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Tin Aung - One of the best experts on this subject based on the ideXlab platform.
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Plateau Iris distribution across anterior segment optical coherence tomography defined subgroups of subjects with primary angle closure glaucoma
Investigative Ophthalmology & Visual Science, 2017Co-Authors: Sushma Verma, Monisha E Nongpiur, Hnin Hnin Oo, Eray Atalay, Tina T Wong, Shamira A Perera, Tin AungAbstract:Purpose: We previously identified three distinct subgroups of patients with primary angle closure glaucoma (PACG) based on anterior segment optical coherence tomography (ASOCT) imaging. Group 1 was characterized by a large Iris area with deepest anterior chambers, group 2 by a large lens vault (LV) and shallow anterior chamber depth (ACD), and group 3 displayed intermediate values across Iris area, LV, and ACD. The purpose of the present study was to determine the distribution of Plateau Iris in these subgroups using ultrasound biomicroscopy (UBM) features. Methods: UBM images of the 210 subjects who were previously enrolled for the ASOCT subgrouping analysis and had undergone laser peripheral iridotomy were assessed and graded by a single glaucoma fellowship trained clinician. Plateau Iris was defined as the presence of all the following UBM criteria in at least two quadrants: anteriorly directed ciliary body, absent ciliary sulcus, Iris angulation, flat Iris plane, and iridoangle touch. Results: Of 210 subjects, 23 were excluded due to poor-quality images. Based on standardized UBM criteria, the overall prevalence of Plateau Iris was 36.9% (n = 187). The proportion of Plateau Iris was similar across the three groups (subgroup 1:35.4% (n = 29); subgroup 2:39.0% (n = 32); subgroup 3:34.8% (n = 8), P = 0.87). On multiple logistic regression analysis, Iris thickness at 750 μm from the scleral spur (IT750) was the only variable associated with Plateau Iris (odds ratio: 1.5/100 μm increase in Iris thickness [IT], P = 0.04). Conclusions: The proportion of Plateau Iris was similar across the three ASOCT-based PACG subgroups and more than one-third of subjects with PACG were diagnosed with Plateau Iris based on standardized UBM criteria. In addition, we noted that eyes with increased peripheral IT have an increased likelihood of Plateau Iris.
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Plateau Iris Distribution Across Anterior Segment Optical Coherence Tomography Defined Subgroups of Subjects With Primary Angle Closure Glaucoma
Investigative Ophthalmology & Visual Science, 2017Co-Authors: Sushma Verma, Monisha E Nongpiur, Hnin Hnin Oo, Eray Atalay, Tina T Wong, Shamira A Perera, Tin AungAbstract:We previously identified three distinct subgroups of patients with primary angle closure glaucoma (PACG) based on anterior segment optical coherence tomography (ASOCT) imaging. Group 1 was characterized by a large Iris area with deepest anterior chambers, group 2 by a large lens vault (LV) and shallow anterior chamber depth (ACD), and group 3 displayed intermediate values across Iris area, LV, and ACD. The purpose of the present study was to determine the distribution of Plateau Iris in these subgroups using ultrasound biomicroscopy (UBM) features. UBM images of the 210 subjects who were previously enrolled for the ASOCT subgrouping analysis and had undergone laser peripheral iridotomy were assessed and graded by a single glaucoma fellowship trained clinician. Plateau Iris was defined as the presence of all the following UBM criteria in at least two quadrants: anteriorly directed ciliary body, absent ciliary sulcus, Iris angulation, flat Iris plane, and iridoangle touch. Of 210 subjects, 23 were excluded due to poor-quality images. Based on standardized UBM criteria, the overall prevalence of Plateau Iris was 36.9% (n = 187). The proportion of Plateau Iris was similar across the three groups (subgroup 1:35.4% (n = 29); subgroup 2:39.0% (n = 32); subgroup 3:34.8% (n = 8), P = 0.87). On multiple logistic regression analysis, Iris thickness at 750 μm from the scleral spur (IT750) was the only variable associated with Plateau Iris (odds ratio: 1.5/100 μm increase in Iris thickness [IT], P = 0.04). The proportion of Plateau Iris was similar across the three ASOCT-based PACG subgroups and more than one-third of subjects with PACG were diagnosed with Plateau Iris based on standardized UBM criteria. In addition, we noted that eyes with increased peripheral IT have an increased likelihood of Plateau Iris.
