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Martin Buckley - One of the best experts on this subject based on the ideXlab platform.

  • argon Plasma Coagulation as first line treatment for chronic radiation proctopathy
    Journal of Gastroenterology and Hepatology, 2004
    Co-Authors: Shaji Sebastian, Humphrey J Oconnor, C Omorain, Martin Buckley
    Abstract:

    Background and Aim:  Chronic radiation proctopathy is a troublesome complication of radiotherapy to the pelvis, for which current treatment modalities are unsatisfactory. The present prospective study was designed to determine the usefulness and safety of argon Plasma Coagulation in the management of chronic radiation proctopathy. Methods:  Twenty-five consecutive patients (M:F 24:1, mean age: 69 years) with radiation proctopathy were prospectively included. All patients received argon Plasma Coagulation by a standard protocol. Response to treatment was assessed by symptom response, bleeding severity score, hematological parameters and transfusion requirements over a median 14-month follow up. Results:  Patients received a median of one treatment session with argon Plasma Coagulation. There was significant improvement in rectal bleeding in all patients, with complete cessation of bleeding in 21 (81%) of the patients. The median bleeding severity score fell from 3 to 0 (P < 0.0005). The mean hemoglobin level rose from 10.05 ± 2.21 g/dL before treatment to 12.44 ± 1.09 g/dL at 6 months following treatment (P < 0.002). There was also improvement in other symptoms such as urgency and diarrhea. Over the period of follow up, there was no recurrence of anemia and no complications were noted. Conclusion:  These results suggest that argon Plasma Coagulation is a safe and effective modality in the treatment of chronic radiation proctopathy. © 2004 Blackwell Publishing Asia Pty Ltd

  • Argon Plasma Coagulation as first-line treatment for chronic radiation proctopathy.
    Journal of Gastroenterology and Hepatology, 2004
    Co-Authors: Shaji Sebastian, Humphrey J. O'connor, Colm O'morain, Martin Buckley
    Abstract:

    Background and Aim:  Chronic radiation proctopathy is a troublesome complication of radiotherapy to the pelvis, for which current treatment modalities are unsatisfactory. The present prospective study was designed to determine the usefulness and safety of argon Plasma Coagulation in the management of chronic radiation proctopathy. Methods:  Twenty-five consecutive patients (M:F 24:1, mean age: 69 years) with radiation proctopathy were prospectively included. All patients received argon Plasma Coagulation by a standard protocol. Response to treatment was assessed by symptom response, bleeding severity score, hematological parameters and transfusion requirements over a median 14-month follow up. Results:  Patients received a median of one treatment session with argon Plasma Coagulation. There was significant improvement in rectal bleeding in all patients, with complete cessation of bleeding in 21 (81%) of the patients. The median bleeding severity score fell from 3 to 0 (P 

Shaji Sebastian - One of the best experts on this subject based on the ideXlab platform.

  • argon Plasma Coagulation as first line treatment for chronic radiation proctopathy
    Journal of Gastroenterology and Hepatology, 2004
    Co-Authors: Shaji Sebastian, Humphrey J Oconnor, C Omorain, Martin Buckley
    Abstract:

    Background and Aim:  Chronic radiation proctopathy is a troublesome complication of radiotherapy to the pelvis, for which current treatment modalities are unsatisfactory. The present prospective study was designed to determine the usefulness and safety of argon Plasma Coagulation in the management of chronic radiation proctopathy. Methods:  Twenty-five consecutive patients (M:F 24:1, mean age: 69 years) with radiation proctopathy were prospectively included. All patients received argon Plasma Coagulation by a standard protocol. Response to treatment was assessed by symptom response, bleeding severity score, hematological parameters and transfusion requirements over a median 14-month follow up. Results:  Patients received a median of one treatment session with argon Plasma Coagulation. There was significant improvement in rectal bleeding in all patients, with complete cessation of bleeding in 21 (81%) of the patients. The median bleeding severity score fell from 3 to 0 (P < 0.0005). The mean hemoglobin level rose from 10.05 ± 2.21 g/dL before treatment to 12.44 ± 1.09 g/dL at 6 months following treatment (P < 0.002). There was also improvement in other symptoms such as urgency and diarrhea. Over the period of follow up, there was no recurrence of anemia and no complications were noted. Conclusion:  These results suggest that argon Plasma Coagulation is a safe and effective modality in the treatment of chronic radiation proctopathy. © 2004 Blackwell Publishing Asia Pty Ltd

  • Argon Plasma Coagulation as first-line treatment for chronic radiation proctopathy.
    Journal of Gastroenterology and Hepatology, 2004
    Co-Authors: Shaji Sebastian, Humphrey J. O'connor, Colm O'morain, Martin Buckley
    Abstract:

    Background and Aim:  Chronic radiation proctopathy is a troublesome complication of radiotherapy to the pelvis, for which current treatment modalities are unsatisfactory. The present prospective study was designed to determine the usefulness and safety of argon Plasma Coagulation in the management of chronic radiation proctopathy. Methods:  Twenty-five consecutive patients (M:F 24:1, mean age: 69 years) with radiation proctopathy were prospectively included. All patients received argon Plasma Coagulation by a standard protocol. Response to treatment was assessed by symptom response, bleeding severity score, hematological parameters and transfusion requirements over a median 14-month follow up. Results:  Patients received a median of one treatment session with argon Plasma Coagulation. There was significant improvement in rectal bleeding in all patients, with complete cessation of bleeding in 21 (81%) of the patients. The median bleeding severity score fell from 3 to 0 (P 

Matthias Pross - One of the best experts on this subject based on the ideXlab platform.

