The Experts below are selected from a list of 37524 Experts worldwide ranked by ideXlab platform
Mimi L K Tang - One of the best experts on this subject based on the ideXlab platform.
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variability in skin Prick Test results performed by multiple operators depends on the device used
World Allergy Organization Journal, 2012Co-Authors: Rebecca L Werther, Katrina J Allen, Mimi L K Tang, Sharon Choo, Debra PooleAbstract:BACKGROUND: : The variability of skin Prick Test results when carried out by multiple users has not previously been assessed across different devices or between different sites on the body. Such multiuser variability has important implications for clinical practice. OBJECTIVES: : We assessed the variability of measurements from 4 commonly used single-headed skin Test devices when used by multiple operators and examined whether the variability in performance was different on the back compared with the forearm. METHODS: : Eight adult volunteer "operators" were trained in the use of 4 devices: Greer Pick, Quintip, Stallergenes Lancet, and Feather Lancet. Each operator performed a histamine skin Prick Test with all devices on the backs and forearms of 5 volunteer "receivers." Variability in results was assessed using a multilevel (random effects) regression model. RESULTS: : After controlling for variation between users and receivers, the residual variability or "measurement error" was least for the Stallergenes Lancet, closely followed by the Quintip. The Greer Pick had the greaTest variability. There was greater variability in measurements on the arm compared with the back. CONCLUSIONS: : The devices using the "puncture" method (Stallergenes Lancet, Quintip) provide less variability in results than those using a "Prick" method when carried out by multiple users (Greer Pick and Feather Lancet). Testing on the back also gives less variable results compared with the arm.
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frequent baked egg ingestion was not associated with change in rate of decline in egg skin Prick Test in children with challenge confirmed egg allergy
Clinical & Experimental Allergy, 2012Co-Authors: Shyamali C Dharmage, M N Robinson, Katrina J Allen, Lyle C Gurrin, Mimi L K TangAbstract:SummaryBackground It is controversial whether egg-allergic children should strictly avoid all forms of egg, or if regular ingestion of baked egg will either delay or hasten the resolution of egg allergy. Objective This is the first study to examine the relationship between frequency of baked egg ingestion and rate of decline in egg skin Prick Test size in egg-allergic children. Methodology This was a retrospective clinical cohort study. All children with challenge-proven egg allergy who attended the Royal Children's Hospital Allergy Department 1996–2005 and had at least two egg skin Prick Tests performed in this period were included (n = 125). Frequency of baked egg ingestion was assessed by telephone questionnaire as follows: (a) frequent (> once per week), (b) regular (> once every 3 months, up to ≤ once per week) or (c) strict avoidance (≤ once every 3 months). The relationship between frequency of baked egg ingestion and rate of decline in egg skin Prick Test size was examined by multiple linear regression, adjusting for potential confounders. Results Mean rate of decline in egg skin Prick Test size in all children was 0.7 mm/year (95% CI 0.5–1.0 mm/year). There was no evidence (P = 0.57) that the rate of decline in egg skin Prick Test size differed between children who undertook frequent ingestion (n = 21, mean 0.4 mm/year, 95% CI −0.3–1.2 mm/year), regular ingestion (n = 37, mean 0.9 mm/year, 95% CI 0.4–1.4 mm/year) or strict avoidance (n = 67, mean 0.7 mm/year, 95% CI 0.4–1.1 mm/year) of baked egg. Conclusions Compared with strict dietary avoidance, frequent consumption of baked egg was not associated with a different rate of decline in egg skin Prick Test size in egg-allergic children. Clinical Relevance Given that dietary restrictions can adversely impact on the family, it is reasonable to consider liberalizing baked egg in the diet of egg-allergic children.
A Vierucci - One of the best experts on this subject based on the ideXlab platform.
