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E. Aagaard Nohr - One of the best experts on this subject based on the ideXlab platform.
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Age at menarche and pregnancy-related Pelvic Pain.
Journal of Obstetrics and Gynaecology Research, 2013Co-Authors: Mette J. Kirkeby, Karin Biering, Jørn Olsen, Mette Juhl, E. Aagaard NohrAbstract:Aim Menarcheal age is a predictor of several complications related to pregnancy and diseases later in life. We aimed to study if menarcheal age is a risk factor for pregnancy-related Pelvic Pain. Material and Methods A nested case–control study was conducted within the Danish National Birth Cohort, a cohort of pregnant women, recruited during 1996–2002, and their children. In the second trimester of pregnancy the women provided information about age at menarche and potential confounders. Selection of cases (n = 2227) was based on self-reported Pelvic Pain during pregnancy from an interview done 6 months post-partum. The controls (n = 2588) were randomly selected among women who did not report Pelvic Pain. We used logistic regression analysis to calculate odds ratios (OR) for pregnancy-related Pelvic Pain according to age at menarche. Results In the cohort, 18.5% of all pregnant women reported pregnancy-related Pelvic Pain. Compared to women who were 12–14 years old at menarche, the adjusted OR for overall Pelvic Pain were 1.4 (95% confidence interval [CI] 1.1–1.7) in women 11 years or younger and 0.8 (95%CI 0.6–0.9) in women 15 years or older. The corresponding adjusted OR for severe Pelvic Pain were 1.6 (95%CI 1.3–2.0) and 0.7 (95%CI 0.6–0.9). When age was analyzed as a continuous variable, the odds for overall and severe Pelvic Pain decreased with 14% and 16%, respectively, for each increasing year. Conclusions The risk of pregnancy-related Pelvic Pain decreased with increasing menarcheal age in an ‘exposure-response’ pattern. A low menarcheal age is a risk indicator and may be a risk factor for pregnancy-related Pelvic Pain.
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Smoking and pregnancy-related Pelvic Pain.
British Journal of Obstetrics and Gynaecology, 2010Co-Authors: Karin Biering, E. Aagaard Nohr, Jørn Olsen, Niels Henrik Hjollund, A-m Nybo Andersen, Mette JuhlAbstract:Please cite this paper as: Biering K, Aagaard Nohr E, Olsen J, Hjollund N, Nybo Andersen A-M, Juhl M. Smoking and pregnancy-related Pelvic Pain. BJOG 2010;117:1019–1026. Objective To investigate possible associations between smoking and pregnancy-related Pelvic Pain. Design Nested case–control study. Setting Denmark 2000–2001. Population The Danish National Birth Cohort. Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported Pelvic Pain, and controls were selected among women who did not report Pelvic Pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and Pelvic Pain. Main outcome mreasue Pregnancy-related Pelvic Pain. Results Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0–1.4) for overall Pelvic Pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1–1.7). The equivalent adjusted odds ratio for severe Pelvic Pain was 1.2 (1.0–1.5) for smokers, and 1.5 (1.2–1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with Pelvic Pain in a dose–response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results. Conclusions Smoking was associated with pregnancy-related Pelvic Pain, with a dose–response pattern between reported smoking intensity and Pelvic Pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.
Mette Juhl - One of the best experts on this subject based on the ideXlab platform.
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Age at menarche and pregnancy-related Pelvic Pain.
Journal of Obstetrics and Gynaecology Research, 2013Co-Authors: Mette J. Kirkeby, Karin Biering, Jørn Olsen, Mette Juhl, E. Aagaard NohrAbstract:Aim Menarcheal age is a predictor of several complications related to pregnancy and diseases later in life. We aimed to study if menarcheal age is a risk factor for pregnancy-related Pelvic Pain. Material and Methods A nested case–control study was conducted within the Danish National Birth Cohort, a cohort of pregnant women, recruited during 1996–2002, and their children. In the second trimester of pregnancy the women provided information about age at menarche and potential confounders. Selection of cases (n = 2227) was based on self-reported Pelvic Pain during pregnancy from an interview done 6 months post-partum. The controls (n = 2588) were randomly selected among women who did not report Pelvic Pain. We used logistic regression analysis to calculate odds ratios (OR) for pregnancy-related Pelvic Pain according to age at menarche. Results In the cohort, 18.5% of all pregnant women reported pregnancy-related Pelvic Pain. Compared to women who were 12–14 years old at menarche, the adjusted OR for overall Pelvic Pain were 1.4 (95% confidence interval [CI] 1.1–1.7) in women 11 years or younger and 0.8 (95%CI 0.6–0.9) in women 15 years or older. The corresponding adjusted OR for severe Pelvic Pain were 1.6 (95%CI 1.3–2.0) and 0.7 (95%CI 0.6–0.9). When age was analyzed as a continuous variable, the odds for overall and severe Pelvic Pain decreased with 14% and 16%, respectively, for each increasing year. Conclusions The risk of pregnancy-related Pelvic Pain decreased with increasing menarcheal age in an ‘exposure-response’ pattern. A low menarcheal age is a risk indicator and may be a risk factor for pregnancy-related Pelvic Pain.
