The Experts below are selected from a list of 930 Experts worldwide ranked by ideXlab platform
Gregorij Kurillo - One of the best experts on this subject based on the ideXlab platform.
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motion sensor acquired Reachable Workspace correlates with patient reported upper extremity activities of daily living adl function in facioscapulohumeral dystrophy
Muscle & Nerve, 2020Co-Authors: Maya N. Hatch, Gregorij Kurillo, Vicky Chan, Jay J. HanAbstract:INTRODUCTION This study examines the correlation, and clinical meaningfulness, between Reachable Workspace outcome and reported activities of daily living (ADL) function of individuals with facioscapulohumeral dystrophy (FSHD). METHODS Twenty-one FSHD subjects with various disease severity (Clinical Severity Scores 1-4) underwent Reachable Workspace evaluation and completed the Neurological Disorders Quality of Life (NeuroQoL) upper extremity questionnaire. Spearman and receiver operator curve analyses were performed. RESULTS Moderate correlation was found between NeuroQoL scores and total (ρ = 0.7609; p < 0.01), and upper-quadrants RSAs (ρ = 0.6969; p < 0.01). Five specific items (i.e. shirt on, shirt off, use spoon, pull on pants, pick-up clothes) demonstrated even higher correlations with total (ρ = 0.8397; p < 0.01) and above shoulder RSAs (ρ = 0.8082; p < 0.01). A total RSA cuff-off value of 0.70 would achieve 100% sensitivity and 94% specificity (AUC = 0.975). DISCUSSION Reachable Workspace values identify when individuals have difficulties performing ADLs at home. This information improves patient monitoring, and clinical decision making by enabling more timely recommendations for medications, assistive devices or considerations for clinical trial enrollments.
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usefulness of kinect sensor based Reachable Workspace system for assessing upper extremity dysfunction in breast cancer patients
Supportive Care in Cancer, 2020Co-Authors: Kyeong Eun Uhm, Gregorij Kurillo, Jay J. Han, Seunghwan Lee, Jung-hyun Yang, Young Bum Yoo, Jongmin LeeAbstract:PURPOSE Recently, the utility of the Kinect sensor-based Reachable Workspace analysis system for measuring upper extremity outcomes of neuromuscular and musculoskeletal diseases has been demonstrated. Here, we investigated its usefulness for assessing upper extremity dysfunction in breast cancer patients. METHODS Twenty unilateral breast cancer patients were enrolled. Upper extremity active range of motion was captured by the Kinect sensor, and Reachable Workspace relative surface areas (RSAs) were obtained. The QuickDASH was completed to assess upper extremity disability. General and breast cancer-specific quality of life (QOL) were assessed by the EORTC QLQ-C30 and EORTC QLQ-BR23. RESULTS The total RSA ratio of the affected and unaffected sides ranges from 0.64 to 1.11. Total RSA was significantly reduced on the affected versus unaffected side (0.659 ± 0.105 vs. 0.762 ± 0.065; p = 0.001). Quadrant 1 and 3 RSAs were significantly reduced (0.135 ± 0.039 vs. 0.183 ± 0.040, p < 0.001; 0.172 ± 0.058 vs. 0.217 ± 0.031, p = 0.006). Total RSA of the affected side was strongly correlated with the numeric pain rating scale during movement (r = - 0.812, p < 0.001) and moderately with the QuickDASH (r = - 0.494, p = 0.027). Further, quadrant 3 RSA was correlated with EORTC QLQ-C30 role functioning (r = 0.576, p = 0.008) and EORTC QLQ-BR23 arm symptoms (r = - 0.588, p = 0.006) scales. CONCLUSIONS The Kinect sensor-based Reachable Workspace analysis system was effectively applied to assess upper extremity dysfunction in breast cancer patients. This system could potentially serve as a quick and simple outcome measure that provides quantitative data for breast cancer patients.
