The Experts below are selected from a list of 183 Experts worldwide ranked by ideXlab platform

Lin Shao - One of the best experts on this subject based on the ideXlab platform.

  • The value of VATS in treatment of the patients with severe obstructive pulmonary dysfunction
    Hainan Medical Journal, 2002
    Co-Authors: Lin Shao
    Abstract:

    Objectives: To evaluate the feasibility of VATS in treatment of the patients with severe obstructive pulmonary dysfunction.Methods 17 patients with severer obstructive pulmonary dysfunction underwent operations by VATS.Results: Pulmonary wedge resections in 9,pulmonary segmentectomies in 1.bulous ablation in 4,pericardial window in 1,excision of tumor in the posterior mediastinum in 1,pulmonary capacity reduction in 1.Bleeding in the procedure 10～200ml without blood transfusion.2 cases were postoperatively supported by mechanical ventilation(48～68hs).3 patients complicated with arrhythmias,Pleura Effusion,air leak.There was no mortality.All patients were discharge from hospital.Conclusions:VAST is recommended to be the first choice on the patient with severe obstructive pulmonary dysfunction.

Liu Bao-rui - One of the best experts on this subject based on the ideXlab platform.

  • Appropriate dosage of interleukin-2 for tumor infiltrating lymphocyte cultured in self-supernatant of malignant Pleura fluid
    Journal of Medical Postgraduates, 2007
    Co-Authors: Liu Bao-rui
    Abstract:

    Objective:To select an appropriate dosage of IL-2 for tumor infiltrating lymphocyte(TIL).Methods:Isolated by the attachment method we established,TIL was cultivated in self-supernatant of malignant Pleura,with three different concentrations of IL-2,such as 6000u per ml,6000u per ml for the first administration followed by 1000u per ml,or 1000u per ml.The expansion,killing activity and phenotype changes of TIL cultured in different cultures were assessed.Results:As cultured in self-supernatant of malignant Pleura fluid,the concentrations of IL-2,such as 6000u per ml or 6000u per ml for the first administration followed by 1000u per ml seemed benefit for TIL proliferation.Conclusion:6000u per ml of IL-2 for the first administration was very important.It could help TIL to activate and proliferate early.The study described here offers the possibility for TIL cultured in vitro self-supernatant of malignant Pleura fluid in vitro for a short time,and then reinfuse to thorax for further expanding and controlling the malignant Pleura Effusion in the presence of IL-2,and thereby minimizing the risks of contamination.

  • The use of autologous supernatant of malignant Pleura Effusion in culturing human tumor infiltrating lymphocytes in vitro
    Journal of Medical Postgraduates, 2005
    Co-Authors: Liu Bao-rui
    Abstract:

    Objective:To study the effect of autologous supernatant of malignant Pleura Effusion and RPMI1640 with 10% AB+ serum on the culture of tumor infiltrating lymphocytes (TIL) in vitro. Methods:Isolated by the attachment method we established, TIL was cultured in either autologous supernatant of malignant Pleura fluid or RPMI1640 with 10% AB+ serum, and various types of cytokines such as (IL-2,) PHA and antibody against CD3 (OKT3) were added into both cultures. The proliferation as well as the killing activity and the phenotype changes of TIL cultured in the two kinds of cultures were compared. Results:There was no difference in the proliferation or the killing activity in vitro as well as the phenotype changes of TIL between the two kinds of cultures. Conclusion: Autologous supernatant of malignant Pleura fluid could be used as TIL culture medium. The method described here made it possible for TIL to be cultured in vitro for a short time, and then reinfused back to thorax for further expanding and controlling the malignant Pleura Effusion in the presence of IL-2, and it alsominimized the risks of contamination.

Rita Zahara Ibrahim - One of the best experts on this subject based on the ideXlab platform.

