The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
Vladimir A. Galishev - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of benzo[4,5]imidazo[2,1-a]Phthalazines
Tetrahedron Letters, 2004Co-Authors: Kirill M. Shubin, Viktor A. Kuznetsov, Vladimir A. GalishevAbstract:5,9-Disubstituted benzo[4,5]imidazo[2,1-a]Phthalazines are synthesized efficiently from acylbenzoic acids and 2-nitro-5-chlorophenylhydrazine. Nucleophilic substitution in phthalazinones gave a variety of the title compounds after reduction and cyclization.
Kirill M. Shubin - One of the best experts on this subject based on the ideXlab platform.
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Efficient route to benzo[4,5]imidazo[2,1-a]Phthalazines
Tetrahedron, 2006Co-Authors: Viktor A. Kuznetsov, Kirill M. Shubin, Andrej A. Schipalkin, Mikhail L. PetrovAbstract:Abstract Benzo[4,5]imidazo[2,1- a ]Phthalazines have been obtained from various o -nitrophenylhydrazines through different 2-(2-nitrophenyl)-1,2-dihydro-1-phthalazinones as intermediates using an elaborated advanced procedure. An activated chlorine atom in 2-nitrophenyl moiety of the latter is able to undergo nucleophilic substitution for secondary alicyclic amines yielding novel substituted phthalazinones. Their one-pot reduction and cyclodehydration yield a series of novel substituted benzo[4,5]imidazo[2,1- a ]Phthalazines.
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Synthesis of benzo[4,5]imidazo[2,1-a]Phthalazines
Tetrahedron Letters, 2004Co-Authors: Kirill M. Shubin, Viktor A. Kuznetsov, Vladimir A. GalishevAbstract:5,9-Disubstituted benzo[4,5]imidazo[2,1-a]Phthalazines are synthesized efficiently from acylbenzoic acids and 2-nitro-5-chlorophenylhydrazine. Nucleophilic substitution in phthalazinones gave a variety of the title compounds after reduction and cyclization.
Viktor A. Kuznetsov - One of the best experts on this subject based on the ideXlab platform.
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Efficient route to benzo[4,5]imidazo[2,1-a]Phthalazines
Tetrahedron, 2006Co-Authors: Viktor A. Kuznetsov, Kirill M. Shubin, Andrej A. Schipalkin, Mikhail L. PetrovAbstract:Abstract Benzo[4,5]imidazo[2,1- a ]Phthalazines have been obtained from various o -nitrophenylhydrazines through different 2-(2-nitrophenyl)-1,2-dihydro-1-phthalazinones as intermediates using an elaborated advanced procedure. An activated chlorine atom in 2-nitrophenyl moiety of the latter is able to undergo nucleophilic substitution for secondary alicyclic amines yielding novel substituted phthalazinones. Their one-pot reduction and cyclodehydration yield a series of novel substituted benzo[4,5]imidazo[2,1- a ]Phthalazines.
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Synthesis of benzo[4,5]imidazo[2,1-a]Phthalazines
Tetrahedron Letters, 2004Co-Authors: Kirill M. Shubin, Viktor A. Kuznetsov, Vladimir A. GalishevAbstract:5,9-Disubstituted benzo[4,5]imidazo[2,1-a]Phthalazines are synthesized efficiently from acylbenzoic acids and 2-nitro-5-chlorophenylhydrazine. Nucleophilic substitution in phthalazinones gave a variety of the title compounds after reduction and cyclization.
Maya Shankar Singh - One of the best experts on this subject based on the ideXlab platform.
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solvent free sonochemical one pot three component synthesis of 2h indazolo 2 1 b phthalazine 1 6 11 triones and 1h pyrazolo 1 2 b phthalazine 5 10 diones
Tetrahedron Letters, 2011Co-Authors: Gaurav Shukla, Rajiv Kumar Verma, Girijesh Kumar Verma, Maya Shankar SinghAbstract:Abstract A rapid and efficient one-pot three-component protocol for the synthesis of 2 H -indazolo[2,1- b ]phthalazine-1,6,11-triones 4 and 1 H -pyrazolo[1,2- b ]phthalazine-5,10-diones 6 has been developed by domino coupling of phthalhydrazide, 1,3-diketones, and aldehydes under solvent-free conditions at 80 °C as well as under solvent-free ultrasound irradiation at room temperature promoted by ( S )-camphorsulfonic acid.
Philippe Belmont - One of the best experts on this subject based on the ideXlab platform.
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Visible light amination/Smiles cascade: access to phthalazine derivatives.
Chemical Science, 2016Co-Authors: Etienne Brachet, Leyre Marzo, Mohamed Selkti, Burkhard König, Philippe BelmontAbstract:We report the synthesis of various Phthalazines via a new cascade reaction, initiated by visible light photocatalysis, involving a radical hydroamination reaction followed by a radical Smiles rearrangement. Phthalazine derivatives are obtained in high yields and from a broad scope readily accessible ortho-alkynylsulfonohydrazone precursors. The mild photoredox conditions ensure an excellent functional group tolerance. Application of this strategy to a one-pot protocol starting from the corresponding carbonyl compounds, and subsequent functionalization allow the rapid synthesis of structurally diverse structures.