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longitudinal evaluation of upper extremity Reachable Workspace in als by kinect sensor
Amyotrophic Lateral Sclerosis, 2017Co-Authors: Evan De Bie, Bjorn Oskarsson, Nanette C. Joyce, Alina Nicorici, Gregorij Kurillo, Jay J. HanAbstract:Our objective was to evaluate longitudinal changes in Microsoft Kinect measured upper extremity Reachable Workspace relative surface area (RSA) versus the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R), ALSFRS-R upper extremity sub-scale and Forced Vital Capacity (FVC) in a cohort of patients diagnosed with amyotrophic lateral sclerosis (ALS). Ten patients diagnosed with ALS (ages 52-76 years, ALSFRS-R: 8-41 at entry) were tested using single 3D depth sensor, Microsoft Kinect, to measure Reachable Workspace RSA across five visits spanning one year. Changes in RSA, ALSFRS-R, ALSFRS-R upper extremity sub-scale, and FVC were assessed using a linear mixed model. Results showed that upper lateral quadrant RSA declined significantly in one year by approximately 19% (p <0.01) while all other quadrants and total RSA did not change significantly in this time-period. Simultaneously, ALSFRS-R upper extremity sub-scale worsened significantly by 25% (p <0.01). In conclusion, upper extremity Reachable Workspace RSA as a novel ALS outcome measure is capable of objectively quantifying declines in upper extremity ability over time in patients with ALS with more granularity than other common outcome measures. RSA may serve as a clinical endpoint for the evaluation of upper extremity targeted therapeutics.
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Development and Application of Stereo Camera-Based Upper Extremity Workspace Evaluation in Patients with Neuromuscular Diseases
2016Co-Authors: Gregorij Kurillo, Alina Nicorici, Jay J. Han, Richard T Abresch, Posu Yan, Ruzena BajcsyAbstract:Background: The concept of Reachable Workspace is closely tied to upper limb joint range of motion and functional capability. Currently, no practical and cost-effective methods are available in clinical and research settings to provide arm-function evaluation using an individual’s three-dimensional (3D) Reachable Workspace. A method to intuitively display and effectively analyze Reachable Workspace would not only complement traditional upper limb functional assessments, but also provide an innovative approach to quantify and monitor upper limb function. Methodology/Principal Findings: A simple stereo camera-based Reachable Workspace acquisition system combined with customized 3D Workspace analysis algorithm was developed and compared against a sub-millimeter motion capture system. The stereo camera-based system was robust, with minimal loss of data points, and with the average hand trajectory error of about 40 mm, which resulted to,5 % error of the total arm distance. As a proof-of-concept, a pilot study was undertaken with healthy individuals (n = 20) and a select group of patients with various neuromuscular diseases and varying degrees of shoulder girdle weakness (n = 9). The Workspace envelope surface areas generated from the 3D hand trajectory captured by the stereo camera were compared. Normalization of acquired Reachable Workspace surface areas to the surface area of the unit hemi-sphere allowed comparison between subjects. The healthy group’s relative surface areas were 0.61860.09 and 0.55260.092 (right and left), while the surface areas for the individuals with neuromuscular diseases range
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upper extremity 3 dimensional Reachable Workspace assessment in amyotrophic lateral sclerosis by kinect sensor
Muscle & Nerve, 2016Co-Authors: Bjorn Oskarsson, Nanette C. Joyce, Evan De Bie, Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Jay J. HanAbstract:Introduction: Reachable Workspace is a measure that provides clinically meaningful information regarding arm function. In this study, a Kinect sensor was used to determine the spectrum of 3-dimensional Reachable Workspace encountered in a cross-sectional cohort of individuals with amyotrophic lateral sclerosis (ALS). Methods: Bilateral 3D Reachable Workspace was recorded from 10 subjects with ALS and 17 healthy controls. The data were normalized by each individual's arm length to obtain a Reachable Workspace relative surface area (RSA). Concurrent validity was assessed by correlation with scoring on the ALS Functional Rating Score—revised (ALSFRSr). Results: The Kinect-measured Reachable Workspace RSA differed significantly between the ALS and control subjects (0.579 ± 0.226 vs. 0.786 ± 0.069; P < 0.001). The RSA demonstrated correlation with ALSFRSr upper extremity items (Spearman correlation ρ = 0.569; P = 0.009). With worsening upper extremity function, as categorized by the ALSFRSr, the Reachable Workspace also decreased progressively. Conclusions: This study demonstrates the feasibility and potential of using a novel Kinect-based Reachable Workspace outcome measure in ALS. Muscle Nerve 53: 234–241, 2016
Ruzena Bajcsy - One of the best experts on this subject based on the ideXlab platform.
