The Experts below are selected from a list of 18015 Experts worldwide ranked by ideXlab platform

M. Seker - One of the best experts on this subject based on the ideXlab platform.

Chen Dao-d - One of the best experts on this subject based on the ideXlab platform.

  • Sphincter-preserving surgery in patients with lower third Rectum Cancer
    Chinese Journal of Gastrointestinal Surgery, 2003
    Co-Authors: Chen Dao-d
    Abstract:

    Objective To choose reasonable surgical methods to treat the patients with lower third Rectum Cancer. Methods Forty-four patients with rectal tumors located 5 and 7 cm from the anal verge were surgically treated, including modified coloanal anastomosis (group A) in 21 cases and anterior excision using stapling technique (group B) in 23 cases. The outcomes were compared between the two groups. Results Tumor residual in the distal rectal stump was found in 2 cases in group B, while no case in group A. The mean length of resected Rectum from the lower border of the tumor was (2. 81±0. 35)cm in group A, longer than (1.73±0. 42)cm in group B( t = 9. 083, P 0. 001). Local recurrence occurred in none case in group A and 4 cases in group B. The local recurrence rate in group B was higher than that in group A(x2 = 4.234, P = 0. 04) . In the early postoperative period, bowel function in group A was not satisfied, but improved within half a year. The patients with anterior excision had better bowel function. Conclusions As for the patients with low rectal Cancer, reasonable sphincter-saving techniqnes, including modified coloanal anastomosis and anterior excision with stapling technique, should be chosen according to sex, weight, depth and width of pelvis of the patients, differentiation and infiltration of tumors.

Liu Meng-zhon - One of the best experts on this subject based on the ideXlab platform.

  • Dosimetric comparison between preoperative five-field intensity modulated radiotherapy and volumetric modulated arc therapy in the treatment of Rectum Cancer
    Chinese clinical oncology, 2012
    Co-Authors: Liu Meng-zhon
    Abstract:

    Objective To investigate the dosimetric comparison between preoperative five-field intensity modulated radiotherapy(5F-IMRT) and volumetric modulated arc therapy(VMAT) in the Rectum Cancer patients with concurrent chemotherapy and radiotherapy.Methods With the application of CMS monaco systems(V2.0,Sweden),5F-IMRT and VMAT plans were simulated in 23 Rectum Cancer patients with preoperative concurrent chemoradiotherapy.The dose characteristic of target volume was evaluated and the dose-volume relationship of small bowel,bladder and bilateral femoral head was compared.Results The CI was similar between the 5F-IMRT(0.810±0.043) and VMAT plans(0.822±0.062),which could satisfy 95% of prescribed dose for covered PTV.The HI of the prescribed dose to GTV(1.052±0.019 vs.1.037±0.008),CTV(1.063±0.016 vs.1.047±0.008) and PTV(1.075±0.020 vs.1.072±0.018) in the two kinds of plans was similar too.There was no significant difference for the key parameters(D5,Dmin,Dmean and Dmax) of risk organs such as intestine,bladder and femoral head in the two plans(P0.05).There was no significant difference for the key parameters of irradiated volume such as V20,V30,V40 and V50 of risk organs between the 5F-IMRT and VMAT plans(P0.05).Conclusion VMAT plans was as good as 5F-IMRT in the prescribed dose for the target volume,and risk organs such as intestine,bladder and femoral head could be well protected.

Uriel Martinez - One of the best experts on this subject based on the ideXlab platform.

  • Local Recurrence in Patients with Upper Third Rectum Cancer Treated with Surgery Alone Compared with Surgery Plus Chemoradiotherapy
    Radiotherapy and Clinical Oncology, 2020
    Co-Authors: Beatriz Mota, David Rayas, Jesús Sansón, Manuel Martínez, Uriel Martinez
    Abstract:

    Background: Colorectal Cancer is the third most common neoplasm in Mexico, rectal Cancer is the 16th most common neoplasm [1]. Due to the different behavior and prognostic factors of locally advance disease, manage should be tailored by a multidisciplinary approach. In tumors that rise in the upper third Rectum Cancer scenario there are no studies comparing the oncological results of multimodal treatment vs surgery alone. Objective: To compare the disease-free survival in patients with upper third rectal Cancer treated with surgery alone vs multimodal treatment. Material and Methods: We conducted a descriptive, retrospective, longitudinal study using an historical cohort. Analysis was based from the information in patient`s records from diagnosed with Cancer of the upper third Rectum from 2011 to 2016. All patients with diagnosis of upper third Rectum Cancer were set in to two groups according to the treatment modality recited: Surgery alone and neoadjuvant chemotherapy. The records of patients diagnosed with Cancer of the upper third Rectum were reviewed and divided into two groups: with and without neoadjuvant chemoradiotherapy, both treated with surgery. Results: A total of 64 patient`s record were eligible, 48 of them were treated with surgery alone and 16 with a multimodal approach. The mean age was 65.5 years in those treated with surgery and 69 in the multimodal management group. The most frequent procedure was anterior resection, 45 cases (70.3%) in the group treated with surgery and 12 cases (18.7%) in the multimodal group. A case of complete pathological response was reported after a follow up of two years. Conclusion: The data suggests that there are no statistically significant differences in the local recurrence and disease-free survival with the use of neoadjuvant chemoradiotherapy.

Sener Cihan - One of the best experts on this subject based on the ideXlab platform.