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Plateau Iris in asian subjects with primary angle closure glaucoma
Archives of Ophthalmology, 2009Co-Authors: Rajesh S Kumar, Visanee Tantisevi, Melissa H Y Wong, Kobkuea Laohapojanart, Orathai Chansanti, Desmond Quek, Lakshmana S Mohanram, Prin Rojanapongpun, Tin AungAbstract:Objective To determine the prevalence of Plateau Iris in Asian eyes with primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM). Methods In this cross-sectional observational study, subjects older than 40 years with PACG who had a patent laser peripheral iridotomy underwent UBM in 1 eye. Ultrasound biomicroscopy images were qualitatively analyzed using standardized criteria. Plateau Iris in a quadrant was defined by anteriorly directed ciliary body, absent ciliary sulcus, steep Iris root from its point of insertion followed by a downward angulation, flat Iris plane, and irido-angle contact. At least 2 quadrants had to fulfill these UBM criteria for an eye to be classified as having Plateau Iris. Results One hundred eleven subjects (70 from Singapore, 41 from Thailand) with PACG were recruited. The mean (SD) age was 65.6 (8.1) years, and 63.9% were female. Based on standardized UBM criteria, Plateau Iris was found in 36 of 111 eyes (32.4%; 95% confidence interval, 24.4%-41.6%). In these 36 eyes, quadrant-wise analysis showed 66.7% had Plateau Iris in 2 quadrants; 22.2%, in 3 quadrants; and 11.1%, in all quadrants. Conclusions About 30% of PACG eyes with a patent laser peripheral iridotomy were found to have Plateau Iris on UBM, highlighting the importance of non–pupil block mechanisms in Asian individuals.
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prevalence of Plateau Iris in primary angle closure suspects an ultrasound biomicroscopy study
Ophthalmology, 2008Co-Authors: Rajesh S Kumar, Mani Baskaran, Paul T K Chew, David S Friedman, Swati Handa, Raghavan Lavanya, Lisandro M Sakata, Hon Tym Wong, Tin AungAbstract:Purpose To determine the prevalence of Plateau Iris in a cohort of primary angle closure suspects (PACSs) using ultrasound biomicroscopy (UBM). Design Cross-sectional observational study. Participants Subjects over the age of 50 years diagnosed as PACSs. Intervention Subjects were randomized to undergo laser peripheral iridotomy (LPI) in one eye. Ultrasound biomicroscopy was performed before and a week after LPI. Main Outcome Measures Ultrasound biomicroscopy images were qualitatively assessed using standardized criteria. Plateau Iris was defined in a quadrant by the presence of an anteriorly directed ciliary body, an absent ciliary sulcus, a steep Iris root from its point of insertion followed by a downward angulation from the corneoscleral wall, presence of a central flat Iris plane, and irido-angle contact. At least 2 quadrants had to fulfil the above criteria for an eye to be defined as Plateau Iris. Results Two hundred five subjects were enrolled; UBM images of 167 subjects were available for analysis. Plateau Iris was found in 54 of 167 (32.3%) PACS eyes after LPI. Quadrantwise analysis showed that 44 of 167 (26.3%) eyes had Plateau Iris in 1 quadrant, 36 (21.5%) in 2 quadrants, 16 (9.5%) in 3 quadrants, and 2 (1.2%) in all 4 quadrants. Plateau Iris was most commonly observed in the superior and inferior quadrants. Conclusions Using standardized UBM criteria, Plateau Iris was found in about a third of PACS eyes after LPI. Prospective longitudinal studies are required to determine the clinical significance of this finding for the management of PACSs.
Robert Ritch - One of the best experts on this subject based on the ideXlab platform.
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Long-term success of argon laser peripheral iridoplasty in the management of Plateau Iris syndrome.
