The Experts below are selected from a list of 1197 Experts worldwide ranked by ideXlab platform
Apurba Datta - One of the best experts on this subject based on the ideXlab platform.
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Stereoselective synthesis of chloramphenicol from D-serine
Tetrahedron Letters, 1998Co-Authors: G. Veeresa, Apurba DattaAbstract:Abstract An efficient synthesis of the widely used antibiotic chloramphenicol ( 1 ) is described. The key step in the synthesis involves chelation-controlled addition of Phenylmagnesium Bromide to a suitably protected D-serinal derivative, affording the pivotal D- threo 1,2-amino alcohol intermediate 3 in a highly stereoselective manner.
G. Veeresa - One of the best experts on this subject based on the ideXlab platform.
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Stereoselective synthesis of chloramphenicol from D-serine
Tetrahedron Letters, 1998Co-Authors: G. Veeresa, Apurba DattaAbstract:Abstract An efficient synthesis of the widely used antibiotic chloramphenicol ( 1 ) is described. The key step in the synthesis involves chelation-controlled addition of Phenylmagnesium Bromide to a suitably protected D-serinal derivative, affording the pivotal D- threo 1,2-amino alcohol intermediate 3 in a highly stereoselective manner.
Jeffrey S. Johnson - One of the best experts on this subject based on the ideXlab platform.
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Organic Syntheses - Copper‐Catalyzed Electrophilic Amination of Diorganozinc Reagents: 4‐Phenylmorpholine
Organic Syntheses, 2006Co-Authors: Ashley M. Berman, Jeffrey S. JohnsonAbstract:Benzoyl peroxide Phenylmagnesium Bromide 4-Benzoyloxymorpholine 4-Phenylmorpholine Keywords: copper catalyst; amination; phenylmorpholine; diorganozinc reagents; Buchwald-Hartwig coupling; electrophilic amination; diarylzinc reagents
Max Robba - One of the best experts on this subject based on the ideXlab platform.
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Pyrrolo[1,2-a][1,4] benzodiazepines : An original three-step synthesis from anthranilonitrile.
Tetrahedron Letters, 1993Co-Authors: I. Rault, Sylvain Rault, Max RobbaAbstract:Abstract Reaction of Phenylmagnesium Bromide with 2-(1-pyrrolyl) benzonitrile leads to a stable imine wich easily produces new pyrrolo[1,2-a][1,4] benzodiazepin
Ashley M. Berman - One of the best experts on this subject based on the ideXlab platform.
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Organic Syntheses - Copper‐Catalyzed Electrophilic Amination of Diorganozinc Reagents: 4‐Phenylmorpholine
Organic Syntheses, 2006Co-Authors: Ashley M. Berman, Jeffrey S. JohnsonAbstract:Benzoyl peroxide Phenylmagnesium Bromide 4-Benzoyloxymorpholine 4-Phenylmorpholine Keywords: copper catalyst; amination; phenylmorpholine; diorganozinc reagents; Buchwald-Hartwig coupling; electrophilic amination; diarylzinc reagents