Pulmonary Carcinoid Tumour

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Rakesh Kumar - One of the best experts on this subject based on the ideXlab platform.

  • Role of ^68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid
    European Journal of Nuclear Medicine and Molecular Imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    Purpose The objective of this study was to evaluate the role of ^68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with ^18F-fluorodeoxyglucose (FDG) PET/CT scan. Methods In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with ^68Ga-DOTATOC PET/CT and ^18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Results Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of ^68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of ^18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUV_max) of TC on ^68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. ^18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). Conclusion ^68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. ^18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

  • Role of 68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid.
    European journal of nuclear medicine and molecular imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    The objective of this study was to evaluate the role of 68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with 18F-fluorodeoxyglucose (FDG) PET/CT scan. In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with 68Ga-DOTATOC PET/CT and 18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of 68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of 18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUVmax) of TC on 68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. 18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). 68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. 18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

Balasubramanian Venkitaraman - One of the best experts on this subject based on the ideXlab platform.

  • Role of ^68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid
    European Journal of Nuclear Medicine and Molecular Imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    Purpose The objective of this study was to evaluate the role of ^68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with ^18F-fluorodeoxyglucose (FDG) PET/CT scan. Methods In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with ^68Ga-DOTATOC PET/CT and ^18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Results Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of ^68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of ^18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUV_max) of TC on ^68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. ^18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). Conclusion ^68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. ^18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

  • Role of 68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid.
    European journal of nuclear medicine and molecular imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    The objective of this study was to evaluate the role of 68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with 18F-fluorodeoxyglucose (FDG) PET/CT scan. In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with 68Ga-DOTATOC PET/CT and 18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of 68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of 18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUVmax) of TC on 68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. 18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). 68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. 18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

Sellam Karunanithi - One of the best experts on this subject based on the ideXlab platform.

  • Role of ^68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid
    European Journal of Nuclear Medicine and Molecular Imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    Purpose The objective of this study was to evaluate the role of ^68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with ^18F-fluorodeoxyglucose (FDG) PET/CT scan. Methods In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with ^68Ga-DOTATOC PET/CT and ^18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Results Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of ^68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of ^18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUV_max) of TC on ^68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. ^18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). Conclusion ^68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. ^18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

  • Role of 68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid.
    European journal of nuclear medicine and molecular imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    The objective of this study was to evaluate the role of 68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with 18F-fluorodeoxyglucose (FDG) PET/CT scan. In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with 68Ga-DOTATOC PET/CT and 18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of 68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of 18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUVmax) of TC on 68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. 18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). 68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. 18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

Arvind Kumar - One of the best experts on this subject based on the ideXlab platform.

  • Role of ^68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid
    European Journal of Nuclear Medicine and Molecular Imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    Purpose The objective of this study was to evaluate the role of ^68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with ^18F-fluorodeoxyglucose (FDG) PET/CT scan. Methods In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with ^68Ga-DOTATOC PET/CT and ^18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Results Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of ^68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of ^18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUV_max) of TC on ^68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. ^18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). Conclusion ^68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. ^18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

  • Role of 68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid.
    European journal of nuclear medicine and molecular imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    The objective of this study was to evaluate the role of 68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with 18F-fluorodeoxyglucose (FDG) PET/CT scan. In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with 68Ga-DOTATOC PET/CT and 18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of 68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of 18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUVmax) of TC on 68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. 18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). 68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. 18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

G. C. Khilnani - One of the best experts on this subject based on the ideXlab platform.

  • Role of ^68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid
    European Journal of Nuclear Medicine and Molecular Imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    Purpose The objective of this study was to evaluate the role of ^68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with ^18F-fluorodeoxyglucose (FDG) PET/CT scan. Methods In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with ^68Ga-DOTATOC PET/CT and ^18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Results Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of ^68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of ^18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUV_max) of TC on ^68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. ^18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). Conclusion ^68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. ^18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.

  • Role of 68Ga-DOTATOC PET/CT in initial evaluation of patients with suspected bronchoPulmonary Carcinoid.
    European journal of nuclear medicine and molecular imaging, 2014
    Co-Authors: Balasubramanian Venkitaraman, Sellam Karunanithi, Arvind Kumar, G. C. Khilnani, Rakesh Kumar
    Abstract:

    The objective of this study was to evaluate the role of 68Ga-DOTATOC positron emission tomography (PET)/CT scan in patients with suspected Pulmonary Carcinoid Tumour and to compare its results with 18F-fluorodeoxyglucose (FDG) PET/CT scan. In this prospective study, 32 patients (age 34.22 ± 12.03 years; 53.1 % female) with clinical suspicion of bronchoPulmonary Carcinoid were evaluated with 68Ga-DOTATOC PET/CT and 18F-FDG PET/CT. The two imaging modalities were compared, considering the tissue diagnosis as the reference standard. Based on the reference standard 26 cases were Carcinoid Tumours [21 typical Carcinoids (TC) and 5 atypical Carcinoids (AC)] and 6 cases were non-Carcinoid Tumours. The sensitivity, specificity and accuracy of 68Ga-DOTATOC PET/CT in the diagnosis of Pulmonary Carcinoid Tumour were 96.15, 100 and 96.87 % respectively, whereas those of 18F-FDG PET/CT were 78.26, 11.1 and 59.37 % respectively. The maximum standardised uptake value (SUVmax) of TC on 68Ga-DOTATOC PET/CT scan ranged from 3.58 to 55, while that of AC ranged from 1.1 to 32.5. 18F-FDG PET/CT was true-positive in all cases of AC and false-negative in eight cases of TC (sensitivity for TC 61.9 % and for AC 100 %). 68Ga-DOTATOC PET/CT is a useful imaging investigation for the evaluation of Pulmonary Carcinoids. 18F-FDG PET/CT scan suffers from low sensitivity and specificity in differentiating the Pulmonary Carcinoids from other Tumours.