The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Cesare Mariotti - One of the best experts on this subject based on the ideXlab platform.
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successful treatment of an overlapping choriocapillaritis between multifocal choroiditis and acute zonal occult outer retinopathy azoor with adalimumab humira
International Ophthalmology, 2014Co-Authors: Piergiorgio Neri, Federico Ricci, Alfonso Giovannini, Ilir Arapi, Cecilia De Felici, Andrea Cusumano, Cesare MariottiAbstract:To report a case of overlapping choriocapillaritis that initially presented as multifocal choroiditis (MFC) but later showed features compatible with acute zonal occult outer retinopathy (AZOOR) resistant to standard immunosuppression that responded only to adalimumad therapy. A 41-year-old patient presented with multiple small, discrete yellow-whitish spots in both eyes, compatible with MFC. A few weeks later, despite treatment with sub-Tenon and systemic corticosteroids, a choroidal neovascularization occurred in the right eye. The patient was treated with intravitreal anti-vascular endothelial growth factor. After 2 months, reduced visual acuity, Photopsia and visual field defect in the left eye occurred. Spectral domain optical coherence tomography revealed photoreceptor outer segment defects common to all choriocapillaritis. The additional finding of an annular scotoma and a 360° ring on indocyanine green angiography led us to make the diagnosis of presumed AZOOR. Despite the combination of several immunosuppressive agents leading to temporary control of the disease, the patient experienced a further worsening. At that point, adalimumab was introduced, which led to an obvious improvement. This case supports the hypothesis that two different entities of the so-called AZOOR complex can be possible in the same eye, even asynchronously. In our case, anti-tumor necrosis factor alpha monoclonal antibody therapy represented a valid treatment option in a patient unresponsive to traditional immunosuppressive treatments.
Joseph Carroll - One of the best experts on this subject based on the ideXlab platform.
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using spectral domain optical coherence tomography to follow outer retinal structure changes in a patient with recurrent punctate inner choroidopathy
Journal of Ophthalmology, 2011Co-Authors: Kimberly E. Stepien, Joseph CarrollAbstract:Punctate inner choroidopathy (PIC) is a rare idiopathic inflammatory disorder of the retina and choroid usually affecting healthy, young, myopic females and presenting with Photopsia, paracentral scotomata, and blurred vision. It is characterized by yellow-white chorioretinal lesions concentrated in the posterior pole, no vitritis, relapsing inflammatory activity of the retina and choroid, and frequent development of choroidal neovascular membranes. Here we describe a case in which spectral-domain optical coherence tomography (SD-OCT) imaging was used to monitor outer retinal structure changes associated with recurrent PIC over time. SD-OCT, which is both quantative and objective, provides an efficient, non-invasive way to follow recurrent inflammatory chorioretinal lesion activity, choroidal neovascular membrane development, and treatment response in patients with recurrent PIC.
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Using Spectral-Domain Optical Coherence Tomography to Follow Outer Retinal Structure Changes in a Patient with Recurrent Punctate Inner Choroidopathy
2011Co-Authors: Kimberly E. Stepien, Joseph CarrollAbstract:License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Punctate inner choroidopathy (PIC) is a rare idiopathic inflammatory disorder of the retina and choroid usually affecting healthy, young, myopic females and presenting with Photopsia, paracentral scotomata, and blurred vision. It is characterized by yellow-white chorioretinal lesions concentrated in the posterior pole, no vitritis, relapsing inflammatory activity of the retina and choroid, and frequent development of choroidal neovascular membranes. Here we describe a case in which spectral-domain optical coher-ence tomography (SD-OCT) imaging was used to monitor outer retinal structure changes associated with recurrent PIC over time. SD-OCT, which is both quantative and objective, provides an efficient, non-invasive way to follow recurrent inflammatory chorioretinal lesion activity, choroidal neovascular membrane development, and treatment response in patients with recurrent PIC. 1. Report of a Case: A 21-year-old white myopic female with a history of sym-ptomatic punctate inner choroidopathy (PIC) presented with new Photopsias and scotoma in her left eye for several days. She had been symptomatic in her right eye for one year wit
Piergiorgio Neri - One of the best experts on this subject based on the ideXlab platform.
