The Experts below are selected from a list of 306 Experts worldwide ranked by ideXlab platform
Rosa Burgers - One of the best experts on this subject based on the ideXlab platform.
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Rectal examination in children digital versus transabdominal ultrasound
The Journal of Urology, 2013Co-Authors: Rosa Burgers, Tom P V M De Jong, Marc A. BenningaAbstract:Purpose: We investigate 2 diagnostic tests to assess the Rectal filling state.Materials and Methods: The Rectal filling state was assessed with transabdominal ultrasound or with digital Rectal examination by 2 independent investigators in children with urological problems before a scheduled diagnostic or surgical urological procedure. A dilated rectum filled with stool or large amounts of (usually) hard stool were both considered as a Rectal fecal mass. All investigations were performed with the patient under general anesthesia. The kappa test was used to evaluate agreement between transabdominal ultrasound and digital Rectal examination.Results: A total of 84 children (54 boys) with a median (p25–p75) age of 9.0 years (6.4–11) were eligible candidates. A Rectal mass was found on transabdominal ultrasound and digital Rectal examination in 32% and 41% of all children, respectively, with agreement between the 2 tests in 82.5%. Cohen's kappa showed good agreement of 0.62 (95% CI 0.45–0.79) between transabdom...
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899 Rectal Examination in Children: Digital Versus Transabdominal Ultrasound
Gastroenterology, 2012Co-Authors: Rosa Burgers, Tom P V M De Jong, Marc A. BenningaAbstract:Purpose: We investigate 2 diagnostic tests to assess the Rectal filling state. Materials and Methods: The Rectal filling state was assessed with transabdominal ultrasound or with digital Rectal examination by 2 independent investigators in children with urological problems before a scheduled diagnostic or surgical urological procedure. A dilated rectum filled with stool or large amounts of (usually) hard stool were both considered as a Rectal fecal mass. All investigations were performed with the patient under general anesthesia. The kappa test was used to evaluate agreement between transabdominal ultrasound and digital Rectal examination. Results: A total of 84 children (54 boys) with a median (p25‐p75) age of 9.0 years (6.4‐11) were eligible candidates. A Rectal mass was found on transabdominal ultrasound and digital Rectal examination in 32% and 41% of all children, respectively, with agreement between the 2 tests in 82.5%. Cohen’s kappa showed good agreement of 0.62 (95% CI 0.45‐0.79) between transabdominal ultrasound and digital Rectal examination. The median (IQR) diameter of the rectum was 3.3 cm (2.8‐3.9) in children with a full rectum, and 2.5 cm (1.8‐2.8) and 2.0 cm (1.5‐2.2) in patients with a half filled and empty rectum, respectively. Conclusions: Transabdominal ultrasound is a noninvasive and reliable alternative to assess the Rectal filling state, and might replace digital Rectal examination in the evaluation of children with constipation.
Marc A. Benninga - One of the best experts on this subject based on the ideXlab platform.
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Rectal examination in children digital versus transabdominal ultrasound
The Journal of Urology, 2013Co-Authors: Rosa Burgers, Tom P V M De Jong, Marc A. BenningaAbstract:Purpose: We investigate 2 diagnostic tests to assess the Rectal filling state.Materials and Methods: The Rectal filling state was assessed with transabdominal ultrasound or with digital Rectal examination by 2 independent investigators in children with urological problems before a scheduled diagnostic or surgical urological procedure. A dilated rectum filled with stool or large amounts of (usually) hard stool were both considered as a Rectal fecal mass. All investigations were performed with the patient under general anesthesia. The kappa test was used to evaluate agreement between transabdominal ultrasound and digital Rectal examination.Results: A total of 84 children (54 boys) with a median (p25–p75) age of 9.0 years (6.4–11) were eligible candidates. A Rectal mass was found on transabdominal ultrasound and digital Rectal examination in 32% and 41% of all children, respectively, with agreement between the 2 tests in 82.5%. Cohen's kappa showed good agreement of 0.62 (95% CI 0.45–0.79) between transabdom...
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899 Rectal Examination in Children: Digital Versus Transabdominal Ultrasound
Gastroenterology, 2012Co-Authors: Rosa Burgers, Tom P V M De Jong, Marc A. BenningaAbstract:Purpose: We investigate 2 diagnostic tests to assess the Rectal filling state. Materials and Methods: The Rectal filling state was assessed with transabdominal ultrasound or with digital Rectal examination by 2 independent investigators in children with urological problems before a scheduled diagnostic or surgical urological procedure. A dilated rectum filled with stool or large amounts of (usually) hard stool were both considered as a Rectal fecal mass. All investigations were performed with the patient under general anesthesia. The kappa test was used to evaluate agreement between transabdominal ultrasound and digital Rectal examination. Results: A total of 84 children (54 boys) with a median (p25‐p75) age of 9.0 years (6.4‐11) were eligible candidates. A Rectal mass was found on transabdominal ultrasound and digital Rectal examination in 32% and 41% of all children, respectively, with agreement between the 2 tests in 82.5%. Cohen’s kappa showed good agreement of 0.62 (95% CI 0.45‐0.79) between transabdominal ultrasound and digital Rectal examination. The median (IQR) diameter of the rectum was 3.3 cm (2.8‐3.9) in children with a full rectum, and 2.5 cm (1.8‐2.8) and 2.0 cm (1.5‐2.2) in patients with a half filled and empty rectum, respectively. Conclusions: Transabdominal ultrasound is a noninvasive and reliable alternative to assess the Rectal filling state, and might replace digital Rectal examination in the evaluation of children with constipation.
