The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform
Gómez Ms - One of the best experts on this subject based on the ideXlab platform.
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Pagetoid dyskeratosis of the cervix: an incidental histologic finding in uterine prolapse.
The American Journal of Surgical Pathology, 2000Co-Authors: Val-bernal Jf, Garijo Mf, Pinto J, Gómez MsAbstract:Pagetoid dyskeratosis, is considered a Reactive Process in which a small part of the normal population of keratinocytes is induced to proliferate. The lesion is characterized by pale cells resembling those of Paget's disease within the epidermis. These cells have been seen as an incidental finding in a variety of benign papules most commonly located in intertriginous areas. Among the inductors of the lesion, friction is suspected. To the best of our knowledge, these pale cells have not been reported in the cervix. We describe the location of the lesion in the ectocervix and the incidence of this lesion in a group of 100 unselected patients surgically treated for uterine prolapse. Another group of 100 unselected patients treated for uterine leiomyoma was used as a control. Pagetoid dyskeratosis was found in 37 cases (37%) of uterine prolapse and in five cases (5%) of uterine leiomyomas. The lesion is more common in uterine prolapse (p
William J Hogan - One of the best experts on this subject based on the ideXlab platform.
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thrombocytosis diagnostic evaluation thrombotic risk stratification and risk based management strategies
Thrombosis, 2011Co-Authors: Jonathan Bleeker, William J HoganAbstract:Thrombocytosis is a commonly encountered clinical scenario, with a large proportion of cases discovered incidentally. The differential diagnosis for thrombocytosis is broad and the diagnostic Process can be challenging. Thrombocytosis can be spurious, attributed to a Reactive Process or due to clonal disorder. This distinction is important as it carries implications for evaluation, prognosis, and treatment. Clonal thrombocytosis associated with the myeloproliferative neoplasms, especially essential thrombocythemia and polycythemia vera, carries a unique prognostic profile, with a markedly increased risk of thrombosis. This risk is the driving factor behind treatment strategies in these disorders. Clinical trials utilizing targeted therapies in thrombocytosis are ongoing with new therapeutic targets waiting to be explored. This paper will outline the mechanisms underlying thrombocytosis, the diagnostic evaluation of thrombocytosis, complications of thrombocytosis with a special focus on thrombotic risk as well as treatment options for clonal Processes leading to thrombocytosis, including essential thrombocythemia and polycythemia vera.
Paul Merlob - One of the best experts on this subject based on the ideXlab platform.
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Neonatal thrombocytosis following G-CSF treatment
Clinical Toxicology, 2007Co-Authors: Micky Osovsky, Hannah Tamary, Paul MerlobAbstract:Thrombocytosis is defined as an elevetion of the platelet count to more than 500,000/mm3 (). Primary thrombocytosis rarely occurs in the pediatric age group and is usually caused by a clonal bone marrow disorder (). The more common phenomenon is secondary thrombocytosis which is a Reactive Process. lists the main causes of secondary thrombocytosis (). Complications of severe thrombocytosis include bleeding and thromboses. Unless additional risk factors are present, secondary thrombocytosis is not associated with a significant risk of thromboembolic events, regardless of the degree of elevation of the platelet count (). The aim of this case report is to add a new possible cause of neonatal thrombocytosis.
Val-bernal Jf - One of the best experts on this subject based on the ideXlab platform.
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Pagetoid dyskeratosis of the cervix: an incidental histologic finding in uterine prolapse.
The American Journal of Surgical Pathology, 2000Co-Authors: Val-bernal Jf, Garijo Mf, Pinto J, Gómez MsAbstract:Pagetoid dyskeratosis, is considered a Reactive Process in which a small part of the normal population of keratinocytes is induced to proliferate. The lesion is characterized by pale cells resembling those of Paget's disease within the epidermis. These cells have been seen as an incidental finding in a variety of benign papules most commonly located in intertriginous areas. Among the inductors of the lesion, friction is suspected. To the best of our knowledge, these pale cells have not been reported in the cervix. We describe the location of the lesion in the ectocervix and the incidence of this lesion in a group of 100 unselected patients surgically treated for uterine prolapse. Another group of 100 unselected patients treated for uterine leiomyoma was used as a control. Pagetoid dyskeratosis was found in 37 cases (37%) of uterine prolapse and in five cases (5%) of uterine leiomyomas. The lesion is more common in uterine prolapse (p
D.m. Hall - One of the best experts on this subject based on the ideXlab platform.
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A simulation tool for Reactive Process planning and scheduling
Fifth International Conference on FACTORY 2000 - The Technology Exploitation Process, 1997Co-Authors: D.m. HallAbstract:The increasing trend for improved agility in the manufacturing industry has led to a demand for more flexible, powerful and Reactive Process planning and scheduling tools. This naturally requires several aspects of manufacturing systems to be integrated to improve information flow and enable an environment for more rapid and effective decision-making. It is also apparent that Process planning and scheduling are more effectively carried out in conjunction with each other, rather than sequentially, as is traditionally the case. A vital factor in this area is the simulation of Process planning and scheduling scenarios in order to see the effects of potential decisions and to enable more flexible, rapid and accurate decision-making. In the development of a system to facilitate Reactive planning and scheduling, a tool for simulating these scenarios has resulted. This tool illustrates the benefits of flexible Process plans and shows how maximum use can be made of any particular manufacturing system.
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Data collection for Reactive Process planning and scheduling
Fifth International Conference on FACTORY 2000 - The Technology Exploitation Process, 1997Co-Authors: D.m. HallAbstract:Summary form only given. The increasing importance of agility in manufacture has led to a demand for more flexible, powerful and Reactive Process planning and scheduling tools. This requires manufacturing practice to be improved, streamlined and run in parallel. There is a need for a data collection strategy which is simple, uniform and affordable by SMEs, preferably based on standard networking. The work builds upon a previous generation of cell control, but using improved hardware and computer facilities, a more portable and transferable system is under development. When complete, this work will eventually provide a 'toolkit' to enable data capture from almost any manufacturing system. The 'toolkit' will be simple, cheap and will make use of readily available hardware. Once data has been captured it can then be made available in a format where it can be handled by Process planning and scheduling software, also under development in a related project. The research continues to develop the methods and hardware necessary for this modular interfacing approach and will, when concluded, provide a cheap method of data capture, easily accessible and implemented by smaller organisations.