Ophthalmology, 2020Co-Authors: Robert Ritch, Clement C Y ThamAbstract:Abstract Objective To document the long-term effect of argon laser peripheral iridoplasty (ALPI) in eyes with Plateau Iris syndrome. Design Retrospective, noncomparative, interventional case series. Setting New York Eye and Ear Infirmary. Methods The charts of all patients with Plateau Iris syndrome treated with ALPI from 1982 to 1991 and subsequently followed for 6 or more years were retrospectively reviewed. Patients with lens-related mechanisms contributing to angle closure (e.g., phacomorphic or malignant glaucoma) were excluded. Main outcome measures Necessity for repeat ALPI and/or any additional means of intervention. Results A total of 26 ALPI procedures were performed in 23 eyes of 14 patients (4 men, 10 women). The mean age was 61±8.7 years. The mean follow-up was 78.9±8.0 months (range, 72–188 months). The angle in 20 of 23 (87.0%) eyes remained open throughout the entire follow-up period after only 1 treatment with ALPI. In 3 eyes, there was gradual reclosure of the angle 5 to 9 years after initial ALPI, but they were readily reopened and maintained open by a single repeat treatment. No filtration surgery was necessary in any eye during follow-up. Conclusions ALPI is highly effective in eliminating residual appositional closure after laser iridotomy caused by Plateau Iris syndrome. The effect is maintained for years, although a small proportion of patients might require retreatment.
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Laser surgery for angle closure glaucoma
Seminars in Ophthalmology, 2020Co-Authors: Jeffrey M Liebmann, Robert RitchAbstract:The angle closure glaucomas are defined by iridotrabecular contact, trabecular dysfunction, and elevated intraocular pressure (IOP). Laser iridotomy successfully eliminates the relative pupillary block component of the angle closure process, regardless of whether the underlying angle closure is related primarily to pupillary block or another mechanism. For those eyes with angle closure originating at an anatomic level posterior to the Iris, such as Plateau Iris, lens-induced angle closure, or posterior segment processes, argon laser peripheral iridoplasty is often useful to further open the angle. The purpose of this article is to review the indications and techniques for laser iridotomy and laser iridoplasty in clinical practice.
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Is preoperative ciliary body and Iris anatomical configuration a predictor of malignant glaucoma development
Clinical and Experimental Ophthalmology, 2013Co-Authors: Tiago S. Prata, Jeffrey M Liebmann, Syril Dorairaj, Carlos Gv De Moraes, Siddhart Mehta, Zaher Sbeity, Celso Tello, Robert RitchAbstract:Background To investigate anatomical configuration of ciliary body and Iris using ultrasound biomicroscopy as a predictor of malignant glaucoma development. Design Retrospective study in a tertiary care hospital. Participants Cohort of 31 consecutive patients diagnosed with post-surgical malignant glaucoma. Methods Anterior chamber angle, Iris and ciliary body configuration of involved eyes that had ultrasound biomicroscopy evaluation prior to the malignant glaucoma onset were evaluated. In cases with no presurgical ultrasound biomicroscopy exam of the involved eye, images from the fellow eye (imaged within 6 months) were analysed. Main Outcome Measures Qualitative parameters. Results Thirty-one eyes (31 patients) had confirmed malignant glaucoma between 1996 and 2008. Most patients were women (65%) and had an anatomical narrow angle or angle-closure glaucoma (77%). Mean intraocular pressure at diagnosis was 30.4 ± 13.5 mmHg. The most common operation was trabeculectomy with mitomycin C (55%, 17/31 eyes), combined (3/17) or not (14/17) with cataract extraction and intraocular lens implantation. Among these 31 cases, we were able to evaluate the ultrasound biomicroscopy images of 13 patients (13 eyes) including involved eyes imaged prior to the malignant glaucoma onset or eligible fellow eyes. A narrow angle with or without iridotrabecular contact was found in all eyes. A large and/or anteriorly positioned ciliary body associated with an Iris root angulating forward and centrally, revealing a Plateau Iris configuration, was noticed in 85% (11/13) of these eyes. Conclusion Identification of Plateau Iris configuration by ultrasound biomicroscopy should be considered as a possible predictor of post-operative malignant glaucoma development.
