The Experts below are selected from a list of 10062 Experts worldwide ranked by ideXlab platform
Prachi P. Agarwal - One of the best experts on this subject based on the ideXlab platform.
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Abstract 16992: The Impact of Pulmonary Insufficiency on Patients with Surgically Repaired Pulmonary Stenosis vs. Tetralogy of Fallot by Cardiac Magnetic Resonance
Circulation, 2014Co-Authors: Michael R. Joynt, Adam L. Dorfman, Maryam Ghadimi Mahani, Prachi P. AgarwalAbstract:Background: Patients with repaired Pulmonary stenosis (PS) and tetralogy of Fallot (TOF) both develop Pulmonary Insufficiency (PI) leading to right ventricular (RV) dilatation and dysfunction. Cardiac magnetic resonance (CMR) plays a key role in determining timing of Pulmonary valve replacement (PVR) in TOF, but it is unclear whether these criteria can be extrapolated to patients with PS. We aimed to compare the differential effect of Pulmonary Insufficiency on RV volume and systolic and diastolic function in patients with surgically repaired PS and TOF. Methods: All patients with surgically repaired PS, undergoing CMR from 2007-2013, were matched 1:2 by age and Pulmonary regurgitant fraction with TOF patients. Patients with prior PVR were excluded. Right and left ventricular (LV) ejection fraction (EF), end-diastolic volume (EDV), and presence of end-diastolic forward flow in the Pulmonary artery (EDFF) were compared. Using feature tracking software (Tomtec, Unterschleissheim, Germany), RV longitudinal s...
Michael Laule - One of the best experts on this subject based on the ideXlab platform.
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transfemoral Pulmonary valve implantation for severe Pulmonary Insufficiency after ross procedure
Journal of the American College of Cardiology, 2013Co-Authors: Karl Stangl, Verena Stangl, Michael LauleAbstract:![Figure][1] [![Graphic][3] ][3][![Graphic][4] ][4] A 73-year-old woman presented with intractable right heart failure (RHF) attributable to severe Pulmonary Insufficiency ( A, [Online Video 1][4]). Six years previously, she had undergone a Ross procedure for severe aortic
Ivan M. Rebeyka - One of the best experts on this subject based on the ideXlab platform.
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Short-term effect of monocuspid valves on Pulmonary Insufficiency and clinical outcome after surgical repair of tetralogy of Fallot.
The Journal of thoracic and cardiovascular surgery, 1996Co-Authors: Jean-luc Bigras, Christine Boutin, Brian W. Mccrindle, Ivan M. RebeykaAbstract:Abstract In the surgical repair of tetralogy of Fallot, monocuspid valves are sometimes inserted within a transannular patch to prevent Pulmonary Insufficiency. To determine whether this monocuspid valve prevents short-term postoperative Pulmonary Insufficiency and improves clinical outcome, we reviewed clinical data and preoperative and postoperative echocardiographic variables from 61 patients who underwent one of three different procedures for repair of tetralogy of Fallot between August 1992 and March 1994. We compared features from 24 patients who had undergone transannular patch repair with a monocuspid valve (patch-valve) with those from 17 patients who had undergone patch repair without a monocuspid valve (patch) and 20 patients who had undergone repair without a transannular patch (no patch). We used the ratio of Pulmonary valve Insufficiency jet width to Pulmonary artery diameter, as measured by color-flow Doppler flowmetry, as an index of severity of Pulmonary Insufficiency. Moderate to severe Pulmonary Insufficiency was arbitrarily defined as a ratio of at least 0.50. We found no significant differences in ratios among the patch-valve group (0.73 ± 0.25, mean ± standard deviation), the patch group (0.79 ± 0.20), and the no patch group (0.59 ± 0.23). The percentages of patients with moderate to severe Pulmonary Insufficiency did not differ among the three groups (patch-valve 80%, patch 90%, no patch 64%). Clinical data (including mortality, number of reoperations, intensive care unit and hospital lengths of stay, and postoperative hemodynamics) were similar in the three groups. We conclude that insertion of a monocuspid valve in repair of tetralogy of Fallot does not prevent short-term postoperative Pulmonary Insufficiency and does not improve immediate postoperative outcome for these patients. (J Thorac Cardiovasc Surg 1996;112:33-7)
Harold Litt - One of the best experts on this subject based on the ideXlab platform.
