The Experts below are selected from a list of 2247 Experts worldwide ranked by ideXlab platform
Anju Das - One of the best experts on this subject based on the ideXlab platform.
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Pylorus Ligation induced gastric ulcer protection by sesamum indicum ethanolic seed extract
Research and Reviews: A Journal of Pharmaceutical Science, 2019Co-Authors: Iswar Hazarika, Manowar Hussain, Anju DasAbstract:The present study was performed in Pylorus Ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanolic extracts 400 mg/kg of Sesamum indicum Linn. seed showed significant (P<0.001) decrease in the gastric volume, total acidity and free acidity. However, pH of the gastric juice significantly (P<0.001) increased at the dose, 400 mg/kg. It also showed a significant (P<0.001) decrease in number of ulcers and ulcer score index. In conclusion the antiulcer properties of the extracts may be attributed to the presence of phytochemical like flavonoids, saponins, alkaloids and tannins present in the plant extract with various biological activities. Keywords: Sesamum indicum Linn., Pylorus Ligation, flavonoids, ulcer index, ethanolic extract Cite this Article Manowar Hussain, Iswar Hazarika, Anju Das. Pylorus Ligation induced gastric ulcer protection by sesamum indicum ethanolic seed extract. Research & Reviews: A Journal of Pharmaceutical Science . 2015; 6(3): 42–49p.
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
2019Co-Authors: Iswar Hazarika, Manowar Hussain, Anju DasAbstract:The present study was performed in Pylorus Ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanolic extracts 400 mg/kg of Sesamum indicum Linn. seed showed significant (P
Vijaya Rajendran - One of the best experts on this subject based on the ideXlab platform.
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experimental evaluation of the anti ulcer activity of the ethanolic extract of grape vitis vinifera seed in wistar albino rats against aspirin plus Pylorus Ligation induced gastric ulcer model
International journal of basic and clinical pharmacology, 2016Co-Authors: Anand M. Ingale, Venkata Bharatkumar Pinnelli, Vijaya RajendranAbstract:Background: There is an increased demand for newer safer drugs for the treatment of peptic ulcer disease as its incidence is increasing gradually in view of changing lifestyle and stress. The objective of this study was to evaluate the anti-ulcer activity of ethanol extract of seeds of Vitis vinifera. Methods: The ethanol extract of Vitis vinifera was investigated for its anti-ulcer activity in rats against Aspirin plus Pylorus Ligation induced gastric ulcer. The antiulcer activity was assessed by determining and comparing gastric volume, pH, free and total acidity; ulcer number and its inhibition, ulcer severity and ulcer index. Results: A significant antiulcer activity was observed. Pylorus Ligation model showed significant (p<0.01) reduction in gastric volume, free acidity and ulcer index as compared to control. Conclusions: This present study indicates that Vitis vinifera seed extract have potential anti-ulcer activity in the model tested.
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Experimental evaluation of the anti-ulcer activity of the ethanolic extract of grape (Vitis vinifera) seed in wistar albino rats against aspirin plus Pylorus Ligation induced gastric ulcer model
International Journal of Basic and Clinical Pharmacology, 2016Co-Authors: Anand M. Ingale, Venkata Bharatkumar Pinnelli, Vijaya RajendranAbstract:Background: There is an increased demand for newer safer drugs for the treatment of peptic ulcer disease as its incidence is increasing gradually in view of changing lifestyle and stress. The objective of this study was to evaluate the anti-ulcer activity of ethanol extract of seeds of Vitis vinifera. Methods: The ethanol extract of Vitis vinifera was investigated for its anti-ulcer activity in rats against Aspirin plus Pylorus Ligation induced gastric ulcer. The antiulcer activity was assessed by determining and comparing gastric volume, pH, free and total acidity; ulcer number and its inhibition, ulcer severity and ulcer index. Results: A significant antiulcer activity was observed. Pylorus Ligation model showed significant (p
Iswar Hazarika - One of the best experts on this subject based on the ideXlab platform.
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Pylorus Ligation induced gastric ulcer protection by sesamum indicum ethanolic seed extract
Research and Reviews: A Journal of Pharmaceutical Science, 2019Co-Authors: Iswar Hazarika, Manowar Hussain, Anju DasAbstract:The present study was performed in Pylorus Ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanolic extracts 400 mg/kg of Sesamum indicum Linn. seed showed significant (P<0.001) decrease in the gastric volume, total acidity and free acidity. However, pH of the gastric juice significantly (P<0.001) increased at the dose, 400 mg/kg. It also showed a significant (P<0.001) decrease in number of ulcers and ulcer score index. In conclusion the antiulcer properties of the extracts may be attributed to the presence of phytochemical like flavonoids, saponins, alkaloids and tannins present in the plant extract with various biological activities. Keywords: Sesamum indicum Linn., Pylorus Ligation, flavonoids, ulcer index, ethanolic extract Cite this Article Manowar Hussain, Iswar Hazarika, Anju Das. Pylorus Ligation induced gastric ulcer protection by sesamum indicum ethanolic seed extract. Research & Reviews: A Journal of Pharmaceutical Science . 2015; 6(3): 42–49p.
