The Experts below are selected from a list of 34212 Experts worldwide ranked by ideXlab platform
Tim C Peakman - One of the best experts on this subject based on the ideXlab platform.
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design and implementation of a high throughput biological sample Processing Facility using modern manufacturing principles
International Journal of Epidemiology, 2008Co-Authors: Paul Downey, Tim C PeakmanAbstract:BACKGROUND: UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500 000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research. METHODS: Modern manufacturing principles were used to direct the development of the sample Processing Facility and automated systems. RESULTS: A fit for purpose Facility comprising technology, systems, dedicated process, infrastructure and an appropriate staff structure has been implemented that will deliver and maintain a resource that will support the long-term goals of the UK Biobank study. CONCLUSIONS: Modern manufacturing principles are appropriate for use in the development of a high throughput biological sample Processing Facility.
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Design and implementation of a high-throughput biological sample Processing Facility using modern manufacturing principles.
International journal of epidemiology, 2008Co-Authors: Paul Downey, Tim C PeakmanAbstract:UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500 000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research. Modern manufacturing principles were used to direct the development of the sample Processing Facility and automated systems. A fit for purpose Facility comprising technology, systems, dedicated process, infrastructure and an appropriate staff structure has been implemented that will deliver and maintain a resource that will support the long-term goals of the UK Biobank study. Modern manufacturing principles are appropriate for use in the development of a high throughput biological sample Processing Facility.
Paul Downey - One of the best experts on this subject based on the ideXlab platform.
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design and implementation of a high throughput biological sample Processing Facility using modern manufacturing principles
International Journal of Epidemiology, 2008Co-Authors: Paul Downey, Tim C PeakmanAbstract:BACKGROUND: UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500 000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research. METHODS: Modern manufacturing principles were used to direct the development of the sample Processing Facility and automated systems. RESULTS: A fit for purpose Facility comprising technology, systems, dedicated process, infrastructure and an appropriate staff structure has been implemented that will deliver and maintain a resource that will support the long-term goals of the UK Biobank study. CONCLUSIONS: Modern manufacturing principles are appropriate for use in the development of a high throughput biological sample Processing Facility.
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Design and implementation of a high-throughput biological sample Processing Facility using modern manufacturing principles.
International journal of epidemiology, 2008Co-Authors: Paul Downey, Tim C PeakmanAbstract:UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500 000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research. Modern manufacturing principles were used to direct the development of the sample Processing Facility and automated systems. A fit for purpose Facility comprising technology, systems, dedicated process, infrastructure and an appropriate staff structure has been implemented that will deliver and maintain a resource that will support the long-term goals of the UK Biobank study. Modern manufacturing principles are appropriate for use in the development of a high throughput biological sample Processing Facility.
James R Hebert - One of the best experts on this subject based on the ideXlab platform.
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hypertension and hematologic parameters in a community near a uranium Processing Facility
Environmental Research, 2010Co-Authors: Sara Wagner, James B Burch, Matteo Bottai, Susan M Pinney, Robin C Puett, Dwayne E Porter, John E Vena, James R HebertAbstract:Background Environmental uranium exposure originating as a byproduct of uranium Processing can impact human health. The Fernald Feed Materials Production Center functioned as a uranium Processing Facility from 1951 to 1989, and potential health effects among residents living near this plant were investigated via the Fernald Medical Monitoring Program (FMMP).
Harry D. Harmon - One of the best experts on this subject based on the ideXlab platform.
