The Experts below are selected from a list of 8943 Experts worldwide ranked by ideXlab platform

Ina Bosselmann - One of the best experts on this subject based on the ideXlab platform.

  • retrospective analysis evaluating the effect of a keratolytic and Physical Pretreatment with salicylic acid urea and curettage on the efficacy and safety of photodynamic therapy of actinic keratoses with methylaminolaevulinate
    Journal of The European Academy of Dermatology and Venereology, 2016
    Co-Authors: Patrick Gholam, Christine Fink, Ina Bosselmann
    Abstract:

    Background Photodynamic therapy (PDT) is a highly effective treatment option for actinic keratosis (AK). Hyperkeratosis of the AK impairs penetration of the photosensitizer and light and leads to a reduced efficacy of PDT. Therefore, it is commonly recommended to perform curettage of the AK prior to treatment. Objective This observational, monocentric, retrospective study sets out to compare the effects of curettage (CUR), chemical keratolytic Pretreatment with salicylic acid 10% (SA), and urea cream 40% (UR) on the efficacy and tolerability of PDT. Method A total of 44 subjects aged 73.2 ± 7.7 years (mean ± SD) with multiple AKs (mean 11.1 per patient) in face and scalp were analysed. In 15 patients, CUR was performed prior to PDT while 15 and 14 patients underwent keratolytic Pretreatment with SA and UR, respectively, 1 day prior to PDT. All patients underwent one session of methylaminolaevulinate (MAL) PDT using a 630-nm LED lamp at 37 J/cm2, pain was measured using a visual analogue scale. The response rate was calculated using the documented number of AKs prior and 4 weeks after PDT. Results Mean lesion response rates were 68.5%, 61.4% and 60.8% for CUR, SA and UR respectively. Differences were not significant. Patients with SA or UR experienced significantly more pain (SA: 6.3 ± 2.7, P = 0.02; UR: 6.1 ± 1.8, P = 0.04) than patients with curettage (4.4 ± 2.1). The cosmetic result and the patients' satisfaction 4 weeks after PDT were good to excellent in all three groups without a significant difference. However, Pretreatment with SA or UR led to pronounced local reactions compared to CUR. Conclusion Keratolytic therapy with SA or UR is an effective Pretreatment for PDT. However, it leads to an increase in pain during PDT and pronounced local reactions.

  • retrospective analysis evaluating the effect of a keratolytic and Physical Pretreatment with salicylic acid urea and curettage on the efficacy and safety of photodynamic therapy of actinic keratoses with methylaminolaevulinate
    Journal of The European Academy of Dermatology and Venereology, 2016
    Co-Authors: Patrick Gholam, Christine Fink, Ina Bosselmann
    Abstract:

    Background Photodynamic therapy (PDT) is a highly effective treatment option for actinic keratosis (AK). Hyperkeratosis of the AK impairs penetration of the photosensitizer and light and leads to a reduced efficacy of PDT. Therefore, it is commonly recommended to perform curettage of the AK prior to treatment. Objective This observational, monocentric, retrospective study sets out to compare the effects of curettage (CUR), chemical keratolytic Pretreatment with salicylic acid 10% (SA), and urea cream 40% (UR) on the efficacy and tolerability of PDT. Method A total of 44 subjects aged 73.2 ± 7.7 years (mean ± SD) with multiple AKs (mean 11.1 per patient) in face and scalp were analysed. In 15 patients, CUR was performed prior to PDT while 15 and 14 patients underwent keratolytic Pretreatment with SA and UR, respectively, 1 day prior to PDT. All patients underwent one session of methylaminolaevulinate (MAL) PDT using a 630-nm LED lamp at 37 J/cm2, pain was measured using a visual analogue scale. The response rate was calculated using the documented number of AKs prior and 4 weeks after PDT. Results Mean lesion response rates were 68.5%, 61.4% and 60.8% for CUR, SA and UR respectively. Differences were not significant. Patients with SA or UR experienced significantly more pain (SA: 6.3 ± 2.7, P = 0.02; UR: 6.1 ± 1.8, P = 0.04) than patients with curettage (4.4 ± 2.1). The cosmetic result and the patients' satisfaction 4 weeks after PDT were good to excellent in all three groups without a significant difference. However, Pretreatment with SA or UR led to pronounced local reactions compared to CUR. Conclusion Keratolytic therapy with SA or UR is an effective Pretreatment for PDT. However, it leads to an increase in pain during PDT and pronounced local reactions.

