The Experts below are selected from a list of 57228 Experts worldwide ranked by ideXlab platform
Richard P Baum - One of the best experts on this subject based on the ideXlab platform.
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meeting report from the prostate cancer foundation psma directed Radionuclide scientific working group
The Prostate, 2018Co-Authors: Andrea K Miyahira, Richard P Baum, Kenneth J Pienta, Michael J Morris, Neil H Bander, Wolfgang P Fendler, William Goeckeler, Michael A Gorin, Hartwig Hennekes, Martin G PomperAbstract:Introduction The Prostate Cancer Foundation (PCF) convened a PSMA-Directed Radionuclide Scientific Working Group on November 14, 2017, at Weill Cornell Medicine, New York, NY. Methods The meeting was attended by 35 global investigators with expertise in prostate cancer biology, Radionuclide therapy, molecular imaging, prostate-specific membrane antigen (PSMA)-targeted agents, drug development, and prostate cancer clinical trials. The goal of this meeting was to discuss the potential for using PSMA-targeted Radionuclide agents for the treatment of advanced prostate cancer and to define the studies and clinical trials necessary for validating and optimizing the use of these agents. Results Several major topic areas were discussed including the overview of PSMA biology, lessons and applications of PSMA-targeted PET imaging, the nuances of designing PSMA-targeted Radionuclide agents, clinical experiences with PSMA-targeted Radionuclides, PCF-funded projects to accelerate PSMA-targeted Radionuclide therapy, and barriers to the use of Radionuclide treatments in widespread clinical practice. Discussion This article reviews the major topics discussed at the meeting with the goal of promoting research that will validate and optimize the use of PSMA-targeted Radionuclide therapies for the treatment of advanced prostate cancer.
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generator based pet radiopharmaceuticals for molecular imaging of tumours on the way to theranostics
Dalton Transactions, 2011Co-Authors: Frank Rosch, Richard P BaumAbstract:Generator-derived Radionuclides for PET/CT imaging are promising for optimizing targeted radiotherapy by an individual patient-based approach, applying pre-therapeutic evaluation, as well as dosimetric calculations, and for measuring treatment response after Radionuclide therapy.
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generator based pet radiopharmaceuticals for molecular imaging of tumours on the way to theranostics
Dalton Transactions, 2011Co-Authors: Frank Rosch, Richard P BaumAbstract:Generator-derived Radionuclides for PET/CT imaging are promising for optimizing targeted radiotherapy by an individual patient-based approach, applying pre-therapeutic evaluation, as well as dosimetric calculations, and for measuring treatment response after Radionuclide therapy.
F Ruggieri - One of the best experts on this subject based on the ideXlab platform.
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estimation of the time dependent radioactive source term from the fukushima nuclear power plant accident using atmospheric transport modelling
Journal of Environmental Radioactivity, 2012Co-Authors: Michael Schoppner, Wolfango Plastino, P P Povinec, Gerhard Wotawa, F Bella, A Budano, Mario De Vincenzi, F RuggieriAbstract:Abstract Caesium-137 and Iodine-131 Radionuclides released after the Fukushima Dai-ichi nuclear power plant accident in March 2011 were detected at monitoring stations throughout the world. Using the CTBT Radionuclide data and the assumption that the Fukushima accident was the only source of these Radionuclides, it was possible to estimate their time-dependent source-term fourteen days following the accident by using atmospheric transport modelling. A reasonable agreement was obtained between the modelling results and the estimated Radionuclide release rates from the Fukushima accident.
S V Fesenko - One of the best experts on this subject based on the ideXlab platform.
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review of russian language studies on Radionuclide behaviour in agricultural animals biological half lives
Journal of Environmental Radioactivity, 2015Co-Authors: S V Fesenko, N Isamov, B J Howard, N A Beresford, C L Barnett, N I Sanzharova, E FesenkoAbstract:Abstract Extensive studies on transfer of Radionuclides to animals were carried out in the USSR from the 1950s. Few of these studies were published in the international refereed literature or taken into account in international reviews. This paper continues a series of reviews of Russian language literature on Radionuclide transfer to animals, providing information on biological half-lives of Radionuclides in various animal tissues. The data are compared, where possible, with those reported in other countries. The data are normally quantified using a single or double exponential accounting for different proportions of the loss. For some products, such as milk, biological half-lives tend to be rapid at 1–3 d for most Radionuclides and largely described by a single exponential. However, for other animal products biological half-lives can vary widely as they are influenced by many factors such as the age and size of the animal. Experimental protocols, such as the duration of the study, Radionuclide administration and/or sample collection protocol also influence the value of biological half-lives estimated.
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review of russian language studies on Radionuclide behaviour in agricultural animals 3 transfer to muscle
Journal of Environmental Radioactivity, 2009Co-Authors: S V Fesenko, N Isamov, B J Howard, N A Beresford, C L Barnett, N I Sanzharova, G VoigtAbstract:Data on Radionuclide transfer to domestic chickens and ducks obtained from research performed in the former Soviet Union were reviewed to provide transfer coefficient values (Ff) to poultry and edible egg contents. The majority of the data are from experiments with 90Sr and 137Cs, reflecting the importance of these Radionuclides after global fallout and major radiation accidents. Data for 3H, 54Mn, 59Fe, 60Co, 22Na 65Zn, 131I and U are also given. The values derived have been compared with those in the current IAEA Handbook of parameter values for the prediction of Radionuclide transfer in temperate environments (TRS 364) and the recent revision which incorporates the values from this paper. The Russian-language data give improved estimates for many Radionuclides and the revised handbook is now based on the better quality data given for chronic administration.
