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Rudi Dierckx - One of the best experts on this subject based on the ideXlab platform.

  • comparison among tomographic Radionuclide Ventriculography algorithms for computing left and right ventricular normal limits
    Journal of Nuclear Cardiology, 2006
    Co-Authors: Pieter De Bondt, Kenneth Nichols, Rudi Dierckx, Olivier De Winter, Johan De Sutter, Marc Vanderheyden, Olakunle O Akinboboye
    Abstract:

    Background Various algorithms have been developed to compute right ventricular (RV) and left ventricular (LV) end-diastolic volumes, end-systolic volumes, and ejection fractions (EF) from tomographic Radionuclide Ventriculography (TRV). The aims of this investigation were to establish sex-specific normal limits, to determine whether different algorithms produce the same normal values, and to compare TRV normal limits vs for magnetic resonance imaging values in the literature.

  • The feasibility of repeated left ventricular ejection fraction analysis with sequential single-dose Radionuclide Ventriculography
    Nuclear Medicine Communications, 2005
    Co-Authors: Pieter A. Van Der Vleuten, Riemer H. J. A. Slart, René A. Tio, Iwan C. C. Van Der Horst, Dirk-jan Van Veldhuisen, Rudi Dierckx, Felix Zijlstra
    Abstract:

    Objective Repeated left ventricular ejection fraction (LVEF) analyses with sequential single-dose Radionuclide Ventriculography might be an interesting technique for monitoring the effect of positive inotropic interventions. The aim of the study was to assess the reproducibility of LVEF measurement with planar Radionuclide Ventriculography within 3 h, using a standard single dose of radioactive tracer. Methods Sixteen patients underwent routine planar Radionuclide Ventriculography with a standard dose of 500 MBq of [[Tc-99m]pertechnetate and returned after 3 h for a repeat planar Radionuclide Ventriculography without administration of additional tracer. Results The average initial LVEF was 35.1 +/- 18.6%-point (range, 12%-point to 68%-point). The mean difference of the LVEF between the initial planar Radionuclide Ventriculography and the repeat planar Radionuclide Ventriculography was 2.8% +/- 6.3% (range, - 11.8% to 13.3%, P= NS). The correlation between both measurements was significant with a correlation coefficient of 0.995 (P Conclusion Repeated Radionuclide Ventriculography with a 3 h interval using a single standard dose of 500 MBq of [Tc-99m]pertechnetate is highly reproducible and will be useful for monitoring the effect of positive inotropic interventions.

Mark Hyun - One of the best experts on this subject based on the ideXlab platform.

John D Friedman - One of the best experts on this subject based on the ideXlab platform.

Daniel S Berman - One of the best experts on this subject based on the ideXlab platform.

  • the differing prognostic utility of exercise Radionuclide Ventriculography in coronary artery disease patients with and without prior myocardial infarction
    International Journal of Cardiac Imaging, 1997
    Co-Authors: Mady Moriel, Alan Rozanski, Daniel S Berman, Jacob Klein, C N B Merz
    Abstract:

    Previous studies have documented the prognostic utility of left ventricular ejection fraction response to exercise primarily in populations without prior myocardial infarction. We undertook a study to assess the prognostic utility of exercise left ventricular ejection fraction and segmental wall motion response during exercise Radionuclide Ventriculography in coronary artery disease patients with and without prior myocardial infarction. Methods. We examined the comparative prognostic utility of left ventricular ejection fraction and segmental wall motion response during upright bicycle exercise Radionuclide Ventriculography in 419 coronary artery disease patients with (n=217) and without (n=202) prior myocardial infarction using univariate and multivariate hierarchical regression analyses. Results. During an average followup period of 61 months, 96 patients (23%) suffered cardiac events, including 55/217 (25%) of the patients with prior myocardial infarction and 41/200 (21%) of the patients without prior myocardial infarction (p=ns). Both cumulative Kaplan-Meier survival analyses and stepwise hierarchical Cox survival analyses demonstrated that peak left ventricular ejection fraction <55% was a significant predictor of cardiac events in patients without prior myocardial infarction (p=0.04), whereas an exercise wall motion worsening score ≥ 2 was a significant predictor in patients with a prior myocardial infarction (p=0.0001). Conclusions. The prognostic utility of exercise Radionuclide Ventriculography variables differ according to the presence or absence of prior myocardial infarction. Global function, assessed by peak left ventricular ejection fraction, adds the greatest prognostic information in patients without prior myocardial infarction, whereas regional function, assessed by exercise wall motion worsening, is the best predictor among patients with prior myocardial infarction.

  • rest and treadmill exercise first pass Radionuclide Ventriculography validation of left ventricular ejection fraction measurements
    Journal of Nuclear Cardiology, 1994
    Co-Authors: Daniel S Berman, John D Friedman, Hosen Kiat, James Bietendorf, Mark Hyun
    Abstract:

    Background To assess the accuracy of rest and treadmill exercise first-pass Radionuclide ventriculographic measurements of left ventricular ejection fraction (LVEF), 40 patients underwent treadmill exercise first-pass and bicycle exercise equilibrium Radionuclide Ventriculography. To determine the frequency of technically adequate treadmill exercise first-pass studies, an additional 128 consecutive patients undergoing treadmill exercise first-pass procedures during stress99mTc-labeled sestamibi myocardial perfusion studies were assessed.

Paul J Bohdiewicz - One of the best experts on this subject based on the ideXlab platform.

  • single photon emission computed tomography Radionuclide Ventriculography in the noninvasive diagnosis and evaluation of a false left ventricular aneurysm pseudoaneurysm
    Clinical Nuclear Medicine, 2003
    Co-Authors: Paul J Bohdiewicz
    Abstract:

    An inferior wall false aneurysm (pseudoaneurysm) was diagnosed in a 77-year-old male by single photon emission computed tomography (SPECT) Radionuclide Ventriculography (RNV). This immediately followed routine planar RNV because the latter did not lead to definitive characterization of the type of aneurysm and did not ideally characterize the location and size of the aneurysm. RNV was followed by false-negative first-pass Radionuclide Ventriculography, routine echocardiography, and gated magnetic resonance imaging of the heart (cardiac MRI). A definitive diagnosis of a false aneurysm is found at surgery and pathology; however, the patient declined surgery and has done well for 1.5 years after these imaging studies. The first-pass study is limited with relatively small pseudoaneurysms, like in this case. Echocardiography is noninvasive and can show wall motion and aneurysm size. Cardiac MRI is the most expensive noninvasive study but, in addition to revealing the diameters of the neck and body of the aneurysm, MRI is able to characterize the surrounding myocardium. This case report suggests the critical information needed for a confident, noninvasive diagnosis of false aneurysm can be obtained with SPECT RNV. The location of the aneurysm is easily determined, and the relative diameters of the neck to the body of the aneurysm can be easily seen. SPECT RNV is superior to planar RNV and first-pass Radionuclide Ventriculography in making a diagnosis of false aneurysm. Although RNV might be unable to directly demonstrate the perfusion and thickness of the myocardium, it has an advantage over MRI in terms of ejection fraction (EF) and cost.