The Experts below are selected from a list of 123 Experts worldwide ranked by ideXlab platform
I-lung Chien - One of the best experts on this subject based on the ideXlab platform.
-
Combined PReconcentrator/Recovery Column Design for Isopropyl Alcohol Dehydration Process
Industrial & Engineering Chemistry Research, 2007Co-Authors: Saiful Arifin, I-lung ChienAbstract:The design and control of a complete heterogeneous azeotropic distillation column system using cyclohexane (CyH) as entrainer has been presented by Chien et al. (Ind. Eng. Chem. Res. 2004, 43, 2160). In that study, the feed composition to the heterogeneous azeotropic column is assumed to be near the isopropyl alcohol (IPA) and water azeotropic composition (water at 31 mol % in that paper). However, for a typical waste IPA stream in the semiconductor industry where IPA is used as a cleaning agent, this waste stream is more diluted. Taking a typical waste IPA stream with equal molar of IPA and water as an example, design and control of the overall isopropyl alcohol dehydration process will be investigated. The resulting proposed design flow sheet is a two-column system which combines pReconcentrator column and recovery column into a single column. This design adapted from Ryan and Doherty (AIChE J. 1989, 35, 1592) for their ethanol dehydration process not only minimizes the total annual cost but also is ver...
-
combined pReconcentrator recovery column design for isopropyl alcohol dehydration process
Industrial & Engineering Chemistry Research, 2007Co-Authors: Saiful Arifin, I-lung ChienAbstract:The design and control of a complete heterogeneous azeotropic distillation column system using cyclohexane (CyH) as entrainer has been presented by Chien et al. (Ind. Eng. Chem. Res. 2004, 43, 2160). In that study, the feed composition to the heterogeneous azeotropic column is assumed to be near the isopropyl alcohol (IPA) and water azeotropic composition (water at 31 mol % in that paper). However, for a typical waste IPA stream in the semiconductor industry where IPA is used as a cleaning agent, this waste stream is more diluted. Taking a typical waste IPA stream with equal molar of IPA and water as an example, design and control of the overall isopropyl alcohol dehydration process will be investigated. The resulting proposed design flow sheet is a two-column system which combines pReconcentrator column and recovery column into a single column. This design adapted from Ryan and Doherty (AIChE J. 1989, 35, 1592) for their ethanol dehydration process not only minimizes the total annual cost but also is ver...
Saiful Arifin - One of the best experts on this subject based on the ideXlab platform.
-
Combined PReconcentrator/Recovery Column Design for Isopropyl Alcohol Dehydration Process
Industrial & Engineering Chemistry Research, 2007Co-Authors: Saiful Arifin, I-lung ChienAbstract:The design and control of a complete heterogeneous azeotropic distillation column system using cyclohexane (CyH) as entrainer has been presented by Chien et al. (Ind. Eng. Chem. Res. 2004, 43, 2160). In that study, the feed composition to the heterogeneous azeotropic column is assumed to be near the isopropyl alcohol (IPA) and water azeotropic composition (water at 31 mol % in that paper). However, for a typical waste IPA stream in the semiconductor industry where IPA is used as a cleaning agent, this waste stream is more diluted. Taking a typical waste IPA stream with equal molar of IPA and water as an example, design and control of the overall isopropyl alcohol dehydration process will be investigated. The resulting proposed design flow sheet is a two-column system which combines pReconcentrator column and recovery column into a single column. This design adapted from Ryan and Doherty (AIChE J. 1989, 35, 1592) for their ethanol dehydration process not only minimizes the total annual cost but also is ver...
-
combined pReconcentrator recovery column design for isopropyl alcohol dehydration process
Industrial & Engineering Chemistry Research, 2007Co-Authors: Saiful Arifin, I-lung ChienAbstract:The design and control of a complete heterogeneous azeotropic distillation column system using cyclohexane (CyH) as entrainer has been presented by Chien et al. (Ind. Eng. Chem. Res. 2004, 43, 2160). In that study, the feed composition to the heterogeneous azeotropic column is assumed to be near the isopropyl alcohol (IPA) and water azeotropic composition (water at 31 mol % in that paper). However, for a typical waste IPA stream in the semiconductor industry where IPA is used as a cleaning agent, this waste stream is more diluted. Taking a typical waste IPA stream with equal molar of IPA and water as an example, design and control of the overall isopropyl alcohol dehydration process will be investigated. The resulting proposed design flow sheet is a two-column system which combines pReconcentrator column and recovery column into a single column. This design adapted from Ryan and Doherty (AIChE J. 1989, 35, 1592) for their ethanol dehydration process not only minimizes the total annual cost but also is ver...
