The Experts below are selected from a list of 849 Experts worldwide ranked by ideXlab platform
Elliot S. Barnathan - One of the best experts on this subject based on the ideXlab platform.
-
Chronic Facial Sarcoidosis Including Lupus Pernio
American Journal of Clinical Dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background : Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis. Objective : To evaluate the intra- and inter-observer consistency of objective measures of chronic facial lesions. Method : This was a retrospective study of patients with chronic cutaneous facial lesions including lupus Pernio. The lesions were evaluated using two methods. Results : Of the 25 patients studied, 23 were women and 24 were African American. Lungs (24 patients), sinuses (11 patients), and eyes (7 patients) were also affected. The Sarcoidosis Activity and Severity Index (SASI) characterized individual areas of the face, with 95% of the observations being less than 2 points from the median. A facial SASI total gave a score for the entire face and 93.2% of the scores were within 3 points of the median. Conclusion : Patients with sarcoidosis and chronic facial lesions often have lung, sinus, and eye involvement. The SASI is a reproducible scoring system for chronic facial lesions.
-
Chronic facial sarcoidosis including lupus Pernio: clinical description and proposed scoring systems.
American journal of clinical dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background: Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis.
Marc A. Judson - One of the best experts on this subject based on the ideXlab platform.
-
The Treatment of Lupus Pernio* Results of 116 Treatment Courses in 54 Patients
Chest, 2008Co-Authors: Eleni Stagaki, William K. Mountford, Daniel T. Lackland, Marc A. JudsonAbstract:Background Lupus Pernio is a disfiguring sarcoidosis skin lesion that is difficult to treat and often causes a major psychosocial impact that may adversely affect the patient's quality of life. We reviewed the treatment outcome of 54 patients with lupus Pernio who received 116 individual courses of treatment in our sarcoidosis clinic. Methods Lupus Pernio patients were identified from an institution-approved database. All patients were assessed at each clinic visit with facial photographs. By examining the photographs, the percentage of face involved ( 25 to 50%, > 50%) was determined as was the effect of therapy (resolution, near resolution, improvement, no change, worsening). Medications included infliximab-containing regimens; systemic corticosteroids; noninfliximab, noncorticosteroid agents; and corticosteroids plus noncorticosteroid agents. Results In terms of achieving resolution or near resolution, infliximab regimens were superior to all others (infliximab, 77%; corticosteroids plus noncorticosteroids, 29%; corticosteroids, 20%; noncorticosteroids, 11%; infliximab vs other therapies: corticosteroids plus noncorticosteroids, p = 0.0015; corticosteroids, p = 0.0005; noncorticosteroids, p = 0.0002). The percentage of facial involvement also improved most with infliximab. Evaluating a secondary analysis of achieving resolution, near resolution, or improvement, infliximab (92%) was superior to noncorticosteroids (20%; p Conclusions Infliximab appears superior to systemic corticosteroids with or without additional agents for the treatment of lupus Pernio. Noninfliximab, noncorticosteroid-containing regimens are of limited use for this condition.
-
Chronic Facial Sarcoidosis Including Lupus Pernio
American Journal of Clinical Dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background : Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis. Objective : To evaluate the intra- and inter-observer consistency of objective measures of chronic facial lesions. Method : This was a retrospective study of patients with chronic cutaneous facial lesions including lupus Pernio. The lesions were evaluated using two methods. Results : Of the 25 patients studied, 23 were women and 24 were African American. Lungs (24 patients), sinuses (11 patients), and eyes (7 patients) were also affected. The Sarcoidosis Activity and Severity Index (SASI) characterized individual areas of the face, with 95% of the observations being less than 2 points from the median. A facial SASI total gave a score for the entire face and 93.2% of the scores were within 3 points of the median. Conclusion : Patients with sarcoidosis and chronic facial lesions often have lung, sinus, and eye involvement. The SASI is a reproducible scoring system for chronic facial lesions.
-
Chronic facial sarcoidosis including lupus Pernio: clinical description and proposed scoring systems.
American journal of clinical dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background: Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis.
Kenneth S. Alpern - One of the best experts on this subject based on the ideXlab platform.