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Development and Application of Stereo Camera-Based Upper Extremity Workspace Evaluation in Patients with Neuromuscular Diseases
2016Co-Authors: Gregorij Kurillo, Alina Nicorici, Jay J. Han, Richard T Abresch, Posu Yan, Ruzena BajcsyAbstract:Background: The concept of Reachable Workspace is closely tied to upper limb joint range of motion and functional capability. Currently, no practical and cost-effective methods are available in clinical and research settings to provide arm-function evaluation using an individual’s three-dimensional (3D) Reachable Workspace. A method to intuitively display and effectively analyze Reachable Workspace would not only complement traditional upper limb functional assessments, but also provide an innovative approach to quantify and monitor upper limb function. Methodology/Principal Findings: A simple stereo camera-based Reachable Workspace acquisition system combined with customized 3D Workspace analysis algorithm was developed and compared against a sub-millimeter motion capture system. The stereo camera-based system was robust, with minimal loss of data points, and with the average hand trajectory error of about 40 mm, which resulted to,5 % error of the total arm distance. As a proof-of-concept, a pilot study was undertaken with healthy individuals (n = 20) and a select group of patients with various neuromuscular diseases and varying degrees of shoulder girdle weakness (n = 9). The Workspace envelope surface areas generated from the 3D hand trajectory captured by the stereo camera were compared. Normalization of acquired Reachable Workspace surface areas to the surface area of the unit hemi-sphere allowed comparison between subjects. The healthy group’s relative surface areas were 0.61860.09 and 0.55260.092 (right and left), while the surface areas for the individuals with neuromuscular diseases range
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upper extremity 3d Reachable Workspace assessment in als by kinect sensor
Muscle & Nerve, 2016Co-Authors: Bjorn Oskarsson, Nanette C. Joyce, Evan De Bie, Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Jay J. HanAbstract:Introduction Reachable Workspace is a measure that provides clinically meaningful information regarding arm function. In this study, a Kinect sensor was used to determine the spectrum of 3D Reachable Workspace encountered in a cross-sectional cohort of individuals with ALS.
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upper extremity 3 dimensional Reachable Workspace assessment in amyotrophic lateral sclerosis by kinect sensor
Muscle & Nerve, 2016Co-Authors: Bjorn Oskarsson, Nanette C. Joyce, Evan De Bie, Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Jay J. HanAbstract:Introduction: Reachable Workspace is a measure that provides clinically meaningful information regarding arm function. In this study, a Kinect sensor was used to determine the spectrum of 3-dimensional Reachable Workspace encountered in a cross-sectional cohort of individuals with amyotrophic lateral sclerosis (ALS). Methods: Bilateral 3D Reachable Workspace was recorded from 10 subjects with ALS and 17 healthy controls. The data were normalized by each individual's arm length to obtain a Reachable Workspace relative surface area (RSA). Concurrent validity was assessed by correlation with scoring on the ALS Functional Rating Score—revised (ALSFRSr). Results: The Kinect-measured Reachable Workspace RSA differed significantly between the ALS and control subjects (0.579 ± 0.226 vs. 0.786 ± 0.069; P < 0.001). The RSA demonstrated correlation with ALSFRSr upper extremity items (Spearman correlation ρ = 0.569; P = 0.009). With worsening upper extremity function, as categorized by the ALSFRSr, the Reachable Workspace also decreased progressively. Conclusions: This study demonstrates the feasibility and potential of using a novel Kinect-based Reachable Workspace outcome measure in ALS. Muscle Nerve 53: 234–241, 2016
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upper extremity 3d Reachable Workspace analysis in dystrophinopathy using kinect
Muscle & Nerve, 2015Co-Authors: Jay J. Han, Evan De Bie, Alina Nicorici, Gregorij Kurillo, Richard T Abresch, Ruzena BajcsyAbstract:Introduction An innovative upper extremity 3D Reachable Workspace outcome measure acquired using Kinect sensor is applied towards Duchenne/Becker muscular dystrophy (DMD/BMD). The validity, sensitivity, and clinical meaningfulness of the novel outcome is examined.