Jeong Hoon Lee - One of the best experts on this subject based on the ideXlab platform.
-
Microfluidic paper-based sample pReconcentrator by ION concentration polarization
2017 19th International Conference on Solid-State Sensors Actuators and Microsystems (TRANSDUCERS), 2017Co-Authors: Sung Ii Han, Yong Kyoung Yoo, Jun Woo Lee, Dohwan Lee, Cheonjung Kim, Kyungjae Lee, Jeong Hoon LeeAbstract:Microfluidic paper-based analytical devices (μPAD) for molecule pReconcentrator have critical problem in non-specific binding and dispersion of the collected molecules, so there is a limitation to the use of direct body fluid (i.e. serum). To address this problem, we demonstrate molecule preconcentration on paper-based reservoir pReconcentrator by ion concentration polarization (ICP) with minimal addition on paper-based reservoir using an undiluted human serum. The cation selective membrane (i.e., Nafion) is patterned on adhesive tape, and this tape is punching to create sample reservoir and buffer reservoir, and then attached to paper-based reservoir. When an electric field is applied across the Nafion, ICP is initiated to preconcentrate the molecules in the sample paper-based reservoir. As a result, fluorescent dyes (alexa fluor 488) in undiluted human serum sample are preconcentrated up to 5-fold. This result is a major advance in molecule preconcentration using an undiluted body fluid for the growing field of POC diagnostics.
-
Microfluidic paper-based biomolecule pReconcentrator based on ion concentration polarization
Lab on a chip, 2016Co-Authors: Sung Il Han, Kyo Seon Hwang, Rhokyun Kwak, Jeong Hoon LeeAbstract:Microfluidic paper-based analytical devices (μPADs) for molecular detection have great potential in the field of point-of-care diagnostics. Currently, a critical problem being faced by μPADs is improving their detection sensitivity. Various preconcentration processes have been developed, but they still have complicated structures and fabrication processes to integrate into μPADs. To address this issue, we have developed a novel paper-based pReconcentrator utilizing ion concentration polarization (ICP) with minimal addition on lateral-flow paper. The cation selective membrane (i.e., Nafion) is patterned on adhesive tape, and this tape is then attached to paper-based channels. When an electric field is applied across the Nafion, ICP is initiated to preconcentrate the biomolecules in the paper channel. Departing from previous paper-based pReconcentrators, we maintain steady lateral fluid flow with the separated Nafion layer; as a result, fluorescent dyes and proteins (FITC–albumin and bovine serum albumin) are continuously delivered to the preconcentration zone, achieving high preconcentration performance up to 1000-fold. In addition, we demonstrate that the Nafion-patterned tape can be integrated with various geometries (multiplexed pReconcentrator) and platforms (string and polymer microfluidic channel). This work would facilitate integration of various ICP devices, including pReconcentrators, pH/concentration modulators, and micro mixers, with steady lateral flows in paper-based platforms.
C.s. Woo - One of the best experts on this subject based on the ideXlab platform.
-
Detection of airborne cocaine and heroin by high-throughput liquid-absorption preconcentration and liquid chromatography—electrochemical detection
Journal of Chromatography A, 1993Co-Authors: Solomon Zaromb, J. Alcaraz, Daniel B. Lawson, C.s. WooAbstract:Abstract A high-throughput liquid-absorption pReconcentrator (HTLAP) for rapid and/or ultrasensitive detection and analysis of trace contaminants samples air at a rate of 600–700 1/min and collects analytes from vapors or aerosols at an efficiency of 40–60% into a small volume of liquid absorbent dripping at a rate of 0.1–2 ml/min. These features combine to reduce the lower detection limit (LDL) of available analytical instrumentation by a factor of > 1000 and/or to permit faster sampling and far more rapid on-site air monitoring than were previously practicable. LDLs of ca. 1: 1013 (v/v) of alkaloids have been achieved with LC and electrochemical detection. The HTLAP is directly adaptable to most liquid-phase analysers. The small rate of liquid collection is also compatible with available interfaces to mass spectrometers. Moreover, the HTLAP permits detection and quantitation of polar or highly reactive compounds that cannot be readily analyzed by conventional preconcentration and GC.