Nurina Anuar - One of the best experts on this subject based on the ideXlab platform.

  • palm oil mill effluent pome treatment and bioresources recovery using ultrafiltration membrane effect of pressure on membrane fouling
    Biochemical Engineering Journal, 2007
    Co-Authors: Ta Yeong Wu, Abdul Wahab Mohammad, Md J Jahim, Nurina Anuar
    Abstract:

    An attempt was made to examine the effect of applied pressure on membrane fouling that might influence the potential use of ultrafiltration (UF) membrane in treating as well as recovering the bioresources, namely protein and carbohydrate from complex feed like palm oil mill effluent (POME). POME was first subjected to Physical Pretreatment processes, consisting of depth and surface filtration in order to remove the total suspended solids (TSS). The Pretreatment processes enabled the reduction of TSS, turbidity, total dissolved solid (TDS) and chemical oxygen demand (COD) up to 97.3%, 88.2%, 3.1% and 46.9%, respectively. Protein (45.3%) and carbohydrate (41.5%) that retained as insoluble matters together with suspended solids might be used as fertilizer or animal feed by-products. Then, polysulphone UF membrane of 20 kDa was used in the UF membrane study. This study indicated that the applied pressure imposed a direct effect on fouling, permeate flux, protein and carbohydrate recovery as well as wastewater treatment. In total, the permeate flux decreased with filtration time until it reached steady-state values. Beyond a certain applied pressure between 0.6 and 0.8 MPa, the increase in permeate flux with pressure was negligible and insignificance. The highest applied pressure (0.8 MPa) encouraged the formation of fouling up to 85.8% but at the same time enabled the recovery of protein and carbohydrate up to 61.4% and 76.4%, respectively. The highest reduction of TSS, turbidity, TDS and COD also occurred at 0.8 MPa up to 97.7%, 88.5%, 6.5% and 57.0%. The study revealed that it is possible to have appropriate control of applied pressure in order to favor fouling that would, in turn, lead to better rejection of other solutes present in the feed.

Patrick Gholam - One of the best experts on this subject based on the ideXlab platform.

  • retrospective analysis evaluating the effect of a keratolytic and Physical Pretreatment with salicylic acid urea and curettage on the efficacy and safety of photodynamic therapy of actinic keratoses with methylaminolaevulinate
    Journal of The European Academy of Dermatology and Venereology, 2016
    Co-Authors: Patrick Gholam, Christine Fink, Ina Bosselmann
    Abstract:

    Background Photodynamic therapy (PDT) is a highly effective treatment option for actinic keratosis (AK). Hyperkeratosis of the AK impairs penetration of the photosensitizer and light and leads to a reduced efficacy of PDT. Therefore, it is commonly recommended to perform curettage of the AK prior to treatment. Objective This observational, monocentric, retrospective study sets out to compare the effects of curettage (CUR), chemical keratolytic Pretreatment with salicylic acid 10% (SA), and urea cream 40% (UR) on the efficacy and tolerability of PDT. Method A total of 44 subjects aged 73.2 ± 7.7 years (mean ± SD) with multiple AKs (mean 11.1 per patient) in face and scalp were analysed. In 15 patients, CUR was performed prior to PDT while 15 and 14 patients underwent keratolytic Pretreatment with SA and UR, respectively, 1 day prior to PDT. All patients underwent one session of methylaminolaevulinate (MAL) PDT using a 630-nm LED lamp at 37 J/cm2, pain was measured using a visual analogue scale. The response rate was calculated using the documented number of AKs prior and 4 weeks after PDT. Results Mean lesion response rates were 68.5%, 61.4% and 60.8% for CUR, SA and UR respectively. Differences were not significant. Patients with SA or UR experienced significantly more pain (SA: 6.3 ± 2.7, P = 0.02; UR: 6.1 ± 1.8, P = 0.04) than patients with curettage (4.4 ± 2.1). The cosmetic result and the patients' satisfaction 4 weeks after PDT were good to excellent in all three groups without a significant difference. However, Pretreatment with SA or UR led to pronounced local reactions compared to CUR. Conclusion Keratolytic therapy with SA or UR is an effective Pretreatment for PDT. However, it leads to an increase in pain during PDT and pronounced local reactions.