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Argon laser peripheral iridoplasty (ALPI): an update.
Survey of Ophthalmology, 2007Co-Authors: Robert Ritch, Clement C Y ThamAbstract:Argon laser peripheral iridoplasty is a useful procedure to eliminate appositional angle closure resulting from mechanisms other than pupillary block. For those eyes with angle closure originating at an anatomic level posterior to the Iris, such as Plateau Iris, lens-induced angle closure, or posterior segment processes (malignant glaucoma, central retinal vein occlusion, etc.), laser iridotomy by itself may be insufficient to treat the underlying disease mechanism. Argon laser peripheral iridoplasty is often useful in these cases to further open the angle. It can be used to break an acute attack of angle-closure glaucoma and relieve appositional angle closure secondary to Plateau Iris syndrome, or lens-related angle closure, and to widen the angle prior to argon laser trabeculoplasty. Peripheral location of long-duration, low-power, large spot size laser burns is essential for optimal success.
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long term success of argon laser peripheral iridoplasty in the management of Plateau Iris syndrome
Ophthalmology, 2004Co-Authors: Robert Ritch, Clement C Y ThamAbstract:OBJECTIVE: To document the long-term effect of argon laser peripheral iridoplasty (ALPI) in eyes with Plateau Iris syndrome. DESIGN: Retrospective, noncomparative, interventional case series. SETTING: New York Eye and Ear Infirmary. METHODS: The charts of all patients with Plateau Iris syndrome treated with ALPI from 1982 to 1991 and subsequently followed for 6 or more years were retrospectively reviewed. Patients with lens-related mechanisms contributing to angle closure (e.g., phacomorphic or malignant glaucoma) were excluded. MAIN OUTCOME MEASURES: Necessity for repeat ALPI and/or any additional means of intervention. RESULTS: A total of 26 ALPI procedures were performed in 23 eyes of 14 patients (4 men, 10 women). The mean age was 61+/-8.7 years. The mean follow-up was 78.9+/-8.0 months (range, 72-188 months). The angle in 20 of 23 (87.0%) eyes remained open throughout the entire follow-up period after only 1 treatment with ALPI. In 3 eyes, there was gradual reclosure of the angle 5 to 9 years after initial ALPI, but they were readily reopened and maintained open by a single repeat treatment. No filtration surgery was necessary in any eye during follow-up. CONCLUSIONS: ALPI is highly effective in eliminating residual appositional closure after laser iridotomy caused by Plateau Iris syndrome. The effect is maintained for years, although a small proportion of patients might require retreatment.
Olivia Abitbol - One of the best experts on this subject based on the ideXlab platform.
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Increased choroidal thickness in primary angle closure measured by swept-source optical coherence tomography in Caucasian population
International Ophthalmology, 2020Co-Authors: Diem-trang Nguyen, Audrey Giocanti-auregan, Nassima Benhatchi, Nicolas Greliche, Hélène Beaussier, Pierre Sustronck, Sirine Hammoud, Marie-nathalie Jeanteur, Gilles Kretz, Olivia AbitbolAbstract:Purpose A role of the choroid has been suggested in the pathophysiology of angle closure. We assessed the choroidal thickness (CT) in Caucasian patients with primary angle closure (PAC) and in a subgroup of patients with Plateau Iris using swept-source optical coherence tomography (SS-OCT) compared to normal eyes. Methods This prospective cohort study in a hospital-based population in a tertiary center compared consecutive patients with PAC to healthy controls. A subgroup analysis of patients with Plateau Iris was also performed. Choroidal thickness was measured by SS-OCT in the subfoveal area (SFCT) and at 1- and 3-mm eccentricity superiorly, inferiorly, nasally and temporally from the fovea. Results Compared to the 25 eyes of 13 control patients [7 women, mean (SD) age, 56.6 (15.7) years], the 45 eyes of 25 patients with PAC [15 women, mean (SD) age, 55.7 (10.7) years] had a significantly increased SFCT. SFCT was 355.36 μm (SD 85.97) in PAC eyes versus 286.08 μm (SD 98.09) in control eyes ( p = 0.009). The CT was also significantly increased compared to control eyes in other macular areas ( p
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Increased choroidal thickness in primary angle closure measured by swept-source optical coherence tomography in Caucasian population.