  • Endoscopic treatment of benign gastrointestinal anastomotic strictures using argon Plasma Coagulation in combination with diathermy
    Surgical Endoscopy And Other Interventional Techniques, 2003
    Co-Authors: D. Schubert, R. Kuhn, H. Lippert, Matthias Pross
    Abstract:

    Background: Initially, treatment for anastomotic strictures was surgical. Currently. however, endoscopic techniques are preferred. This study aimed to investigate the efficiency and safety of endoscopic treatment using argon Plasma Coagulation in combination with diathermy. Methods: From 1995 to 2000, 49 patients with postsurgical anastomotic strictures of the esophagus or colon were referred for endoscopic treatment. In all cases, radiologic and endoscopic examination showed membranous or short strictures (diameter, 3–8 mm). Under direct endoscopic control, the scar tissue at the anastomotic line was incised radially with a polypectomy snare. The scar tissue between the incisions then was reduced carefully by argon Plasma Coagulation. Results: All 49 patients were treated successfully with this combined endoscopic technique. Only for four patients was more than one endoscopic session (mean, 3.5; range, 2–6) needed to guarantee long-term success. No complications were encountered. Conclusions: Endoscopic argon Plasma Coagulation in combination with diathermy is a safe and effective technique for the treatment of short postsurgical gastrointestinal anastomotic strictures.

C Omorain - One of the best experts on this subject based on the ideXlab platform.

  • argon Plasma Coagulation as first line treatment for chronic radiation proctopathy
    Journal of Gastroenterology and Hepatology, 2004
    Co-Authors: Shaji Sebastian, Humphrey J Oconnor, C Omorain, Martin Buckley
    Abstract:

    Background and Aim:  Chronic radiation proctopathy is a troublesome complication of radiotherapy to the pelvis, for which current treatment modalities are unsatisfactory. The present prospective study was designed to determine the usefulness and safety of argon Plasma Coagulation in the management of chronic radiation proctopathy. Methods:  Twenty-five consecutive patients (M:F 24:1, mean age: 69 years) with radiation proctopathy were prospectively included. All patients received argon Plasma Coagulation by a standard protocol. Response to treatment was assessed by symptom response, bleeding severity score, hematological parameters and transfusion requirements over a median 14-month follow up. Results:  Patients received a median of one treatment session with argon Plasma Coagulation. There was significant improvement in rectal bleeding in all patients, with complete cessation of bleeding in 21 (81%) of the patients. The median bleeding severity score fell from 3 to 0 (P < 0.0005). The mean hemoglobin level rose from 10.05 ± 2.21 g/dL before treatment to 12.44 ± 1.09 g/dL at 6 months following treatment (P < 0.002). There was also improvement in other symptoms such as urgency and diarrhea. Over the period of follow up, there was no recurrence of anemia and no complications were noted. Conclusion:  These results suggest that argon Plasma Coagulation is a safe and effective modality in the treatment of chronic radiation proctopathy. © 2004 Blackwell Publishing Asia Pty Ltd

Humphrey J Oconnor - One of the best experts on this subject based on the ideXlab platform.

  • argon Plasma Coagulation as first line treatment for chronic radiation proctopathy
    Journal of Gastroenterology and Hepatology, 2004
    Co-Authors: Shaji Sebastian, Humphrey J Oconnor, C Omorain, Martin Buckley
    Abstract:

    Background and Aim:  Chronic radiation proctopathy is a troublesome complication of radiotherapy to the pelvis, for which current treatment modalities are unsatisfactory. The present prospective study was designed to determine the usefulness and safety of argon Plasma Coagulation in the management of chronic radiation proctopathy. Methods:  Twenty-five consecutive patients (M:F 24:1, mean age: 69 years) with radiation proctopathy were prospectively included. All patients received argon Plasma Coagulation by a standard protocol. Response to treatment was assessed by symptom response, bleeding severity score, hematological parameters and transfusion requirements over a median 14-month follow up. Results:  Patients received a median of one treatment session with argon Plasma Coagulation. There was significant improvement in rectal bleeding in all patients, with complete cessation of bleeding in 21 (81%) of the patients. The median bleeding severity score fell from 3 to 0 (P < 0.0005). The mean hemoglobin level rose from 10.05 ± 2.21 g/dL before treatment to 12.44 ± 1.09 g/dL at 6 months following treatment (P < 0.002). There was also improvement in other symptoms such as urgency and diarrhea. Over the period of follow up, there was no recurrence of anemia and no complications were noted. Conclusion:  These results suggest that argon Plasma Coagulation is a safe and effective modality in the treatment of chronic radiation proctopathy. © 2004 Blackwell Publishing Asia Pty Ltd