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successful treatment of an overlapping choriocapillaritis between multifocal choroiditis and acute zonal occult outer retinopathy azoor with adalimumab humira
International Ophthalmology, 2014Co-Authors: Piergiorgio Neri, Federico Ricci, Alfonso Giovannini, Ilir Arapi, Cecilia De Felici, Andrea Cusumano, Cesare MariottiAbstract:To report a case of overlapping choriocapillaritis that initially presented as multifocal choroiditis (MFC) but later showed features compatible with acute zonal occult outer retinopathy (AZOOR) resistant to standard immunosuppression that responded only to adalimumad therapy. A 41-year-old patient presented with multiple small, discrete yellow-whitish spots in both eyes, compatible with MFC. A few weeks later, despite treatment with sub-Tenon and systemic corticosteroids, a choroidal neovascularization occurred in the right eye. The patient was treated with intravitreal anti-vascular endothelial growth factor. After 2 months, reduced visual acuity, Photopsia and visual field defect in the left eye occurred. Spectral domain optical coherence tomography revealed photoreceptor outer segment defects common to all choriocapillaritis. The additional finding of an annular scotoma and a 360° ring on indocyanine green angiography led us to make the diagnosis of presumed AZOOR. Despite the combination of several immunosuppressive agents leading to temporary control of the disease, the patient experienced a further worsening. At that point, adalimumab was introduced, which led to an obvious improvement. This case supports the hypothesis that two different entities of the so-called AZOOR complex can be possible in the same eye, even asynchronously. In our case, anti-tumor necrosis factor alpha monoclonal antibody therapy represented a valid treatment option in a patient unresponsive to traditional immunosuppressive treatments.
Lira, Rodrigo Pessoa Cavalcanti - One of the best experts on this subject based on the ideXlab platform.
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Introflexão escleral é boa opção para tratamento de descolamento de retina não complicado
Sociedade Brasileira de Oftalmologia, 2015Co-Authors: Takasaka Iuuki, Chaves, Fernando Rodrigo Pedreira, Panetta Heitor, Torigoe, Andrea Mara Simões, Silva, Valdir Balarin, Lira, Rodrigo Pessoa CavalcantiAbstract:OBJETIVE: To describe the reattachment rate and visual acuity results of patients with uncomplicated rhegmatogenous retinal detachment who underwent segmental scleral buckle surgery. METHODS: Prospective case series of 100 patients with visual loss or symptoms (floaters and Photopsia) of less than 30 days' duration scheduled for surgery. No patient had a retinal break greater than 30°, a retinal detachment larger than 2 quadrants or proliferative vitreoretinopathy. RESULTS: The 1-week, 1-month, and 6-month anatomical success rates were 93%, 100%, and 100%, respectively. Seven patients underwent one additional retinal detachment surgery (pars plan vitrectomy) after primary failure at 1-week follow-up. The preoperative, 1-month, and 6-month best correct visual acuity were 20/100, 20/80, and 20/50, respectively. The postoperative complications were: eyelid edema in 10% of the patients, transient ocular hypertension in 5%, macular pucker in 3%, transient diplopia in 3%, and hyphema (
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Scleral buckle is good option for treatment of uncomplicated retinal detachment
Sociedade Brasileira de Oftalmologia, 2012Co-Authors: Chaves, Fernando Rodrigo Pedreira, Torigoe, Andrea Mara Simões, Silva, Valdir Balarin, Lira, Rodrigo Pessoa CavalcantiAbstract:OBJETIVE: To describe the reattachment rate and visual acuity results of patients with uncomplicated rhegmatogenous retinal detachment who underwent segmental scleral buckle surgery. METHODS: Prospective case series of 100 patients with visual loss or symptoms (floaters and Photopsia) of less than 30 days' duration scheduled for surgery. No patient had a retinal break greater than 30°, a retinal detachment larger than 2 quadrants or proliferative vitreoretinopathy. RESULTS: The 1-week, 1-month, and 6-month anatomical success rates were 93%, 100%, and 100%, respectively. Seven patients underwent one additional retinal detachment surgery (pars plan vitrectomy) after primary failure at 1-week follow-up. The preoperative, 1-month, and 6-month best correct visual acuity were 20/100, 20/80, and 20/50, respectively. The postoperative complications were: eyelid edema in 10% of the patients, transient ocular hypertension in 5%, macular pucker in 3%, transient diplopia in 3%, and hyphema (
Donald J M Gass - One of the best experts on this subject based on the ideXlab platform.
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multifocal choroiditis and choroidal neovascularization associated with the multiple evanescent white dot and acute idiopathic blind spot enlargement syndrome
Ophthalmology, 1992Co-Authors: David Callanan, Donald J M GassAbstract:Background: Several recent articles have described syndromes in which there is enlargement of the blind spot associated with retinal lesions. These have included the multiple evanescent white dot syndrome, acute macular neuroretinopathy, acute idiopathic blind spot enlargement syndrome, and multifocal choroiditis or pseudo presumed ocular histoplasmosis syndrome (pseudo POHS). Methods: The authors reviewed the records of seven patients in whom signs and symptoms of acute enlargement of the blind spot and pseudo POHS developed. Results: All seven patients had Photopsia accompanying enlargement of the blind spot during their illness. Four had transient white spots as seen in the multiple evanescent white dot syndrome. All presented with or developed chorioretinal scars or neovascularization similar to that seen in multifocal choroiditis or pseudo POHS. In four of the seven patients, POHS-like scars developed only in the eye that was symptomatic with blind spot enlargement and Photopsia. Five of the 7 had visual acuity of 20/25 or better at the last follow-up. Conclusion: It would appear that there is an overlap in the clinical findings of all of these syndromes and that there may be a common link in their etiology.