The Experts below are selected from a list of 6285 Experts worldwide ranked by ideXlab platform
Tsunehiko Nishimura - One of the best experts on this subject based on the ideXlab platform.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra. Materials and methods Sixteen patients with nonlacunar ischemic stroke who were scanned within 24 h after onset of symptoms were selected for the study. In previous studies, the level of regional cerebral blood flow (rCBF) in the normal white matter of the contralateral hemisphere was defined as 22 ml/100 g/min. We used this level as a standard of reference. We hypothesized that rCBF below this level would be amenable to infarct. The lesion-to-white matter ratios of rCBF were measured in the regions of ischemic core (“Core”), infarcted penumbra (“Growth”), salvaged penumbra (“Reversed”), and contralateral normal cortex (“Normal”). Results The rCBF of “Growth” and “Reversed” areas showed substantial overlap, which hampered the delineation of areas that would become infarcted. Conclusion The semiquantitative rCBF derived from MR PWI may not accurately characterize the ischemic penumbra.
Jan Sobesky - One of the best experts on this subject based on the ideXlab platform.
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influence of the arterial input function on absolute and relative Perfusion Weighted Imaging penumbral flow detection a validation with 15o water positron emission tomography
Stroke, 2012Co-Authors: Olivier Zaroweber, Wolf-dieter Heiss, Walter Moellerhartmann, Jan SobeskyAbstract:Background and Purpose—Perfusion-Weighted Imaging maps are used to identify critical hypoPerfusion in acute stroke. However, quantification of Perfusion may depend on the choice of the arterial input function (AIF). Using quantitative positron emission tomography we evaluated the influence of the AIF location on maps of absolute and relative Perfusion-Weighted Imaging to detect penumbral flow (PF; <20 mL/100 g/min on positron emission tomographyCBF) in acute stroke. Methods—In 22 patients with acute stroke the AIF was placed at 7 sites (M1, M2, M3 ipsi- and contralateral and internal carotid artery–M1 contralateral to the infarct). Comparative 15O-water positron emission tomography and AIF-dependent Perfusion-Weighted Imaging (cerebral blood flow, cerebral blood volume, mean transit time, and time to maximum) were performed. A receiver operating characteristic curve analysis described the threshold independent performance (area under the curve) of the Perfusion-Weighted maps for all 7 AIF locations and id...
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Influence of the Arterial Input Function on Absolute and Relative Perfusion-Weighted Imaging Penumbral Flow Detection A Validation With 15O-Water Positron Emission Tomography
Stroke, 2011Co-Authors: Olivier Zaro-weber, Walter Moeller-hartmann, Wolf-dieter Heiss, Jan SobeskyAbstract:Background and Purpose—Perfusion-Weighted Imaging maps are used to identify critical hypoPerfusion in acute stroke. However, quantification of Perfusion may depend on the choice of the arterial input function (AIF). Using quantitative positron emission tomography we evaluated the influence of the AIF location on maps of absolute and relative Perfusion-Weighted Imaging to detect penumbral flow (PF;
Kentaro Akazawa - One of the best experts on this subject based on the ideXlab platform.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra. Materials and methods Sixteen patients with nonlacunar ischemic stroke who were scanned within 24 h after onset of symptoms were selected for the study. In previous studies, the level of regional cerebral blood flow (rCBF) in the normal white matter of the contralateral hemisphere was defined as 22 ml/100 g/min. We used this level as a standard of reference. We hypothesized that rCBF below this level would be amenable to infarct. The lesion-to-white matter ratios of rCBF were measured in the regions of ischemic core (“Core”), infarcted penumbra (“Growth”), salvaged penumbra (“Reversed”), and contralateral normal cortex (“Normal”). Results The rCBF of “Growth” and “Reversed” areas showed substantial overlap, which hampered the delineation of areas that would become infarcted. Conclusion The semiquantitative rCBF derived from MR PWI may not accurately characterize the ischemic penumbra.
Kei Yamada - One of the best experts on this subject based on the ideXlab platform.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra. Materials and methods Sixteen patients with nonlacunar ischemic stroke who were scanned within 24 h after onset of symptoms were selected for the study. In previous studies, the level of regional cerebral blood flow (rCBF) in the normal white matter of the contralateral hemisphere was defined as 22 ml/100 g/min. We used this level as a standard of reference. We hypothesized that rCBF below this level would be amenable to infarct. The lesion-to-white matter ratios of rCBF were measured in the regions of ischemic core (“Core”), infarcted penumbra (“Growth”), salvaged penumbra (“Reversed”), and contralateral normal cortex (“Normal”). Results The rCBF of “Growth” and “Reversed” areas showed substantial overlap, which hampered the delineation of areas that would become infarcted. Conclusion The semiquantitative rCBF derived from MR PWI may not accurately characterize the ischemic penumbra.
Masanori Nakagawa - One of the best experts on this subject based on the ideXlab platform.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra.
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Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR Perfusion-Weighted Imaging?
Neuroradiology, 2008Co-Authors: Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota, Yoshinari Nagakane, Nagato Kuriyama, Masanori Nakagawa, Tsunehiko NishimuraAbstract:Introduction The purpose of this study was to test if magnetic resonance (MR) Perfusion-Weighted Imaging (PWI) can reliably characterize the ischemic penumbra. Materials and methods Sixteen patients with nonlacunar ischemic stroke who were scanned within 24 h after onset of symptoms were selected for the study. In previous studies, the level of regional cerebral blood flow (rCBF) in the normal white matter of the contralateral hemisphere was defined as 22 ml/100 g/min. We used this level as a standard of reference. We hypothesized that rCBF below this level would be amenable to infarct. The lesion-to-white matter ratios of rCBF were measured in the regions of ischemic core (“Core”), infarcted penumbra (“Growth”), salvaged penumbra (“Reversed”), and contralateral normal cortex (“Normal”). Results The rCBF of “Growth” and “Reversed” areas showed substantial overlap, which hampered the delineation of areas that would become infarcted. Conclusion The semiquantitative rCBF derived from MR PWI may not accurately characterize the ischemic penumbra.