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Reachable Workspace reflects dynamometer measured upper extremity strength in facioscapulohumeral muscular dystrophy
Muscle & Nerve, 2015Co-Authors: Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Richard T AbreschAbstract:Introduction: It is not known whether a reduction in Reachable Workspace closely reflects loss of upper extremity strength in facioscapulohumeral muscular dystrophy (FSHD). In this study we aimed to determine the relationship between Reachable Workspace and quantitative upper extremity strength measures. Methods: Maximal voluntary isometric contraction (MVIC) testing of bilateral elbow flexion and shoulder abduction by hand-held dynamometry was performed on 26 FSHD and 27 control subjects. In addition, Kinect sensor-based 3D Reachable Workspace relative surface areas (RSAs) were obtained. Loading (500-g weight) effects on Reachable Workspace were also evaluated. Results: Quantitative upper extremity strength (MVIC of elbow flexion and shoulder abduction) correlated with Kinect-acquired Reachable Workspace RSA (R = 0.477 for FSHD, P = 0.0003; R = 0.675 for the combined study cohort, P < 0.0001). Progressive reduction in RSA reflected worsening MVIC measures. Loading impacted the moderately weak individuals the most with additional reductions in RSA. Conclusions: Reachable Workspace outcome measure is reflective of upper extremity strength impairment in FSHD. Muscle Nerve 52: 948–955, 2015
Jay J. Han - One of the best experts on this subject based on the ideXlab platform.
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motion sensor acquired Reachable Workspace correlates with patient reported upper extremity activities of daily living adl function in facioscapulohumeral dystrophy
Muscle & Nerve, 2020Co-Authors: Maya N. Hatch, Gregorij Kurillo, Vicky Chan, Jay J. HanAbstract:INTRODUCTION This study examines the correlation, and clinical meaningfulness, between Reachable Workspace outcome and reported activities of daily living (ADL) function of individuals with facioscapulohumeral dystrophy (FSHD). METHODS Twenty-one FSHD subjects with various disease severity (Clinical Severity Scores 1-4) underwent Reachable Workspace evaluation and completed the Neurological Disorders Quality of Life (NeuroQoL) upper extremity questionnaire. Spearman and receiver operator curve analyses were performed. RESULTS Moderate correlation was found between NeuroQoL scores and total (ρ = 0.7609; p < 0.01), and upper-quadrants RSAs (ρ = 0.6969; p < 0.01). Five specific items (i.e. shirt on, shirt off, use spoon, pull on pants, pick-up clothes) demonstrated even higher correlations with total (ρ = 0.8397; p < 0.01) and above shoulder RSAs (ρ = 0.8082; p < 0.01). A total RSA cuff-off value of 0.70 would achieve 100% sensitivity and 94% specificity (AUC = 0.975). DISCUSSION Reachable Workspace values identify when individuals have difficulties performing ADLs at home. This information improves patient monitoring, and clinical decision making by enabling more timely recommendations for medications, assistive devices or considerations for clinical trial enrollments.
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usefulness of kinect sensor based Reachable Workspace system for assessing upper extremity dysfunction in breast cancer patients
Supportive Care in Cancer, 2020Co-Authors: Kyeong Eun Uhm, Gregorij Kurillo, Jay J. Han, Seunghwan Lee, Jung-hyun Yang, Young Bum Yoo, Jongmin LeeAbstract:PURPOSE Recently, the utility of the Kinect sensor-based Reachable Workspace analysis system for measuring upper extremity outcomes of neuromuscular and musculoskeletal diseases has been demonstrated. Here, we investigated its usefulness for assessing upper extremity dysfunction in breast cancer patients. METHODS Twenty unilateral breast cancer patients were enrolled. Upper extremity active range of motion was captured by the Kinect sensor, and Reachable Workspace relative surface areas (RSAs) were obtained. The QuickDASH was completed to assess upper extremity disability. General and breast cancer-specific quality of life (QOL) were assessed by the EORTC QLQ-C30 and EORTC QLQ-BR23. RESULTS The total RSA ratio of the affected and unaffected sides ranges from 0.64 to 1.11. Total RSA was significantly reduced on the affected versus unaffected side (0.659 ± 0.105 vs. 0.762 ± 0.065; p = 0.001). Quadrant 1 and 3 RSAs were significantly reduced (0.135 ± 0.039 vs. 0.183 ± 0.040, p < 0.001; 0.172 ± 0.058 vs. 0.217 ± 0.031, p = 0.006). Total RSA of the affected side was strongly correlated with the numeric pain rating scale during movement (r = - 0.812, p < 0.001) and moderately with the QuickDASH (r = - 0.494, p = 0.027). Further, quadrant 3 RSA was correlated with EORTC QLQ-C30 role functioning (r = 0.576, p = 0.008) and EORTC QLQ-BR23 arm symptoms (r = - 0.588, p = 0.006) scales. CONCLUSIONS The Kinect sensor-based Reachable Workspace analysis system was effectively applied to assess upper extremity dysfunction in breast cancer patients. This system could potentially serve as a quick and simple outcome measure that provides quantitative data for breast cancer patients.