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skin Prick Test induced anaphylaxis
Allergy, 1995Co-Authors: Elio Novembre, R Bernardini, G Bertini, G Massai, A VierucciAbstract:: An anaphylactic reaction occurred in a 57-year-old man after a Prick by Prick Test with fresh kiwi and in a 29-year-old man after Prick Tests with some species of fish. Both patients had a history of anaphylaxis after ingestion of kiwi and fish, respectively. These cases suggest that, especially in patients with a history of anaphylaxis, all efforts should be made to minimize the risk of systemic reactions, and skin Prick Testing should be performed only in places equipped to treat anaphylaxis.
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Skin‐Prick‐Test‐induced anaphylaxis
Allergy, 1995Co-Authors: Elio Novembre, R Bernardini, G Bertini, G Massai, A VierucciAbstract:: An anaphylactic reaction occurred in a 57-year-old man after a Prick by Prick Test with fresh kiwi and in a 29-year-old man after Prick Tests with some species of fish. Both patients had a history of anaphylaxis after ingestion of kiwi and fish, respectively. These cases suggest that, especially in patients with a history of anaphylaxis, all efforts should be made to minimize the risk of systemic reactions, and skin Prick Testing should be performed only in places equipped to treat anaphylaxis.
Robert G Hamilton - One of the best experts on this subject based on the ideXlab platform.
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performance and pain tolerability of current diagnostic allergy skin Prick Test devices
The Journal of Allergy and Clinical Immunology: In Practice, 2015Co-Authors: Jody R Tversky, Yohalakshmi Chelladurai, John Mcgready, Robert G HamiltonAbstract:Background Allergen skin Prick Testing remains an essential tool for diagnosing atopic disease and guiding treatment. Sensitivity needs to be defined for newly introduced devices. Objective Our aim was to compare the performance of 10 current allergy skin Prick Test devices. Methods Single- and multiheaded skin Test devices (n = 10) were applied by a single operator in a prospective randomized manner. Histamine (1 and 6 mg/mL) and control diluent were introduced at 6 randomized locations onto the upper and lower arms of healthy subjects. Wheal and flare reactions were measured independently by 2 masked technicians. Results Twenty-four subjects provided consent, and 768 skin Tests were placed. Mean wheal diameter among devices differed from 3.0 mm (ComforTen; Hollister-Stier, Spokane, Wash) to 6.8 mm (UniTest PC; Lincoln Diagnostics, Decatur, Ill) using 1 mg/mL histamine ( P P Conclusions All 10 skin Prick Test devices displayed good analytical sensitivity and specificity; however, 3 mm cannot arbitrarily be used as a positive threshold. The use of histamine at 1 mg/mL is unacceptable for certain devices but may be preferable for the most sensitive devices. On average, there was no pain score difference between multiheaded and single-head devices.
Francine Kauffmann - One of the best experts on this subject based on the ideXlab platform.
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longitudinal observations of serum ige and skin Prick Test response
American Journal of Respiratory and Critical Care Medicine, 1995Co-Authors: Marie-pierre Oryszczyn, M.-f. Dore, I Annesi, F Neukirch, Francine KauffmannAbstract:The objective of the study was to assess skin Prick Test and IgE changes in a working population surveyed 5 yr apart and to determine whether age and smoking habits modify these changes. SPTs were performed on 223 subjects by the same method and common allergens (a mixture of grass pollens and a mixture of 95% house dust and 5% house dust mite). IgE measurements were done in duplicate by the same technique at each survey. A SPT-positive response at the first survey was highly predictive of a positive value at the second survey. The prevalence of positive SPT significantly increased in 5 yr (from 17.5 to 24.7%). A strong correlation was observed between IgE levels 5 yr apart (r = 0.92), and the IgE level appeared very stable. The initial IgE level was significantly greater among the converters than in consistently negative subjects (92.3 versus 30.1 IU/ml). Conversely, the initial IgE level was lower for the reverters than in consistently positive subjects (36.8 versus 97.0 IU/ml). In SPT negatives, non- a...
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Relationships of total IgE level, skin Prick Test response, and smoking habits.