J M Godoy - One of the best experts on this subject based on the ideXlab platform.
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radioactivity concentration in liquid and solid phases of scale and sludge generated in the petroleum industry
Journal of Environmental Radioactivity, 2005Co-Authors: Maria Helena Paranhos Gazineu, Andressa Arruda De Araujo, Yana Batista Brandao, Clovis A Hazin, J M GodoyAbstract:Abstract Scales and sludge generated during oil extraction and production can contain uranium, thorium, radium and other natural Radionuclides, which can cause exposure of maintenance personnel. This work shows how the oil content can influence the results of measurements of Radionuclide concentration in scale and sludge. Samples were taken from a PETROBRAS unit in Northeast Brazil. They were collected directly from the inner surface of water pipes or from barrels stored in the waste storage area of the E&P unit. The oil was separated from the solids with a Soxhlet extractor by using aguarras at 90 ± 5°C as solvent. Concentrations of 226 Ra and 228 Ra in the samples were determined before and after oil extraction by using an HPGe gamma spectrometric system. The results showed an increase in the Radionuclide concentration in the solid (dry) phase, indicating that the above Radionuclides concentrate mostly in the solid material.
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radioactivity concentration in liquid and solid phases of scale and sludge generated in the petroleum industry
Journal of Environmental Radioactivity, 2005Co-Authors: Maria Helena Paranhos Gazineu, Andressa Arruda De Araujo, Yana Batista Brandao, Clovis A Hazin, J M GodoyAbstract:Scales and sludge generated during oil extraction and production can contain uranium, thorium, radium and other natural Radionuclides, which can cause exposure of maintenance personnel. This work shows how the oil content can influence the results of measurements of Radionuclide concentration in scale and sludge. Samples were taken from a PETROBRAS unit in Northeast Brazil. They were collected directly from the inner surface of water pipes or from barrels stored in the waste storage area of the E&P unit. The oil was separated from the solids with a Soxhlet extractor by using aguarras at 90+/-5 degrees C as solvent. Concentrations of 226Ra and 228Ra in the samples were determined before and after oil extraction by using an HPGe gamma spectrometric system. The results showed an increase in the Radionuclide concentration in the solid (dry) phase, indicating that the above Radionuclides concentrate mostly in the solid material.
I Kimlenko - One of the best experts on this subject based on the ideXlab platform.
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distribution and mobility of 137cs 90sr 239 240pu and 241 am in solid phase interstitial soil solution system
Radioprotection, 2002Co-Authors: G Sokolik, S Ovsiannikova, I KimlenkoAbstract:Analysis of the migratory properties of 137 Cs, 90 Sr, 239,240 Pu and 241 Am in different kinds of mineral and organic soils has been carried out. The Radionuclide distribution coefficient between solid and interstitial water phases of soil was used as a parameter of Radionuclide mobility. Redistribution of Radionuclides in the soil profile, soil-plant, soil-environmental water systems to a great extent depends on this parameter. Determinations of 137 Cs, 90 Sr, 239,240 Pu and 241 Am in soils, interstitial soil solutions and estimation of distribution coefficients have been realized. The soil samples were taken in areas of Gomel, Mogilev and Brest regions of Belarus that were contaminated with Radionuclides of Chernobyl origin. The influence of exchangeable Radionuclide forms and moisture capacity of soil and such characteristics of the water phase as concentration of chemical analogs of Radionuclides, organic matter and other components on distribution of 137 Cs, 90 Sr, 239,240 Pu and 241 Am in solid phase-interstitial water system has been analyzed.
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in solid phase interstitial soil solution system
2002Co-Authors: G Sokolik, S Ovsiannikova, I KimlenkoAbstract:Analysis of the migratory properties of l37 Cs, ^Sr, 229UOp\x and 24I Am in different kinds of mineral and organic soils has been carried out. The Radionuclide distribution coefficient between solid and interstitial water phases of soil was used as a parameter of Radionuclide mobility. Redistribution of Radionuclides in the soil profile, soil-plant, soil-environmental water systems to a great extent depends on this parameter. Determinations of I37 Cs, *°Sr, 239 - 240 Pu and 24l Am in soils, interstitial soil solutions and estimation of distribution coefficients have been realized. The soil samples were taken in areas of Gomel, Mogilev and Brest regions of Belarus that were contaminated with Radionuclides of Chernobyl origin. The influence of exchangeable Radionuclide forms and moisture capacity of soil and such characteristics of the water phase as concentration of chemical analogs of Radionuclides, organic matter and other components on distribution of l37 Cs, '"Sr, 239 - MO pu and J41 Am in solid phase- interstitial water system has been analyzed.
