The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform
A Knippel - One of the best experts on this subject based on the ideXlab platform.
-
disseminated mycobacterium avium intracellulare infection in a Persian Cat
Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2004Co-Authors: A Knippel, U Hetzel, W BaumgartnerAbstract:Summary This report describes a disseminated infection with mycobacteria of the avium/intracellulare complex in a Persian Cat in the absence of cutaneous lesions. Postmortem examination revealed severe granulomatous inflammation with numerous intrahistiocytic acid-fast bacilli in multiple organs. A gastrointestinal port of entry seems likely, as the ileocaecal lymph node was most severely affected.
-
Disseminated Mycobacterium avium–intracellulare Infection in a Persian Cat
Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2004Co-Authors: A Knippel, U Hetzel, W BaumgartnerAbstract:Summary This report describes a disseminated infection with mycobacteria of the avium/intracellulare complex in a Persian Cat in the absence of cutaneous lesions. Postmortem examination revealed severe granulomatous inflammation with numerous intrahistiocytic acid-fast bacilli in multiple organs. A gastrointestinal port of entry seems likely, as the ileocaecal lymph node was most severely affected.
W Baumgartner - One of the best experts on this subject based on the ideXlab platform.
-
disseminated mycobacterium avium intracellulare infection in a Persian Cat
Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2004Co-Authors: A Knippel, U Hetzel, W BaumgartnerAbstract:Summary This report describes a disseminated infection with mycobacteria of the avium/intracellulare complex in a Persian Cat in the absence of cutaneous lesions. Postmortem examination revealed severe granulomatous inflammation with numerous intrahistiocytic acid-fast bacilli in multiple organs. A gastrointestinal port of entry seems likely, as the ileocaecal lymph node was most severely affected.
-
Disseminated Mycobacterium avium–intracellulare Infection in a Persian Cat
Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2004Co-Authors: A Knippel, U Hetzel, W BaumgartnerAbstract:Summary This report describes a disseminated infection with mycobacteria of the avium/intracellulare complex in a Persian Cat in the absence of cutaneous lesions. Postmortem examination revealed severe granulomatous inflammation with numerous intrahistiocytic acid-fast bacilli in multiple organs. A gastrointestinal port of entry seems likely, as the ileocaecal lymph node was most severely affected.
O Nilssen - One of the best experts on this subject based on the ideXlab platform.
-
PurifiCation of feline lysosomal alpha-mannosidase, determination of its cDNA sequence and identifiCation of a mutation causing alpha-mannosidosis in Persian Cats.
The Biochemical journal, 1997Co-Authors: T Berg, O K Tollersrud, S U Walkley, D Siegel, O NilssenAbstract:alpha-Mannosidosis is a lysosomal storage disorder that is caused by the deficiency of lysosomal alpha-mannosidase. Feline alpha-mannosidosis is a well-characterized animal model used for studying pathological and therapeutic aspects of lysosomal storage disorders. We here report the purifiCation of feline liver lysosomal alpha-mannosidase and determination of its cDNA sequence. The active enzyme consisted of three polypeptides, with molecular masses of 72, 41 and 12 kDa, joined by non-covalent forces. The cDNA sequence of feline lysosomal alpha-mannosidase was determined from reverse transcriptase PCR products obtained from skin fibroblast mRNA. The deduced amino acid sequence contained the N-terminal sequences of the 72 and 41 kDa peptides. This indiCated that the enzyme is synthesized as a single-chain precursor with a putative signal peptide of 50 amino acids followed by a polypeptide chain of 957 amino acids, which is cleaved into the three polypeptides of the mature enzyme. The deduced amino acid sequence was 81.1 and 83.2% identical with the human and bovine lysosomal alpha-mannosidases sequences respectively. A 4 bp deletion was identified in an alpha-mannosidosis-affected Persian Cat by DNA sequencing of reverse transcriptase PCR products. The deletion resulted in a frame shift from codon 583 and premature termination at codon 645. No lysosomal alpha-mannosidase activity could be detected in the liver of this Cat. A domestic long-haired Cat expressing a milder alpha-mannosidosis phenotype than the Persian Cat had a lysosomal alpha-mannosidase activity of 2% of normal. This domestic long-haired Cat did not possess the 4 bp deletion, proving molecular heterogeneity for feline alpha-mannosidosis.
