The Experts below are selected from a list of 174 Experts worldwide ranked by ideXlab platform
Sara L. Jones - One of the best experts on this subject based on the ideXlab platform.
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Performance evaluation of two microbial transport media designed for preservation and transport of Chlamydiae, Mycoplasma and Ureaplasma
Journal of Medical Microbiology, 2015Co-Authors: Sara L. Jones, Kunapuli T. Madhusudhan, Krystle Agans, Karen Dearen, Jennifer Knight, Trevor Brasel, Mehdi Karamchi, Robert SherwoodAbstract:The ability of a non-propagating transport Device (test Device) to maintain the viability of clinically relevant bacteria was compared with a similar commercial Device (Predicate Device) to establish performance equivalence. Test bacteria, namely Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae and Ureaplasma urealyticum, were inoculated into the test [Puritan Medical Products Universal Transport System (UniTranz-RTTM)] and Predicate (BD Universal Viral Transport System) Devices, and incubated at 4 °C and room temperature for up to 72 h. Bacterial viability was assessed at selected time points post-incubation using shell vial assays followed by immunofluorescence staining (for Chlamydia) or by standard culture techniques (for Mycoplasma and Ureaplasma). Results indicated that the Chlamydia strains were equally stable in both test and Predicate Devices through 72 h storage, at both test temperatures. Quantifiable levels of Mycoplasma and Ureaplasma were recovered from the test and Predicate Devices throughout the storage period. Low-temperature storage improved bacterial viability when compared with room temperature storage. In addition, the Predicate Device demonstrated slightly improved performance versus the test Device in the context of Mycoplasma and Ureaplasma following 72 h storage. The overall results of the study confirmed the full performance of UniTranz-RTTM as a microbial transport medium and established equal performance with the Predicate Device.
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Performance evaluation of two universal transport media designed for preservation and transport of Chlamydiae, Mycoplasma and Ureaplasma.
Journal of medical microbiology, 2015Co-Authors: Sara L. Jones, Kunapuli T. Madhusudhan, Krystle Agans, Karen Dearen, Jennifer Knight, Trevor Brasel, Mehdi Karamchi, Robert L SherwoodAbstract:The ability of a non-propagating transport Device (test Device) to maintain the viability of clinically relevant bacteria was compared with a similar commercial Device (Predicate Device) to establish performance equivalence. Test bacteria, namely Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae and Ureaplasma urealyticum, were inoculated into the test [Puritan Medical Products Universal Transport System (UniTranz-RT(TM))] and Predicate (BD Universal Viral Transport System) Devices, and incubated at 4 °C and room temperature for up to 72 h. Bacterial viability was assessed at selected time points post-incubation using shell vial assays followed by immunofluorescence staining (for Chlamydia) or by standard culture techniques (for Mycoplasma and Ureaplasma). Results indicated that the Chlamydia strains were equally stable in both test and Predicate Devices through 72 h storage, at both test temperatures. Quantifiable levels of Mycoplasma and Ureaplasma were recovered from the test and Predicate Devices throughout the storage period. Low-temperature storage improved bacterial viability when compared with room temperature storage. In addition, the Predicate Device demonstrated slightly improved performance versus the test Device in the context of Mycoplasma and Ureaplasma following 72 h storage. The overall results of the study confirmed the full performance of UniTranz-RT(TM) as a microbial transport medium and established equal performance with the Predicate Device.
Tiago Fiorini - One of the best experts on this subject based on the ideXlab platform.
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Safety and efficacy of a novel, gradually anodized dental implant surface: A study in Yucatan mini pigs.
Clinical Implant Dentistry and Related Research, 2019Co-Authors: Cristiano Susin, Amanda Finger Stadler, Marta L. Musskopf, Mariana De Sousa Rabelo, Umberto Demoner Ramos, Tiago FioriniAbstract:BACKGROUND A newly developed dental implant system combining advancements in surface chemistry, topography, nanostructure, color, and surface energy aims to address biological challenges and expand clinical applications. PURPOSE To assess the short- and long-term safety and efficacy of a novel, gradually anodized dental implant surface/anodized abutment. MATERIALS AND METHODS Twenty-four Yucatan mini pigs (20-24 months old) received two dental implants in each jaw quadrant. Each site was randomized to receive either a commercially available anodized implant/machined abutment or a gradually anodized implant/anodized abutment with a protective layer. Animals were euthanized at 3, 6, and 13 weeks. Microcomputed tomography and histological analyses were performed. RESULTS No significant histological differences in inflammation scores, epithelium length, bone-to-implant contact, or bone density were observed between groups for any healing time. Mucosal height was significantly higher at 3 weeks for controls (Δ = 0.2 mm); no differences were observed at 6 and 13 weeks. No significant differences in radiographic bone volume, bone-to-implant contact, trabecular thickness, and crestal bone levels were observed, irrespective of healing time. Trabecular spacing was borderline significant at 3 weeks in favor of the test implant sites; no differences were observed at 6 weeks. No significant differences were observed between experimental groups at 13 weeks. CONCLUSIONS The new implant system yielded results comparable to a commercially available Predicate Device.