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longitudinal evaluation of upper extremity Reachable Workspace in als by kinect sensor
Amyotrophic Lateral Sclerosis, 2017Co-Authors: Evan De Bie, Bjorn Oskarsson, Nanette C. Joyce, Alina Nicorici, Gregorij Kurillo, Jay J. HanAbstract:Our objective was to evaluate longitudinal changes in Microsoft Kinect measured upper extremity Reachable Workspace relative surface area (RSA) versus the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R), ALSFRS-R upper extremity sub-scale and Forced Vital Capacity (FVC) in a cohort of patients diagnosed with amyotrophic lateral sclerosis (ALS). Ten patients diagnosed with ALS (ages 52-76 years, ALSFRS-R: 8-41 at entry) were tested using single 3D depth sensor, Microsoft Kinect, to measure Reachable Workspace RSA across five visits spanning one year. Changes in RSA, ALSFRS-R, ALSFRS-R upper extremity sub-scale, and FVC were assessed using a linear mixed model. Results showed that upper lateral quadrant RSA declined significantly in one year by approximately 19% (p <0.01) while all other quadrants and total RSA did not change significantly in this time-period. Simultaneously, ALSFRS-R upper extremity sub-scale worsened significantly by 25% (p <0.01). In conclusion, upper extremity Reachable Workspace RSA as a novel ALS outcome measure is capable of objectively quantifying declines in upper extremity ability over time in patients with ALS with more granularity than other common outcome measures. RSA may serve as a clinical endpoint for the evaluation of upper extremity targeted therapeutics.
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Development and Application of Stereo Camera-Based Upper Extremity Workspace Evaluation in Patients with Neuromuscular Diseases
2016Co-Authors: Gregorij Kurillo, Alina Nicorici, Jay J. Han, Richard T Abresch, Posu Yan, Ruzena BajcsyAbstract:Background: The concept of Reachable Workspace is closely tied to upper limb joint range of motion and functional capability. Currently, no practical and cost-effective methods are available in clinical and research settings to provide arm-function evaluation using an individual’s three-dimensional (3D) Reachable Workspace. A method to intuitively display and effectively analyze Reachable Workspace would not only complement traditional upper limb functional assessments, but also provide an innovative approach to quantify and monitor upper limb function. Methodology/Principal Findings: A simple stereo camera-based Reachable Workspace acquisition system combined with customized 3D Workspace analysis algorithm was developed and compared against a sub-millimeter motion capture system. The stereo camera-based system was robust, with minimal loss of data points, and with the average hand trajectory error of about 40 mm, which resulted to,5 % error of the total arm distance. As a proof-of-concept, a pilot study was undertaken with healthy individuals (n = 20) and a select group of patients with various neuromuscular diseases and varying degrees of shoulder girdle weakness (n = 9). The Workspace envelope surface areas generated from the 3D hand trajectory captured by the stereo camera were compared. Normalization of acquired Reachable Workspace surface areas to the surface area of the unit hemi-sphere allowed comparison between subjects. The healthy group’s relative surface areas were 0.61860.09 and 0.55260.092 (right and left), while the surface areas for the individuals with neuromuscular diseases range
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upper extremity 3 dimensional Reachable Workspace assessment in amyotrophic lateral sclerosis by kinect sensor
Muscle & Nerve, 2016Co-Authors: Bjorn Oskarsson, Nanette C. Joyce, Evan De Bie, Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Jay J. HanAbstract:Introduction: Reachable Workspace is a measure that provides clinically meaningful information regarding arm function. In this study, a Kinect sensor was used to determine the spectrum of 3-dimensional Reachable Workspace encountered in a cross-sectional cohort of individuals with amyotrophic lateral sclerosis (ALS). Methods: Bilateral 3D Reachable Workspace was recorded from 10 subjects with ALS and 17 healthy controls. The data were normalized by each individual's arm length to obtain a Reachable Workspace relative surface area (RSA). Concurrent validity was assessed by correlation with scoring on the ALS Functional Rating Score—revised (ALSFRSr). Results: The Kinect-measured Reachable Workspace RSA differed significantly between the ALS and control subjects (0.579 ± 0.226 vs. 0.786 ± 0.069; P < 0.001). The RSA demonstrated correlation with ALSFRSr upper extremity items (Spearman correlation ρ = 0.569; P = 0.009). With worsening upper extremity function, as categorized by the ALSFRSr, the Reachable Workspace also decreased progressively. Conclusions: This study demonstrates the feasibility and potential of using a novel Kinect-based Reachable Workspace outcome measure in ALS. Muscle Nerve 53: 234–241, 2016
Alina Nicorici - One of the best experts on this subject based on the ideXlab platform.
