The Experts below are selected from a list of 19968 Experts worldwide ranked by ideXlab platform
Emilio Sastre - One of the best experts on this subject based on the ideXlab platform.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders: A Mainstream School-based Population Study in Central Spain.
Tremor and other hyperkinetic movements (New York N.Y.), 2014Co-Authors: Esther Cubo, Montes Hortigüela, Patricia Lopez, Leticia Velasco, Emilio Sastre, Sandra Jorge-roldan, Selva Esther Ciciliani, Vanesa Ausín, Vanesa Delgado, Sara SaezAbstract:Background: While current research suggests that genetic factors confer the greatest risk for the development of tic disorders, studies of environmental factors are relatively few, with a lack of consistent risk factors across studies. Our aim is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. Methods: This was a nested case–control study design. Cases and controls were selected and identified from a mainstream, school-based sample. The diagnosis of tic disorders was assigned by a movement disorder neurologist using ‘Diagnostic and statistical manual of mental disorders, 4th edition, text revision’ criteria, and neuropsychiatric comorbidities were screened using the Spanish computerized version of the Diagnostic Interview Schedule for Children Predictive Scale. Information regarding the exposure to pre-Perinatal risk factors was collected by a retrospective review of the birth certificates. Logistic regression analyses were then performed to test the association of tic disorders with pre-Perinatal risk factors. Results: Out of 407 participants, complete pre-Perinatal data were available in 153 children (64 with tics and 89 without tics). After adjusting for family history of tics, neonatal respiratory distress syndrome, body mass index, prenatal infection, and coexisting comorbid neuropsychiatric disturbances, tic disorders were associated with prenatal exposure to tobacco (odds ratio [OR]53.07, 95% confidence interval [CI] 1.24–7.60, p50.007), and cesarean section (OR55.78, 95% CI 1.60–20.91, p50.01). Discussion: This nested case–control study of children with tic disorders demonstrates higher adjusted odds for tics in children with exposure to cesarean delivery and maternal smoking. Longitudinal, population-based samples are required to confirm these results.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders. A Mainstream School-Based Population Study in Central Spain (P02.066)
Neurology, 2013Co-Authors: Esther Cubo, Montes Hortigüela, Sandra Roldan, Cecilia Ciciliani, Patricia Lopez, Leticia Velasco, Emilio SastreAbstract:OBJECTIVE: The objective of this study is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. BACKGROUND: Tic disorders are a childhood onset neurodevelopmental disorder. Whereas there is consistent literature documenting the association of prenatal and Perinatal Morbidity with attention deficit disorder (ADHD), little is known about this association with tic disorders. DESIGN/METHODS: Nested case-control design from a mainstream school-based sample in central Spain. Tic disorders and comorbid neuropsychiatric disorders were diagnosed based on DSM-IV TR criteria. Morbidity related to pregnancy, maternal disturbances, delivery, fetal distress, and Perinatal information was collected by medical chart retrospective review. Parametric tests were used for comparisons and logistic regression analysis to study the association of tics with exposure to pre-Perinatal Morbidity. RESULTS: From a sample of 1867 schoolchildren screened for tic disorders, 526 were assessed by the neurologist, and pre-Perinatal history was obtained in 226 children (154 males [68%], and 71 with tics [31%]). After adjusting for confounding variables including intelligence quotient, fetal distress, presence of ADHD, and maternal Morbidity, cesarean section (OR=6.2, p=0.001), family history of tics (OR=5.1, p=0.03), and maternal smoking (OR=3.1, p=0.03) were highly associated with tic disorders. CONCLUSIONS: Women with fetuses at risk for tic disorders should receive counseling to avoid smoking and cesarean section if possible, to minimize the odds of tic disorders. Supported by: SACYL, Biomedicine project GRS 157-A, Health Research Grant PI 070846, and the European General Development Co-funding. Disclosure: Dr. Cubo Delgado has received personal compensation for activities with Abbott and UCB Pharma. Dr. Hortiguela has nothing to disclose. Dr. Roldan has nothing to disclose. Dr. Ciciliani has nothing to disclose. Dr. Lopez has nothing to disclose. Dr. Velasco has nothing to disclose. Dr. Sastre has nothing to disclose.
