The Experts below are selected from a list of 2073 Experts worldwide ranked by ideXlab platform
Didier Raoult - One of the best experts on this subject based on the ideXlab platform.
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assessment of oral ivermectin versus shampoo in the treatment of Pediculosis head lice infestation in rural areas of sine saloum senegal
International Journal of Antimicrobial Agents, 2016Co-Authors: Hamza Leulmi, Cheikh Sokhna, Jean-marc Rolain, Georges Diatta, Didier RaoultAbstract:Reports of treatment failure and the emergence of resistance to topical head lice treatments have become increasingly common, driving the need for continued development of new therapeutic options for Pediculosis. Ivermectin has been proposed as a potential alternative for the treatment of Pediculosis but has not been sufficiently evaluated. In this study, the effectiveness of oral ivermectin versus shampoo in the treatment of Pediculosis in Senegal was compared. The study was conducted in two neighbouring villages of Sine-Saloum, Senegal: Dielmo (ivermectin trial group; 201 female participants) and Ndiop (shampoo trial group; 239 female participants). In the ivermectin group, patients received two doses of oral ivermectin (400 µg/kg body weight; Mectizan®) 7 days apart. In contrast, the shampoo group received a shampoo treatment based on d-phenothrin (0.23%; Hegor®). At the beginning of the study, 70 (34.8%) of 201 participants in the ivermectin group were infested by head lice versus 145 (60.7%) of 239 participants in the shampoo group. At Day 15 post-treatment, the efficacy of the treatment against head lice reached 41/53 (77.4%) in the ivermectin group (53 patients were tested in this group) versus 42/130 (32.3%) in the shampoo group (130 patients were tested in this group) (P <10-7). However, 4 (7.5%) of the 53 females in the ivermectin group exhibited probable ivermectin treatment failure, suggesting the emergence of ivermectin-resistant lice. This study demonstrates that oral ivermectin is highly effective for the treatment of Pediculosis compared with shampoo, but also suggests that ivermectin resistance may emerge during treatment.
E Zangvil - One of the best experts on this subject based on the ideXlab platform.
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seasonality trends of Pediculosis capitis and phthirus pubis in a young adult population follow up of 20 years
Journal of The European Academy of Dermatology and Venereology, 2002Co-Authors: Daniel Mimouni, Omer E Ankol, Nadav Davidovitch, Michael Gdalevich, Itamar Grotto, E ZangvilAbstract:Background It is not mandatory to report Pediculosis capitis and Phthirus pubis in most countries; therefore, little is known about the seasonality of these infestations. Methods We analysed the data based on routine and mandatory reporting of every case of Pediculosis capitis and Phthirus pubis to the Army Health Branch Epidemiology Department, Israel, over the last two decades. Results The average 20-year incidence of Pediculosis capitis shows a significant rise during the warmer months (R2 = 0.692, P < 0.05) with a parallel significant decrease in the cooler months (R2 = 0.893, P < 0.05). The results for Phthirus pubis show a significantly higher person-time incidence in the winter (P < 0.001). Sensitivity analysis to investigate possible sources of heterogeneity during this time indicated that no single year was an important source of heterogeneity. ConclusionsPediculosis capitis is more frequent in the warmer months, whereas Phthirus pubis is more dominant in the cooler months.
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Seasonality trends of Pediculosis capitis and Phthirus pubis in a young adult population: follow-up of 20 years
Journal of The European Academy of Dermatology and Venereology, 2002Co-Authors: Daniel Mimouni, Omer E Ankol, Nadav Davidovitch, Michael Gdalevich, Itamar Grotto, E ZangvilAbstract:Background It is not mandatory to report Pediculosis capitis and Phthirus pubis in most countries; therefore, little is known about the seasonality of these infestations. Methods We analysed the data based on routine and mandatory reporting of every case of Pediculosis capitis and Phthirus pubis to the Army Health Branch Epidemiology Department, Israel, over the last two decades. Results The average 20-year incidence of Pediculosis capitis shows a significant rise during the warmer months (R2 = 0.692, P
Peter D Massey - One of the best experts on this subject based on the ideXlab platform.
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A systematic literature review of Pediculosis due to head lice in the Pacific Island Countries and Territories: what country specific research on head lice is needed?
BMC Dermatology, 2014Co-Authors: Rick Speare, Humpress Harrington, Deon Canyon, Peter D MasseyAbstract:Background Lack of guidelines on control of Pediculosis in the Solomon Islands led to a search for relevant evidence on head lice in the Pacific Island Countries and Territories (PICTs). The aim of this search was to systematically evaluate evidence in the peer reviewed literature on Pediculosis due to head lice ( Pediculus humanus var capitis ) in the 22 PICTs from the perspective of its value in informing national guidelines and control strategies. Methods PubMed, Web of Science, CINAHL and Scopus were searched using the terms (Pediculosis OR head lice) AND each of the 22 PICTs individually. PRISMA methodology was used. Exclusion criteria were: i) not on topic; ii) publications on Pediculosis not relevant to the country of the particular search; iii) in grey literature. Results Of 24 publications identified, only 5 were included. Four related to treatment and one to epidemiology. None contained information relevant to informing national guidelines. Conclusions Current local evidence on head lice in the PICTs is minimal and totally inadequate to guide any recommendations for treatment or control. We recommend that local research is required to generate evidence on: i) epidemiology; ii) knowledge, attitudes and practices of health care providers and community members; iii) efficacy of local commercially available pharmaceutical treatments and local customary treatments; iv) acceptability, accessibility and affordability of available treatment strategies; and iv) appropriate control strategies for families, groups and institutions. We also recommend that operational research be done by local researchers based in the PICTs, supported by experienced head lice researchers, using a two way research capacity building model.