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Smoking and pregnancy-related Pelvic Pain.
British Journal of Obstetrics and Gynaecology, 2010Co-Authors: Karin Biering, E. Aagaard Nohr, Jørn Olsen, Niels Henrik Hjollund, A-m Nybo Andersen, Mette JuhlAbstract:Please cite this paper as: Biering K, Aagaard Nohr E, Olsen J, Hjollund N, Nybo Andersen A-M, Juhl M. Smoking and pregnancy-related Pelvic Pain. BJOG 2010;117:1019–1026. Objective To investigate possible associations between smoking and pregnancy-related Pelvic Pain. Design Nested case–control study. Setting Denmark 2000–2001. Population The Danish National Birth Cohort. Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported Pelvic Pain, and controls were selected among women who did not report Pelvic Pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and Pelvic Pain. Main outcome mreasue Pregnancy-related Pelvic Pain. Results Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0–1.4) for overall Pelvic Pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1–1.7). The equivalent adjusted odds ratio for severe Pelvic Pain was 1.2 (1.0–1.5) for smokers, and 1.5 (1.2–1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with Pelvic Pain in a dose–response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results. Conclusions Smoking was associated with pregnancy-related Pelvic Pain, with a dose–response pattern between reported smoking intensity and Pelvic Pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.
Fred M Howard - One of the best experts on this subject based on the ideXlab platform.
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endometriosis and mechanisms of Pelvic Pain
Journal of Minimally Invasive Gynecology, 2009Co-Authors: Fred M HowardAbstract:Endometriosis remains an enigmatic disorder in that the cause, the natural history, and the precise mechanisms by which it causes Pain are not completely understood. The Pain symptoms most commonly attributed to endometriosis are dysmenorrhea, dyspareunia, and chronic Pelvic Pain. Pain may be due to nociceptive, inflammatory, or neuropathic mechanisms, and there is evidence that all 3 of these mechanisms are relevant to endometriosis-associated Pelvic Pain. It is proposed that the clinically observed inconsistencies of the relationships of endometriosis severity and the presence or severity of Pain are likely due to variable roles of different Pain mechanisms in endometriosis. A better understanding of the roles of nociceptive, inflammatory, and neuropathic Pain in endometriosis is likely to improve the treatment of women with endometriosis-associated Pelvic Pain.
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chronic Pelvic Pain
Obstetrics & Gynecology, 2003Co-Authors: Fred M HowardAbstract:Chronic Pelvic Pain is a common and significant disorder of women. It is estimated to have a prevalence of 3.8% in women. Often the etiology of chronic Pelvic Pain is not clear, as there are many disorders of the reproductive tract, gastrointestinal system, urological organs, musculoskeletal system, and psychoneurological system that may be associated with chronic Pelvic Pain. The history and physical examination are crucial in evaluating a woman with chronic Pelvic Pain and must address all of the possible systems potentially involved in chronic Pelvic Pain, not just the reproductive system. Laboratory and imaging studies should be selectively utilized, as should laparoscopy. Conscious laparoscopic Pain mapping has been proposed as a way to improve information derived from laparoscopic evaluations. Treatment of chronic Pelvic Pain may consist of two approaches. One is to treat chronic Pain itself as a diagnosis, and the other is to treat diseases or disorders that might be a cause of or a contributor to chronic Pelvic Pain. These two approaches are not mutually exclusive, and in many patients effective therapy is best achieved by using both approaches. Treatment of chronic Pain as well as treatment of four of the more common disorders associated with chronic Pelvic Pain (endometriosis, adhesions, irritable bowel syndrome, and interstitial cystitis) are discussed in this review.
Karin Biering - One of the best experts on this subject based on the ideXlab platform.
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Age at menarche and pregnancy-related Pelvic Pain.
Journal of Obstetrics and Gynaecology Research, 2013Co-Authors: Mette J. Kirkeby, Karin Biering, Jørn Olsen, Mette Juhl, E. Aagaard NohrAbstract:Aim Menarcheal age is a predictor of several complications related to pregnancy and diseases later in life. We aimed to study if menarcheal age is a risk factor for pregnancy-related Pelvic Pain. Material and Methods A nested case–control study was conducted within the Danish National Birth Cohort, a cohort of pregnant women, recruited during 1996–2002, and their children. In the second trimester of pregnancy the women provided information about age at menarche and potential confounders. Selection of cases (n = 2227) was based on self-reported Pelvic Pain during pregnancy from an interview done 6 months post-partum. The controls (n = 2588) were randomly selected among women who did not report Pelvic Pain. We used logistic regression analysis to calculate odds ratios (OR) for pregnancy-related Pelvic Pain according to age at menarche. Results In the cohort, 18.5% of all pregnant women reported pregnancy-related Pelvic Pain. Compared to women who were 12–14 years old at menarche, the adjusted OR for overall Pelvic Pain were 1.4 (95% confidence interval [CI] 1.1–1.7) in women 11 years or younger and 0.8 (95%CI 0.6–0.9) in women 15 years or older. The corresponding adjusted OR for severe Pelvic Pain were 1.6 (95%CI 1.3–2.0) and 0.7 (95%CI 0.6–0.9). When age was analyzed as a continuous variable, the odds for overall and severe Pelvic Pain decreased with 14% and 16%, respectively, for each increasing year. Conclusions The risk of pregnancy-related Pelvic Pain decreased with increasing menarcheal age in an ‘exposure-response’ pattern. A low menarcheal age is a risk indicator and may be a risk factor for pregnancy-related Pelvic Pain.
