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Antti-pekka Elomaa - One of the best experts on this subject based on the ideXlab platform.

  • A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

  • CBMS - A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

Piotr Bartczak - One of the best experts on this subject based on the ideXlab platform.

  • A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

  • CBMS - A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

E. S. Connolly - One of the best experts on this subject based on the ideXlab platform.

  • Experimental Research Laser Doppler Flowmetry in non-human primate stroke studies: model refinement for Pre-Clinical Development of cerebroprotective strategies
    2020
    Co-Authors: Christopher J. Winfree, W. J. Mack, Ryan G. King, Andrew F. Ducruet, Michael E. Sughrue, James A. Mckinnell, E. S. Connolly
    Abstract:

    Summary Background. Safety, feasibility, and efficacy trials in non-human primate stroke models are essential to the evaluation of experimental therapies and their translation to humans. Although Laser Doppler Flowmetry has been successfully employed in rodent stroke to continuously monitor cerebral blood flow, it has not been applied in primate studies. This investigation examined the utility of Laser Doppler Flowmetry in refining an existing baboon model of cerebral ischemia= reperfusion. Method. Continuous Laser Doppler Flowmetry monitoring was used, in non-human primates, to document local cerebral blood flow before, during, and after middle cerebral artery territory occlusion. In each baboon (n ¼ 7) a single Doppler probe was placed into the left frontal cortex through a precoronal burr hole. Correlations between Laser Doppler Flowmetry values and latencies to Motor Evoked Potential dropout were compared using a linear regression model. Findings. Placement of the Laser Doppler probe was easily accomplished in all animals. Laser Doppler Flowmetry tracings accurately documented blood flow changes that occurred with each technical manipulation during the procedure. Laser Doppler confirmed decreased perfusion that coincided both regionally and temporally with vessel occlusion. Depth of ischemia as measured by Laser Doppler Flowmetry was associated with Motor Evoked Potential dropout latencies for individual animals. Conclusions. Continuous, single probe Laser Doppler Flowmetry is a reliable method of documenting perfusion changes following middle cerebral artery territory occlusion in a baboon model of reperfused stroke. This advanced intraoperative monitoring technique may lead to more accurate evaluation of acute stroke therapies in Pre-Clinical trials.

  • Laser Doppler Flowmetry in non-human primate stroke studies: model refinement for Pre-Clinical Development of cerebroprotective strategies
    Acta Neurochirurgica, 2003
    Co-Authors: Christopher J. Winfree, W. J. Mack, Ryan G. King, Andrew F. Ducruet, Anthony L. D'ambrosio, Michael E. Sughrue, James A. Mckinnell, E. S. Connolly
    Abstract:

    ¶Background. Safety, feasibility, and efficacy trials in non-human primate stroke models are essential to the evaluation of experimental therapies and their translation to humans. Although Laser Doppler Flowmetry has been successfully employed in rodent stroke to continuously monitor cerebral blood flow, it has not been applied in primate studies. This investigation examined the utility of Laser Doppler Flowmetry in refining an existing baboon model of cerebral ischemia/reperfusion.

Matti Iso-mustajarvi - One of the best experts on this subject based on the ideXlab platform.

  • A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

  • CBMS - A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

Hana Vrzakova - One of the best experts on this subject based on the ideXlab platform.

  • A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.

  • CBMS - A Portable System for On-Site Medical Spectral Imaging: Pre-Clinical Development and Early Evaluation
    2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS), 2018
    Co-Authors: Piotr Bartczak, Matti Iso-mustajarvi, Hana Vrzakova, Roman Bednarik, Mikael Fraunberg, Antti-pekka Elomaa
    Abstract:

    Imaging is an integral part of most operating room procedures and is used on a daily basis in the operating theater. Near real-time imaging during surgical procedures can significantly enhance the procedures by providing information about the anatomy and pathological conditions. So far, customizable spectral-imaging systems were only rarely investigated, developed and even less often installed in operational settings, especially microsurgery. In this paper we describe a design of portable imaging system for high throughput spectral characterization of ex vivo samples. The setup presented in this work was used for non-invasive collection of spectral signatures from a set of biological tissues.