Rat Bite Fever

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Eric C. Mcdonald - One of the best experts on this subject based on the ideXlab platform.

  • Fatal Rat-Bite Fever in a Child — San Diego County, California, 2013
    MMWR. Morbidity and mortality weekly report, 2014
    Co-Authors: Jessica K. Adam, Aiden K. Varan, Alice L. Pong, Eric C. Mcdonald
    Abstract:

    In August 2013, the County of San Diego Health and Human Services Agency was notified of a fatal case of Rat-Bite Fever (RBF) in a previously healthy male, aged 10 years, who owned pet Rats. Two days before his death, the patient experienced rigors, Fevers, vomiting, headaches, and leg pains. His physician noted a Fever of 102.6°F (39.2oC), documented a normal examination, diagnosed viral gastroenteritis, and prescribed anti-nausea medication. During the next 24 hours, the patient experienced vomiting and persistent Fever. He was confused and weak before collapsing at home. Paramedics reported the patient was unresponsive and had dilated pupils; resuscitation was initiated in the field and was continued for >1 hour after arrival at the emergency department but was unsuccessful. A complete blood count performed during resuscitation revealed anemia (hemoglobin 10.0 g/dL [normal = 13.5-18.0 g/dL], thrombocytopenia (platelets 40,000/µL [normal = 140,000-440,000/µL]), leukocytosis (white blood cells 17,900 cells/µL [normal = 4,000-10,500/µL]) with 16% band neutrophils; the patient also had evidence of disseminated intravascular coagulation. No rash or skin breakdown was noted. Lung, liver, and epiglottis tissue collected postmortem was positive for Streptobacillus moniliformis DNA by polymerase chain reaction.

  • fatal Rat Bite Fever in a child san diego county california 2013
    Morbidity and Mortality Weekly Report, 2014
    Co-Authors: Jessica K. Adam, Aiden K. Varan, Alice L. Pong, Eric C. Mcdonald
    Abstract:

    In August 2013, the County of San Diego Health and Human Services Agency was notified of a fatal case of Rat-Bite Fever (RBF) in a previously healthy male, aged 10 years, who owned pet Rats. Two days before his death, the patient experienced rigors, Fevers, vomiting, headaches, and leg pains. His physician noted a Fever of 102.6°F (39.2oC), documented a normal examination, diagnosed viral gastroenteritis, and prescribed anti-nausea medication. During the next 24 hours, the patient experienced vomiting and persistent Fever. He was confused and weak before collapsing at home. Paramedics reported the patient was unresponsive and had dilated pupils; resuscitation was initiated in the field and was continued for >1 hour after arrival at the emergency department but was unsuccessful. A complete blood count performed during resuscitation revealed anemia (hemoglobin 10.0 g/dL [normal = 13.5-18.0 g/dL], thrombocytopenia (platelets 40,000/µL [normal = 140,000-440,000/µL]), leukocytosis (white blood cells 17,900 cells/µL [normal = 4,000-10,500/µL]) with 16% band neutrophils; the patient also had evidence of disseminated intravascular coagulation. No rash or skin breakdown was noted. Lung, liver, and epiglottis tissue collected postmortem was positive for Streptobacillus moniliformis DNA by polymerase chain reaction.

Samson Sy Wong - One of the best experts on this subject based on the ideXlab platform.

  • Streptobacillus moniliformis septic arthritis: a clinical entity distinct from Rat-Bite Fever?
    BMC Infectious Diseases, 2007
    Co-Authors: Teresa Kf Wang, Samson Sy Wong
    Abstract:

    Background Streptobacillus moniliformis is a zoonotic agent associated with rodent contacts. Although it is more commonly reported to cause Rat-Bite Fever with reactive arthritides, it can also lead to pyogenic infection of the joints. Case presentation We present a lady with past history of osteoarthritis developing streptobacillary septic arthritides of the right knee and left wrist, and required antibiotic and arthrotomy for treatment. We also review 11 previously reported cases of streptobacillary septic arthritis to discuss the characteristics, treatment, prognosis of the infection, and illustRates the differences between streptobacillary Rat-Bite Fever and septic arthritis. Among this patient population, most patients had potential contact with Rats (91.6%). The knee is the most commonly affected joint (58.3%), and 83.3% patients having polyarticular involvement. As opposed to Rat-Bite Fever, Fever and rash was only present in 58.3% and 16.7% of patients respectively. S. moniliformis bacteremia is uncommon (8.4%) and the prognosis is good. Conclusion Arthrocentesis is useful in distinguishing streptobacillary septic arthritis from reactive arthritis of Rat-Bite Fever. The sole use of commercial media containing sodium polyanethol sulfonate may render the bacterial culture negative. A detailed history of possible exposure to rodents should be elicited from patients with arthritis in order to facilitate microbiologic diagnosis.

  • Streptobacillus moniliformis septic arthritis: a clinical entity distinct from Rat-Bite Fever?
    BMC infectious diseases, 2007
    Co-Authors: Teresa Kf Wang, Samson Sy Wong
    Abstract:

    Background Streptobacillus moniliformis is a zoonotic agent associated with rodent contacts. Although it is more commonly reported to cause Rat-Bite Fever with reactive arthritides, it can also lead to pyogenic infection of the joints.

Jessica K. Adam - One of the best experts on this subject based on the ideXlab platform.

  • Fatal Rat-Bite Fever in a Child — San Diego County, California, 2013
    MMWR. Morbidity and mortality weekly report, 2014
    Co-Authors: Jessica K. Adam, Aiden K. Varan, Alice L. Pong, Eric C. Mcdonald
    Abstract:

    In August 2013, the County of San Diego Health and Human Services Agency was notified of a fatal case of Rat-Bite Fever (RBF) in a previously healthy male, aged 10 years, who owned pet Rats. Two days before his death, the patient experienced rigors, Fevers, vomiting, headaches, and leg pains. His physician noted a Fever of 102.6°F (39.2oC), documented a normal examination, diagnosed viral gastroenteritis, and prescribed anti-nausea medication. During the next 24 hours, the patient experienced vomiting and persistent Fever. He was confused and weak before collapsing at home. Paramedics reported the patient was unresponsive and had dilated pupils; resuscitation was initiated in the field and was continued for >1 hour after arrival at the emergency department but was unsuccessful. A complete blood count performed during resuscitation revealed anemia (hemoglobin 10.0 g/dL [normal = 13.5-18.0 g/dL], thrombocytopenia (platelets 40,000/µL [normal = 140,000-440,000/µL]), leukocytosis (white blood cells 17,900 cells/µL [normal = 4,000-10,500/µL]) with 16% band neutrophils; the patient also had evidence of disseminated intravascular coagulation. No rash or skin breakdown was noted. Lung, liver, and epiglottis tissue collected postmortem was positive for Streptobacillus moniliformis DNA by polymerase chain reaction.

  • fatal Rat Bite Fever in a child san diego county california 2013
    Morbidity and Mortality Weekly Report, 2014
    Co-Authors: Jessica K. Adam, Aiden K. Varan, Alice L. Pong, Eric C. Mcdonald
    Abstract:

    In August 2013, the County of San Diego Health and Human Services Agency was notified of a fatal case of Rat-Bite Fever (RBF) in a previously healthy male, aged 10 years, who owned pet Rats. Two days before his death, the patient experienced rigors, Fevers, vomiting, headaches, and leg pains. His physician noted a Fever of 102.6°F (39.2oC), documented a normal examination, diagnosed viral gastroenteritis, and prescribed anti-nausea medication. During the next 24 hours, the patient experienced vomiting and persistent Fever. He was confused and weak before collapsing at home. Paramedics reported the patient was unresponsive and had dilated pupils; resuscitation was initiated in the field and was continued for >1 hour after arrival at the emergency department but was unsuccessful. A complete blood count performed during resuscitation revealed anemia (hemoglobin 10.0 g/dL [normal = 13.5-18.0 g/dL], thrombocytopenia (platelets 40,000/µL [normal = 140,000-440,000/µL]), leukocytosis (white blood cells 17,900 cells/µL [normal = 4,000-10,500/µL]) with 16% band neutrophils; the patient also had evidence of disseminated intravascular coagulation. No rash or skin breakdown was noted. Lung, liver, and epiglottis tissue collected postmortem was positive for Streptobacillus moniliformis DNA by polymerase chain reaction.

