The Experts below are selected from a list of 60 Experts worldwide ranked by ideXlab platform
John A Waldhausen - One of the best experts on this subject based on the ideXlab platform.
-
end to end repair of aortic coarctation using absorbable Polydioxanone Suture
The Annals of Thoracic Surgery, 1991Co-Authors: Juan D Arenas, John L Myers, Marie M Gleason, Alexander Vennos, Barry G Baylen, John A WaldhausenAbstract:Abstract Based on previous laboratory work, we have used Polydioxanone absorbable Suture in a variety of vascular and cardiac repairs in pediatric patients. However, some investigators have expressed concern about the potential for aneurysm formation at the anastomotic site. Between March 1983 and June 1989, 15 patients (7 male, 8 female) aged 2.5 months to 9.2 years (mean, 3.7 years) had resection of coarctation of the aorta and end-to-end anastomosis with Polydioxanone absorbable Suture. Thirteen patients have returned for routine postoperative evaluation, the follow-up time ranging from 11 to 49 months (mean, 23 months). Noninvasive two-dimensional, pulsed-wave Doppler and color echocardiography and magnetic resonance imaging studies demonstrated good anatomical repair and no anastomotic aneurysm formation or residual coarctation of the aorta in any patient after end-to-end anastomosis with Polydioxanone. In summary, this intermediate follow-up study has revealed no vascular complications related to the repair of coarctation with absorbable Polydioxanone Suture.
-
results of aortic anastomoses made under tension using Polydioxanone Suture
The Annals of Thoracic Surgery, 1990Co-Authors: Randy S Haluck, Wayne E Richenbacher, John L Myers, Cynthia A Miller, John A WaldhausenAbstract:Abstract After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem. Use of absorbable Sutures has been shown to be superior to use of nonabsorbable Sutures in allowing growth of an anastomotic site along with the individual. Some concern has been raised, however, about the potential for aneurysm formation at the site of anastomosis when absorbable Sutures are used. This study was undertaken to observe the effects of longitudinal tension on anastomoses made with absorbable Polydioxanone Suture in growing animals. Six piglets (aged 3 to 4 weeks) underwent a 1-cm resection of the infrarenal aorta and reanastomosis with Polydioxanone Suture. One animal died prematurely of respiratory illness. The 5 remaining animals were killed after 6 months. The excised aortas demonstrated no stenosis, no dilatation, and no bursttest failure to 250 mm Hg. Histological examination showed disrupted elastic laminae without thinning of aortic wall in all samples of aorta. We conclude that Polydioxanone Suture is a suitable Suture material for vascular anastomoses made under tension where growth of the anastomotic site is expected.
John L Myers - One of the best experts on this subject based on the ideXlab platform.
-
end to end repair of aortic coarctation using absorbable Polydioxanone Suture
The Annals of Thoracic Surgery, 1991Co-Authors: Juan D Arenas, John L Myers, Marie M Gleason, Alexander Vennos, Barry G Baylen, John A WaldhausenAbstract:Abstract Based on previous laboratory work, we have used Polydioxanone absorbable Suture in a variety of vascular and cardiac repairs in pediatric patients. However, some investigators have expressed concern about the potential for aneurysm formation at the anastomotic site. Between March 1983 and June 1989, 15 patients (7 male, 8 female) aged 2.5 months to 9.2 years (mean, 3.7 years) had resection of coarctation of the aorta and end-to-end anastomosis with Polydioxanone absorbable Suture. Thirteen patients have returned for routine postoperative evaluation, the follow-up time ranging from 11 to 49 months (mean, 23 months). Noninvasive two-dimensional, pulsed-wave Doppler and color echocardiography and magnetic resonance imaging studies demonstrated good anatomical repair and no anastomotic aneurysm formation or residual coarctation of the aorta in any patient after end-to-end anastomosis with Polydioxanone. In summary, this intermediate follow-up study has revealed no vascular complications related to the repair of coarctation with absorbable Polydioxanone Suture.
-
results of aortic anastomoses made under tension using Polydioxanone Suture
The Annals of Thoracic Surgery, 1990Co-Authors: Randy S Haluck, Wayne E Richenbacher, John L Myers, Cynthia A Miller, John A WaldhausenAbstract:Abstract After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem. Use of absorbable Sutures has been shown to be superior to use of nonabsorbable Sutures in allowing growth of an anastomotic site along with the individual. Some concern has been raised, however, about the potential for aneurysm formation at the site of anastomosis when absorbable Sutures are used. This study was undertaken to observe the effects of longitudinal tension on anastomoses made with absorbable Polydioxanone Suture in growing animals. Six piglets (aged 3 to 4 weeks) underwent a 1-cm resection of the infrarenal aorta and reanastomosis with Polydioxanone Suture. One animal died prematurely of respiratory illness. The 5 remaining animals were killed after 6 months. The excised aortas demonstrated no stenosis, no dilatation, and no bursttest failure to 250 mm Hg. Histological examination showed disrupted elastic laminae without thinning of aortic wall in all samples of aorta. We conclude that Polydioxanone Suture is a suitable Suture material for vascular anastomoses made under tension where growth of the anastomotic site is expected.
Kiran H Shankar - One of the best experts on this subject based on the ideXlab platform.
