The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform

C. Oehr - One of the best experts on this subject based on the ideXlab platform.

  • Ultrathin antibacterial polyammonium coatings on Polymer Surfaces
    Surface & Coatings Technology, 2003
    Co-Authors: J. Thome, A. Holländer, W. Jaeger, I. Trick, C. Oehr
    Abstract:

    Abstract We have developed novel antibacterial coatings from innocuous polyammonium compounds which are chemically coupled to a Polymer Surface. For immobilization we used two strategies: In the first strategy, the Polymer Surface is plasma activated to generate radicals. Then antibacterial monomers, such as diallyldimethylammonium chloride (DADMAC) are grafted to the Surface by a radical Polymerization. In the second strategy, the Polymer Surface is plasma treated to create oxygen functionalities. Antibacterial coPolymers, such as DADMAC coPolymers, are coupled to the activated Surface. Microbiological data prove that the DADMAC coPolymers reduce the settlement of bacteria such as Micrococcus luteus (gram positive) and Escherichia coli (gram negative) by a factor of 10 5 –10 6 . The layers were characterized by X-ray photoelectron spectroscopy (XPS) and contact angle measurements. The extremely thin coatings of only 2–3 nanometers thickness do not change the material properties of the substrate.

  • Ultrathin antibacterial polyammonium coatings on Polymer Surfaces
    Surface and Coatings Technology, 2003
    Co-Authors: J. Thome, A. Holländer, W. Jaeger, I. Trick, C. Oehr
    Abstract:

    We have developed novel antibacterial coatings from innocuous polyammonium compounds which are chemically coupled to a Polymer Surface. For immobilization we used two strategies: In the first strategy, the Polymer Surface is plasma activated to generate radicals. Then antibacterial monomers, such as diallyldimethylammonium chloride (DADMAC) are grafted to the Surface by a radical Polymerization. In the second strategy, the Polymer Surface is plasma treated to create oxygen functionalities. Antibacterial coPolymers, such as DADMAC coPolymers, are coupled to the activated Surface. Microbiological data prove that the DADMAC coPolymers reduce the settlement of bacteria such as Micrococcus luteus (gram positive) and Escherichia coli (gram negative) by a factor of 10(exp 5)-10(exp 6). The layers were characterized by X-ray photoelectron spectroscopy (XPS) and contact angle measurements. The extremely thin coatings of only 2-3 nanometers thickness do not change the material properties of the substrate

Taolei Sun - One of the best experts on this subject based on the ideXlab platform.

  • Sialic acid-triggered macroscopic properties switching on a smart Polymer Surface
    Applied Surface Science, 2018
    Co-Authors: Yuting Xiong, Guangyan Qing, Hongxi Wang, Taolei Sun
    Abstract:

    Abstract Constructing smart Surfaces with responsive Polymers capable of dynamically and reversibly changing their chemical and physical properties by responding to the recognition of biomolecules remains a challenging task. And, the key to achieving this purpose relies on the design of Polymers to precisely interact with the target molecule and successfully transform the interaction signal into tunable macroscopic properties, further achieve special bio-functions. Herein, inspired by carbohydrate–carbohydrate interaction (CCI) in life system, we developed a three-component coPolymer poly(NIPAAm- co -PT- co -Glc) bearing a binding unit glucose (Glc) capable of recognizing sialic acid, a type of important molecular targets for cancer diagnosis and therapy, and reported the sialic acid triggered macroscopic properties switching on this smart Polymer Surface. Detailed mechanism studies indicated that multiple hydrogen bonding interactions between Glc unit and Neu5Ac destroyed the initial hydrogen bond network of the coPolymer, leading to a reversible “ contraction -to- swelling ” conformational transition of the coPolymer chains, accompanied with distinct macroscopic property switching (i.e., Surface wettability, morphology, stiffness) of the coPolymer film. And these features enabled this coPolymer to selectively capture sialic acid-containing glycopeptides from complex protein samples. This work provides an inspiration for the design of novel smart Polymeric materials with sensitive responsiveness to sialic acid, which would promote the development of sialic acid-specific bio-devices and drug delivery systems.

  • CH-π Interaction Driven Macroscopic Property Transition on Smart Polymer Surface.
    Scientific reports, 2015
    Co-Authors: Guangyan Qing, Yuting Xiong, Yuekun Lai, Taolei Sun
    Abstract:

    Life systems have evolved to utilize weak noncovalent interactions, particularly CH-π interaction, to achieve various biofunctions, for example cellular communication, immune response, and protein folding. However, for artificial materials, it remains a great challenge to recognize such weak interaction, further transform it into tunable macroscopic properties and realize special functions. Here we integrate monosaccharide-based CH-π receptor capable of recognizing aromatic peptides into a smart Polymer with three-component "Recognition-Mediating-Function" design, and report the CH-π interaction driven Surface property switching on smart Polymer film, including wettability, adhesion, viscoelasticity and stiffness. Detailed studies indicate that, the CH-π interaction induces the complexation between saccharide unit and aromatic peptide, which breaks the initial amphiphilic balance of the Polymer network, resulting in contraction-swelling conformational transition for Polymer chains and subsequent dramatic switching in Surface properties. This work not only presents a new approach to control the Surface property of materials, but also points to a broader research prospect on CH-π interaction at a macroscopic level.

