The Experts below are selected from a list of 288 Experts worldwide ranked by ideXlab platform
A. Ya. Vainer - One of the best experts on this subject based on the ideXlab platform.
-
1,3,5,7-Tetrasubstituted adamantanes as frameworks in the design of assemblies of porphyrin macrocycles
Doklady Chemistry, 2017Co-Authors: A. Ya. Vainer, A. M. Kovalenko, S. A. Krichevskaya, K. M. Dyumaev, L. E. Berenshtein, R. Z. FridzonAbstract:A new strategy for the synthesis of adamantane-containing Polyphenols of a porphyrin series has been suggested on the basis of Suzuki–Miyaura reaction between 1,3,5,7-tetrakis(4'-iodophenyl)adamantane and a monoboryl Derivative of substituted porphyrin. The synthesis of this porphyrin assembly on the adamantane core followed by chemical transformations of this compound has provided a possibility to synthesize the corresponding Polyphenol Derivative. The latter has been used in the development of positive photoresists for nanolithography with exposure to radiation at a wavelength 13.5 nm capable of producing topological structures with a resolution of 16 nm.
-
Hexabrominated porphyrins in the synthesis of fluorene-containing Polyphenols
Doklady Chemistry, 2017Co-Authors: A. Ya. Vainer, A. M. Kovalenko, S. A. Krichevskaya, K. M. Dyumaev, Ya. L. Babushkin, Sh. I. TaritskayaAbstract:A new strategy for the synthesis of fluorene-containing Polyphenols of porphyrin series by the Suzuki–Miyaura reaction of hexabromoporphyrin and monoboryl Derivative of substituted fluorene has been proposed. Several sequential chemical transformations of the prepared porphyrin allowed preparation of Polyphenol Derivative of the noted compound. Similar Polyphenol has been used as a basis for the design of positive photoresists for nanolithography with 13.5-nm exposing radiation, which can produce topological structures with resolution 22–16 nm.
-
Tetraboryl Derivatives of porphyrins in the synthesis of novel fluorenes
Doklady Chemistry, 2017Co-Authors: A. Ya. Vainer, A. M. Kovalenko, S. A. Krichevskaya, K. M. Dyumaev, Ya. L. Babushkin, Sh. I. TaritskayaAbstract:A new strategy for the synthesis of fluorene-containing porphyrins by Suzuki–Miyaura reaction using a tetraboryl porphyrin Derivative and a fluorene Derivative of 4-bromoaniline has been proposed. A number of consecutive chemical transformations of the prepared porphyrin have led to formation of a Polyphenol Derivative of the above compound. Positive photoresists for lithography with exposing radiation wavelength of 13.5 nm have been developed on the basis of a similar Polyphenol, which provided preparation of topological structures with a resolution of 22–16 nm.
-
Supramolecular 3,4:9,10-perylenetetracarboxylic diimide triads containing moieties of sumanene Polyphenol Derivative: Synthesis and photochemical transformations
Doklady Chemistry, 2016Co-Authors: A. Ya. Vainer, K. M. Dymaev, A. M. Kovalenko, T. D. Belskii, S. A. Krichevskaya, L. I. MartovaAbstract:A Polyphenol Derivative of the sumanene-containing triad with a central perylenetetracarboxylic diimide moiety was synthesized via several consecutive chemical transformations of N,N '-bis(3',5'-dimethoxybenzyl)-1,7-bis[4''-( N,N '-disumanenyl)aminophenyl]perylene-3,4:9,10-tetracarboxylic diimide. The phenolic hydroxyl groups of the resulting Derivative were partly protected by introduction of two different protective groups, pentaspiran and tert -butyl butyrate ones. It was shown that this modified Derivative can be used to obtain a promising positive-tone photoresists with high parameters for extreme ultraviolet nanolithography on exposure to light at 13.5 nm for the manufacture of 20 to 16 nanometer chips.
Aurelie Cubizolle - One of the best experts on this subject based on the ideXlab platform.
