The Experts below are selected from a list of 267 Experts worldwide ranked by ideXlab platform
Awe - One of the best experts on this subject based on the ideXlab platform.
-
Reproductive and histological effects of garlic, antioxidant vitamins C and E on Pefloxacininduced toxicity in wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The reproductive effect of Pefloxacin (PF) and antioxidant vitamins C, E and garlic in wistar rats were evaluated. Fifty adult Albino wistar rats (120-180), of either sex were randomly selected into five study groups. Fifty rats were cohabited in matting ratio of 1:1 to give 5 study groups of 5 matting pairs per group. Reproductive parameters assessed were litter size, weight of offspring, morphological, organ weights. Control group was given placebo 0.5ml of normal saline while group II (Pefloxacin 11.43mg/kg body weight), group III same dose of Pefloxacin with 14.29mg/kg body weight of vitamin C supplement, group IV same dose of Pefloxacin with 14.29mg/kg body weight of vitamin E supplement and group V Pefloxacin with 4.28mg/kg body weight of garlic supplement in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. There was decrease in number of births (litter size) from 10 in the control to 2 in the PF treated and the PF treated and antioxidant supplemented group had higher litter size (8, 10 and 6) compared to PF treated only. Mean weight of off springs were significantly (P
-
Pefloxacin and antioxidant interactions of vitamins C, E and garlic, on serum enzymes and histological tissues in Albino wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The hepatic and some serum enzymes activity of garlic, antioxidant vitamins C and E on Pefloxacin-induced toxicity in wistar rat were evaluated. Method: One hundred adult wistar rats (120-180), of either sex were randomly selected into five study groups. Each group comprised of 10 pairs (ten males and ten females) were not allowed to mate, with group 1 as control. Group 11 were Pefloxacin treated only while group 111 to 1V were Pefloxacin treated with either garlic, vitamins C and E. Pefloxacin, garlic vitamin C and E in doses 11.43mg/kg, 4.28mg/kg, 14.29mg/kg body weight in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. Control animals received 0.5ml of normal saline. In life observation measurements were taken and at the end of drug, garlic, antioxidant vitamins C and E combined administration animals were sacrificed and tissues obtained for biochemical assessment. The effect of Pefloxacin only, Pefloxacin in diet with antioxidant vitamins C, E and garlic supplements respectively on the activity of serum enzyme aspartate aminotransaminase, alanine aminotransaminase, alkaline phosphotase, acid phosphotase, prostatic acid phosphotase, Pefloxacin administration induced a significant (P
Ukpanukpong - One of the best experts on this subject based on the ideXlab platform.
-
Reproductive and histological effects of garlic, antioxidant vitamins C and E on Pefloxacininduced toxicity in wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The reproductive effect of Pefloxacin (PF) and antioxidant vitamins C, E and garlic in wistar rats were evaluated. Fifty adult Albino wistar rats (120-180), of either sex were randomly selected into five study groups. Fifty rats were cohabited in matting ratio of 1:1 to give 5 study groups of 5 matting pairs per group. Reproductive parameters assessed were litter size, weight of offspring, morphological, organ weights. Control group was given placebo 0.5ml of normal saline while group II (Pefloxacin 11.43mg/kg body weight), group III same dose of Pefloxacin with 14.29mg/kg body weight of vitamin C supplement, group IV same dose of Pefloxacin with 14.29mg/kg body weight of vitamin E supplement and group V Pefloxacin with 4.28mg/kg body weight of garlic supplement in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. There was decrease in number of births (litter size) from 10 in the control to 2 in the PF treated and the PF treated and antioxidant supplemented group had higher litter size (8, 10 and 6) compared to PF treated only. Mean weight of off springs were significantly (P
-
Pefloxacin and antioxidant interactions of vitamins C, E and garlic, on serum enzymes and histological tissues in Albino wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The hepatic and some serum enzymes activity of garlic, antioxidant vitamins C and E on Pefloxacin-induced toxicity in wistar rat were evaluated. Method: One hundred adult wistar rats (120-180), of either sex were randomly selected into five study groups. Each group comprised of 10 pairs (ten males and ten females) were not allowed to mate, with group 1 as control. Group 11 were Pefloxacin treated only while group 111 to 1V were Pefloxacin treated with either garlic, vitamins C and E. Pefloxacin, garlic vitamin C and E in doses 11.43mg/kg, 4.28mg/kg, 14.29mg/kg body weight in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. Control animals received 0.5ml of normal saline. In life observation measurements were taken and at the end of drug, garlic, antioxidant vitamins C and E combined administration animals were sacrificed and tissues obtained for biochemical assessment. The effect of Pefloxacin only, Pefloxacin in diet with antioxidant vitamins C, E and garlic supplements respectively on the activity of serum enzyme aspartate aminotransaminase, alanine aminotransaminase, alkaline phosphotase, acid phosphotase, prostatic acid phosphotase, Pefloxacin administration induced a significant (P
Dasofunjo - One of the best experts on this subject based on the ideXlab platform.