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longitudinal evaluation of upper extremity Reachable Workspace in als by kinect sensor
Amyotrophic Lateral Sclerosis, 2017Co-Authors: Evan De Bie, Bjorn Oskarsson, Nanette C. Joyce, Alina Nicorici, Gregorij Kurillo, Jay J. HanAbstract:Our objective was to evaluate longitudinal changes in Microsoft Kinect measured upper extremity Reachable Workspace relative surface area (RSA) versus the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R), ALSFRS-R upper extremity sub-scale and Forced Vital Capacity (FVC) in a cohort of patients diagnosed with amyotrophic lateral sclerosis (ALS). Ten patients diagnosed with ALS (ages 52-76 years, ALSFRS-R: 8-41 at entry) were tested using single 3D depth sensor, Microsoft Kinect, to measure Reachable Workspace RSA across five visits spanning one year. Changes in RSA, ALSFRS-R, ALSFRS-R upper extremity sub-scale, and FVC were assessed using a linear mixed model. Results showed that upper lateral quadrant RSA declined significantly in one year by approximately 19% (p <0.01) while all other quadrants and total RSA did not change significantly in this time-period. Simultaneously, ALSFRS-R upper extremity sub-scale worsened significantly by 25% (p <0.01). In conclusion, upper extremity Reachable Workspace RSA as a novel ALS outcome measure is capable of objectively quantifying declines in upper extremity ability over time in patients with ALS with more granularity than other common outcome measures. RSA may serve as a clinical endpoint for the evaluation of upper extremity targeted therapeutics.
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Development and Application of Stereo Camera-Based Upper Extremity Workspace Evaluation in Patients with Neuromuscular Diseases
2016Co-Authors: Gregorij Kurillo, Alina Nicorici, Jay J. Han, Richard T Abresch, Posu Yan, Ruzena BajcsyAbstract:Background: The concept of Reachable Workspace is closely tied to upper limb joint range of motion and functional capability. Currently, no practical and cost-effective methods are available in clinical and research settings to provide arm-function evaluation using an individual’s three-dimensional (3D) Reachable Workspace. A method to intuitively display and effectively analyze Reachable Workspace would not only complement traditional upper limb functional assessments, but also provide an innovative approach to quantify and monitor upper limb function. Methodology/Principal Findings: A simple stereo camera-based Reachable Workspace acquisition system combined with customized 3D Workspace analysis algorithm was developed and compared against a sub-millimeter motion capture system. The stereo camera-based system was robust, with minimal loss of data points, and with the average hand trajectory error of about 40 mm, which resulted to,5 % error of the total arm distance. As a proof-of-concept, a pilot study was undertaken with healthy individuals (n = 20) and a select group of patients with various neuromuscular diseases and varying degrees of shoulder girdle weakness (n = 9). The Workspace envelope surface areas generated from the 3D hand trajectory captured by the stereo camera were compared. Normalization of acquired Reachable Workspace surface areas to the surface area of the unit hemi-sphere allowed comparison between subjects. The healthy group’s relative surface areas were 0.61860.09 and 0.55260.092 (right and left), while the surface areas for the individuals with neuromuscular diseases range
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upper extremity 3 dimensional Reachable Workspace assessment in amyotrophic lateral sclerosis by kinect sensor
Muscle & Nerve, 2016Co-Authors: Bjorn Oskarsson, Nanette C. Joyce, Evan De Bie, Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Jay J. HanAbstract:Introduction: Reachable Workspace is a measure that provides clinically meaningful information regarding arm function. In this study, a Kinect sensor was used to determine the spectrum of 3-dimensional Reachable Workspace encountered in a cross-sectional cohort of individuals with amyotrophic lateral sclerosis (ALS). Methods: Bilateral 3D Reachable Workspace was recorded from 10 subjects with ALS and 17 healthy controls. The data were normalized by each individual's arm length to obtain a Reachable