-
isopropyl phloroglucinol dha protects outer retinal cells against lethal dose of all trans retinal
Journal of Cellular and Molecular Medicine, 2020Co-Authors: Esperance Moine, Nathalie Jacquemot, Melissa Rosell, Claire Angebaultprouteau, Aurelie Cubizolle, Laurent Guillou, Guy LenaersAbstract:All-trans-retinal (atRAL) is a highly reactive carbonyl specie, known for its reactivity on cellular phosphatidylethanolamine in photoreceptor. It is generated by photoisomerization of 11-cis-retinal chromophore linked to opsin by the Schiff's base reaction. In ABCA4-associated autosomal recessive Stargardt macular dystrophy, atRAL results in carbonyl and oxidative stress, which leads to bisretinoid A2E, accumulation in the retinal pigment epithelium (RPE). This A2E-accumulation presents as lipofuscin fluorescent pigment, and its photooxidation causes subsequent damage. Here we describe protection against a lethal dose of atRAL in both photoreceptors and RPE in primary cultures by a lipidic Polyphenol Derivative, an isopropyl-phloroglucinol linked to DHA, referred to as IP-DHA. Next, we addressed the cellular and molecular defence mechanisms in commonly used human ARPE-19 cells. We determined that both polyunsaturated fatty acid and isopropyl substituents bond to phloroglucinol are essential to confer the highest protection. IP-DHA responds rapidly against the toxicity of atRAL and its protective effect persists. This healthy effect of IP-DHA applies to the mitochondrial respiration. IP-DHA also rescues RPE cells subjected to the toxic effects of A2E after blue light exposure. Together, our findings suggest that the beneficial role of IP-DHA in retinal cells involves both anti-carbonyl and anti-oxidative capacities.
Mehmet Aslantaş - One of the best experts on this subject based on the ideXlab platform.
-
A novel Polyphenol-based ferromagnetic polymer: synthesis, characterization and Schottky diode applications
Applied Physics A, 2015Co-Authors: Fatma Gül Yeşilbayrak, Hacı Ökkeş Demir, Şükrü Çakmaktepe, Kadem Meral, Şakir Aydoğan, Akif Arslan, Melek Fidan, Mehmet AslantaşAbstract:A Polyphenol-Derivative ferromagnetic polymer was successfully synthesized from oxidative polycondensation of 4-(1-(2-phenylhydrazono)ethyl)benzene-1,3-diol abbreviated as 2,4-PHEB, and the obtained materials were fully characterized by using UV–Vis absorption spectroscopy, Fourier transform infrared, nuclear magnetic resonance and single crystal X-ray diffraction techniques. The optical, electrochemical, fluorescence, magnetic and thermal properties of the newly synthesized compounds were investigated in detail. The results revealed that the poly(2,4-PHEB) had ferromagnetic and semi-conductive (1.59 S/cm) properties. Additionally, the poly(2,4-PHEB)/p-type Si junction device is fabricated, and it was determined that the poly(2,4-PHEB)/p-type Si junction device showed good rectifying behavior. Graphical Abstract
-
A novel Polyphenol-based ferromagnetic polymer: synthesis, characterization and Schottky diode applications
Applied Physics A, 2015Co-Authors: Fatma Gül Yeşilbayrak, Hacı Ökkeş Demir, Şükrü Çakmaktepe, Kadem Meral, Şakir Aydoğan, Akif Arslan, Melek Fidan, Mehmet AslantaşAbstract:A Polyphenol-Derivative ferromagnetic poly- mer was successfully synthesized from oxidative poly- condensation of 4-(1-(2-phenylhydrazono)ethyl)benzene- 1,3-diol abbreviated as 2,4-PHEB, and the obtained mate- rials were fully characterized by using UV-Vis absorption spectroscopy, Fourier transform infrared, nuclear magnetic resonance and single crystal X-ray diffraction techniques. The optical, electrochemical, fluorescence, magnetic and thermal properties of the newly synthesized compounds were investigated in detail. The results revealed that the poly(2,4-PHEB) had ferromagnetic and semi-conductive (1.59 S/cm) properties. Additionally, the poly(2,4-PHEB)/ p-type Si junction device is fabricated, and it was
Guy Lenaers - One of the best experts on this subject based on the ideXlab platform.
-
isopropyl phloroglucinol dha protects outer retinal cells against lethal dose of all trans retinal
Journal of Cellular and Molecular Medicine, 2020Co-Authors: Esperance Moine, Nathalie Jacquemot, Melissa Rosell, Claire Angebaultprouteau, Aurelie Cubizolle, Laurent Guillou, Guy LenaersAbstract:All-trans-retinal (atRAL) is a highly reactive carbonyl specie, known for its reactivity on cellular phosphatidylethanolamine in photoreceptor. It is generated by photoisomerization of 11-cis-retinal chromophore linked to opsin by the Schiff's base reaction. In ABCA4-associated autosomal recessive Stargardt macular dystrophy, atRAL results in carbonyl and oxidative stress, which leads to bisretinoid A2E, accumulation in the retinal pigment epithelium (RPE). This A2E-accumulation presents as lipofuscin fluorescent pigment, and its photooxidation causes subsequent damage. Here we describe protection against a lethal dose of atRAL in both photoreceptors and RPE in primary cultures by a lipidic Polyphenol Derivative, an isopropyl-phloroglucinol linked to DHA, referred to as IP-DHA. Next, we addressed the cellular and molecular defence mechanisms in commonly used human ARPE-19 cells. We determined that both polyunsaturated fatty acid and isopropyl substituents bond to phloroglucinol are essential to confer the highest protection. IP-DHA responds rapidly against the toxicity of atRAL and its protective effect persists. This healthy effect of IP-DHA applies to the mitochondrial respiration. IP-DHA also rescues RPE cells subjected to the toxic effects of A2E after blue light exposure. Together, our findings suggest that the beneficial role of IP-DHA in retinal cells involves both anti-carbonyl and anti-oxidative capacities.