-
a comparative study of outcome of the absorbable Suture Polydioxanone and nonabsorbable Suture polypropylene in laparotomy wound closure
International Journal of Research in Medical Sciences, 2016Co-Authors: Kiran H ShankarAbstract:Background: Abdominal wound closure is one of the common operations for a general surgeon. Prevention of complications is important to reduce post-operative morbidity and mortality. Post-operative wound pain, wound infection, wound dehiscence, Suture sinus formation; palpable knots and incisional hernia are the parameters are to be studied. Therefore, the present study was undertaken to compare Polydioxanone and polypropylene Suture material for abdominal fascial closure regarding morbidity in terms of post-operative wound complications. Methods: Patients admitted in the department of surgery, who undergo laparotomy operations, with midline abdominal incisions were included in the study. The recruited subjects were divided into Group-A, whom abdominal incisions are closed with non-absorbable Suture material polypropylene and Group-B whom abdominal incisions are closed with absorbable Suture material Polydioxanone. Data was expressed as percentages. Results: The incidence of wound pain was observed in all the patients in both immediate and delayed post-operative period in the polypropylene Suture material compared to Polydioxanone. The incidence of wound infection was higher in polypropylene (24%) compared to PDS (2%). There were 4% cases of wound dehiscence in the present study. The incidence of Suture sinus formation was higher in the polypropylene Suture material (9%) compared to the Polydioxanone Suture material (2%) in the delayed postoperative period. The incidence of palpable knots was higher in the polypropylene Suture material (23%) compared to the Polydioxanone Suture material. No cases of incisional hernia were reported with Polydioxanone Suture material. Conclusions: The overall morbidity from abdominal closure was considerably reduced in the Polydioxanone group. We encountered reduction in wound complications like burst abdomen, wound infection, wound pain, Suture sinus formation, palpable knots and incisional hernia. Therefore, Polydioxanone can be employed rewardingly in emergency situations where closure can be carried out safely and rapidly.
Peter F Lawrence - One of the best experts on this subject based on the ideXlab platform.
-
initial evaluation of absorbable Polydioxanone Suture for peripheral vascular surgery
Journal of Vascular Surgery, 1991Co-Authors: Steven W Merrell, Peter F LawrenceAbstract:Abstract The long-term integrity of an autogenous vascular anastomosis is primarily dependent on the strength of tissue healing; therefore permanent mechanical support of an autogenous anastomosis with Sutures is unnecessary. In this study we evaluated monofilament absorbable Polydioxanone as an alternative to polypropylene for suturing autogenous vascular tissue during adult peripheral vascular operations. We used Polydioxanone Suture for 21 vascular procedures in 20 patients. We evaluated Suture handling characteristics during operation and then followed patients with clinical assessments and serial duplex scans to monitor for pseudoaneurysms, anastomotic narrowing, and vessel patency. Indications for surgery included limb salvage (67%), dialysis access (23%), traumatic arteriovenous fistula and claudication (5% each). The operative procedures included infrainguinal bypass (57%), arteriovenous fistula formation (24%), thromboembolectomy (14%), and arteriovenous fistula repair (5%). Polydioxanone Sutures were placed in 39 separate test sites (35 arterial, 4 venous). No deaths occurred during operation. Polydioxanone Suture was found to have handling characteristics similar to polypropylene. During mean patient follow-up of 7.2 ± 0.6 months, we found no cases of anastomotic narrowing or pseudoaneurysms. Actuarial test site patency at 1,3, and 6 months was 97%, 97%, and 86%, respectively. Polydioxanone Suture has handling properties that are acceptable for use in vascular applications, and it provides adequate mechanical support for Sutured vessels to heal. A randomized trial comparing Polydioxanone with polypropylene Suture will be necessary to determine whether the lack of permanent foreign material in vascular anastomoses can improve long-term patency. (J VASC SURG 1991;14:452-9.)
Juan D Arenas - One of the best experts on this subject based on the ideXlab platform.
-
end to end repair of aortic coarctation using absorbable Polydioxanone Suture
The Annals of Thoracic Surgery, 1991Co-Authors: Juan D Arenas, John L Myers, Marie M Gleason, Alexander Vennos, Barry G Baylen, John A WaldhausenAbstract:Abstract Based on previous laboratory work, we have used Polydioxanone absorbable Suture in a variety of vascular and cardiac repairs in pediatric patients. However, some investigators have expressed concern about the potential for aneurysm formation at the anastomotic site. Between March 1983 and June 1989, 15 patients (7 male, 8 female) aged 2.5 months to 9.2 years (mean, 3.7 years) had resection of coarctation of the aorta and end-to-end anastomosis with Polydioxanone absorbable Suture. Thirteen patients have returned for routine postoperative evaluation, the follow-up time ranging from 11 to 49 months (mean, 23 months). Noninvasive two-dimensional, pulsed-wave Doppler and color echocardiography and magnetic resonance imaging studies demonstrated good anatomical repair and no anastomotic aneurysm formation or residual coarctation of the aorta in any patient after end-to-end anastomosis with Polydioxanone. In summary, this intermediate follow-up study has revealed no vascular complications related to the repair of coarctation with absorbable Polydioxanone Suture.