Workspace relative surface area (RSA). Concurrent validity was assessed by correlation with scoring on the ALS Functional Rating Score—revised (ALSFRSr). Results: The Kinect-measured Reachable Workspace RSA differed significantly between the ALS and control subjects (0.579 ± 0.226 vs. 0.786 ± 0.069; P < 0.001). The RSA demonstrated correlation with ALSFRSr upper extremity items (Spearman correlation ρ = 0.569; P = 0.009). With worsening upper extremity function, as categorized by the ALSFRSr, the Reachable Workspace also decreased progressively. Conclusions: This study demonstrates the feasibility and potential of using a novel Kinect-based Reachable Workspace outcome measure in ALS. Muscle Nerve 53: 234–241, 2016
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upper extremity 3d Reachable Workspace assessment in als by kinect sensor
Muscle & Nerve, 2016Co-Authors: Bjorn Oskarsson, Nanette C. Joyce, Evan De Bie, Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Jay J. HanAbstract:Introduction Reachable Workspace is a measure that provides clinically meaningful information regarding arm function. In this study, a Kinect sensor was used to determine the spectrum of 3D Reachable Workspace encountered in a cross-sectional cohort of individuals with ALS.
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upper extremity 3d Reachable Workspace analysis in dystrophinopathy using kinect
Muscle & Nerve, 2015Co-Authors: Jay J. Han, Evan De Bie, Alina Nicorici, Gregorij Kurillo, Richard T Abresch, Ruzena BajcsyAbstract:Introduction An innovative upper extremity 3D Reachable Workspace outcome measure acquired using Kinect sensor is applied towards Duchenne/Becker muscular dystrophy (DMD/BMD). The validity, sensitivity, and clinical meaningfulness of the novel outcome is examined.
Richard T Abresch - One of the best experts on this subject based on the ideXlab platform.
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Development and Application of Stereo Camera-Based Upper Extremity Workspace Evaluation in Patients with Neuromuscular Diseases
2016Co-Authors: Gregorij Kurillo, Alina Nicorici, Jay J. Han, Richard T Abresch, Posu Yan, Ruzena BajcsyAbstract:Background: The concept of Reachable Workspace is closely tied to upper limb joint range of motion and functional capability. Currently, no practical and cost-effective methods are available in clinical and research settings to provide arm-function evaluation using an individual’s three-dimensional (3D) Reachable Workspace. A method to intuitively display and effectively analyze Reachable Workspace would not only complement traditional upper limb functional assessments, but also provide an innovative approach to quantify and monitor upper limb function. Methodology/Principal Findings: A simple stereo camera-based Reachable Workspace acquisition system combined with customized 3D Workspace analysis algorithm was developed and compared against a sub-millimeter motion capture system. The stereo camera-based system was robust, with minimal loss of data points, and with the average hand trajectory error of about 40 mm, which resulted to,5 % error of the total arm distance. As a proof-of-concept, a pilot study was undertaken with healthy individuals (n = 20) and a select group of patients with various neuromuscular diseases and varying degrees of shoulder girdle weakness (n = 9). The Workspace envelope surface areas generated from the 3D hand trajectory captured by the stereo camera were compared. Normalization of acquired Reachable Workspace surface areas to the surface area of the unit hemi-sphere allowed comparison between subjects. The healthy group’s relative surface areas were 0.61860.09 and 0.55260.092 (right and left), while the surface areas for the individuals with neuromuscular diseases range
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upper extremity 3d Reachable Workspace analysis in dystrophinopathy using kinect
Muscle & Nerve, 2015Co-Authors: Jay J. Han, Evan De Bie, Alina Nicorici, Gregorij Kurillo, Richard T Abresch, Ruzena BajcsyAbstract:Introduction An innovative upper extremity 3D Reachable Workspace outcome measure acquired using Kinect sensor is applied towards Duchenne/Becker muscular dystrophy (DMD/BMD). The validity, sensitivity, and clinical meaningfulness of the novel outcome is examined.
