The Experts below are selected from a list of 96 Experts worldwide ranked by ideXlab platform
Ganapati S Shankarling - One of the best experts on this subject based on the ideXlab platform.
-
environmentally benign and energy efficient methodology for condensation an interesting facet to the classical Perkin Reaction
Green Chemistry, 2011Co-Authors: Poonam Mahadev Pawar, Krishna J Jarag, Ganapati S ShankarlingAbstract:We have reported use of biodegradable deep eutectic solvent (DES) based on choline chloride and urea, for the synthesis of cinnamic acid and its derivatives viaPerkin Reaction. The Reaction proceeds efficiently under mild condition without use of additional catalyst with better yields. Ease of recovery and reusability of solvent with consistent activity makes this method efficient and environmentally benign. This method is also energy efficient and easy to handle.
John R Johnson - One of the best experts on this subject based on the ideXlab platform.
-
the Perkin Reaction and related Reactions
Organic Reactions, 2011Co-Authors: John R JohnsonAbstract:In 1868, W. H. Perkin described a synthesis of coumarin by heating the sodium salt of salicyaldehyde with acetic acid. Further study led to a new discovery for preparing cinnamic acid and its analogs by means of a synthesis of very general application, which became know as the Perkin Reaction. In the course of study of unsaturated acids, Fittig made several important contributions to the mechanism of the Perkin Reaction. Many studies have been made regarding this Reaction and are described. The Perkin Reaction may be regarded essential as the condensation of a carbonyl component A and an acid and dihydride-salt combination B. The discussion here is a survey of the types of carbonyl components and acid anhydride salt combinations that can be used and of the yields obtained under favorable conditions. Keywords: Perkin Reaction; carbonyl compounds; cinnamic acids; unsaturated acids; benzaldehyde; acid components; laboratory procedures; cinnamic acid derivatives; experimental conditions
Dmitri V Sevenard - One of the best experts on this subject based on the ideXlab platform.
-
3 polyfluoroalkyl substituted e cinnamic acids easy access via Perkin Reaction
Tetrahedron Letters, 2003Co-Authors: Dmitri V SevenardAbstract:Abstract 3-Polyfluoroalkyl-( E )-cinnamic acids being very useful building blocks were obtained by a simple and convenient one-step procedure. The Perkin type Reaction of fluoroacyl-substituted arenes gives the titled compounds in good yields and excellent stereoselectivity independent on the electronic nature of substituents in the aromatic ring. In the case of fluoroalkyl–alkylketones only O -acylation occures under the same conditions.
Poonam Mahadev Pawar - One of the best experts on this subject based on the ideXlab platform.
-
environmentally benign and energy efficient methodology for condensation an interesting facet to the classical Perkin Reaction
Green Chemistry, 2011Co-Authors: Poonam Mahadev Pawar, Krishna J Jarag, Ganapati S ShankarlingAbstract:We have reported use of biodegradable deep eutectic solvent (DES) based on choline chloride and urea, for the synthesis of cinnamic acid and its derivatives viaPerkin Reaction. The Reaction proceeds efficiently under mild condition without use of additional catalyst with better yields. Ease of recovery and reusability of solvent with consistent activity makes this method efficient and environmentally benign. This method is also energy efficient and easy to handle.
Krishna J Jarag - One of the best experts on this subject based on the ideXlab platform.
-
environmentally benign and energy efficient methodology for condensation an interesting facet to the classical Perkin Reaction
Green Chemistry, 2011Co-Authors: Poonam Mahadev Pawar, Krishna J Jarag, Ganapati S ShankarlingAbstract:We have reported use of biodegradable deep eutectic solvent (DES) based on choline chloride and urea, for the synthesis of cinnamic acid and its derivatives viaPerkin Reaction. The Reaction proceeds efficiently under mild condition without use of additional catalyst with better yields. Ease of recovery and reusability of solvent with consistent activity makes this method efficient and environmentally benign. This method is also energy efficient and easy to handle.