Annals of allergy, 1991Co-Authors: Marie-pierre Oryszczyn, Annesi I, Françoise Neukirch, M.-f. Dore, Francine KauffmannAbstract:: Epidemiologic observations on 331 men showed that increased serum IgE concentration was associated with a wheal response to skin Prick Testing, but also to an erythema response in the absence of any wheal, and to heavy smoking. The association between IgE and the various skin Prick Test responses remained after taking into account smoking and asthma.
Katrina J Allen - One of the best experts on this subject based on the ideXlab platform.
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variability in skin Prick Test results performed by multiple operators depends on the device used
World Allergy Organization Journal, 2012Co-Authors: Rebecca L Werther, Katrina J Allen, Mimi L K Tang, Sharon Choo, Debra PooleAbstract:BACKGROUND: : The variability of skin Prick Test results when carried out by multiple users has not previously been assessed across different devices or between different sites on the body. Such multiuser variability has important implications for clinical practice. OBJECTIVES: : We assessed the variability of measurements from 4 commonly used single-headed skin Test devices when used by multiple operators and examined whether the variability in performance was different on the back compared with the forearm. METHODS: : Eight adult volunteer "operators" were trained in the use of 4 devices: Greer Pick, Quintip, Stallergenes Lancet, and Feather Lancet. Each operator performed a histamine skin Prick Test with all devices on the backs and forearms of 5 volunteer "receivers." Variability in results was assessed using a multilevel (random effects) regression model. RESULTS: : After controlling for variation between users and receivers, the residual variability or "measurement error" was least for the Stallergenes Lancet, closely followed by the Quintip. The Greer Pick had the greaTest variability. There was greater variability in measurements on the arm compared with the back. CONCLUSIONS: : The devices using the "puncture" method (Stallergenes Lancet, Quintip) provide less variability in results than those using a "Prick" method when carried out by multiple users (Greer Pick and Feather Lancet). Testing on the back also gives less variable results compared with the arm.
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frequent baked egg ingestion was not associated with change in rate of decline in egg skin Prick Test in children with challenge confirmed egg allergy
Clinical & Experimental Allergy, 2012Co-Authors: Shyamali C Dharmage, M N Robinson, Katrina J Allen, Lyle C Gurrin, Mimi L K TangAbstract:SummaryBackground It is controversial whether egg-allergic children should strictly avoid all forms of egg, or if regular ingestion of baked egg will either delay or hasten the resolution of egg allergy. Objective This is the first study to examine the relationship between frequency of baked egg ingestion and rate of decline in egg skin Prick Test size in egg-allergic children. Methodology This was a retrospective clinical cohort study. All children with challenge-proven egg allergy who attended the Royal Children's Hospital Allergy Department 1996–2005 and had at least two egg skin Prick Tests performed in this period were included (n = 125). Frequency of baked egg ingestion was assessed by telephone questionnaire as follows: (a) frequent (> once per week), (b) regular (> once every 3 months, up to ≤ once per week) or (c) strict avoidance (≤ once every 3 months). The relationship between frequency of baked egg ingestion and rate of decline in egg skin Prick Test size was examined by multiple linear regression, adjusting for potential confounders. Results Mean rate of decline in egg skin Prick Test size in all children was 0.7 mm/year (95% CI 0.5–1.0 mm/year). There was no evidence (P = 0.57) that the rate of decline in egg skin Prick Test size differed between children who undertook frequent ingestion (n = 21, mean 0.4 mm/year, 95% CI −0.3–1.2 mm/year), regular ingestion (n = 37, mean 0.9 mm/year, 95% CI 0.4–1.4 mm/year) or strict avoidance (n = 67, mean 0.7 mm/year, 95% CI 0.4–1.1 mm/year) of baked egg. Conclusions Compared with strict dietary avoidance, frequent consumption of baked egg was not associated with a different rate of decline in egg skin Prick Test size in egg-allergic children. Clinical Relevance Given that dietary restrictions can adversely impact on the family, it is reasonable to consider liberalizing baked egg in the diet of egg-allergic children.