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Reachable Workspace reflects dynamometer measured upper extremity strength in facioscapulohumeral muscular dystrophy
Muscle & Nerve, 2015Co-Authors: Alina Nicorici, Ruzena Bajcsy, Gregorij Kurillo, Richard T AbreschAbstract:Introduction: It is not known whether a reduction in Reachable Workspace closely reflects loss of upper extremity strength in facioscapulohumeral muscular dystrophy (FSHD). In this study we aimed to determine the relationship between Reachable Workspace and quantitative upper extremity strength measures. Methods: Maximal voluntary isometric contraction (MVIC) testing of bilateral elbow flexion and shoulder abduction by hand-held dynamometry was performed on 26 FSHD and 27 control subjects. In addition, Kinect sensor-based 3D Reachable Workspace relative surface areas (RSAs) were obtained. Loading (500-g weight) effects on Reachable Workspace were also evaluated. Results: Quantitative upper extremity strength (MVIC of elbow flexion and shoulder abduction) correlated with Kinect-acquired Reachable Workspace RSA (R = 0.477 for FSHD, P = 0.0003; R = 0.675 for the combined study cohort, P < 0.0001). Progressive reduction in RSA reflected worsening MVIC measures. Loading impacted the moderately weak individuals the most with additional reductions in RSA. Conclusions: Reachable Workspace outcome measure is reflective of upper extremity strength impairment in FSHD. Muscle Nerve 52: 948–955, 2015
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Upper extremity 3-dimensional Reachable Workspace analysis in dystrophinopathy using Kinect
Muscle & Nerve, 2015Co-Authors: Jay J. Han, Evan De Bie, Alina Nicorici, Gregorij Kurillo, Richard T Abresch, Ruzena BajcsyAbstract:Introduction: An innovative upper extremity 3-dimensional (3D) Reachable Workspace outcome measure acquired using the Kinect sensor is applied toward Duchenne/Becker muscular dystrophy (DMD/BMD). The validity, sensitivity, and clinical meaningfulness of this novel outcome measure are examined. Methods: Upper extremity function assessment (Brooke scale and NeuroQOL questionnaire) and Kinect-based Reachable Workspace analyses were conducted in 43 individuals with dystrophinopathy (30 DMD and 13 BMD, aged 7–60 years) and 46 controls (aged 6–68 years). Results: The Reachable Workspace measure reliably captured a wide range of upper extremity impairments encountered in both pediatric and adult, as well as ambulatory and non-ambulatory individuals with dystrophinopathy. Reduced Reachable Workspaces were noted for the dystrophinopathy cohort compared with controls, and they correlated with Brooke grades. In addition, progressive reduction in Reachable Workspace correlated directly with worsening ability to perform activities of daily living, as self-reported on the NeuroQOL. Conclusion: This study demonstrates the utility and potential of the novel sensor-acquired Reachable Workspace outcome measure in dystrophinopathy. Muscle Nerve 52:344–355, 2015
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Reachable Workspace in facioscapulohumeral muscular dystrophy fshd by kinect
Muscle & Nerve, 2015Co-Authors: Alina Nicorici, Gregorij Kurillo, Richard T Abresch, Ruzena BajcsyAbstract:Introduction: A depth-ranging sensor (Kinect) based upper extremity motion analysis system was applied to determine the spectrum of Reachable Workspace encountered in facioscapulohumeral muscular dystrophy (FSHD). Methods: Reachable Workspaces were obtained from 22 individuals with FSHD and 24 age- and height-matched healthy controls. To allow comparison, total and quadrant Reachable Workspace relative surface areas (RSAs) were obtained by normalizing the acquired Reachable Workspace by each individual's arm length. Results: Significantly contracted Reachable Workspace and reduced RSAs were noted for the FSHD cohort compared with controls (0.473 ± 0.188 vs. 0.747 ± 0.082; P < 0.0001). With worsening upper extremity function as categorized by the FSHD evaluation subscale II + III, the upper quadrant RSAs decreased progressively, while the lower quadrant RSAs were relatively preserved. There were no side-to-side differences in Reachable Workspace based on hand-dominance. Conclusions: This study demonstrates the feasibility and potential of using an innovative Kinect-based Reachable Workspace outcome measure in FSHD. Muscle Nerve 51: 168–175, 2015