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Implantation of the Medtronic Harmony Transcatheter Pulmonary Valve Improves Right Ventricular Size and Function in an Ovine Model of Postoperative Chronic Pulmonary Insufficiency
Circulation. Cardiovascular interventions, 2016Co-Authors: Rosanne C. Schoonbeek, Satoshi Takebayashi, Chikashi Aoki, Toru Shimaoka, Matthew A. Harris, Timothy S. Kim, Yoav Dori, Jeremy R. Mcgarvey, Harold LittAbstract:Background— Pulmonary Insufficiency is the nexus of late morbidity and mortality after transannular patch repair of tetralogy of Fallot. This study aimed to establish the feasibility of implantation of the novel Medtronic Harmony transcatheter Pulmonary valve (hTPV) and to assess its effect on Pulmonary Insufficiency and ventricular function in an ovine model of chronic postoperative Pulmonary Insufficiency. Methods and Results— Thirteen sheep underwent baseline cardiac magnetic resonance imaging, surgical Pulmonary valvectomy, and transannular patch repair. One month after transannular patch repair, the hTPV was implanted, followed by serial magnetic resonance imaging and computed tomography imaging at 1, 5, and 8 month(s). hTPV implantation was successful in 11 animals (85%). There were 2 procedural deaths related to ventricular fibrillation. Seven animals survived the entire follow-up protocol, 5 with functioning hTPV devices. Two animals had occlusion of hTPV with aneurysm of main Pulmonary artery. A strong decline in Pulmonary regurgitant fraction was observed after hTPV implantation (40.5% versus 8.3%; P =0.011). Right ventricular end diastolic volume increased by 49.4% after transannular patch repair (62.3–93.1 mL/m2; P =0.028) but was reversed to baseline values after hTPV implantation (to 65.1 mL/m2 at 8 months, P =0.045). Both right ventricular ejection fraction and left ventricular ejection fraction were preserved after hTPV implantation. Conclusions— hTPV implantation is feasible, significantly reduces Pulmonary regurgitant fraction, facilitates right ventricular volume improvements, and preserves biventricular function in an ovine model of chronic Pulmonary Insufficiency. This percutaneous strategy could potentially offer an alternative for standard surgical Pulmonary valve replacement in dilated right ventricular outflow tracts, permitting lower risk, nonsurgical Pulmonary valve replacement in previously prohibitive anatomies.
Michael R. Joynt - One of the best experts on this subject based on the ideXlab platform.
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Abstract 16992: The Impact of Pulmonary Insufficiency on Patients with Surgically Repaired Pulmonary Stenosis vs. Tetralogy of Fallot by Cardiac Magnetic Resonance
Circulation, 2014Co-Authors: Michael R. Joynt, Adam L. Dorfman, Maryam Ghadimi Mahani, Prachi P. AgarwalAbstract:Background: Patients with repaired Pulmonary stenosis (PS) and tetralogy of Fallot (TOF) both develop Pulmonary Insufficiency (PI) leading to right ventricular (RV) dilatation and dysfunction. Cardiac magnetic resonance (CMR) plays a key role in determining timing of Pulmonary valve replacement (PVR) in TOF, but it is unclear whether these criteria can be extrapolated to patients with PS. We aimed to compare the differential effect of Pulmonary Insufficiency on RV volume and systolic and diastolic function in patients with surgically repaired PS and TOF. Methods: All patients with surgically repaired PS, undergoing CMR from 2007-2013, were matched 1:2 by age and Pulmonary regurgitant fraction with TOF patients. Patients with prior PVR were excluded. Right and left ventricular (LV) ejection fraction (EF), end-diastolic volume (EDV), and presence of end-diastolic forward flow in the Pulmonary artery (EDFF) were compared. Using feature tracking software (Tomtec, Unterschleissheim, Germany), RV longitudinal s...
