The Experts below are selected from a list of 21 Experts worldwide ranked by ideXlab platform
Libo Shan - One of the best experts on this subject based on the ideXlab platform.
-
pipped at the post Pipecolic Acid Derivative identified as sar regulator
Cell, 2018Co-Authors: Libo ShanAbstract:The non-protein amino Acid Pipecolic Acid (Pip) is a lysine catabolite involved in plant systemic acquired resistance (SAR). In this issue of Cell, Hartmann et al. (2018) demonstrate that a flavin-dependent monooxygenase converts Pip to N-hydroxyPipecolic Acid (NHP), which functions as a critical metabolic regulator of SAR in Arabidopsis.
Gunter Haufe - One of the best experts on this subject based on the ideXlab platform.
-
the vinylfluoro group as an acetonyl cation equivalent stereoselective synthesis of 6 substituted 4 hydroxy Pipecolic Acid Derivatives
Journal of Organic Chemistry, 2010Co-Authors: Nirupam Purkayastha, Deepak M Shendage, Roland Frohlich, Gunter HaufeAbstract:An unprecedented cascade of reactions after Acid-catalyzed hydrolysis of tert-butyl (2S,5S)-2-tert-butyl-5-(2-fluoroallyl)-3-methyl-4-oxoimidazolidine-1-carboxylate 3a leading to Pipecolic Acid Derivative 5 is presented. The vinylfluoro group is shown to be an acetonyl cation equivalent under Acidic conditions. Interestingly, vinylchloro and vinylbromo groups do not show such transformation under the same conditions. The Pipecolic Acid Derivative 5 produced in this way is further used to synthesize (2R,4R,6S)-6-tert-butyl-4-hydroxypiperidine-2-carboxylic Acid 9.
Nirupam Purkayastha - One of the best experts on this subject based on the ideXlab platform.
-
the vinylfluoro group as an acetonyl cation equivalent stereoselective synthesis of 6 substituted 4 hydroxy Pipecolic Acid Derivatives
Journal of Organic Chemistry, 2010Co-Authors: Nirupam Purkayastha, Deepak M Shendage, Roland Frohlich, Gunter HaufeAbstract:An unprecedented cascade of reactions after Acid-catalyzed hydrolysis of tert-butyl (2S,5S)-2-tert-butyl-5-(2-fluoroallyl)-3-methyl-4-oxoimidazolidine-1-carboxylate 3a leading to Pipecolic Acid Derivative 5 is presented. The vinylfluoro group is shown to be an acetonyl cation equivalent under Acidic conditions. Interestingly, vinylchloro and vinylbromo groups do not show such transformation under the same conditions. The Pipecolic Acid Derivative 5 produced in this way is further used to synthesize (2R,4R,6S)-6-tert-butyl-4-hydroxypiperidine-2-carboxylic Acid 9.
Deepak M Shendage - One of the best experts on this subject based on the ideXlab platform.
-
the vinylfluoro group as an acetonyl cation equivalent stereoselective synthesis of 6 substituted 4 hydroxy Pipecolic Acid Derivatives
Journal of Organic Chemistry, 2010Co-Authors: Nirupam Purkayastha, Deepak M Shendage, Roland Frohlich, Gunter HaufeAbstract:An unprecedented cascade of reactions after Acid-catalyzed hydrolysis of tert-butyl (2S,5S)-2-tert-butyl-5-(2-fluoroallyl)-3-methyl-4-oxoimidazolidine-1-carboxylate 3a leading to Pipecolic Acid Derivative 5 is presented. The vinylfluoro group is shown to be an acetonyl cation equivalent under Acidic conditions. Interestingly, vinylchloro and vinylbromo groups do not show such transformation under the same conditions. The Pipecolic Acid Derivative 5 produced in this way is further used to synthesize (2R,4R,6S)-6-tert-butyl-4-hydroxypiperidine-2-carboxylic Acid 9.
Roland Frohlich - One of the best experts on this subject based on the ideXlab platform.
-
the vinylfluoro group as an acetonyl cation equivalent stereoselective synthesis of 6 substituted 4 hydroxy Pipecolic Acid Derivatives
Journal of Organic Chemistry, 2010Co-Authors: Nirupam Purkayastha, Deepak M Shendage, Roland Frohlich, Gunter HaufeAbstract:An unprecedented cascade of reactions after Acid-catalyzed hydrolysis of tert-butyl (2S,5S)-2-tert-butyl-5-(2-fluoroallyl)-3-methyl-4-oxoimidazolidine-1-carboxylate 3a leading to Pipecolic Acid Derivative 5 is presented. The vinylfluoro group is shown to be an acetonyl cation equivalent under Acidic conditions. Interestingly, vinylchloro and vinylbromo groups do not show such transformation under the same conditions. The Pipecolic Acid Derivative 5 produced in this way is further used to synthesize (2R,4R,6S)-6-tert-butyl-4-hydroxypiperidine-2-carboxylic Acid 9.