S. A. Krichevskaya - One of the best experts on this subject based on the ideXlab platform.
-
1,3,5,7-Tetrasubstituted adamantanes as frameworks in the design of assemblies of porphyrin macrocycles
Doklady Chemistry, 2017Co-Authors: A. Ya. Vainer, A. M. Kovalenko, S. A. Krichevskaya, K. M. Dyumaev, L. E. Berenshtein, R. Z. FridzonAbstract:A new strategy for the synthesis of adamantane-containing Polyphenols of a porphyrin series has been suggested on the basis of Suzuki–Miyaura reaction between 1,3,5,7-tetrakis(4'-iodophenyl)adamantane and a monoboryl Derivative of substituted porphyrin. The synthesis of this porphyrin assembly on the adamantane core followed by chemical transformations of this compound has provided a possibility to synthesize the corresponding Polyphenol Derivative. The latter has been used in the development of positive photoresists for nanolithography with exposure to radiation at a wavelength 13.5 nm capable of producing topological structures with a resolution of 16 nm.
-
Hexabrominated porphyrins in the synthesis of fluorene-containing Polyphenols
Doklady Chemistry, 2017Co-Authors: A. Ya. Vainer, A. M. Kovalenko, S. A. Krichevskaya, K. M. Dyumaev, Ya. L. Babushkin, Sh. I. TaritskayaAbstract:A new strategy for the synthesis of fluorene-containing Polyphenols of porphyrin series by the Suzuki–Miyaura reaction of hexabromoporphyrin and monoboryl Derivative of substituted fluorene has been proposed. Several sequential chemical transformations of the prepared porphyrin allowed preparation of Polyphenol Derivative of the noted compound. Similar Polyphenol has been used as a basis for the design of positive photoresists for nanolithography with 13.5-nm exposing radiation, which can produce topological structures with resolution 22–16 nm.
-
Tetraboryl Derivatives of porphyrins in the synthesis of novel fluorenes
Doklady Chemistry, 2017Co-Authors: A. Ya. Vainer, A. M. Kovalenko, S. A. Krichevskaya, K. M. Dyumaev, Ya. L. Babushkin, Sh. I. TaritskayaAbstract:A new strategy for the synthesis of fluorene-containing porphyrins by Suzuki–Miyaura reaction using a tetraboryl porphyrin Derivative and a fluorene Derivative of 4-bromoaniline has been proposed. A number of consecutive chemical transformations of the prepared porphyrin have led to formation of a Polyphenol Derivative of the above compound. Positive photoresists for lithography with exposing radiation wavelength of 13.5 nm have been developed on the basis of a similar Polyphenol, which provided preparation of topological structures with a resolution of 22–16 nm.
-
Supramolecular 3,4:9,10-perylenetetracarboxylic diimide triads containing moieties of sumanene Polyphenol Derivative: Synthesis and photochemical transformations
Doklady Chemistry, 2016Co-Authors: A. Ya. Vainer, K. M. Dymaev, A. M. Kovalenko, T. D. Belskii, S. A. Krichevskaya, L. I. MartovaAbstract:A Polyphenol Derivative of the sumanene-containing triad with a central perylenetetracarboxylic diimide moiety was synthesized via several consecutive chemical transformations of N,N '-bis(3',5'-dimethoxybenzyl)-1,7-bis[4''-( N,N '-disumanenyl)aminophenyl]perylene-3,4:9,10-tetracarboxylic diimide. The phenolic hydroxyl groups of the resulting Derivative were partly protected by introduction of two different protective groups, pentaspiran and tert -butyl butyrate ones. It was shown that this modified Derivative can be used to obtain a promising positive-tone photoresists with high parameters for extreme ultraviolet nanolithography on exposure to light at 13.5 nm for the manufacture of 20 to 16 nanometer chips.