International Ophthalmology, 2019Co-Authors: Diem-trang Nguyen, Audrey Giocanti-auregan, Nassima Benhatchi, Nicolas Greliche, Hélène Beaussier, Pierre Sustronck, Sirine Hammoud, Marie-nathalie Jeanteur, Kretz G, Olivia AbitbolAbstract:Purpose: A role of the choroid has been suggested in the pathophysiology of angle closure. We assessed the choroidal thickness (CT) in Caucasian patients with primary angle closure (PAC) and in a subgroup of patients with Plateau Iris using swept-source optical coherence tomography (SS-OCT) compared to normal eyes. Methods: This prospective cohort study in a hospital-based population in a tertiary center compared consecutive patients with PAC to healthy controls. A subgroup analysis of patients with Plateau Iris was also performed. Choroidal thickness was measured by SS-OCT in the subfoveal area (SFCT) and at 1- and 3-mm eccentricity superiorly, inferiorly, nasally and temporally from the fovea. Results: Compared to the 25 eyes of 13 control patients [7 women, mean (SD) age, 56.6 (15.7) years], the 45 eyes of 25 patients with PAC [15 women, mean (SD) age, 55.7 (10.7) years] had a significantly increased SFCT. SFCT was 355.36 mu m (SD 85.97) in PAC eyes versus 286.08 mu m (SD 98.09) in control eyes (p = 0.009). The CT was also significantly increased compared to control eyes in other macular areas (p < 0.05), except at 3 mm temporal to the fovea. In the Plateau Iris subgroup, a not significant (except 3 mm nasal to the fovea) trend toward an increased CT was observed in all studied macular areas compared to control eyes. Conclusion: In eyes of Caucasian patients with PAC, the CT is increased compared to controls. Increased CT could contribute to the pathophysiology of PAC with a possible choroidal expansion and dysfunction of choroidal ganglion cells.
Nassim Calixto - One of the best experts on this subject based on the ideXlab platform.
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Plateau Iris configuration in eyes with narrow-angle: an ultrasound biomicroscopic study.
Arquivos brasileiros de oftalmologia, 2010Co-Authors: Alberto Diniz Filho, Sebastião Cronemberger, Dollores Martins Ferreira, Rafael Vidal Mérula, Nassim CalixtoAbstract:PURPOSE: To investigate, through ultrasound biomicroscopy images, the presence of Plateau Iris configuration in eyes with narrow-angle from patients with open-angle glaucoma and in eyes with previous acute primary angle-closure and compare the biometric features of eyes with Plateau Iris configuration with those of normal eyes.\n\nMETHODS: Ultrasound biomicroscopic images from 196 patients with open-angle glaucoma and narrow-angle and 32 patients with acute primary angle-closure were retrospectively analyzed. The inclusion and specific criteria for the diagnosis of Plateau Iris configuration was the presence of an anterior positioning of the ciliary processes, supporting the peripheral Iris so that it was parallel to the trabecular meshwork; the Iris root had a steep rise from its insertion point, followed by a downward angulation from the corneoscleral wall; presence of a central flat Iris plane; an absent (complete Plateau Iris configuration) or partially absent (incomplete Plateau Iris configuration) ciliary sulcus. The ultrasound biomicroscopic parameters were compared between complete and incomplete Plateau Iris configuration. The same parameters of both groups were compared with those of normal eyes. The following measurements were performed: anterior chamber depth; angle opening distance at 500 microm from the scleral spur; peripheral Iris thickness at 500 microm from the scleral spur; Iris-ciliary process distance; trabecular-ciliary process distance and angle recess area.\n\nRESULTS: Plateau Iris configuration was found in 33 eyes of 20 (10.2%) out of 196 patients with open-angle glaucoma and narrow-angle and in 4 eyes of 2 (6.3%) out of 32 patients with acute primary angleclosure. Seventeen (77.3%) patients with Plateau Iris configuration were female and 5 (22.7%) male. Twenty-three (62.2%) out of 37 eyes had complete Plateau Iris configuration, and 14 (37.8%) had incomplete Plateau Iris configuration. Complete and incomplete Plateau Iris configuration presented similar biometric features with the exception of the Iris-ciliary process distance. All Plateau Iris configuration eyes showed biometric parameters completely different from those of normal eyes except for peripheral Iris thickness at 500 microm from the scleral spur.\n\nCONCLUSIONS: Plateau Iris configuration was present in 10.2% of patients with open-angle glaucoma and narrow-angle and in 6.3% of patients with acute primary angle-closure. Biometric features were similar in eyes with complete and incomplete Plateau Iris configuration with the exception of Iris-ciliary process distance. Compared to normal eyes, all Plateau Iris configuration eyes showed biometric parameters completely different except for peripheral Iris thickness at 500 microm from the scleral spur.