B Z Katz - One of the best experts on this subject based on the ideXlab platform.

  • Rat Bite Fever in a pet lover.
    Journal of the American Academy of Dermatology, 1998
    Co-Authors: B B Cunningham, A S Paller, B Z Katz
    Abstract:

    Rat-Bite Fever is an uncommon bacterial illness resulting from infection with Streptobacillus moniliformis that is often transmitted by the Bite of a Rat. The cutaneous findings in Rat-Bite Fever are nonspecific but have been described as maculopapular or petechial. We describe a 9-year-old girl with acrally distributed hemorrhagic pustules, Fever, and arthralgias. Diagnosis was delayed because of difficulty in identifying the pathologic organism. She was successfully treated with 10 days of ceftriaxone.

  • Rat Bite Fever in a pet lover.
    Journal of the American Academy of Dermatology, 1998
    Co-Authors: B B Cunningham, A S Paller, B Z Katz
    Abstract:

    Abstract Rat Bite Fever is an uncommon bacterial illness resulting from infection with Streptobacillus moniliformis that is often transmitted by the Bite of a Rat. The cutaneous findings in Rat Bite Fever are nonspecific but have been described as maculopapular or petechial. We describe a 9-year-old girl with acrally distributed hemorrhagic pustules, Fever, and arthralgias. Diagnosis was delayed because of difficulty in identifying the pathologic organism. She was successfully treated with 10 days of ceftriaxone. (J Am Acad Dermatol 1998;38:330-2.)

Teresa Kf Wang - One of the best experts on this subject based on the ideXlab platform.

  • Streptobacillus moniliformis septic arthritis: a clinical entity distinct from Rat-Bite Fever?
    BMC Infectious Diseases, 2007
    Co-Authors: Teresa Kf Wang, Samson Sy Wong
    Abstract:

    Background Streptobacillus moniliformis is a zoonotic agent associated with rodent contacts. Although it is more commonly reported to cause Rat-Bite Fever with reactive arthritides, it can also lead to pyogenic infection of the joints. Case presentation We present a lady with past history of osteoarthritis developing streptobacillary septic arthritides of the right knee and left wrist, and required antibiotic and arthrotomy for treatment. We also review 11 previously reported cases of streptobacillary septic arthritis to discuss the characteristics, treatment, prognosis of the infection, and illustRates the differences between streptobacillary Rat-Bite Fever and septic arthritis. Among this patient population, most patients had potential contact with Rats (91.6%). The knee is the most commonly affected joint (58.3%), and 83.3% patients having polyarticular involvement. As opposed to Rat-Bite Fever, Fever and rash was only present in 58.3% and 16.7% of patients respectively. S. moniliformis bacteremia is uncommon (8.4%) and the prognosis is good. Conclusion Arthrocentesis is useful in distinguishing streptobacillary septic arthritis from reactive arthritis of Rat-Bite Fever. The sole use of commercial media containing sodium polyanethol sulfonate may render the bacterial culture negative. A detailed history of possible exposure to rodents should be elicited from patients with arthritis in order to facilitate microbiologic diagnosis.

  • Streptobacillus moniliformis septic arthritis: a clinical entity distinct from Rat-Bite Fever?
    BMC infectious diseases, 2007
    Co-Authors: Teresa Kf Wang, Samson Sy Wong
    Abstract:

    Background Streptobacillus moniliformis is a zoonotic agent associated with rodent contacts. Although it is more commonly reported to cause Rat-Bite Fever with reactive arthritides, it can also lead to pyogenic infection of the joints.