Esther Cubo - One of the best experts on this subject based on the ideXlab platform.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders: A Mainstream School-based Population Study in Central Spain.
Tremor and other hyperkinetic movements (New York N.Y.), 2014Co-Authors: Esther Cubo, Montes Hortigüela, Patricia Lopez, Leticia Velasco, Emilio Sastre, Sandra Jorge-roldan, Selva Esther Ciciliani, Vanesa Ausín, Vanesa Delgado, Sara SaezAbstract:Background: While current research suggests that genetic factors confer the greatest risk for the development of tic disorders, studies of environmental factors are relatively few, with a lack of consistent risk factors across studies. Our aim is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. Methods: This was a nested case–control study design. Cases and controls were selected and identified from a mainstream, school-based sample. The diagnosis of tic disorders was assigned by a movement disorder neurologist using ‘Diagnostic and statistical manual of mental disorders, 4th edition, text revision’ criteria, and neuropsychiatric comorbidities were screened using the Spanish computerized version of the Diagnostic Interview Schedule for Children Predictive Scale. Information regarding the exposure to pre-Perinatal risk factors was collected by a retrospective review of the birth certificates. Logistic regression analyses were then performed to test the association of tic disorders with pre-Perinatal risk factors. Results: Out of 407 participants, complete pre-Perinatal data were available in 153 children (64 with tics and 89 without tics). After adjusting for family history of tics, neonatal respiratory distress syndrome, body mass index, prenatal infection, and coexisting comorbid neuropsychiatric disturbances, tic disorders were associated with prenatal exposure to tobacco (odds ratio [OR]53.07, 95% confidence interval [CI] 1.24–7.60, p50.007), and cesarean section (OR55.78, 95% CI 1.60–20.91, p50.01). Discussion: This nested case–control study of children with tic disorders demonstrates higher adjusted odds for tics in children with exposure to cesarean delivery and maternal smoking. Longitudinal, population-based samples are required to confirm these results.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders. A Mainstream School-Based Population Study in Central Spain (P02.066)
Neurology, 2013Co-Authors: Esther Cubo, Montes Hortigüela, Sandra Roldan, Cecilia Ciciliani, Patricia Lopez, Leticia Velasco, Emilio SastreAbstract:OBJECTIVE: The objective of this study is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. BACKGROUND: Tic disorders are a childhood onset neurodevelopmental disorder. Whereas there is consistent literature documenting the association of prenatal and Perinatal Morbidity with attention deficit disorder (ADHD), little is known about this association with tic disorders. DESIGN/METHODS: Nested case-control design from a mainstream school-based sample in central Spain. Tic disorders and comorbid neuropsychiatric disorders were diagnosed based on DSM-IV TR criteria. Morbidity related to pregnancy, maternal disturbances, delivery, fetal distress, and Perinatal information was collected by medical chart retrospective review. Parametric tests were used for comparisons and logistic regression analysis to study the association of tics with exposure to pre-Perinatal Morbidity. RESULTS: From a sample of 1867 schoolchildren screened for tic disorders, 526 were assessed by the neurologist, and pre-Perinatal history was obtained in 226 children (154 males [68%], and 71 with tics [31%]). After adjusting for confounding variables including intelligence quotient, fetal distress, presence of ADHD, and maternal Morbidity, cesarean section (OR=6.2, p=0.001), family history of tics (OR=5.1, p=0.03), and maternal smoking (OR=3.1, p=0.03) were highly associated with tic disorders. CONCLUSIONS: Women with fetuses at risk for tic disorders should receive counseling to avoid smoking and cesarean section if possible, to minimize the odds of tic disorders. Supported by: SACYL, Biomedicine project GRS 157-A, Health Research Grant PI 070846, and the European General Development Co-funding. Disclosure: Dr. Cubo Delgado has received personal compensation for activities with Abbott and UCB Pharma. Dr. Hortiguela has nothing to disclose. Dr. Roldan has nothing to disclose. Dr. Ciciliani has nothing to disclose. Dr. Lopez has nothing to disclose. Dr. Velasco has nothing to disclose. Dr. Sastre has nothing to disclose.