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comparative biometric study between Plateau Iris configuration and primary open angle glaucoma with narrow angle
Arquivos Brasileiros De Oftalmologia, 2009Co-Authors: Alberto Diniz Filho, Sebastião Cronemberger, Rafael Vidal Merula, Nassim CalixtoAbstract:PURPOSE: To investigate biometrically the differences between Plateau Iris configuration (PIC) eyes and primary open angle glaucoma with narrow angle eyes. METHODS: A comparative study involving a case series with 20 eyes of 11 Plateau Iris configuration patients and 45 eyes of 27 primary open angle glaucoma with narrow angle eyes patients was done. The following measurements were taken: corneal curvature, central corneal thickness, anterior chamber depth, lens thickness (LT), axial length (AL), lens thickness and axial length ratio, lens position (LP) and relative lens position (RLP). RESULTS: The Plateau Iris configuration eyes presented a higher corneal cuvature value than primary open angle glaucoma with narrow angle eyes eyes but not with clinical and statistical difference (P=0.090). The Plateau Iris configuration eyes demonstrated a higher central corneal thickness, with statistical significance, when compared to primary open angle glaucoma with narrow angle eyes (P=0.010). Statistical significant difference between Plateau Iris configuration and primary open angle glaucoma with narrow angle eyes was found in axial length (21.69 ± 0.98 vs. 22.42 ± 0.89; P=0.003). No significant difference was found when anterior chamber depth (2.62 ± 0.23 vs. 2.71 ± 0.31; P=0.078), LT (4.67 ± 0.36 vs. 4.69 ± 0.45; P=0.975), LT/AL (2.16 ± 0.17 vs. 2.10 ± 0.21; P=0.569), LP (4.95 ± 0.25 vs. 5.06 ± 0.34; P=0.164) and RLP (0.23 ± 0.01 vs. 0.22 ± 0.14; P=0.348) were evaluated. CONCLUSION: The eyes with Plateau Iris configuration presented statistical significantly shorter axial length and higher central corneal thickness than primary open angle glaucoma with narrow angle eyes.