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Smoking and pregnancy-related Pelvic Pain.
British Journal of Obstetrics and Gynaecology, 2010Co-Authors: Karin Biering, E. Aagaard Nohr, Jørn Olsen, Niels Henrik Hjollund, A-m Nybo Andersen, Mette JuhlAbstract:Please cite this paper as: Biering K, Aagaard Nohr E, Olsen J, Hjollund N, Nybo Andersen A-M, Juhl M. Smoking and pregnancy-related Pelvic Pain. BJOG 2010;117:1019–1026. Objective To investigate possible associations between smoking and pregnancy-related Pelvic Pain. Design Nested case–control study. Setting Denmark 2000–2001. Population The Danish National Birth Cohort. Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported Pelvic Pain, and controls were selected among women who did not report Pelvic Pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and Pelvic Pain. Main outcome mreasue Pregnancy-related Pelvic Pain. Results Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0–1.4) for overall Pelvic Pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1–1.7). The equivalent adjusted odds ratio for severe Pelvic Pain was 1.2 (1.0–1.5) for smokers, and 1.5 (1.2–1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with Pelvic Pain in a dose–response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results. Conclusions Smoking was associated with pregnancy-related Pelvic Pain, with a dose–response pattern between reported smoking intensity and Pelvic Pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.
Jørn Olsen - One of the best experts on this subject based on the ideXlab platform.
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Age at menarche and pregnancy-related Pelvic Pain.
Journal of Obstetrics and Gynaecology Research, 2013Co-Authors: Mette J. Kirkeby, Karin Biering, Jørn Olsen, Mette Juhl, E. Aagaard NohrAbstract:Aim Menarcheal age is a predictor of several complications related to pregnancy and diseases later in life. We aimed to study if menarcheal age is a risk factor for pregnancy-related Pelvic Pain. Material and Methods A nested case–control study was conducted within the Danish National Birth Cohort, a cohort of pregnant women, recruited during 1996–2002, and their children. In the second trimester of pregnancy the women provided information about age at menarche and potential confounders. Selection of cases (n = 2227) was based on self-reported Pelvic Pain during pregnancy from an interview done 6 months post-partum. The controls (n = 2588) were randomly selected among women who did not report Pelvic Pain. We used logistic regression analysis to calculate odds ratios (OR) for pregnancy-related Pelvic Pain according to age at menarche. Results In the cohort, 18.5% of all pregnant women reported pregnancy-related Pelvic Pain. Compared to women who were 12–14 years old at menarche, the adjusted OR for overall Pelvic Pain were 1.4 (95% confidence interval [CI] 1.1–1.7) in women 11 years or younger and 0.8 (95%CI 0.6–0.9) in women 15 years or older. The corresponding adjusted OR for severe Pelvic Pain were 1.6 (95%CI 1.3–2.0) and 0.7 (95%CI 0.6–0.9). When age was analyzed as a continuous variable, the odds for overall and severe Pelvic Pain decreased with 14% and 16%, respectively, for each increasing year. Conclusions The risk of pregnancy-related Pelvic Pain decreased with increasing menarcheal age in an ‘exposure-response’ pattern. A low menarcheal age is a risk indicator and may be a risk factor for pregnancy-related Pelvic Pain.
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Smoking and pregnancy-related Pelvic Pain.
British Journal of Obstetrics and Gynaecology, 2010Co-Authors: Karin Biering, E. Aagaard Nohr, Jørn Olsen, Niels Henrik Hjollund, A-m Nybo Andersen, Mette JuhlAbstract:Please cite this paper as: Biering K, Aagaard Nohr E, Olsen J, Hjollund N, Nybo Andersen A-M, Juhl M. Smoking and pregnancy-related Pelvic Pain. BJOG 2010;117:1019–1026. Objective To investigate possible associations between smoking and pregnancy-related Pelvic Pain. Design Nested case–control study. Setting Denmark 2000–2001. Population The Danish National Birth Cohort. Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported Pelvic Pain, and controls were selected among women who did not report Pelvic Pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and Pelvic Pain. Main outcome mreasue Pregnancy-related Pelvic Pain. Results Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0–1.4) for overall Pelvic Pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1–1.7). The equivalent adjusted odds ratio for severe Pelvic Pain was 1.2 (1.0–1.5) for smokers, and 1.5 (1.2–1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with Pelvic Pain in a dose–response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results. Conclusions Smoking was associated with pregnancy-related Pelvic Pain, with a dose–response pattern between reported smoking intensity and Pelvic Pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.