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Salt Waste Processing Facility Independent Technical Review
2007Co-Authors: Harry D. Harmon, James W. Mccullough, Hoyt JohnsonAbstract:The U.S. Department of Energy (DOE) selected Parsons as the Engineering, Procurement, and Construction (EPC) Contractor to design, construct, commission, and operate for one year the Salt Waste Processing Facility (SWPF) at the DOE Savannah River Site (SRS). The SWPF is intended to remove and concentrate the radioactive strontium (Sr), actinides, and cesium (Cs) from the bulk salt waste solutions in the SRS high-level waste tanks. The sludge and strip effluent from the SWPF that contain concentrated Sr, actinide, and Cs wastes will be sent to the SRS Defense Waste Processing Facility (DWPF), where they will be vitrified. The decontaminated salt solution (DSS) that is left after removal of the highly radioactive constituents will be sent to the SRS Saltstone Production Facility for immobilization in a grout mixture and disposal in grout vaults. The EPC provided the 35% design package to DOE for review in September 2006, and subsequently completed the remaining design products and documents for the Preliminary Design. DOE chartered an Independent Technical Review (ITR) Team to review the Preliminary Design of the SWPF, with a focus on evaluating the technical sufficiency of design to support development of a baseline cost and schedule (Critical Decision-2 [CD-2]) per DOEmore » Order 413.3A. The ITR Team concluded that the SWPF project is ready to move into final design.« less
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Overview of Fiscal Year 2002 Research and Development for Savannah River Site's Salt Waste Processing Facility
2003Co-Authors: Harry D. Harmon, P C Suggs, Samuel D. Fink, Major C. Thompson, Darrel D. Walker, R.k. Leugemors, William D ClarkAbstract:The Department of Energy's (DOE) Savannah River Site (SRS) high-level waste program is responsible for storage, treatment, and immobilization of high-level waste for disposal. The Salt Processing Program (SPP) is the salt (soluble) waste treatment portion of the SRS high-level waste effort. The overall SPP encompasses the selection, design, construction and operation of treatment technologies to prepare the salt waste feed material for the site's grout Facility (Saltstone) and vitrification Facility (Defense Waste Processing Facility). Major constituents that must be removed from the salt waste and sent as feed to Defense Waste Processing Facility include actinides, strontium, cesium, and entrained sludge. In fiscal year 2002 (FY02), research and development (R&D) on the actinide and strontium removal and Caustic-Side Solvent Extraction (CSSX) processes transitioned from technology development for baseline process selection to providing input for conceptual design of the Salt Waste Processing Facility. The SPP R&D focused on advancing the technical maturity, risk reduction, engineering development, and design support for DOE's engineering, procurement, and construction (EPC) contractors for the Salt Waste Processing Facility. Thus, R&D in FY02 addressed the areas of actual waste performance, process chemistry, engineering tests of equipment, and chemical and physical properties relevant to safety. All of the testing, studies, and reports were summarized and provided to the DOE to support the Salt Waste Processing Facility, which began conceptual design in September 2002.
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Status of the Salt Waste Processing Facility at the Savannah River Site
9th ASME International Conference on Radioactive Waste Management and Environmental Remediation: Volumes 1 2 and 3, 2003Co-Authors: Terrel J. Spears, Harry D. Harmon, James W. Mccullough, R.k. LeugemorsAbstract:The Department of Energy’s (DOE) Savannah River Site (SRS) High-Level Waste (HLW) Program is responsible for storage, treatment, and immobilization of HLW for disposal. The Salt Processing Program (SPP) is the salt (soluble) waste treatment portion of this effort. The overall SPP encompasses the selection, design, construction and operation of treatment technologies to prepare the salt waste feed material for the site’s Saltstone Facility and vitrification Facility (Defense Waste Processing Facility). Major constituents that must be removed from the salt waste include actinides, strontium, cesium, and entrained sludge. In fiscal year (FY) 2002, research and development (R&D) on the actinide and strontium removal and Caustic-Side Solvent Extraction (CSSX) processes transitioned from technology development for baseline process selection to providing input for conceptual design of the Salt Waste Processing Facility (SWPF), a key component at the SRS SPP. This work included laboratory studies, bench-scale tests, and prototype equipment development. To implement the salt waste treatment technologies, DOE initiated a competitive procurement process to select Engineering, Procurement, and Construction (EPC) contractors for design of the SWPF. The Department awarded EPC contracts to Parsons Infrastructure & Technology Group, Inc. and Foster Wheeler USA Corporation for preparation of conceptual designs (Phase I) for the SWPF. The two EPC contractors began conceptual design activities in September 2002 and are scheduled to complete this work in January 2004. After evaluation of the conceptual designs, DOE will down select one EPC contractor to continue with final design, construction, and hot commissioning (Phase II). Hot startup of the SWPF is targeted for December 2009.Copyright © 2003 by ASME
R.k. Leugemors - One of the best experts on this subject based on the ideXlab platform.