-
Reproductive and histological effects of garlic, antioxidant vitamins C and E on Pefloxacininduced toxicity in wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The reproductive effect of Pefloxacin (PF) and antioxidant vitamins C, E and garlic in wistar rats were evaluated. Fifty adult Albino wistar rats (120-180), of either sex were randomly selected into five study groups. Fifty rats were cohabited in matting ratio of 1:1 to give 5 study groups of 5 matting pairs per group. Reproductive parameters assessed were litter size, weight of offspring, morphological, organ weights. Control group was given placebo 0.5ml of normal saline while group II (Pefloxacin 11.43mg/kg body weight), group III same dose of Pefloxacin with 14.29mg/kg body weight of vitamin C supplement, group IV same dose of Pefloxacin with 14.29mg/kg body weight of vitamin E supplement and group V Pefloxacin with 4.28mg/kg body weight of garlic supplement in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. There was decrease in number of births (litter size) from 10 in the control to 2 in the PF treated and the PF treated and antioxidant supplemented group had higher litter size (8, 10 and 6) compared to PF treated only. Mean weight of off springs were significantly (P
-
Pefloxacin and antioxidant interactions of vitamins C, E and garlic, on serum enzymes and histological tissues in Albino wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The hepatic and some serum enzymes activity of garlic, antioxidant vitamins C and E on Pefloxacin-induced toxicity in wistar rat were evaluated. Method: One hundred adult wistar rats (120-180), of either sex were randomly selected into five study groups. Each group comprised of 10 pairs (ten males and ten females) were not allowed to mate, with group 1 as control. Group 11 were Pefloxacin treated only while group 111 to 1V were Pefloxacin treated with either garlic, vitamins C and E. Pefloxacin, garlic vitamin C and E in doses 11.43mg/kg, 4.28mg/kg, 14.29mg/kg body weight in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. Control animals received 0.5ml of normal saline. In life observation measurements were taken and at the end of drug, garlic, antioxidant vitamins C and E combined administration animals were sacrificed and tissues obtained for biochemical assessment. The effect of Pefloxacin only, Pefloxacin in diet with antioxidant vitamins C, E and garlic supplements respectively on the activity of serum enzyme aspartate aminotransaminase, alanine aminotransaminase, alkaline phosphotase, acid phosphotase, prostatic acid phosphotase, Pefloxacin administration induced a significant (P
Pekene - One of the best experts on this subject based on the ideXlab platform.
