The Experts below are selected from a list of 291 Experts worldwide ranked by ideXlab platform
Girija G. Konduri - One of the best experts on this subject based on the ideXlab platform.
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considerations in the management of hypoxemic respiratory failure and Persistent Pulmonary Hypertension in term and late preterm neonates
Journal of Perinatology, 2016Co-Authors: Satyanarayana Lakshminrusimha, Girija G. Konduri, Robin H SteinhornAbstract:Considerations in the management of hypoxemic respiratory failure and Persistent Pulmonary Hypertension in term and late preterm neonates
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Altered prostanoid metabolism contributes to impaired angiogenesis in Persistent Pulmonary Hypertension in a fetal lamb model.
Pediatric Research, 2014Co-Authors: Chaitali N. Mahajan, Adeleye J. Afolayan, Ru-jeng Teng, Girija G. KonduriAbstract:Altered prostanoid metabolism contributes to impaired angiogenesis in Persistent Pulmonary Hypertension in a fetal lamb model
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Antenatal betamethasone improves postnatal transition in late preterm lambs with Persistent Pulmonary Hypertension of the newborn.
Pediatric Research, 2013Co-Authors: Girija G. Konduri, Ivane Bakhutashvili, Adeleye J. AfolayanAbstract:Antenatal betamethasone improves postnatal transition in late preterm lambs with Persistent Pulmonary Hypertension of the newborn
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oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with Persistent Pulmonary Hypertension
American Journal of Physiology-heart and Circulatory Physiology, 2007Co-Authors: Girija G. Konduri, Ivane Bakhutashvili, Kirkwood A PritchardAbstract:Persistent Pulmonary Hypertension of newborn (PPHN) is associated with decreased NO release and impaired Pulmonary vasodilation. We investigated the hypothesis that increased superoxide (O2•−) rele...
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new approaches for Persistent Pulmonary Hypertension of newborn
Clinics in Perinatology, 2004Co-Authors: Girija G. KonduriAbstract:The management of Persistent Pulmonary Hypertension of newborn (PPHN) has seen remarkable advances in the recent years that have led to significant decreases in mortality and morbidity from this condition [1–4]. PPHN occurs when the Pulmonary vascular resistance (PVR) fails to decrease at birth. The elevated Pulmonary artery pressure decreases Pulmonary blood flow and leads to right-to-left shunting across the patent ductus arteriosus or the patent foramen ovale. Because of the presence of these fetal shunts, this condition was also referred to in the past as Persistent fetal circulation. However, right-to-left shunting can occur without PPHN, as in congenital heart diseases with left heart hypoplasia or obstruction. PPHN is therefore a more appropriate term for noncardiac causes of cyanosis with elevated PVR in term and near-term infants. The incidence of PPHN is estimated to be around 0.2% of term infants [2], with higher incidence in pregnancies with no prenatal care and with the use of tobacco and illicit drugs [2]. Conditions associated with Persistent Pulmonary Hypertension of newborn PPHN can occur without associated parenchymal lung disease (idiopathic) or with a variety of lung diseases. PPHN occurs most commonly in association with meconium aspiration syndrome (50%), followed by idiopathic PPHN (20%), pneumonia/sepsis (20%), respiratory distress syndrome (5%), and other causes (asphyxia, maternal diabetes, polycythemia, etc) [2,4]. Alveolar-capillary dysplasia, a developmental defect in the proper alignment of alveoli and Pulmonary vessels to form the air-blood barrier, is being increasingly recognized in lethal cases of PPHN [5]. Congenital diaphragmatic hernia (CDH) is also often associated with PPHN [6]. However, infants with CDH have severe underlying
Kirkwood A Pritchard - One of the best experts on this subject based on the ideXlab platform.
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oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with Persistent Pulmonary Hypertension
American Journal of Physiology-heart and Circulatory Physiology, 2007Co-Authors: Girija G. Konduri, Ivane Bakhutashvili, Kirkwood A PritchardAbstract:Persistent Pulmonary Hypertension of newborn (PPHN) is associated with decreased NO release and impaired Pulmonary vasodilation. We investigated the hypothesis that increased superoxide (O2•−) rele...
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decreased association of hsp90 impairs endothelial nitric oxide synthase in fetal lambs with Persistent Pulmonary Hypertension
American Journal of Physiology-heart and Circulatory Physiology, 2003Co-Authors: Girija G. Konduri, Jingsong Ou, Kirkwood A PritchardAbstract:Persistent Pulmonary Hypertension of newborn (PPHN) is associated with decreased nitric oxide (NO) release and impaired Pulmonary vasodilation. We investigated the hypothesis that decreased associa...
Robin H Steinhorn - One of the best experts on this subject based on the ideXlab platform.
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considerations in the management of hypoxemic respiratory failure and Persistent Pulmonary Hypertension in term and late preterm neonates
Journal of Perinatology, 2016Co-Authors: Satyanarayana Lakshminrusimha, Girija G. Konduri, Robin H SteinhornAbstract:Considerations in the management of hypoxemic respiratory failure and Persistent Pulmonary Hypertension in term and late preterm neonates
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the myocardial architecture changes in Persistent Pulmonary Hypertension of the newborn in an ovine animal model
Pediatric Research, 2016Co-Authors: Peter Agger, Satyanarayana Lakshminrusimha, Christoffer Laustsen, Sylvia F Gugino, Jesper Frandsen, Morten Smerup, Robert H Anderson, Vibeke E Hjortdal, Robin H SteinhornAbstract:The myocardial architecture changes in Persistent Pulmonary Hypertension of the newborn in an ovine animal model
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hydrocortisone normalizes oxygenation and cgmp regulation in lambs with Persistent Pulmonary Hypertension of the newborn
American Journal of Physiology-lung Cellular and Molecular Physiology, 2012Co-Authors: Marta Perez, Satyanarayana Lakshminrusimha, Sylvia F Gugino, Stephen Wedgwood, Lyubov Czech, James A Russell, Kathryn N Farrow, Robin H SteinhornAbstract:In the Pulmonary vasculature, cGMP levels are regulated by soluble guanylate cyclase (sGC) and phosphodiesterase 5 (PDE5). We previously reported that lambs with Persistent Pulmonary Hypertension o...
Viktoria Sjoblom - One of the best experts on this subject based on the ideXlab platform.
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selective serotonin reuptake inhibitors and Persistent Pulmonary Hypertension of the newborn
The New England Journal of Medicine, 2006Co-Authors: Par Hallberg, Viveca Odlind, Viktoria SjoblomAbstract:Selective serotonin-reuptake inhibitors and Persistent Pulmonary Hypertension of the newborn
Par Hallberg - One of the best experts on this subject based on the ideXlab platform.
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selective serotonin reuptake inhibitors and Persistent Pulmonary Hypertension of the newborn
The New England Journal of Medicine, 2006Co-Authors: Par Hallberg, Viveca Odlind, Viktoria SjoblomAbstract:Selective serotonin-reuptake inhibitors and Persistent Pulmonary Hypertension of the newborn