The Experts below are selected from a list of 2955 Experts worldwide ranked by ideXlab platform
Jon C Antilla - One of the best experts on this subject based on the ideXlab platform.
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chiral magnesium binol phosphate catalyzed phosphination of imines access to enantioenriched α amino phosphine oxides
ChemInform, 2011Co-Authors: Gajendrasingh K Ingle, Yuxue Liang, Michael G Mormino, Frank R Fronczek, Jon C AntillaAbstract:The use of phosphine oxides bearing aromatic substituents allows the preparation of a broad spectrum of biologically interesting target compounds.
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chiral magnesium binol phosphate catalyzed phosphination of imines access to enantioenriched α amino phosphine oxides
Organic Letters, 2011Co-Authors: Gajendrasingh K Ingle, Yuxue Liang, Michael G Mormino, Frank R Fronczek, Jon C AntillaAbstract:A new method to synthesize chiral α-amino phosphine oxides is reported. The reaction combines N-substituted imines and diphenylphosphine oxide and is catalyzed by a chiral magnesium phosphate salt. A wide variety of aliphatic and aromatic aldimines substituted by electron-neutral benzhydryl or dibenzocycloheptene groups were excellent substrates for the addition reaction. The dibenzocycloheptene protected imines afforded improved enantioselectivity in the resulting products. Substituted diphenylphosphine oxide nucleophiles also showed good reactivity.
Herve Bricout - One of the best experts on this subject based on the ideXlab platform.
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amphiphilic photo isomerisable Phosphanes for aqueous organometallic catalysis
Chemical Communications, 2010Co-Authors: Herve Bricout, Estelle Banaszak, Frédéric Hapiot, Eric MonflierAbstract:Water-soluble Phosphanes were tagged with a light-responding diazo group. Upon UV exposure, the diazo-isomerisation led to Phosphane morphology change, resulting in an increase in the reaction rate of an aqueous palladium-catalysed cleavage reaction.
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properties and catalytic activities of new easily made amphiphilic Phosphanes for aqueous organometallic catalysis
Advanced Synthesis & Catalysis, 2010Co-Authors: Nathalie Azaroual, Michel Ferreira, Herve Bricout, Cédric Gaillard, David LandyAbstract:Mono- and disulfonated amphiphilic versions of triphenylPhosphane (PPh3) and cyclohexyl(phenyl)Phosphane were easily synthesized from commercial reagents and sulfuric acid. The behaviour of these Phosphanes in solution was investigated by surface tension, isothermal titration calorimetry, nuclear magnetic resonance and cryo-transmission electron microscopy. Two different supramolecular assemblies were evidenced according to the degree of sulfonation. The monosulfonated Phosphanes formed well organized micelle-like aggregates while the disulfonated Phosphanes formed heterogeneous and disorganized vesicle-like assemblies. The efficiency of these amphiphilic Phosphanes was evaluated in the aqueous biphasic, palladium-catalyzed cleavage of allyl alkyl carbonates.
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supramolecular trapping of Phosphanes by cyclodextrins a general approach to generate Phosphane coordinatively unsaturated organometallic complexes
European Journal of Inorganic Chemistry, 2006Co-Authors: Cecile Binkowskimachut, Michael Canipelle, Herve Bricout, Sebastien Tilloy, Frédéric Hapiot, Eric MonflierAbstract:As shown by 31P{1H} NMR spectroscopy, addition of the native β-cyclodextrin or randomly methylated β-cyclodextrin to an aqueous solution of Cl[Pt{(p-tBuC6H4)P(m-C6H4SO3Na)2}3Cl] or [Pd{(p-tBuC6H4)P(m-C6H4SO3Na)2}3] allows us to generate the Phosphane coordinatively unsaturated [Pt{(p-tBuC6H4)P(m-C6H4SO3Na)2}2Cl2] or [Pd{(p-tBuC6H4)P(m-C6H4SO3Na)2}2] complexes, respectively. The existence of second-sphere coordination adducts between the organometallic complex and the cyclodextrin, in which the local bulkiness around the metallic centre is high, appears to be the essential prerequisite for the dissociation of one (p-tBuC6H4)P(m-C6H4SO3Na)2 Phosphane ligand from the metal centre. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Gajendrasingh K Ingle - One of the best experts on this subject based on the ideXlab platform.