Xihui Cao - One of the best experts on this subject based on the ideXlab platform.
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high risk pregnancy associated Perinatal Morbidity and mortality a second birth population based survey in huai an in 2015
BMC Pregnancy and Childbirth, 2019Co-Authors: Xiaoqin Zhu, Huiyuan Niu, Hui Wang, Weijie Ding, Liangrong Han, Muling Zhang, Honghua Guan, Chunhong Tang, Yaodong Yin, Xihui CaoAbstract:The objective of this survey was to explore the association between pregnancy complications and Perinatal outcome from regionally total birth population. In this prospectively collected data of complete birth registries from all level I-III hospitals in Huai’an in 2015, Perinatal Morbidity and mortality in relation to pregnancy complications and Perinatal outcome were analyzed using international definitions. The results were compared with that of 2010 survey in the same region. Of 59,424 total births in the hospitals of level I (n = 85), II (16) and III (6), delivery rate was 30.4, 40.1 and 29.5%, and rates of pregnancy complications were 12.9, 9.8 and 21.1% (average 14.1%), with antenatal corticosteroids rate in < 37 gestational weeks being 17.3, 31.0 and 39.9% (mean 36.6%), respectively. The preterm birth rate was 0.6, 2.7 and 9.5% (mean 4.06%), and the composite rate of fetal death, stillbirth, and death immediately after delivery was 0.1, 0.4 and 0.6%, respectively. By multivariable logistic regression analysis, congenital anomalies, low Apgar scores, multi-pregnancy and amniotic fluid contamination were risk factors of adverse Perinatal outcomes. Despite a higher rate of pregnancy complications than in 2010 survey, Perinatal and neonatal mortality continued to fall, in particular in very preterm births. The high cesarean delivery rate in non-medically indicated cases remained a challenge. Our regional birth-population data in 2015 revealed a robust and persistent improvement in the Perinatal care and management of high risk pregnancies and deliveries, which should enable more studies using similar concept and protocol for vital statistics to verify the reliability and feasibility.
Sara Saez - One of the best experts on this subject based on the ideXlab platform.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders: A Mainstream School-based Population Study in Central Spain.
Tremor and other hyperkinetic movements (New York N.Y.), 2014Co-Authors: Esther Cubo, Montes Hortigüela, Patricia Lopez, Leticia Velasco, Emilio Sastre, Sandra Jorge-roldan, Selva Esther Ciciliani, Vanesa Ausín, Vanesa Delgado, Sara SaezAbstract:Background: While current research suggests that genetic factors confer the greatest risk for the development of tic disorders, studies of environmental factors are relatively few, with a lack of consistent risk factors across studies. Our aim is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. Methods: This was a nested case–control study design. Cases and controls were selected and identified from a mainstream, school-based sample. The diagnosis of tic disorders was assigned by a movement disorder neurologist using ‘Diagnostic and statistical manual of mental disorders, 4th edition, text revision’ criteria, and neuropsychiatric comorbidities were screened using the Spanish computerized version of the Diagnostic Interview Schedule for Children Predictive Scale. Information regarding the exposure to pre-Perinatal risk factors was collected by a retrospective review of the birth certificates. Logistic regression analyses were then performed to test the association of tic disorders with pre-Perinatal risk factors. Results: Out of 407 participants, complete pre-Perinatal data were available in 153 children (64 with tics and 89 without tics). After adjusting for family history of tics, neonatal respiratory distress syndrome, body mass index, prenatal infection, and coexisting comorbid neuropsychiatric disturbances, tic disorders were associated with prenatal exposure to tobacco (odds ratio [OR]53.07, 95% confidence interval [CI] 1.24–7.60, p50.007), and cesarean section (OR55.78, 95% CI 1.60–20.91, p50.01). Discussion: This nested case–control study of children with tic disorders demonstrates higher adjusted odds for tics in children with exposure to cesarean delivery and maternal smoking. Longitudinal, population-based samples are required to confirm these results.
Patricia Lopez - One of the best experts on this subject based on the ideXlab platform.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders: A Mainstream School-based Population Study in Central Spain.
