Preschool Children

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Jean-louis Edmé - One of the best experts on this subject based on the ideXlab platform.

  • Quantification of shape of flow-volume loop of healthy Preschool Children and Preschool Children with wheezing disorders.
    Pediatric pulmonology, 2012
    Co-Authors: Véronique Nève, Régis Matran, Georges Baquet, Catherine-marie Methlin, Christelle Delille, Charles Boulenguez, Jean-louis Edmé
    Abstract:

    Background The earliest change associated with airflow obstruction in small airways is reflected in a concave shape on the maximum expiratory flow-volume loop (MEFVL). The shape of the MEFL changes with age but reference values for curvilinearity indices (CI) for Preschool Children have not been published. We aimed to describe the normal curvilinearity of healthy Preschool MEFVL by CI (the β angle and the ratio of maximum expiratory flow when 50% of forced vital capacity remains to be expired/peak expiratory flow (MEF50%/PEF)) and to test their capacity in detecting concavity in Preschool Children with wheezing disorders. Methods Spirometric data were obtained from 132 healthy Preschool Children and 171 3-to-5-year-old Preschool Children with wheezing disorders and reference values for CI calculated. Results Mean (SD) β angle of healthy Children was 203° (16°) and mean MEF50%/PEF of healthy Children was 0.71 (0.12) indicating convexity of MEFVL, both decreased with increasing age (P = 10−4). Children with wheezing disorders had lower z-score values of CI (P ≤ 10−6) indicating more concave MEFVL. Among the two CI, MEF50%/PEF allowed for the best discrimination between healthy Children and Children with wheezing disorders (Wilks' lambda = 0.898, P = 10−7). Conclusion These CI can detect and quantify the concavity of the descending limb of the MEFVL in Preschool Children with wheezing disorders, MEF50%/PEF having the highest sensitivity in detecting the concavity. Pediatr Pulmonol. 2012. 47:884–894. © 2012 Wiley Periodicals, Inc.

Joyce Giovannelli - One of the best experts on this subject based on the ideXlab platform.

  • DSM-III-R disorders in Preschool Children from low-income families.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1997
    Co-Authors: Kate Keenan, Daniel S. Shaw, Brenda Walsh, Eric Delliquadri, Joyce Giovannelli
    Abstract:

    ABSTRACT Objective To generate rates of DSM-III-R disorders in a sample of Preschool Children from low-income families, examine impairment ratings for Preschool Children meeting criteria for DSM-III-R disorders, and compare rates of psychopathology using DSM-III-R criteria with rates generated by the Child Behavior Checklist (CBCL). Method As part of an ongoing longitudinal study of 104 mother-child dyads from low-income families, data were gathered when Children were 5 years of age. DSM-III-R disorders were diagnosed through the administration of the Schedule for Affective Disorders and Schizophrenia for School-Age Children to the mothers, and mothers competed the CBCL. Results Rates of DSM-III-R disorders among Preschool Children from low-income families were higher than those reported in community samples, but comparable with rates for low-income school-age Children and adolescents. Children meeting criteria for DSM-III-R disorders were rated as significantly impaired. The prevalence of behavioral and emotional problems was similar by both DSM-III-R criteria and the CBCL. There was some evidence, however, that the two systems identified different Children. Conclusions DSM-III-R criteria appear to adequately identify Preschool Children with serious behavioral and emotional problems. Longitudinal studies are needed to explore further the relative utility of the DSM and CBCL in the identification of psychopathology in Preschool Children. J. Am. Acad. Child Adolesc. Psychiatry, 1997, 36(5):620–627.

Zhang Tan - One of the best experts on this subject based on the ideXlab platform.

Véronique Nève - One of the best experts on this subject based on the ideXlab platform.

  • Quantification of shape of flow-volume loop of healthy Preschool Children and Preschool Children with wheezing disorders.
    Pediatric pulmonology, 2012
    Co-Authors: Véronique Nève, Régis Matran, Georges Baquet, Catherine-marie Methlin, Christelle Delille, Charles Boulenguez, Jean-louis Edmé
    Abstract:

    Background The earliest change associated with airflow obstruction in small airways is reflected in a concave shape on the maximum expiratory flow-volume loop (MEFVL). The shape of the MEFL changes with age but reference values for curvilinearity indices (CI) for Preschool Children have not been published. We aimed to describe the normal curvilinearity of healthy Preschool MEFVL by CI (the β angle and the ratio of maximum expiratory flow when 50% of forced vital capacity remains to be expired/peak expiratory flow (MEF50%/PEF)) and to test their capacity in detecting concavity in Preschool Children with wheezing disorders. Methods Spirometric data were obtained from 132 healthy Preschool Children and 171 3-to-5-year-old Preschool Children with wheezing disorders and reference values for CI calculated. Results Mean (SD) β angle of healthy Children was 203° (16°) and mean MEF50%/PEF of healthy Children was 0.71 (0.12) indicating convexity of MEFVL, both decreased with increasing age (P = 10−4). Children with wheezing disorders had lower z-score values of CI (P ≤ 10−6) indicating more concave MEFVL. Among the two CI, MEF50%/PEF allowed for the best discrimination between healthy Children and Children with wheezing disorders (Wilks' lambda = 0.898, P = 10−7). Conclusion These CI can detect and quantify the concavity of the descending limb of the MEFVL in Preschool Children with wheezing disorders, MEF50%/PEF having the highest sensitivity in detecting the concavity. Pediatr Pulmonol. 2012. 47:884–894. © 2012 Wiley Periodicals, Inc.

Kathryn Blake - One of the best experts on this subject based on the ideXlab platform.

  • Personalized Medicine in Preschool Children with Asthma.
    Pediatric allergy immunology and pulmonology, 2017
    Co-Authors: Hengameh H. Raissy, Kathryn Blake
    Abstract:

    A growing body of literature has investigated optimizing asthma management by identifying phenotypes and biomarkers to guide the treatment. In particular, management of asthma in Preschool Children remains challenging due to different phenotype presentation in early life. The focus of this review is to summarize the recent data on personalized medicine in management of Preschool Children with wheezing.

  • Management of Wheezing in Preschool Children
    Pediatric Allergy Immunology and Pulmonology, 2012
    Co-Authors: Hengameh H. Raissy, Kathryn Blake
    Abstract:

    Diagnosis and management of asthma in Preschool Children are challenging. The Expert Panel Report 3 has recommendations for specific illness phenotypes to start long-term controller medication to reduce risk and impairment in Children ages 0–4-year old. The use of daily-inhaled corticosteroids has shown to be effective in Preschool Children with persistent asthma, but there are also reports of growth retardation. For Children with recurrent or intermittent wheezing without symptoms in between episodes, the intermittent use of controller medications may be an option for certain phenotypes. This review will discuss the available data on use of intermittent controller medications in Preschool Children with wheezing.