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chiral magnesium binol phosphate catalyzed phosphination of imines access to enantioenriched α amino phosphine oxides
ChemInform, 2011Co-Authors: Gajendrasingh K Ingle, Yuxue Liang, Michael G Mormino, Frank R Fronczek, Jon C AntillaAbstract:The use of phosphine oxides bearing aromatic substituents allows the preparation of a broad spectrum of biologically interesting target compounds.
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chiral magnesium binol phosphate catalyzed phosphination of imines access to enantioenriched α amino phosphine oxides
Organic Letters, 2011Co-Authors: Gajendrasingh K Ingle, Yuxue Liang, Michael G Mormino, Frank R Fronczek, Jon C AntillaAbstract:A new method to synthesize chiral α-amino phosphine oxides is reported. The reaction combines N-substituted imines and diphenylphosphine oxide and is catalyzed by a chiral magnesium phosphate salt. A wide variety of aliphatic and aromatic aldimines substituted by electron-neutral benzhydryl or dibenzocycloheptene groups were excellent substrates for the addition reaction. The dibenzocycloheptene protected imines afforded improved enantioselectivity in the resulting products. Substituted diphenylphosphine oxide nucleophiles also showed good reactivity.
Michel Ferreira - One of the best experts on this subject based on the ideXlab platform.
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properties and catalytic activities of new easily made amphiphilic Phosphanes for aqueous organometallic catalysis
Advanced Synthesis & Catalysis, 2010Co-Authors: Nathalie Azaroual, Michel Ferreira, Herve Bricout, Cédric Gaillard, David LandyAbstract:Mono- and disulfonated amphiphilic versions of triphenylPhosphane (PPh3) and cyclohexyl(phenyl)Phosphane were easily synthesized from commercial reagents and sulfuric acid. The behaviour of these Phosphanes in solution was investigated by surface tension, isothermal titration calorimetry, nuclear magnetic resonance and cryo-transmission electron microscopy. Two different supramolecular assemblies were evidenced according to the degree of sulfonation. The monosulfonated Phosphanes formed well organized micelle-like aggregates while the disulfonated Phosphanes formed heterogeneous and disorganized vesicle-like assemblies. The efficiency of these amphiphilic Phosphanes was evaluated in the aqueous biphasic, palladium-catalyzed cleavage of allyl alkyl carbonates.
Eric Monflier - One of the best experts on this subject based on the ideXlab platform.
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amphiphilic photo isomerisable Phosphanes for aqueous organometallic catalysis
Chemical Communications, 2010Co-Authors: Herve Bricout, Estelle Banaszak, Frédéric Hapiot, Eric MonflierAbstract:Water-soluble Phosphanes were tagged with a light-responding diazo group. Upon UV exposure, the diazo-isomerisation led to Phosphane morphology change, resulting in an increase in the reaction rate of an aqueous palladium-catalysed cleavage reaction.
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supramolecular trapping of Phosphanes by cyclodextrins a general approach to generate Phosphane coordinatively unsaturated organometallic complexes
European Journal of Inorganic Chemistry, 2006Co-Authors: Cecile Binkowskimachut, Michael Canipelle, Herve Bricout, Sebastien Tilloy, Frédéric Hapiot, Eric MonflierAbstract:As shown by 31P{1H} NMR spectroscopy, addition of the native β-cyclodextrin or randomly methylated β-cyclodextrin to an aqueous solution of Cl[Pt{(p-tBuC6H4)P(m-C6H4SO3Na)2}3Cl] or [Pd{(p-tBuC6H4)P(m-C6H4SO3Na)2}3] allows us to generate the Phosphane coordinatively unsaturated [Pt{(p-tBuC6H4)P(m-C6H4SO3Na)2}2Cl2] or [Pd{(p-tBuC6H4)P(m-C6H4SO3Na)2}2] complexes, respectively. The existence of second-sphere coordination adducts between the organometallic complex and the cyclodextrin, in which the local bulkiness around the metallic centre is high, appears to be the essential prerequisite for the dissociation of one (p-tBuC6H4)P(m-C6H4SO3Na)2 Phosphane ligand from the metal centre. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)