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comparative study between Plateau Iris configuration and primary open angle glaucoma with narrow angle using ultrasound biomicroscopy
Investigative Ophthalmology & Visual Science, 2009Co-Authors: Diniz A Filho, Sebastião Cronemberger, Rafael Vidal Merula, Nassim CalixtoAbstract:Abstract Purpose: To compare topologic features between eyes of patients with Plateau Iris configuration (PIC) and eyes of patients with primary open angle glaucoma with narrow angle (POAGNA), and to identify any characteristics that could contribute to clarify the importance of the Plateau Iris component in the mechanism of angle closure. Methods: Twenty eyes of 11 patients with PIC and 45 eyes of 27 patients with POAGNA were prospectively examined by ultrasound biomicroscopy (UBM) under light and dark conditions. All eyes were examined in the superior (SQ) and inferior (IQ) quadrants. Measurements of the following UBM parameters were done and compared between the two groups: anterior chamber depth (ACD); Iris-lens contact distance (ILCD); angle opening distance at 250 µm (AOD250) and 500 µm (AOD500) from the scleral spur; trabecular-ciliary process distance (TCPD); Iris-ciliary process distance (ICPD); Iris thickness measured along the same line as the TCPD (ID1); Iris-zonule distance (IZD); Iris thickness measured 2 mm from the Iris root (ID2); and the maximum Iris thickness near the pupillary edge (ID3). Results: Statistically significant differences between PIC and POAGNA eyes under light and dark examinations were found in ACD, P = 0.003; ILCDSQ, P < 0.001; TCPDSQ light, P = 0.020; TCPDSQ dark, P < 0.001; ICPDSQ, P < 0.001; IZDSQ light, P = 0001; IZDSQ dark, P = 0,021; ILCDIQ, P < 0.001; TCPDIQ, P < 0.001 ICPDIQ, P < 0.001; and IZDIQ light, P < 0.001. The Iris thickness was similar in PIC and POAGNA eyes in both superior and inferior quadrants, except for ID3SQ and ID3IQ both in light and dark conditions that showed statistically significant differences (respectively P = 0.001, P < 0.001, P = 0,021 and P = 0.003). Statistically significant differences between light and dark examinations of PIC eyes were also found in the IZDSQ ( P = 0.033) and ID3SQ ( P = 0.038), and in POAGNA eyes in the ILCDSQ ( P = 0.013), AOD250SQ ( P = 0.034), AOD500SQ ( P = 0.008), ICPDSQ ( P = 0.046), ID1SQ ( P = 0.037), ID3SQ ( P = 0.047), and ILCDIQ ( P < 0.001). Conclusions: Eyes with PIC presented a shallower ACD in comparison to eyes with POAGNA. The ILCD was significantly higher in PIC group. The TCPD, ICPD, IZD and ID3 were significantly higher in POAGNA group. When the illumination conditions were changed from light to dark ILCD, AOD250 and AOD500 decreased in POAGNA group.
Roland Stieger - One of the best experts on this subject based on the ideXlab platform.
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Prevalence of Plateau Iris syndrome in young patients with recurrent angle closure.
Clinical and Experimental Ophthalmology, 2007Co-Authors: Roland Stieger, Christoph Kniestedt, Florian K. P. Sutter, Lucas M. Bachmann, Joerg StuermerAbstract:Background: To assess and describe the prevalence and clinical features associated with Plateau Iris syndrome (PIS) in young individuals with recurrent angle closure despite initial therapy. Methods: Chart review of 137 relatively young individuals (aged
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prevalence of Plateau Iris syndrome in young patients with recurrent angle closure
Clinical and Experimental Ophthalmology, 2007Co-Authors: Roland Stieger, Christoph Kniestedt, Florian K. P. Sutter, Lucas M. Bachmann, Joerg StuermerAbstract:Background: To assess and describe the prevalence and clinical features associated with Plateau Iris syndrome (PIS) in young individuals with recurrent angle closure despite initial therapy. Methods: Chart review of 137 relatively young individuals (aged < 60 years) with symptoms of angle closure between 1995 and 2005. A follow-up period of 36 months after initial presentation was retrospectively analysed. Seventy-six patients with recurrent angle closure symptoms were clinically reviewed using gonioscopy and ultrasound biomicroscopy. Results: Based on chart analysis, 30 of 137 individuals were diagnosed with PIS (22%). After clinical review, 34 additional patients suffered from PIS as the underlying cause for persistent angle closure symptoms. The prevalence of PIS in our patient population with recurrent angle closure symptoms in spite of initial iridotomy or iridectomy was 54%. Conclusion: Among angle closure in young individuals, PIS is not uncommon. The causative mechanism of PIS in young individuals is peripheral Iris block, rather than pupillary block which is more often prevalent in older patients. For proper diagnosis and therapy, ultrasound biomicroscopy and gonioscopy should be performed on every young individual with angle closure symptoms.