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Safety and efficacy of a novel, gradually anodized dental implant surface: A study in Yucatan mini pigs.
Clinical implant dentistry and related research, 2019Co-Authors: Cristiano Susin, Marta L. Musskopf, Mariana De Sousa Rabelo, Umberto Demoner Ramos, Amanda Finger Stadler, Tiago FioriniAbstract:A newly developed dental implant system combining advancements in surface chemistry, topography, nanostructure, color, and surface energy aims to address biological challenges and expand clinical applications. To assess the short- and long-term safety and efficacy of a novel, gradually anodized dental implant surface/anodized abutment. Twenty-four Yucatan mini pigs (20-24 months old) received two dental implants in each jaw quadrant. Each site was randomized to receive either a commercially available anodized implant/machined abutment or a gradually anodized implant/anodized abutment with a protective layer. Animals were euthanized at 3, 6, and 13 weeks. Microcomputed tomography and histological analyses were performed. No significant histological differences in inflammation scores, epithelium length, bone-to-implant contact, or bone density were observed between groups for any healing time. Mucosal height was significantly higher at 3 weeks for controls (Δ = 0.2 mm); no differences were observed at 6 and 13 weeks. No significant differences in radiographic bone volume, bone-to-implant contact, trabecular thickness, and crestal bone levels were observed, irrespective of healing time. Trabecular spacing was borderline significant at 3 weeks in favor of the test implant sites; no differences were observed at 6 weeks. No significant differences were observed between experimental groups at 13 weeks. The new implant system yielded results comparable to a commercially available Predicate Device. © 2019 Wiley Periodicals, Inc.
Robert Sherwood - One of the best experts on this subject based on the ideXlab platform.
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Performance evaluation of two microbial transport media designed for preservation and transport of Chlamydiae, Mycoplasma and Ureaplasma
Journal of Medical Microbiology, 2015Co-Authors: Sara L. Jones, Kunapuli T. Madhusudhan, Krystle Agans, Karen Dearen, Jennifer Knight, Trevor Brasel, Mehdi Karamchi, Robert SherwoodAbstract:The ability of a non-propagating transport Device (test Device) to maintain the viability of clinically relevant bacteria was compared with a similar commercial Device (Predicate Device) to establish performance equivalence. Test bacteria, namely Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae and Ureaplasma urealyticum, were inoculated into the test [Puritan Medical Products Universal Transport System (UniTranz-RTTM)] and Predicate (BD Universal Viral Transport System) Devices, and incubated at 4 °C and room temperature for up to 72 h. Bacterial viability was assessed at selected time points post-incubation using shell vial assays followed by immunofluorescence staining (for Chlamydia) or by standard culture techniques (for Mycoplasma and Ureaplasma). Results indicated that the Chlamydia strains were equally stable in both test and Predicate Devices through 72 h storage, at both test temperatures. Quantifiable levels of Mycoplasma and Ureaplasma were recovered from the test and Predicate Devices throughout the storage period. Low-temperature storage improved bacterial viability when compared with room temperature storage. In addition, the Predicate Device demonstrated slightly improved performance versus the test Device in the context of Mycoplasma and Ureaplasma following 72 h storage. The overall results of the study confirmed the full performance of UniTranz-RTTM as a microbial transport medium and established equal performance with the Predicate Device.
Robert L Sherwood - One of the best experts on this subject based on the ideXlab platform.
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Performance evaluation of two universal transport media designed for preservation and transport of Chlamydiae, Mycoplasma and Ureaplasma.