-
High-throughput liquid-absorption air and aerosol sampler
1991Co-Authors: Solomon Zaromb, J. Alcaraz, D. Lawson, K.c. Picel, C.s. WooAbstract:A high-throughput liquid-absorption pReconcentrator (HTLAP) has been developed for rapid and/or ultrasensitive detection and analysis of trace air contaminants. Its advantages result from (a) a high air- sampling rate ({approximately}1 m{sup 3}/min), (b) an appreciable analyte collection efficiency (30--60%) for both vapors and aerosols, and (c) a small volume of liquid absorbent (collected at a rate of 0. 1--2 mL/min), all of which features combine to reduce the LDL (lower detection limit) of available analytical instrumentation by a factor of >1000 and/or to permit faster sampling and far more rapid on-site air monitoring than were previously practicable. LDLs of {approximately}1:10{sup 13} by volume of alkaloids have been achieved with liquid chromatography and electrochemical detection. The HTLAP is directly adaptable to most liquid-phase analyzers. The small rate of liquid collection is also compatible with available interfaces to mass spectrometers. Moreover, the HTLAP permits detection and quantitation of compounds that cannot be readily analyzed by conventional preconcentration and gas chromatography, e.g., polar or highly reactive analytes, such as primary aromatic amines or hydrazines. High selectivity and/or stabilization of labile of reactive analytes, or entrapment of volatile analytes, may be effected through a proper choice of liquid absorbent. 8 refs.
Yafeng Guan - One of the best experts on this subject based on the ideXlab platform.
-
colorimetric determination of copper ii ions by filtration on sol gel membrane doped with diphenylcarbazide
Talanta, 2011Co-Authors: Liang Feng, Yue Zhang, Liying Wen, Zheng Shen, Yafeng GuanAbstract:A simple and sensitive colorimetric method for the determination of trace copper(II) ions in aqueous solution has been developed using diphenylcarbazide (DPC) immobilized sol–gel matrices. To enhance the odds of chelating interactions between copper(II) ions and DPC, a peristaltic pump was utilized to drive copper(II) ions solution pass through the cellulose acetate/nitrate membrane, which was coated with DPC immobilized sol–gel matrices. The membrane was sandwiched in a home-made flow cell. The porous silica matrix serves as a pReconcentrator, and enriches the trace copper(II) ions. Meanwhile, the filtration increases the chelating interaction probability between copper(II) ions and DPC, thereby improves the sensitivity significantly. After the formation of purple complex compound, the color changes of the DPC immobilized sol–gel membrane were recorded using a flatbed scanner. The images were digitized, and the red (R), green (G), and blue (B) values were investigated. The colorimetric method provides a rapid and reliable determination of trace copper(II) ions with a detection limit as low as 0.16M and a kinetic range up to 1.6M in neutral medium. Moreover, the method shows good selectivity, and the color changes of the DPC immobilized sol–gel membranes are remarkable for the copper(II) ions detection even in the presence of other metal ions. © 2011 Elsevier B.V. All rights reserved.
-
Colorimetric determination of copper(II) ions by filtration on sol–gel membrane doped with diphenylcarbazide
Talanta, 2011Co-Authors: Liang Feng, Yue Zhang, Liying Wen, Zheng Shen, Yafeng GuanAbstract:A simple and sensitive colorimetric method for the determination of trace copper(II) ions in aqueous solution has been developed using diphenylcarbazide (DPC) immobilized sol–gel matrices. To enhance the odds of chelating interactions between copper(II) ions and DPC, a peristaltic pump was utilized to drive copper(II) ions solution pass through the cellulose acetate/nitrate membrane, which was coated with DPC immobilized sol–gel matrices. The membrane was sandwiched in a home-made flow cell. The porous silica matrix serves as a pReconcentrator, and enriches the trace copper(II) ions. Meanwhile, the filtration increases the chelating interaction probability between copper(II) ions and DPC, thereby improves the sensitivity significantly. After the formation of purple complex compound, the color changes of the DPC immobilized sol–gel membrane were recorded using a flatbed scanner. The images were digitized, and the red (R), green (G), and blue (B) values were investigated. The colorimetric method provides a rapid and reliable determination of trace copper(II) ions with a detection limit as low as 0.16M and a kinetic range up to 1.6M in neutral medium. Moreover, the method shows good selectivity, and the color changes of the DPC immobilized sol–gel membranes are remarkable for the copper(II) ions detection even in the presence of other metal ions. © 2011 Elsevier B.V. All rights reserved.