  • retrospective analysis evaluating the effect of a keratolytic and Physical Pretreatment with salicylic acid urea and curettage on the efficacy and safety of photodynamic therapy of actinic keratoses with methylaminolaevulinate
    Journal of The European Academy of Dermatology and Venereology, 2016
    Co-Authors: Patrick Gholam, Christine Fink, Ina Bosselmann
    Abstract:

    Background Photodynamic therapy (PDT) is a highly effective treatment option for actinic keratosis (AK). Hyperkeratosis of the AK impairs penetration of the photosensitizer and light and leads to a reduced efficacy of PDT. Therefore, it is commonly recommended to perform curettage of the AK prior to treatment. Objective This observational, monocentric, retrospective study sets out to compare the effects of curettage (CUR), chemical keratolytic Pretreatment with salicylic acid 10% (SA), and urea cream 40% (UR) on the efficacy and tolerability of PDT. Method A total of 44 subjects aged 73.2 ± 7.7 years (mean ± SD) with multiple AKs (mean 11.1 per patient) in face and scalp were analysed. In 15 patients, CUR was performed prior to PDT while 15 and 14 patients underwent keratolytic Pretreatment with SA and UR, respectively, 1 day prior to PDT. All patients underwent one session of methylaminolaevulinate (MAL) PDT using a 630-nm LED lamp at 37 J/cm2, pain was measured using a visual analogue scale. The response rate was calculated using the documented number of AKs prior and 4 weeks after PDT. Results Mean lesion response rates were 68.5%, 61.4% and 60.8% for CUR, SA and UR respectively. Differences were not significant. Patients with SA or UR experienced significantly more pain (SA: 6.3 ± 2.7, P = 0.02; UR: 6.1 ± 1.8, P = 0.04) than patients with curettage (4.4 ± 2.1). The cosmetic result and the patients' satisfaction 4 weeks after PDT were good to excellent in all three groups without a significant difference. However, Pretreatment with SA or UR led to pronounced local reactions compared to CUR. Conclusion Keratolytic therapy with SA or UR is an effective Pretreatment for PDT. However, it leads to an increase in pain during PDT and pronounced local reactions.

Abdul Wahab Mohammad - One of the best experts on this subject based on the ideXlab platform.

  • performance of hydrophobic ultrafiltration membranes in the treatment and protein recovery from palm oil mill effluent pome
    Desalination and Water Treatment, 2009
    Co-Authors: Abdul Wahab Mohammad, Peng Tong Yap
    Abstract:

    An attempt was made to investigate the effect of molecular weight cut-off (MWCO) and applied pressure on the treatment and protein recovery from palm oil mill effluent (POME). Hydrophobic ultrafiltration (UF) membranes, namely polyethersulphone and polysulphone membranes were used in this study although hydrophilic membranes are generally used in the wastewater treatment and protein recovery. In order to reduce significantly the total suspended solids from POME before proceeding with the dead-end UF process, the raw effluent was first subjected to Physical Pretreatment processes (depth and surface filtrations) and microfiltration process. Then, a polysulphone UF membrane (20,000 MWCO) as well as polyethersulphone UF membranes (10,000 MWCO and 2,000 MWCO) were used in the study at different applied pressures, ranging from 1 to 10 bar. This study indicated that MWCO and applied pressure imposed a direct effect on permeate flux, POME treatment and protein recovery. In general, the hydrophobic UF membrane wit...