  • Experience using of ultrasound guidance Pleural tapping in Pleural Effusion after cardiac surgery in National Cardiac Centre Harapan Kita Hospital. Indonesia (Case Series)
    Critical Ultrasound Journal, 2014
    Co-Authors: Rita Zahara Ibrahim
    Abstract:

    Pleura Effusion in post cardiac surgery is the one of problems in management of cardiac surgery patients. Large amounts of Pleura Effusion may affect the recovery period requiring a longer hospital stay. Early diagnosis and quantification of Pleural Effusion is important to be ideal postoperative adequate treatment. Ultrasound shows better sensitivity and reliability for diagnosis Pleural Effusion than physic diagnostic and X-ray. Ultrasound can be repeated serially at bedside without any radiation risk. Procedure perform under ultrasound guided showed a reduction of complication rate. We report 60 patients with Pleural Effusion after cardiac surgery. We perform tapping of fluid under guiding ultrasound. Before procedure we calculate amount of Pleural Effusion and make decision where site of needle will inserted. Regarding the literature we make intraclavicula line as a guided. Tapping procedure will perform if fluid more than 450 cc. Tapping procedure use abbocate needle no 14 or 16fr. Amount of perithoracosistesis fluid is almost same with fluid prediction of before +/- 50 cc, depend on body weight and size of heart if Pleural Effusion on left thorax. There are not complications after the procedure. Patient experiences were feel convenient and with minimal pain. After procedure patients can complete mobilization and if indication to discharge patients can discharge directly.

Michel Duval - One of the best experts on this subject based on the ideXlab platform.

  • Excess of Veno-Occlusive Disease in a Randomized Clinical Trial on a Higher Trigger for Red Blood Cell Transfusion after Bone Marrow Transplantation: A Canadian Blood and Marrow Transplant Group Trial
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012
    Co-Authors: Nancy Robitaille, Jacques Lacroix, Lubomir Alexandrov, Lucy Clayton, Marion Cortier, Kirk R. Schultz, Henrique Bittencourt, Michel Duval
    Abstract:

    Previous studies have shown that maintaining high hemoglobin levels in patients after chemotherapy reduced the length of neutropenia. Thus, we undertook a randomized, controlled, clinical trial in children undergoing allogeneic bone marrow transplantation after receiving a myeloablative conditioning regimen to compare 2 hemoglobin thresholds as triggers for red blood cell transfusion: 120 g/L in the experimental arm and 70 g/L in the control arm. The Data and Safety Monitoring Board closed the study after enrollment of the sixth patient because 3 patients in the experimental arm contracted veno-occlusive disease, but none in the control arm did (P = .05). Ascites was present in all 3 patients, Pleura Effusion in 2, and portal vein thrombosis in 2. One patient experienced hepatic failure and required treatment with the molecular adsorbent recycling system. Another patient required hemodialysis for renal failure. No major imbalance between groups was seen with regard to risk factors for veno-occlusive disease. Therefore, maintaining the hemoglobin at higher levels should be avoided after hematopoietic stem cell transplantation.

Gary A. Ulaner - One of the best experts on this subject based on the ideXlab platform.

  • Patient Repositioning Reveals a Malignant Pleura Effusion Initially Mistaken as a Bone Metastasis on 18FDG PET/CT.
    Clinical nuclear medicine, 2019
    Co-Authors: Julian Kirchner, Christopher C. Riedl, Gary A. Ulaner
    Abstract:

    A 70-year-old woman with breast cancer underwent F-FDG PET/CT for restaging. An FDG-avid focus corresponding to a rib on CT images was identified and interpreted as suggestive of an osseous metastasis. A PET/CT-guided biopsy was planned with the patient in prone position. Prone images demonstrated the FDG focus "moved" to the anterior chest and corresponding to Pleural fluid. The diagnosis was altered from osseous metastases to Pleural malignancy, and the bone biopsy was not performed. This case not only emphasizes the sensitivity of PET in the detection of malignancy, but also highlights the difficulty localizing small, mobile, FDG-avid foci.