Tom P V M De Jong - One of the best experts on this subject based on the ideXlab platform.
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Rectal examination in children digital versus transabdominal ultrasound
The Journal of Urology, 2013Co-Authors: Rosa Burgers, Tom P V M De Jong, Marc A. BenningaAbstract:Purpose: We investigate 2 diagnostic tests to assess the Rectal filling state.Materials and Methods: The Rectal filling state was assessed with transabdominal ultrasound or with digital Rectal examination by 2 independent investigators in children with urological problems before a scheduled diagnostic or surgical urological procedure. A dilated rectum filled with stool or large amounts of (usually) hard stool were both considered as a Rectal fecal mass. All investigations were performed with the patient under general anesthesia. The kappa test was used to evaluate agreement between transabdominal ultrasound and digital Rectal examination.Results: A total of 84 children (54 boys) with a median (p25–p75) age of 9.0 years (6.4–11) were eligible candidates. A Rectal mass was found on transabdominal ultrasound and digital Rectal examination in 32% and 41% of all children, respectively, with agreement between the 2 tests in 82.5%. Cohen's kappa showed good agreement of 0.62 (95% CI 0.45–0.79) between transabdom...
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899 Rectal Examination in Children: Digital Versus Transabdominal Ultrasound
Gastroenterology, 2012Co-Authors: Rosa Burgers, Tom P V M De Jong, Marc A. BenningaAbstract:Purpose: We investigate 2 diagnostic tests to assess the Rectal filling state. Materials and Methods: The Rectal filling state was assessed with transabdominal ultrasound or with digital Rectal examination by 2 independent investigators in children with urological problems before a scheduled diagnostic or surgical urological procedure. A dilated rectum filled with stool or large amounts of (usually) hard stool were both considered as a Rectal fecal mass. All investigations were performed with the patient under general anesthesia. The kappa test was used to evaluate agreement between transabdominal ultrasound and digital Rectal examination. Results: A total of 84 children (54 boys) with a median (p25‐p75) age of 9.0 years (6.4‐11) were eligible candidates. A Rectal mass was found on transabdominal ultrasound and digital Rectal examination in 32% and 41% of all children, respectively, with agreement between the 2 tests in 82.5%. Cohen’s kappa showed good agreement of 0.62 (95% CI 0.45‐0.79) between transabdominal ultrasound and digital Rectal examination. The median (IQR) diameter of the rectum was 3.3 cm (2.8‐3.9) in children with a full rectum, and 2.5 cm (1.8‐2.8) and 2.0 cm (1.5‐2.2) in patients with a half filled and empty rectum, respectively. Conclusions: Transabdominal ultrasound is a noninvasive and reliable alternative to assess the Rectal filling state, and might replace digital Rectal examination in the evaluation of children with constipation.
Bruce L Dalkin - One of the best experts on this subject based on the ideXlab platform.
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Comparison of Digital Rectal Examination and Serum Prostate Specific Antigen in the Early Detection of Prostate Cancer: Results of a Multicenter Clinical Trial of 6,630 Men.