Journal of medical microbiology, 2015Co-Authors: Sara L. Jones, Kunapuli T. Madhusudhan, Krystle Agans, Karen Dearen, Jennifer Knight, Trevor Brasel, Mehdi Karamchi, Robert L SherwoodAbstract:The ability of a non-propagating transport Device (test Device) to maintain the viability of clinically relevant bacteria was compared with a similar commercial Device (Predicate Device) to establish performance equivalence. Test bacteria, namely Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae and Ureaplasma urealyticum, were inoculated into the test [Puritan Medical Products Universal Transport System (UniTranz-RT(TM))] and Predicate (BD Universal Viral Transport System) Devices, and incubated at 4 °C and room temperature for up to 72 h. Bacterial viability was assessed at selected time points post-incubation using shell vial assays followed by immunofluorescence staining (for Chlamydia) or by standard culture techniques (for Mycoplasma and Ureaplasma). Results indicated that the Chlamydia strains were equally stable in both test and Predicate Devices through 72 h storage, at both test temperatures. Quantifiable levels of Mycoplasma and Ureaplasma were recovered from the test and Predicate Devices throughout the storage period. Low-temperature storage improved bacterial viability when compared with room temperature storage. In addition, the Predicate Device demonstrated slightly improved performance versus the test Device in the context of Mycoplasma and Ureaplasma following 72 h storage. The overall results of the study confirmed the full performance of UniTranz-RT(TM) as a microbial transport medium and established equal performance with the Predicate Device.
Krystle Agans - One of the best experts on this subject based on the ideXlab platform.
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Performance evaluation of two microbial transport media designed for preservation and transport of Chlamydiae, Mycoplasma and Ureaplasma
Journal of Medical Microbiology, 2015Co-Authors: Sara L. Jones, Kunapuli T. Madhusudhan, Krystle Agans, Karen Dearen, Jennifer Knight, Trevor Brasel, Mehdi Karamchi, Robert SherwoodAbstract:The ability of a non-propagating transport Device (test Device) to maintain the viability of clinically relevant bacteria was compared with a similar commercial Device (Predicate Device) to establish performance equivalence. Test bacteria, namely Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae and Ureaplasma urealyticum, were inoculated into the test [Puritan Medical Products Universal Transport System (UniTranz-RTTM)] and Predicate (BD Universal Viral Transport System) Devices, and incubated at 4 °C and room temperature for up to 72 h. Bacterial viability was assessed at selected time points post-incubation using shell vial assays followed by immunofluorescence staining (for Chlamydia) or by standard culture techniques (for Mycoplasma and Ureaplasma). Results indicated that the Chlamydia strains were equally stable in both test and Predicate Devices through 72 h storage, at both test temperatures. Quantifiable levels of Mycoplasma and Ureaplasma were recovered from the test and Predicate Devices throughout the storage period. Low-temperature storage improved bacterial viability when compared with room temperature storage. In addition, the Predicate Device demonstrated slightly improved performance versus the test Device in the context of Mycoplasma and Ureaplasma following 72 h storage. The overall results of the study confirmed the full performance of UniTranz-RTTM as a microbial transport medium and established equal performance with the Predicate Device.
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Performance evaluation of two universal transport media designed for preservation and transport of Chlamydiae, Mycoplasma and Ureaplasma.
Journal of medical microbiology, 2015Co-Authors: Sara L. Jones, Kunapuli T. Madhusudhan, Krystle Agans, Karen Dearen, Jennifer Knight, Trevor Brasel, Mehdi Karamchi, Robert L SherwoodAbstract:The ability of a non-propagating transport Device (test Device) to maintain the viability of clinically relevant bacteria was compared with a similar commercial Device (Predicate Device) to establish performance equivalence. Test bacteria, namely Chlamydia trachomatis, Chlamydia pneumoniae, Mycoplasma hominis, Mycoplasma pneumoniae and Ureaplasma urealyticum, were inoculated into the test [Puritan Medical Products Universal Transport System (UniTranz-RT(TM))] and Predicate (BD Universal Viral Transport System) Devices, and incubated at 4 °C and room temperature for up to 72 h. Bacterial viability was assessed at selected time points post-incubation using shell vial assays followed by immunofluorescence staining (for Chlamydia) or by standard culture techniques (for Mycoplasma and Ureaplasma). Results indicated that the Chlamydia strains were equally stable in both test and Predicate Devices through 72 h storage, at both test temperatures. Quantifiable levels of Mycoplasma and Ureaplasma were recovered from the test and Predicate Devices throughout the storage period. Low-temperature storage improved bacterial viability when compared with room temperature storage. In addition, the Predicate Device demonstrated slightly improved performance versus the test Device in the context of Mycoplasma and Ureaplasma following 72 h storage. The overall results of the study confirmed the full performance of UniTranz-RT(TM) as a microbial transport medium and established equal performance with the Predicate Device.