-
PurifiCation of feline lysosomal α-mannosidase, determination of its cDNA sequence and identifiCation of a mutation causing α-mannosidosis in Persian Cats
Biochemical Journal, 1997Co-Authors: T Berg, K. Ole Tollersrud, U. Steven Walkley, Donald A. Siegel, O NilssenAbstract:α-Mannosidosis is a lysosomal storage disorder that is caused by the deficiency of lysosomal α-mannosidase. Feline α-mannosidosis is a well-characterized animal model used for studying pathological and therapeutic aspects of lysosomal storage disorders. We here report the purifiCation of feline liver lysosomal α-mannosidase and determination of its cDNA sequence. The active enzyme consisted of three polypeptides, with molecular masses of 72, 41 and 12 kDa, joined by non-covalent forces. The cDNA sequence of feline lysosomal α-mannosidase was determined from reverse transcriptase PCR products obtained from skin fibroblast mRNA. The deduced amino acid sequence contained the N-terminal sequences of the 72 and 41 kDa peptides. This indiCated that the enzyme is synthesized as a single-chain precursor with a putative signal peptide of 50 amino acids followed by a polypeptide chain of 957 amino acids, which is cleaved into the three polypeptides of the mature enzyme. The deduced amino acid sequence was 81.1 and 83.2% identical with the human and bovine lysosomal α-mannosidases sequences respectively. A 4 bp deletion was identified in an α-mannosidosis-affected Persian Cat by DNA sequencing of reverse transcriptase PCR products. The deletion resulted in a frame shift from codon 583 and premature termination at codon 645. No lysosomal α-mannosidase activity could be detected in the liver of this Cat. A domestic long-haired Cat expressing a milder α-mannosidosis phenotype than the Persian Cat had a lysosomal α-mannosidase activity of 2% of normal. This domestic long-haired Cat did not possess the 4 bp deletion, proving molecular heterogeneity for feline α-mannosidosis.
U Hetzel - One of the best experts on this subject based on the ideXlab platform.
-
disseminated mycobacterium avium intracellulare infection in a Persian Cat
Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2004Co-Authors: A Knippel, U Hetzel, W BaumgartnerAbstract:Summary This report describes a disseminated infection with mycobacteria of the avium/intracellulare complex in a Persian Cat in the absence of cutaneous lesions. Postmortem examination revealed severe granulomatous inflammation with numerous intrahistiocytic acid-fast bacilli in multiple organs. A gastrointestinal port of entry seems likely, as the ileocaecal lymph node was most severely affected.
-
Disseminated Mycobacterium avium–intracellulare Infection in a Persian Cat
Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health, 2004Co-Authors: A Knippel, U Hetzel, W BaumgartnerAbstract:Summary This report describes a disseminated infection with mycobacteria of the avium/intracellulare complex in a Persian Cat in the absence of cutaneous lesions. Postmortem examination revealed severe granulomatous inflammation with numerous intrahistiocytic acid-fast bacilli in multiple organs. A gastrointestinal port of entry seems likely, as the ileocaecal lymph node was most severely affected.
Ana Maria Reis Ferreira - One of the best experts on this subject based on the ideXlab platform.
-
Recurrent pulmonary edema secondary to elongated soft palate in a Cat.
Journal of Feline Medicine and Surgery, 2012Co-Authors: Katia Barão Corgozinho, Adriana Neves Pereira, Simone Carvalho Dos Santos Cunha, Cristiane Brandão Damico, Ana Maria Reis Ferreira, Heloisa Justen Moreira De SouzaAbstract:A 9-month-old intact female Persian Cat presented with recurrent pulmonary edema secondary to an elongated soft palate. Endoscopic evaluation of the pharynx and larynx showed that the elongated soft palate was overlying the epiglottis. Partial resection of the soft palate was performed and the Cat showed no further respiratory signs. This report is the first description of elongated soft palate causing airway obstruction in a brachycephalic Cat.
-
dermatophytic pseudomycetoma caused by microsporum canis in a Persian Cat
2006Co-Authors: Adriana Neves Pereira, Cristiane Brandão Damico, Katia Barao, Roberta Graca, Elan Cardoso, Paes De Almeida, Ana Maria Reis FerreiraAbstract:Dermatophytic pseudomycetoma is rare fungal infection, which has been described in Cats and men and recently in dogs and horses. Most cases, Microsporum canis is the fungi isolated. In the present article report one case of dermatophytic pseudomycetoma in Persion Cat. Lesions were characterized by nodules ranged from 1.0 to 1.5 cm in diameter, firm, irregularly shaped. Histologically, lesions are presented by deep granulomatous dermatitis, predominating macrophages, epithelioid cells and a discrete number of plasma cells, eosinophils, and dense hyphae aggregate surrounded by marked eosinophilic SplendoriHoeppli reaction.
-
pseudomicetoma dermatofitico causado por microsporum canis em gato da raca persa dermatophytic pseudomycetoma caused by microsporum canis in a Persian Cat
2006Co-Authors: Adriana Neves Pereira, Cristiane Brandão Damico, Katia Barao, Roberta Graca, Elan Cardoso, Paes De Almeida, Heloisa Justen, Moreira De Souza, Ana Maria Reis FerreiraAbstract:Dermatophytic pseudomycetoma is rare fungal infection, which has been described in Cats and men and recently in dogs and horses. Most cases, Microsporum canis is the fungi isolated. In the present article report one case of dermatophytic pseudomycetoma in Persion Cat. Lesions were characterized by nodules ranged from 1.0 to 1.5 cm in diameter, firm, irregularly shaped. Histologically, lesions are presented by deep granulomatous dermatitis, predominating macrophages, epithelioid cells and a discrete number of plasma cells, eosinophils, and dense hyphae aggregate surrounded by marked eosinophilic SplendoriHoeppli reaction.