The Experts below are selected from a list of 38574 Experts worldwide ranked by ideXlab platform

Nili Zafrir - One of the best experts on this subject based on the ideXlab platform.

  • angiographic correlation of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Ariel Gutstein, Alejandro Solodky, Israel Mats, Roman Navzorov, Ran Kornowski, Nili Zafrir
    Abstract:

    We previously described the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium (Tc-99m) activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to assess the accuracy of this technique by correlating the findings with coronary angiography. Of 290 patients who underwent MPI-gated SPECT using a half dose of Tc-99m sestamibi and OSEM-RR Software in 2010-2012 at a tertiary medical center, 62 were referred for invasive coronary angiography within 90 days and formed the study group. Ischemia was defined as a summed difference score (SDS) of >3 on the MPI scan. Luminal stenosis of ≥70% on invasive coronary angiography served as the reference. Mean Tc-99m activity per study was 23.9 ± 11.5 mCi and mean effective radiation dose was 7.2 ± 3.4 mSv. MPI revealed no abnormalities in 10 patients (16.2%), myocardial infarction only in 8 patients (12.9%), and ischemia in 44 patients (71.1%). Overall sensitivity, specificity, and positive and negative predictive values for MPI compared to invasive angiography were 89.1%, 75.0%, 91.1%, and 70.5%, respectively. MPI SPECT performed with a half dose of Tc-99m and OSEM-RR image processing correlates well with invasive angiography. (J Nucl Cardiol 2013)

  • feasibility of myocardial perfusion imaging with half the radiation dose in obese patients using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Tamir Bental, Yosef Hassid
    Abstract:

    We previously described the feasibility of myocardial perfusion imaging (MPI) with nearly half the radiation dose using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to determine if the findings can be expanded to obese patients. Fifty obese patients (>100 kg) referred for MPI underwent stress-rest or rest-stress studies with a half dose of Tc-99m sestamibi in a 1-day protocol using OSEM-RR processing. Image quality and clinical results were compared with matched patients (by age, sex, weight, presence/probability of coronary artery disease) evaluated with standard “full-dose” Tc-99m sestamibi, mostly in a 2-day protocol. Dose activities were adjusted individually by weight. Mean Tc-99m activity was 33.4 ± 13.9 mCi in the half-dose group and 60 ± 10 mCi in the full-dose group (P < .0001). Respective mean effective doses per study were 10 ± 4 and 18 ± 3 mSv (P < .0001). Overall image quality was good-to-excellent in 94% of the half-dose group and 80% of the full-dose group (P < .045). There was no between-group difference in rate or size of ischemia or infarction, except for stress left ventricular ejection fraction. MPI with half the radiation dose is feasible in obese patients. Image quality is better than for full-dose MPI, and the procedure can be performed in 1 day.

  • feasibility of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2012
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Roman Nevzorov, Alexander Battler
    Abstract:

    Objective This study sought to assess the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR), an iterative reconstruction Software developed to improve count statistics and acquisition time.

Israel Mats - One of the best experts on this subject based on the ideXlab platform.

  • angiographic correlation of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Ariel Gutstein, Alejandro Solodky, Israel Mats, Roman Navzorov, Ran Kornowski, Nili Zafrir
    Abstract:

    We previously described the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium (Tc-99m) activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to assess the accuracy of this technique by correlating the findings with coronary angiography. Of 290 patients who underwent MPI-gated SPECT using a half dose of Tc-99m sestamibi and OSEM-RR Software in 2010-2012 at a tertiary medical center, 62 were referred for invasive coronary angiography within 90 days and formed the study group. Ischemia was defined as a summed difference score (SDS) of >3 on the MPI scan. Luminal stenosis of ≥70% on invasive coronary angiography served as the reference. Mean Tc-99m activity per study was 23.9 ± 11.5 mCi and mean effective radiation dose was 7.2 ± 3.4 mSv. MPI revealed no abnormalities in 10 patients (16.2%), myocardial infarction only in 8 patients (12.9%), and ischemia in 44 patients (71.1%). Overall sensitivity, specificity, and positive and negative predictive values for MPI compared to invasive angiography were 89.1%, 75.0%, 91.1%, and 70.5%, respectively. MPI SPECT performed with a half dose of Tc-99m and OSEM-RR image processing correlates well with invasive angiography. (J Nucl Cardiol 2013)

  • feasibility of myocardial perfusion imaging with half the radiation dose in obese patients using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Tamir Bental, Yosef Hassid
    Abstract:

    We previously described the feasibility of myocardial perfusion imaging (MPI) with nearly half the radiation dose using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to determine if the findings can be expanded to obese patients. Fifty obese patients (>100 kg) referred for MPI underwent stress-rest or rest-stress studies with a half dose of Tc-99m sestamibi in a 1-day protocol using OSEM-RR processing. Image quality and clinical results were compared with matched patients (by age, sex, weight, presence/probability of coronary artery disease) evaluated with standard “full-dose” Tc-99m sestamibi, mostly in a 2-day protocol. Dose activities were adjusted individually by weight. Mean Tc-99m activity was 33.4 ± 13.9 mCi in the half-dose group and 60 ± 10 mCi in the full-dose group (P < .0001). Respective mean effective doses per study were 10 ± 4 and 18 ± 3 mSv (P < .0001). Overall image quality was good-to-excellent in 94% of the half-dose group and 80% of the full-dose group (P < .045). There was no between-group difference in rate or size of ischemia or infarction, except for stress left ventricular ejection fraction. MPI with half the radiation dose is feasible in obese patients. Image quality is better than for full-dose MPI, and the procedure can be performed in 1 day.