J. Thome - One of the best experts on this subject based on the ideXlab platform.

  • Ultrathin antibacterial polyammonium coatings on Polymer Surfaces
    Surface & Coatings Technology, 2003
    Co-Authors: J. Thome, A. Holländer, W. Jaeger, I. Trick, C. Oehr
    Abstract:

    Abstract We have developed novel antibacterial coatings from innocuous polyammonium compounds which are chemically coupled to a Polymer Surface. For immobilization we used two strategies: In the first strategy, the Polymer Surface is plasma activated to generate radicals. Then antibacterial monomers, such as diallyldimethylammonium chloride (DADMAC) are grafted to the Surface by a radical Polymerization. In the second strategy, the Polymer Surface is plasma treated to create oxygen functionalities. Antibacterial coPolymers, such as DADMAC coPolymers, are coupled to the activated Surface. Microbiological data prove that the DADMAC coPolymers reduce the settlement of bacteria such as Micrococcus luteus (gram positive) and Escherichia coli (gram negative) by a factor of 10 5 –10 6 . The layers were characterized by X-ray photoelectron spectroscopy (XPS) and contact angle measurements. The extremely thin coatings of only 2–3 nanometers thickness do not change the material properties of the substrate.

  • Ultrathin antibacterial polyammonium coatings on Polymer Surfaces
    Surface and Coatings Technology, 2003
    Co-Authors: J. Thome, A. Holländer, W. Jaeger, I. Trick, C. Oehr
    Abstract:

    We have developed novel antibacterial coatings from innocuous polyammonium compounds which are chemically coupled to a Polymer Surface. For immobilization we used two strategies: In the first strategy, the Polymer Surface is plasma activated to generate radicals. Then antibacterial monomers, such as diallyldimethylammonium chloride (DADMAC) are grafted to the Surface by a radical Polymerization. In the second strategy, the Polymer Surface is plasma treated to create oxygen functionalities. Antibacterial coPolymers, such as DADMAC coPolymers, are coupled to the activated Surface. Microbiological data prove that the DADMAC coPolymers reduce the settlement of bacteria such as Micrococcus luteus (gram positive) and Escherichia coli (gram negative) by a factor of 10(exp 5)-10(exp 6). The layers were characterized by X-ray photoelectron spectroscopy (XPS) and contact angle measurements. The extremely thin coatings of only 2-3 nanometers thickness do not change the material properties of the substrate

Hong Yin - One of the best experts on this subject based on the ideXlab platform.

  • Two Atmospheric-pressure Plasma Sources for Polymer Surface Modification
    Plasma Chemistry and Plasma Processing, 2007
    Co-Authors: Shujun Yang, Hong Yin
    Abstract:

    Two atmospheric-pressure plasma sources were studied. One was a helium plasma generated by a RF discharge, and the other was an air plasma generated by a dielectric barrier discharge (DBD). The two plasma sources were characterized on electron density, emission spectrum, and ozone density. The modification of polyethyleneterephthalate (PET) Surfaces by the two plasmas was investigated. PET strips were exposed to the plasma at the exit of the plasma source. Water contact angles were measured for Surfaces modified with different processing parameters. The change in contact angles was monitored as a function of time. Modification mechanisms were also investigated.

Guangyan Qing - One of the best experts on this subject based on the ideXlab platform.

  • Sialic acid-triggered macroscopic properties switching on a smart Polymer Surface
    Applied Surface Science, 2018
    Co-Authors: Yuting Xiong, Guangyan Qing, Hongxi Wang, Taolei Sun
    Abstract:

    Abstract Constructing smart Surfaces with responsive Polymers capable of dynamically and reversibly changing their chemical and physical properties by responding to the recognition of biomolecules remains a challenging task. And, the key to achieving this purpose relies on the design of Polymers to precisely interact with the target molecule and successfully transform the interaction signal into tunable macroscopic properties, further achieve special bio-functions. Herein, inspired by carbohydrate–carbohydrate interaction (CCI) in life system, we developed a three-component coPolymer poly(NIPAAm- co -PT- co -Glc) bearing a binding unit glucose (Glc) capable of recognizing sialic acid, a type of important molecular targets for cancer diagnosis and therapy, and reported the sialic acid triggered macroscopic properties switching on this smart Polymer Surface. Detailed mechanism studies indicated that multiple hydrogen bonding interactions between Glc unit and Neu5Ac destroyed the initial hydrogen bond network of the coPolymer, leading to a reversible “ contraction -to- swelling ” conformational transition of the coPolymer chains, accompanied with distinct macroscopic property switching (i.e., Surface wettability, morphology, stiffness) of the coPolymer film. And these features enabled this coPolymer to selectively capture sialic acid-containing glycopeptides from complex protein samples. This work provides an inspiration for the design of novel smart Polymeric materials with sensitive responsiveness to sialic acid, which would promote the development of sialic acid-specific bio-devices and drug delivery systems.

  • CH-π Interaction Driven Macroscopic Property Transition on Smart Polymer Surface.
    Scientific reports, 2015
    Co-Authors: Guangyan Qing, Yuting Xiong, Yuekun Lai, Taolei Sun
    Abstract:

    Life systems have evolved to utilize weak noncovalent interactions, particularly CH-π interaction, to achieve various biofunctions, for example cellular communication, immune response, and protein folding. However, for artificial materials, it remains a great challenge to recognize such weak interaction, further transform it into tunable macroscopic properties and realize special functions. Here we integrate monosaccharide-based CH-π receptor capable of recognizing aromatic peptides into a smart Polymer with three-component "Recognition-Mediating-Function" design, and report the CH-π interaction driven Surface property switching on smart Polymer film, including wettability, adhesion, viscoelasticity and stiffness. Detailed studies indicate that, the CH-π interaction induces the complexation between saccharide unit and aromatic peptide, which breaks the initial amphiphilic balance of the Polymer network, resulting in contraction-swelling conformational transition for Polymer chains and subsequent dramatic switching in Surface properties. This work not only presents a new approach to control the Surface property of materials, but also points to a broader research prospect on CH-π interaction at a macroscopic level.