for the occurrence of indirect inguinal hernia
Surgical endoscopy, 2006Co-Authors: R. N. Van Veen, K. J. P. Van Wessem, J.a. Halm, Maarten Simons, P. W. Plaisier, Johannes Jeekel, Janusz LangeAbstract:Background Inguinal hernias are a common entity with nearly 31,000 repairs annually in The Netherlands and over 800,000 in the USA. The aim of the present study is to determine whether a laparoscopically diagnosed Patent Processus Vaginalis (PPV) is a risk factor for the development of groin hernia. Methods The study population was originally composed of 599 consecutive cases (189 male, 32%) of laparoscopic transperitoneal surgery for different indications performed in 4 teaching hospitals in The Netherlands between November 1998 and February 2002. During laparoscopy, the deep inguinal ring was inspected bilaterally. The PPV group was compared with the obliterative Processus Vaginalis (OPV) group. Results After a mean follow-up of 5.5 years, the studied population consisted of 337 cases (94 male, 28%). In this study 12% of the studied population appeared to have PPV in adult life. The percentage PPV of our study group is much higher than the percentage of hernia repairs performed in the Dutch population. A greater proportion (12%) of hernia repairs in the PPV group was found as compared with the OPV group (3%). The chance of developing an inguinal hernia within 5.3 years is four times higher in the group with PPV. No significant correlation between age and the prevalence of PPV was observed. Conclusion This study demonstrates that PPV is an etiologic factor and a risk factor for acquiring an indirect inguinal hernia in adults.
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the etiology of indirect inguinal hernias congenital and or acquired
Hernia, 2003Co-Authors: K. J. P. Van Wessem, P. W. Plaisier, M P Simons, J F LangeAbstract:The development of indirect inguinal hernias in infants is caused by a Patent Processus Vaginalis (PPV). Consequently, this type of hernia is cured by simple herniotomy. In adults, however, herniotomy alone is accompanied by a high recurrence rate. This indicates that additional factors play a part in the development of indirect inguinal hernias in adults. The aim of this study was to determine the etiology of the development of an indirect hernia in adult life. Also, the prevalence of a PPV without clinical evidence of a hernia was determined and related to age. From November 1998 until February 2002, 599 patients from four different teaching hospitals, who underwent abdominal laparoscopy for various pathologies, were included. During laparoscopy, the deep inguinal ring was bilaterally inspected. Patients undergoing laparoscopy for inguinal hernia repair were excluded. Mean age was 45 years (range 8–89 years). Thirty-two percent (189/599) were male. Twelve percent (71/599) had PPV, all without clinical symptoms. Fifty-five percent (39/71) with PPV were male (P<0.0001). Fifty-nine percent (42/71) with PPV were right-sided, 29% (21/71) with PPV were left sided, and 12% (8/71) were bilateral (P=0.01). The prevalence of PPV in patients under 20 years was 22%. Of those between 20 and 30 years of age, 6% had PPV. Of those between 30 and 50 years, 24 patients (11%) had PPV. Of patients over 50 years, 33 (14%) had PPV. No significant differences between ages were observed. It is concluded that asymptomatic Patent Processus Vaginalis frequently exists in adult life. The prevalence of PPV does not increase significantly with age. Assuming that indirect hernias start with asymptomatic peritoneal protrusion that can be observed laparoscopically, the incidence of PPV, like the incidence of adult indirect hernias, should increase in case of acquired etiology. Such an increase of incidence with age was not confirmed by our results. It is concluded that the etiology of indirect inguinal hernia in adults, as in infants, is congenital.
L. Lorenzon - One of the best experts on this subject based on the ideXlab platform.
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epididymal testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely Patent Processus Vaginalis
Journal of Anatomy, 2014Co-Authors: S. Caterino, L. Lorenzon, M. Cavallini, D. Cavaniglia, F. FerroAbstract:Past studies documented the presence of epididymal/testicular fusion anomalies and persistence of a Patent Processus Vaginalis in a small case-series of cryptorchid and/or hydrocele patients. The primary aim of this study was to determine the prevalence of the epididymal/testicular anomalies in a series of more than 1000 cryptorchid patients compared with controls. Secondary aims were: (i) to investigate the association between the cryptorchidism and the patency of p. Vaginalis; and (ii) to correlate the epididymal/testicular fusion anomalies with the position of the testis and with the patency of the p. Vaginalis. The clinical and surgical data of 1002 cryptorchid patients and 230 controls were retrospectively retrieved and analysed. Epididymal/testicular fusion anomalies were classified as: (i) normal anatomy; (ii) minor anomalies; and (iii) major anomalies. Statistical analysis was performed using the Student's t-test and Chi-square tests. The prevalence of the epididymal/testicular fusion anomalies was higher in the cryptorchid group compared with that of the control group (minor and major anomalies in cryptorchids vs. controls, respectively: 42.2 vs. 5.6% and 9.3 vs. 1.6%, P < 0.0001). Moreover, we documented a correlation of these anomalies with a more proximal localization of the testis (minor and major anomalies in proximal vs. distal location of the testis, respectively: 62.5 vs. 34.8% and 19.1 vs. 6.3%, P < 0.0001) and with the persistence of a widely Patent p. Vaginalis (minor and major anomalies in widely Patent p. Vaginalis vs. narrow duct, respectively: 51.7 vs. 42.2 and 11.9% vs. 7.8%, P < 0.001). In conclusion, the epididymal/testicular fusion anomalies were strongly associated with cryptorchidism and the persistence of a widely Patent peritoneal vaginal duct. Although it remains unclear whether these anomalies cause non-descent of the testis or, conversely, result from the cryptorchidism or from the persistence of a widely Patent duct, our data re-enforce this association.
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Epididymal-testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely Patent Processus Vaginalis.
'Wiley', 2014Co-Authors: S. Caterino, L. Lorenzon, M. Cavallini, D. Cavaniglia, F. FerroAbstract:Past studies documented the presence of epididymal/testicular fusion anomalies and persistence of a Patent Processus Vaginalis in a small case-series of cryptorchid and/or hydrocele patients. The primary aim of this study was to determine the prevalence of the epididymal/testicular anomalies in a series of more than 1000 cryptorchid patients compared with controls. Secondary aims were: (i) to investigate the association between the cryptorchidism and the patency of p. Vaginalis; and (ii) to correlate the epididymal/testicular fusion anomalies with the position of the testis and with the patency of the p. Vaginalis. The clinical and surgical data of 1002 cryptorchid patients and 230 controls were retrospectively retrieved and analysed. Epididymal/testicular fusion anomalies were classified as: (i) normal anatomy; (ii) minor anomalies; and (iii) major anomalies. Statistical analysis was performed using the Student's t-test and Chi-square tests. The prevalence of the epididymal/testicular fusion anomalies was higher in the cryptorchid group compared with that of the control group (minor and major anomalies in cryptorchids vs. controls, respectively: 42.2 vs. 5.6\% and 9.3 vs. 1.6\%, P