The Journal of urology, 2016Co-Authors: William J Catalona, Jerome P Richie, Frederick R Ahmann, Mliss A Hudson, Peter T Scardino, Jean B Dekernion, Timothy L Ratliff, Louis R. Kavoussi, Robert C. Flanigan, Bruce L DalkinAbstract:To compare the efficacy of digital Rectal examination and serum prostate specific antigen (PSA) in the early detection of prostate cancer, we conducted a prospective clinical trial at 6 university centers of 6,630 male volunteers 50 years old or older who underwent PSA determination (Hybritech Tandom-E or Tandem-R assays) and digital Rectal examination. Quadrant biopsies were performed if the PSA level was greater than 4 μg./l. or digital Rectal examination was suspicious, even if transRectal ultrasonography revealed no areas suspicious for cancer. The results showed that 15% of the men had a PSA level of greater than 4 μg./l., 15% had a suspicious digital Rectal examination and 26% had suspicious findings on either or both tests. Of 1,167 biopsies performed cancer was detected in 264. PSA detected significantly more tumors (82%, 216 of 264 cancers) than digital Rectal examination (55%, 146 of 264, p = 0.001). The cancer detection rate was 3.2% for digital Rectal examination, 4.6% for PSA and 5.8% for the 2 methods combined. Positive predictive value was 32% for PSA and 21% for digital Rectal examination. Of 160 patients who underwent radical prostatectomy and pathological staging 114 (71%) had organ confined cancer: PSA detected 85 (75%) and digital Rectal examination detected 64 (56%, p = 0.003). Use of the 2 methods in combination increased detection of organ confined disease by 78% (50 of 64 cases) over digital Rectal examination alone. If the performance of a biopsy would have required suspicious transRectal ultrasonography findings, nearly 40% of the tumors would have been missed. We conclude that the use of PSA in conjunction with digital Rectal examination enhances early prostate cancer detection. Prostatic biopsy should be considered if either the PSA level is greater than 4 μg./l. or digital Rectal examination is suspicious for cancer, even in the absence of abnormal transRectal ultrasonography findings.
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accuracy of digital Rectal examination and transRectal ultrasonography in localizing prostate cancer
The Journal of Urology, 1994Co-Authors: Robert C. Flanigan, William J Catalona, Jerome P Richie, Frederick R Ahmann, Mliss A Hudson, Peter T Scardino, Jean B Dekernion, Timothy L Ratliff, Louis R. Kavoussi, Bruce L DalkinAbstract:AbstractNot all prostate cancers are sonographically hypoechoic or palpable on digital Rectal examination, and suspicious areas on transRectal prostatic ultrasonography or digital Rectal examination often are not cancer. We present quadrant biopsy results from a multicenter prostate cancer screening study in which men were evaluated with prostate specific antigen (PSA) and digital Rectal examination. If the PSA level was elevated (greater than 4.0 ng./ml., Hybritech Tandem assay) or digital Rectal examination was suspicious quadrant biopsies were performed. Biopsy specimens were labeled separately, and histological findings were correlated by quadrant with the findings on ultrasonography and digital Rectal examination. Of the 6,630 subjects enrolled into the study 16% were biopsied. Of 1,002 quadrants that were suspicious on digital Rectal examination 110 (11%) had cancer, while 308 of 418 quadrants containing cancer (74%) were not suspicious on digital Rectal examination. Of 855 quadrants that were sonog...
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Accuracy of digital Rectal examination and transRectal ultrasonography in localizing prostate cancer.
The Journal of urology, 1994Co-Authors: Robert C. Flanigan, William J Catalona, Jerome P Richie, Frederick R Ahmann, Mliss A Hudson, Peter T Scardino, Jean B Dekernion, Timothy L Ratliff, Louis R. Kavoussi, Bruce L DalkinAbstract:Not all prostate cancers are sonographically hypoechoic or palpable on digital Rectal examination, and suspicious areas on transRectal prostatic ultrasonography or digital Rectal examination often are not cancer. We present quadrant biopsy results from a multicenter prostate cancer screening study in which men were evaluated with prostate specific antigen (PSA) and digital Rectal examination. If the PSA level was elevated (greater than 4.0 ng./ml., Hybritech Tandem assay) or digital Rectal examination was suspicious quadrant biopsies were performed. Biopsy specimens were labeled separately, and histological findings were correlated by quadrant with the findings on ultrasonography and digital Rectal examination. Of the 6,630 subjects enrolled into the study 16% were biopsied. Of 1,002 quadrants that were suspicious on digital Rectal examination 110 (11%) had cancer, while 308 of 418 quadrants containing cancer (74%) were not suspicious on digital Rectal examination. Of 855 quadrants that were sonographically suspicious 153 (18%) had cancer, while 282 of 435 quadrants containing cancer (65%) were not sonographically suspicious. Of 225 patients with cancer 137 (61%) would have been missed if only the exact site of the palpable induration had been biopsied. Of 251 patients with cancer 131 (52%) would have been missed if only the exact site of the hypoechoic lesion had been biopsied. We conclude that digital Rectal examination and transRectal ultrasonography have limited accuracy in identifying and localizing prostate cancer. Our study emphasizes the importance of obtaining systematic biopsies if the PSA level is elevated, even in the absence of digital Rectal examination or ultrasound anomalies.
Michael K Brawer - One of the best experts on this subject based on the ideXlab platform.
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diagnosis of prostatic carcinoma the yield of serum prostate specific antigen digital Rectal examination and transRectal ultrasonography
The Journal of Urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:AbstractThree tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital Rectal examination and transRectal ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital Rectal examination or transRectal ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus transRectal ultrasonography and PSA plus digital Rectal examination were superior to digital Rectal examination plus transRectal ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated Rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital Rectal examination and PSA level of ...