-
Treatment of lupus Pernio with the flashlamp pulsed dye laser
Lasers in surgery and medicine, 1992Co-Authors: Matthew M. Goodman, Kenneth S. AlpernAbstract:Lupus Pernio, a form of cutaneous sarcoidosis usually affecting the face, is often disfiguring and resistant to therapies, both medical and surgical. To our knowledge, there have been no previous reports of laser therapy for this condition. We describe a case of nasal lupus Pernio successfully managed with the flashlamp pulsed dye laser.
Robert P. Baughman - One of the best experts on this subject based on the ideXlab platform.
-
Chronic Facial Sarcoidosis Including Lupus Pernio
American Journal of Clinical Dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background : Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis. Objective : To evaluate the intra- and inter-observer consistency of objective measures of chronic facial lesions. Method : This was a retrospective study of patients with chronic cutaneous facial lesions including lupus Pernio. The lesions were evaluated using two methods. Results : Of the 25 patients studied, 23 were women and 24 were African American. Lungs (24 patients), sinuses (11 patients), and eyes (7 patients) were also affected. The Sarcoidosis Activity and Severity Index (SASI) characterized individual areas of the face, with 95% of the observations being less than 2 points from the median. A facial SASI total gave a score for the entire face and 93.2% of the scores were within 3 points of the median. Conclusion : Patients with sarcoidosis and chronic facial lesions often have lung, sinus, and eye involvement. The SASI is a reproducible scoring system for chronic facial lesions.
-
Chronic facial sarcoidosis including lupus Pernio: clinical description and proposed scoring systems.
American journal of clinical dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background: Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis.
Elyse E. Lower - One of the best experts on this subject based on the ideXlab platform.
-
Chronic Facial Sarcoidosis Including Lupus Pernio
American Journal of Clinical Dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background : Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis. Objective : To evaluate the intra- and inter-observer consistency of objective measures of chronic facial lesions. Method : This was a retrospective study of patients with chronic cutaneous facial lesions including lupus Pernio. The lesions were evaluated using two methods. Results : Of the 25 patients studied, 23 were women and 24 were African American. Lungs (24 patients), sinuses (11 patients), and eyes (7 patients) were also affected. The Sarcoidosis Activity and Severity Index (SASI) characterized individual areas of the face, with 95% of the observations being less than 2 points from the median. A facial SASI total gave a score for the entire face and 93.2% of the scores were within 3 points of the median. Conclusion : Patients with sarcoidosis and chronic facial lesions often have lung, sinus, and eye involvement. The SASI is a reproducible scoring system for chronic facial lesions.
-
Chronic facial sarcoidosis including lupus Pernio: clinical description and proposed scoring systems.
American journal of clinical dermatology, 2008Co-Authors: Robert P. Baughman, Marc A. Judson, Alvin Teirstein, Elyse E. Lower, Rozsa Schlenker-herceg, Elliot S. BarnathanAbstract:Background: Facial lesions including lupus Pernio are often a form of chronic cutaneous sarcoidosis.
-
Sleep apnea in sarcoidosis.
Sarcoidosis vasculitis and diffuse lung diseases : official journal of WASOG, 1997Co-Authors: G A Turner, Elyse E. Lower, B C Corser, K L Gunther, R. P. BaughmanAbstract:BACKGROUND AND AIM OF WORK Sleep apnea is reported to occur in 2-4% of the general population. Patients with sarcoidosis are at increased risk for sleep apnea, possibly due to factors such as steroid use, neurosarcoid, or upper airway obstruction. METHODS In order to determine the prevalence and risk factors for sleep apnea in sarcoidosis patients, we studied 83 consecutive patients with sarcoidosis seen over a six-week time period. Patients were screened using the Epworth Sleepiness Scale questionnaire and the age, sex, race, weight, and medications were recorded. The presence of previously diagnosed sleep apnea, neurosarcoid, lupus Pernio, and sinus disease were also noted. A control group of 91 patients seen in general pulmonary clinics were similarly screened. Patients with a positive sleep questionnaire were referred for sleep studies. RESULTS A total of 14 sarcoid patients (17%) were found to have sleep apnea, which was significantly higher than our control group with 3/91 (3%, p < 0.001). The presence of lupus Pernio was significantly more frequent in the sleep apnea group. Although 5/51 (10%) female sarcoid patients had sleep apnea, overall it was more frequent in male sarcoid patients. CONCLUSIONS Sleep apnea was frequent in sarcoid patients and was associated with lupus Pernio.