  • feasibility of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2012
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Roman Nevzorov, Alexander Battler
    Abstract:

    Objective This study sought to assess the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR), an iterative reconstruction Software developed to improve count statistics and acquisition time.

Alejandro Solodky - One of the best experts on this subject based on the ideXlab platform.

  • angiographic correlation of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Ariel Gutstein, Alejandro Solodky, Israel Mats, Roman Navzorov, Ran Kornowski, Nili Zafrir
    Abstract:

    We previously described the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium (Tc-99m) activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to assess the accuracy of this technique by correlating the findings with coronary angiography. Of 290 patients who underwent MPI-gated SPECT using a half dose of Tc-99m sestamibi and OSEM-RR Software in 2010-2012 at a tertiary medical center, 62 were referred for invasive coronary angiography within 90 days and formed the study group. Ischemia was defined as a summed difference score (SDS) of >3 on the MPI scan. Luminal stenosis of ≥70% on invasive coronary angiography served as the reference. Mean Tc-99m activity per study was 23.9 ± 11.5 mCi and mean effective radiation dose was 7.2 ± 3.4 mSv. MPI revealed no abnormalities in 10 patients (16.2%), myocardial infarction only in 8 patients (12.9%), and ischemia in 44 patients (71.1%). Overall sensitivity, specificity, and positive and negative predictive values for MPI compared to invasive angiography were 89.1%, 75.0%, 91.1%, and 70.5%, respectively. MPI SPECT performed with a half dose of Tc-99m and OSEM-RR image processing correlates well with invasive angiography. (J Nucl Cardiol 2013)

  • feasibility of myocardial perfusion imaging with half the radiation dose in obese patients using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Tamir Bental, Yosef Hassid
    Abstract:

    We previously described the feasibility of myocardial perfusion imaging (MPI) with nearly half the radiation dose using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to determine if the findings can be expanded to obese patients. Fifty obese patients (>100 kg) referred for MPI underwent stress-rest or rest-stress studies with a half dose of Tc-99m sestamibi in a 1-day protocol using OSEM-RR processing. Image quality and clinical results were compared with matched patients (by age, sex, weight, presence/probability of coronary artery disease) evaluated with standard “full-dose” Tc-99m sestamibi, mostly in a 2-day protocol. Dose activities were adjusted individually by weight. Mean Tc-99m activity was 33.4 ± 13.9 mCi in the half-dose group and 60 ± 10 mCi in the full-dose group (P < .0001). Respective mean effective doses per study were 10 ± 4 and 18 ± 3 mSv (P < .0001). Overall image quality was good-to-excellent in 94% of the half-dose group and 80% of the full-dose group (P < .045). There was no between-group difference in rate or size of ischemia or infarction, except for stress left ventricular ejection fraction. MPI with half the radiation dose is feasible in obese patients. Image quality is better than for full-dose MPI, and the procedure can be performed in 1 day.

  • feasibility of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2012
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Roman Nevzorov, Alexander Battler
    Abstract:

    Objective This study sought to assess the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR), an iterative reconstruction Software developed to improve count statistics and acquisition time.

Alexander Battler - One of the best experts on this subject based on the ideXlab platform.

Avi Benshlomo - One of the best experts on this subject based on the ideXlab platform.

  • feasibility of myocardial perfusion imaging with half the radiation dose in obese patients using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2013
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Tamir Bental, Yosef Hassid
    Abstract:

    We previously described the feasibility of myocardial perfusion imaging (MPI) with nearly half the radiation dose using ordered-subset expectation maximization with resolution Recovery (OSEM-RR) processing. This study sought to determine if the findings can be expanded to obese patients. Fifty obese patients (>100 kg) referred for MPI underwent stress-rest or rest-stress studies with a half dose of Tc-99m sestamibi in a 1-day protocol using OSEM-RR processing. Image quality and clinical results were compared with matched patients (by age, sex, weight, presence/probability of coronary artery disease) evaluated with standard “full-dose” Tc-99m sestamibi, mostly in a 2-day protocol. Dose activities were adjusted individually by weight. Mean Tc-99m activity was 33.4 ± 13.9 mCi in the half-dose group and 60 ± 10 mCi in the full-dose group (P < .0001). Respective mean effective doses per study were 10 ± 4 and 18 ± 3 mSv (P < .0001). Overall image quality was good-to-excellent in 94% of the half-dose group and 80% of the full-dose group (P < .045). There was no between-group difference in rate or size of ischemia or infarction, except for stress left ventricular ejection fraction. MPI with half the radiation dose is feasible in obese patients. Image quality is better than for full-dose MPI, and the procedure can be performed in 1 day.

  • feasibility of myocardial perfusion imaging with half the radiation dose using ordered subset expectation maximization with resolution Recovery Software
    Journal of Nuclear Cardiology, 2012
    Co-Authors: Nili Zafrir, Alejandro Solodky, Avi Benshlomo, Israel Mats, Roman Nevzorov, Alexander Battler
    Abstract:

    Objective This study sought to assess the feasibility of performing myocardial perfusion imaging (MPI) with half the technetium activity using ordered-subset expectation maximization with resolution Recovery (OSEM-RR), an iterative reconstruction Software developed to improve count statistics and acquisition time.