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a systematic literature review of Pediculosis due to head lice in the pacific island countries and territories what country specific research on head lice is needed
BMC Dermatology, 2014Co-Authors: Rick Speare, Humpress Harrington, Deon Canyon, Peter D MasseyAbstract:Background Lack of guidelines on control of Pediculosis in the Solomon Islands led to a search for relevant evidence on head lice in the Pacific Island Countries and Territories (PICTs). The aim of this search was to systematically evaluate evidence in the peer reviewed literature on Pediculosis due to head lice (Pediculus humanus var capitis) in the 22 PICTs from the perspective of its value in informing national guidelines and control strategies.
Jean-marc Rolain - One of the best experts on this subject based on the ideXlab platform.
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assessment of oral ivermectin versus shampoo in the treatment of Pediculosis head lice infestation in rural areas of sine saloum senegal
International Journal of Antimicrobial Agents, 2016Co-Authors: Hamza Leulmi, Cheikh Sokhna, Jean-marc Rolain, Georges Diatta, Didier RaoultAbstract:Reports of treatment failure and the emergence of resistance to topical head lice treatments have become increasingly common, driving the need for continued development of new therapeutic options for Pediculosis. Ivermectin has been proposed as a potential alternative for the treatment of Pediculosis but has not been sufficiently evaluated. In this study, the effectiveness of oral ivermectin versus shampoo in the treatment of Pediculosis in Senegal was compared. The study was conducted in two neighbouring villages of Sine-Saloum, Senegal: Dielmo (ivermectin trial group; 201 female participants) and Ndiop (shampoo trial group; 239 female participants). In the ivermectin group, patients received two doses of oral ivermectin (400 µg/kg body weight; Mectizan®) 7 days apart. In contrast, the shampoo group received a shampoo treatment based on d-phenothrin (0.23%; Hegor®). At the beginning of the study, 70 (34.8%) of 201 participants in the ivermectin group were infested by head lice versus 145 (60.7%) of 239 participants in the shampoo group. At Day 15 post-treatment, the efficacy of the treatment against head lice reached 41/53 (77.4%) in the ivermectin group (53 patients were tested in this group) versus 42/130 (32.3%) in the shampoo group (130 patients were tested in this group) (P <10-7). However, 4 (7.5%) of the 53 females in the ivermectin group exhibited probable ivermectin treatment failure, suggesting the emergence of ivermectin-resistant lice. This study demonstrates that oral ivermectin is highly effective for the treatment of Pediculosis compared with shampoo, but also suggests that ivermectin resistance may emerge during treatment.
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Assessment of oral ivermectin versus shampoo in the treatment of Pediculosis (head lice infestation) in rural areas of Sine-Saloum, Senegal
International Journal of Antimicrobial Agents, 2016Co-Authors: Hamza Leulmi, Cheikh Sokhna, Georges Diatta, Jean-marc RolainAbstract:Reports of treatment failure and the emergence of resistance to topical head lice treatments have become increasingly common, driving the need for continued development of new therapeutic options for Pediculosis. Ivermectin has been proposed as a potential alternative for the treatment of Pediculosis but has not been sufficiently evaluated. In this study, the effectiveness of oral ivermectin versus shampoo in the treatment of Pediculosis in Senegal was compared. The study was conducted in two neighbouring villages of Sine-Saloum, Senegal: Dielmo (ivermectin trial group; 201 female participants) and Ndiop (shampoo trial group; 239 female participants). In the ivermectin group, patients received two doses of oral ivermectin (400 mu g/kg body weight; Mectizan (R)) 7 days apart. In contrast, the shampoo group received a shampoo treatment based on D-phenothrin (0.23%; Hegor (R)). At the beginning of the study, 70 (34.8%) of 201 participants in the ivermectin group were infested by head lice versus 145 (60.7%) of 239 participants in the shampoo group. At Day 15 post-treatment, the efficacy of the treatment against head lice reached 41/53 (77.4%) in the ivermectin group (53 patients were tested in this group) versus 42/130 (32.3%) in the shampoo group (130 patients were tested in this group) (P < 10(-7)). However, 4 (7.5%) of the 53 females in the ivermectin group exhibited probable ivermectin treatment failure, suggesting the emergence of ivermectin-resistant lice. This study demonstrates that oral ivermectin is highly effective for the treatment of Pediculosis compared with shampoo, but also suggests that ivermectin resistance may emerge during treatment. (C) 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
Anne Rompalo - One of the best experts on this subject based on the ideXlab platform.
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scabies and Pediculosis pubis an update of treatment regimens and general review
Clinical Infectious Diseases, 2002Co-Authors: Karen A Wendel, Anne RompaloAbstract:The ectoparasites scabies and Pediculosis pubis are common causes of skin rash and pruritus worldwide. They are transmitted primarily by person-to-person spread and are generally associated with low morbidity. The preferred treatment for scabies has generally been topical agents such as lindane and permethrin. Recently, ivermectin has demonstrated good efficacy in the treatment of scabies, and it may be of particular use in institutional outbreaks and in communities in which scabies is endemic. Combination treatment with topical agents and oral ivermectin may be necessary for crusted scabies. Treatment of Pediculosis pubis is best accomplished with topical permethrin, lindane, or pyrethrins with piperonyl butoxide. Although resistance to these topical agents has been reported in head lice, decreased efficacy in the treatment of Pediculosis pubis has not been reported.