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Overview of Fiscal Year 2002 Research and Development for Savannah River Site's Salt Waste Processing Facility
2003Co-Authors: Harry D. Harmon, P C Suggs, Samuel D. Fink, Major C. Thompson, Darrel D. Walker, R.k. Leugemors, William D ClarkAbstract:The Department of Energy's (DOE) Savannah River Site (SRS) high-level waste program is responsible for storage, treatment, and immobilization of high-level waste for disposal. The Salt Processing Program (SPP) is the salt (soluble) waste treatment portion of the SRS high-level waste effort. The overall SPP encompasses the selection, design, construction and operation of treatment technologies to prepare the salt waste feed material for the site's grout Facility (Saltstone) and vitrification Facility (Defense Waste Processing Facility). Major constituents that must be removed from the salt waste and sent as feed to Defense Waste Processing Facility include actinides, strontium, cesium, and entrained sludge. In fiscal year 2002 (FY02), research and development (R&D) on the actinide and strontium removal and Caustic-Side Solvent Extraction (CSSX) processes transitioned from technology development for baseline process selection to providing input for conceptual design of the Salt Waste Processing Facility. The SPP R&D focused on advancing the technical maturity, risk reduction, engineering development, and design support for DOE's engineering, procurement, and construction (EPC) contractors for the Salt Waste Processing Facility. Thus, R&D in FY02 addressed the areas of actual waste performance, process chemistry, engineering tests of equipment, and chemical and physical properties relevant to safety. All of the testing, studies, and reports were summarized and provided to the DOE to support the Salt Waste Processing Facility, which began conceptual design in September 2002.
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Status of the Salt Waste Processing Facility at the Savannah River Site
9th ASME International Conference on Radioactive Waste Management and Environmental Remediation: Volumes 1 2 and 3, 2003Co-Authors: Terrel J. Spears, Harry D. Harmon, James W. Mccullough, R.k. LeugemorsAbstract:The Department of Energy’s (DOE) Savannah River Site (SRS) High-Level Waste (HLW) Program is responsible for storage, treatment, and immobilization of HLW for disposal. The Salt Processing Program (SPP) is the salt (soluble) waste treatment portion of this effort. The overall SPP encompasses the selection, design, construction and operation of treatment technologies to prepare the salt waste feed material for the site’s Saltstone Facility and vitrification Facility (Defense Waste Processing Facility). Major constituents that must be removed from the salt waste include actinides, strontium, cesium, and entrained sludge. In fiscal year (FY) 2002, research and development (R&D) on the actinide and strontium removal and Caustic-Side Solvent Extraction (CSSX) processes transitioned from technology development for baseline process selection to providing input for conceptual design of the Salt Waste Processing Facility (SWPF), a key component at the SRS SPP. This work included laboratory studies, bench-scale tests, and prototype equipment development. To implement the salt waste treatment technologies, DOE initiated a competitive procurement process to select Engineering, Procurement, and Construction (EPC) contractors for design of the SWPF. The Department awarded EPC contracts to Parsons Infrastructure & Technology Group, Inc. and Foster Wheeler USA Corporation for preparation of conceptual designs (Phase I) for the SWPF. The two EPC contractors began conceptual design activities in September 2002 and are scheduled to complete this work in January 2004. After evaluation of the conceptual designs, DOE will down select one EPC contractor to continue with final design, construction, and hot commissioning (Phase II). Hot startup of the SWPF is targeted for December 2009.Copyright © 2003 by ASME