  • palm oil mill effluent pome treatment and bioresources recovery using ultrafiltration membrane effect of pressure on membrane fouling
    Biochemical Engineering Journal, 2007
    Co-Authors: Ta Yeong Wu, Abdul Wahab Mohammad, Md J Jahim, Nurina Anuar
    Abstract:

    An attempt was made to examine the effect of applied pressure on membrane fouling that might influence the potential use of ultrafiltration (UF) membrane in treating as well as recovering the bioresources, namely protein and carbohydrate from complex feed like palm oil mill effluent (POME). POME was first subjected to Physical Pretreatment processes, consisting of depth and surface filtration in order to remove the total suspended solids (TSS). The Pretreatment processes enabled the reduction of TSS, turbidity, total dissolved solid (TDS) and chemical oxygen demand (COD) up to 97.3%, 88.2%, 3.1% and 46.9%, respectively. Protein (45.3%) and carbohydrate (41.5%) that retained as insoluble matters together with suspended solids might be used as fertilizer or animal feed by-products. Then, polysulphone UF membrane of 20 kDa was used in the UF membrane study. This study indicated that the applied pressure imposed a direct effect on fouling, permeate flux, protein and carbohydrate recovery as well as wastewater treatment. In total, the permeate flux decreased with filtration time until it reached steady-state values. Beyond a certain applied pressure between 0.6 and 0.8 MPa, the increase in permeate flux with pressure was negligible and insignificance. The highest applied pressure (0.8 MPa) encouraged the formation of fouling up to 85.8% but at the same time enabled the recovery of protein and carbohydrate up to 61.4% and 76.4%, respectively. The highest reduction of TSS, turbidity, TDS and COD also occurred at 0.8 MPa up to 97.7%, 88.5%, 6.5% and 57.0%. The study revealed that it is possible to have appropriate control of applied pressure in order to favor fouling that would, in turn, lead to better rejection of other solutes present in the feed.

Ta Yeong Wu - One of the best experts on this subject based on the ideXlab platform.

  • palm oil mill effluent pome treatment and bioresources recovery using ultrafiltration membrane effect of pressure on membrane fouling
    Biochemical Engineering Journal, 2007
    Co-Authors: Ta Yeong Wu, Abdul Wahab Mohammad, Md J Jahim, Nurina Anuar
    Abstract:

    An attempt was made to examine the effect of applied pressure on membrane fouling that might influence the potential use of ultrafiltration (UF) membrane in treating as well as recovering the bioresources, namely protein and carbohydrate from complex feed like palm oil mill effluent (POME). POME was first subjected to Physical Pretreatment processes, consisting of depth and surface filtration in order to remove the total suspended solids (TSS). The Pretreatment processes enabled the reduction of TSS, turbidity, total dissolved solid (TDS) and chemical oxygen demand (COD) up to 97.3%, 88.2%, 3.1% and 46.9%, respectively. Protein (45.3%) and carbohydrate (41.5%) that retained as insoluble matters together with suspended solids might be used as fertilizer or animal feed by-products. Then, polysulphone UF membrane of 20 kDa was used in the UF membrane study. This study indicated that the applied pressure imposed a direct effect on fouling, permeate flux, protein and carbohydrate recovery as well as wastewater treatment. In total, the permeate flux decreased with filtration time until it reached steady-state values. Beyond a certain applied pressure between 0.6 and 0.8 MPa, the increase in permeate flux with pressure was negligible and insignificance. The highest applied pressure (0.8 MPa) encouraged the formation of fouling up to 85.8% but at the same time enabled the recovery of protein and carbohydrate up to 61.4% and 76.4%, respectively. The highest reduction of TSS, turbidity, TDS and COD also occurred at 0.8 MPa up to 97.7%, 88.5%, 6.5% and 57.0%. The study revealed that it is possible to have appropriate control of applied pressure in order to favor fouling that would, in turn, lead to better rejection of other solutes present in the feed.