Tremor and other hyperkinetic movements (New York N.Y.), 2014Co-Authors: Esther Cubo, Montes Hortigüela, Patricia Lopez, Leticia Velasco, Emilio Sastre, Sandra Jorge-roldan, Selva Esther Ciciliani, Vanesa Ausín, Vanesa Delgado, Sara SaezAbstract:Background: While current research suggests that genetic factors confer the greatest risk for the development of tic disorders, studies of environmental factors are relatively few, with a lack of consistent risk factors across studies. Our aim is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. Methods: This was a nested case–control study design. Cases and controls were selected and identified from a mainstream, school-based sample. The diagnosis of tic disorders was assigned by a movement disorder neurologist using ‘Diagnostic and statistical manual of mental disorders, 4th edition, text revision’ criteria, and neuropsychiatric comorbidities were screened using the Spanish computerized version of the Diagnostic Interview Schedule for Children Predictive Scale. Information regarding the exposure to pre-Perinatal risk factors was collected by a retrospective review of the birth certificates. Logistic regression analyses were then performed to test the association of tic disorders with pre-Perinatal risk factors. Results: Out of 407 participants, complete pre-Perinatal data were available in 153 children (64 with tics and 89 without tics). After adjusting for family history of tics, neonatal respiratory distress syndrome, body mass index, prenatal infection, and coexisting comorbid neuropsychiatric disturbances, tic disorders were associated with prenatal exposure to tobacco (odds ratio [OR]53.07, 95% confidence interval [CI] 1.24–7.60, p50.007), and cesarean section (OR55.78, 95% CI 1.60–20.91, p50.01). Discussion: This nested case–control study of children with tic disorders demonstrates higher adjusted odds for tics in children with exposure to cesarean delivery and maternal smoking. Longitudinal, population-based samples are required to confirm these results.
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Prenatal and Perinatal Morbidity in Children with Tic Disorders. A Mainstream School-Based Population Study in Central Spain (P02.066)
Neurology, 2013Co-Authors: Esther Cubo, Montes Hortigüela, Sandra Roldan, Cecilia Ciciliani, Patricia Lopez, Leticia Velasco, Emilio SastreAbstract:OBJECTIVE: The objective of this study is to analyze the association of tic disorders with exposure to prenatal and Perinatal Morbidity. BACKGROUND: Tic disorders are a childhood onset neurodevelopmental disorder. Whereas there is consistent literature documenting the association of prenatal and Perinatal Morbidity with attention deficit disorder (ADHD), little is known about this association with tic disorders. DESIGN/METHODS: Nested case-control design from a mainstream school-based sample in central Spain. Tic disorders and comorbid neuropsychiatric disorders were diagnosed based on DSM-IV TR criteria. Morbidity related to pregnancy, maternal disturbances, delivery, fetal distress, and Perinatal information was collected by medical chart retrospective review. Parametric tests were used for comparisons and logistic regression analysis to study the association of tics with exposure to pre-Perinatal Morbidity. RESULTS: From a sample of 1867 schoolchildren screened for tic disorders, 526 were assessed by the neurologist, and pre-Perinatal history was obtained in 226 children (154 males [68%], and 71 with tics [31%]). After adjusting for confounding variables including intelligence quotient, fetal distress, presence of ADHD, and maternal Morbidity, cesarean section (OR=6.2, p=0.001), family history of tics (OR=5.1, p=0.03), and maternal smoking (OR=3.1, p=0.03) were highly associated with tic disorders. CONCLUSIONS: Women with fetuses at risk for tic disorders should receive counseling to avoid smoking and cesarean section if possible, to minimize the odds of tic disorders. Supported by: SACYL, Biomedicine project GRS 157-A, Health Research Grant PI 070846, and the European General Development Co-funding. Disclosure: Dr. Cubo Delgado has received personal compensation for activities with Abbott and UCB Pharma. Dr. Hortiguela has nothing to disclose. Dr. Roldan has nothing to disclose. Dr. Ciciliani has nothing to disclose. Dr. Lopez has nothing to disclose. Dr. Velasco has nothing to disclose. Dr. Sastre has nothing to disclose.