-
Reproductive and histological effects of garlic, antioxidant vitamins C and E on Pefloxacininduced toxicity in wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The reproductive effect of Pefloxacin (PF) and antioxidant vitamins C, E and garlic in wistar rats were evaluated. Fifty adult Albino wistar rats (120-180), of either sex were randomly selected into five study groups. Fifty rats were cohabited in matting ratio of 1:1 to give 5 study groups of 5 matting pairs per group. Reproductive parameters assessed were litter size, weight of offspring, morphological, organ weights. Control group was given placebo 0.5ml of normal saline while group II (Pefloxacin 11.43mg/kg body weight), group III same dose of Pefloxacin with 14.29mg/kg body weight of vitamin C supplement, group IV same dose of Pefloxacin with 14.29mg/kg body weight of vitamin E supplement and group V Pefloxacin with 4.28mg/kg body weight of garlic supplement in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. There was decrease in number of births (litter size) from 10 in the control to 2 in the PF treated and the PF treated and antioxidant supplemented group had higher litter size (8, 10 and 6) compared to PF treated only. Mean weight of off springs were significantly (P
-
Pefloxacin and antioxidant interactions of vitamins C, E and garlic, on serum enzymes and histological tissues in Albino wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The hepatic and some serum enzymes activity of garlic, antioxidant vitamins C and E on Pefloxacin-induced toxicity in wistar rat were evaluated. Method: One hundred adult wistar rats (120-180), of either sex were randomly selected into five study groups. Each group comprised of 10 pairs (ten males and ten females) were not allowed to mate, with group 1 as control. Group 11 were Pefloxacin treated only while group 111 to 1V were Pefloxacin treated with either garlic, vitamins C and E. Pefloxacin, garlic vitamin C and E in doses 11.43mg/kg, 4.28mg/kg, 14.29mg/kg body weight in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. Control animals received 0.5ml of normal saline. In life observation measurements were taken and at the end of drug, garlic, antioxidant vitamins C and E combined administration animals were sacrificed and tissues obtained for biochemical assessment. The effect of Pefloxacin only, Pefloxacin in diet with antioxidant vitamins C, E and garlic supplements respectively on the activity of serum enzyme aspartate aminotransaminase, alanine aminotransaminase, alkaline phosphotase, acid phosphotase, prostatic acid phosphotase, Pefloxacin administration induced a significant (P
Abong - One of the best experts on this subject based on the ideXlab platform.
-
Reproductive and histological effects of garlic, antioxidant vitamins C and E on Pefloxacininduced toxicity in wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The reproductive effect of Pefloxacin (PF) and antioxidant vitamins C, E and garlic in wistar rats were evaluated. Fifty adult Albino wistar rats (120-180), of either sex were randomly selected into five study groups. Fifty rats were cohabited in matting ratio of 1:1 to give 5 study groups of 5 matting pairs per group. Reproductive parameters assessed were litter size, weight of offspring, morphological, organ weights. Control group was given placebo 0.5ml of normal saline while group II (Pefloxacin 11.43mg/kg body weight), group III same dose of Pefloxacin with 14.29mg/kg body weight of vitamin C supplement, group IV same dose of Pefloxacin with 14.29mg/kg body weight of vitamin E supplement and group V Pefloxacin with 4.28mg/kg body weight of garlic supplement in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. There was decrease in number of births (litter size) from 10 in the control to 2 in the PF treated and the PF treated and antioxidant supplemented group had higher litter size (8, 10 and 6) compared to PF treated only. Mean weight of off springs were significantly (P
-
Pefloxacin and antioxidant interactions of vitamins C, E and garlic, on serum enzymes and histological tissues in Albino wistar rats
European Journal of Experimental Biology, 2013Co-Authors: Ukpanukpong, Dasofunjo, Pekene, Abong, Ugwu, AweAbstract:The hepatic and some serum enzymes activity of garlic, antioxidant vitamins C and E on Pefloxacin-induced toxicity in wistar rat were evaluated. Method: One hundred adult wistar rats (120-180), of either sex were randomly selected into five study groups. Each group comprised of 10 pairs (ten males and ten females) were not allowed to mate, with group 1 as control. Group 11 were Pefloxacin treated only while group 111 to 1V were Pefloxacin treated with either garlic, vitamins C and E. Pefloxacin, garlic vitamin C and E in doses 11.43mg/kg, 4.28mg/kg, 14.29mg/kg body weight in normal saline (vehicle) was administered orally by intubation to both male and female of groups 11 to V for 14 days. Control animals received 0.5ml of normal saline. In life observation measurements were taken and at the end of drug, garlic, antioxidant vitamins C and E combined administration animals were sacrificed and tissues obtained for biochemical assessment. The effect of Pefloxacin only, Pefloxacin in diet with antioxidant vitamins C, E and garlic supplements respectively on the activity of serum enzyme aspartate aminotransaminase, alanine aminotransaminase, alkaline phosphotase, acid phosphotase, prostatic acid phosphotase, Pefloxacin administration induced a significant (P