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
2019Co-Authors: Iswar Hazarika, Manowar Hussain, Anju DasAbstract:The present study was performed in Pylorus Ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanolic extracts 400 mg/kg of Sesamum indicum Linn. seed showed significant (P
Anand M. Ingale - One of the best experts on this subject based on the ideXlab platform.
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experimental evaluation of the anti ulcer activity of the ethanolic extract of grape vitis vinifera seed in wistar albino rats against aspirin plus Pylorus Ligation induced gastric ulcer model
International journal of basic and clinical pharmacology, 2016Co-Authors: Anand M. Ingale, Venkata Bharatkumar Pinnelli, Vijaya RajendranAbstract:Background: There is an increased demand for newer safer drugs for the treatment of peptic ulcer disease as its incidence is increasing gradually in view of changing lifestyle and stress. The objective of this study was to evaluate the anti-ulcer activity of ethanol extract of seeds of Vitis vinifera. Methods: The ethanol extract of Vitis vinifera was investigated for its anti-ulcer activity in rats against Aspirin plus Pylorus Ligation induced gastric ulcer. The antiulcer activity was assessed by determining and comparing gastric volume, pH, free and total acidity; ulcer number and its inhibition, ulcer severity and ulcer index. Results: A significant antiulcer activity was observed. Pylorus Ligation model showed significant (p<0.01) reduction in gastric volume, free acidity and ulcer index as compared to control. Conclusions: This present study indicates that Vitis vinifera seed extract have potential anti-ulcer activity in the model tested.
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Experimental evaluation of the anti-ulcer activity of the ethanolic extract of grape (Vitis vinifera) seed in wistar albino rats against aspirin plus Pylorus Ligation induced gastric ulcer model
International Journal of Basic and Clinical Pharmacology, 2016Co-Authors: Anand M. Ingale, Venkata Bharatkumar Pinnelli, Vijaya RajendranAbstract:Background: There is an increased demand for newer safer drugs for the treatment of peptic ulcer disease as its incidence is increasing gradually in view of changing lifestyle and stress. The objective of this study was to evaluate the anti-ulcer activity of ethanol extract of seeds of Vitis vinifera. Methods: The ethanol extract of Vitis vinifera was investigated for its anti-ulcer activity in rats against Aspirin plus Pylorus Ligation induced gastric ulcer. The antiulcer activity was assessed by determining and comparing gastric volume, pH, free and total acidity; ulcer number and its inhibition, ulcer severity and ulcer index. Results: A significant antiulcer activity was observed. Pylorus Ligation model showed significant (p
Manowar Hussain - One of the best experts on this subject based on the ideXlab platform.
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Pylorus Ligation induced gastric ulcer protection by sesamum indicum ethanolic seed extract
Research and Reviews: A Journal of Pharmaceutical Science, 2019Co-Authors: Iswar Hazarika, Manowar Hussain, Anju DasAbstract:The present study was performed in Pylorus Ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanolic extracts 400 mg/kg of Sesamum indicum Linn. seed showed significant (P<0.001) decrease in the gastric volume, total acidity and free acidity. However, pH of the gastric juice significantly (P<0.001) increased at the dose, 400 mg/kg. It also showed a significant (P<0.001) decrease in number of ulcers and ulcer score index. In conclusion the antiulcer properties of the extracts may be attributed to the presence of phytochemical like flavonoids, saponins, alkaloids and tannins present in the plant extract with various biological activities. Keywords: Sesamum indicum Linn., Pylorus Ligation, flavonoids, ulcer index, ethanolic extract Cite this Article Manowar Hussain, Iswar Hazarika, Anju Das. Pylorus Ligation induced gastric ulcer protection by sesamum indicum ethanolic seed extract. Research & Reviews: A Journal of Pharmaceutical Science . 2015; 6(3): 42–49p.
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
2019Co-Authors: Iswar Hazarika, Manowar Hussain, Anju DasAbstract:The present study was performed in Pylorus Ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard drug. Pretreatment of ethanolic extracts 400 mg/kg of Sesamum indicum Linn. seed showed significant (P
