The Experts below are selected from a list of 55773 Experts worldwide ranked by ideXlab platform
Richard J Millard - One of the best experts on this subject based on the ideXlab platform.
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the accuracy of portable ultrasound scanning in the measurement of Residual urine Volume
The Journal of Urology, 1994Co-Authors: G M Coombes, Richard J MillardAbstract:AbstractThe accuracy of 2 successive models of a portable (2.5kg.) ultrasound unit in determining Residual urine Volumes in 100 patients was assessed. Ultrasound measurements were compared to post-scan bladder Volumes obtained by catheterization and fluoroscopic screening in the same patients. The first ultrasound unit (group 1, 50 patients) showed correlation with Residual Volumes of 0.86 (R2 = 0.73) and a mean difference from the true Residual Volume of 41ml. (95% confidence interval 26 to 55 ml.). The second ultrasound unit (group 2, 50 patients) showed correlation with Residual Volumes of 0.97 (R2 = 0.94) and a mean difference from the true Residual Volume of 24ml. (95% confidence interval 17 to 31ml.). The differences in Volumes were significantly lower with scanner 2 (t = 2.02, p = 0.047). The mean difference between catheter Volume estimate and true bladder Volume was 25ml. (95% confidence interval 16 to 34ml.). The accuracy of the BladderScan BVI 2500+ scanner* is as good as catheter estimations o...
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The accuracy of portable ultrasound scanning in the measurement of Residual urine Volume.
The Journal of urology, 1994Co-Authors: G M Coombes, Richard J MillardAbstract:The accuracy of 2 successive models of a portable (2.5 kg.) ultrasound unit in determining Residual urine Volumes in 100 patients was assessed. Ultrasound measurements were compared to post-scan bladder Volumes obtained by catheterization and fluoroscopic screening in the same patients. The first ultrasound unit (group 1, 50 patients) showed correlation with Residual Volumes of 0.86 (R2 = 0.73) and a mean difference from the true Residual Volume of 41 ml. (95% confidence interval 26 to 55 ml.). The second ultrasound unit (group 2, 50 patients) showed correlation with Residual Volumes of 0.97 (R2 = 0.94) and a mean difference from the true Residual Volume of 24 ml. (95% confidence interval 17 to 31 ml.). The differences in Volumes were significantly lower with scanner 2 (t = 2.02, p = 0.047). The mean difference between catheter Volume estimate and true bladder Volume was 25 ml. (95% confidence interval 16 to 34 ml.). The accuracy of the BladderScan BVI 2500+ scanner is as good as catheter estimations of true Residual Volume and is sufficient to recommend its use as an alternative to catheterization for the determination of Residual urine Volume.
Otto F Barak - One of the best experts on this subject based on the ideXlab platform.
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temporal changes in pulmonary gas exchange efficiency when breath hold diving below Residual Volume
Experimental Physiology, 2021Co-Authors: Alexander Patrician, Andrew T. Lovering, Connor A. Howe, Boris Spajic, Christopher Gasho, Hannah G Caldwell, Tony G Dawkins, Mike Stembridge, Geoff B Coombs, Otto F BarakAbstract:NEW FINDINGS What is the central question of this study? How does deep breath-hold diving impact cardiopulmonary function, both acutely and over the subsequent 2.5 hours post-dive? What is the main finding and its importance? Breath-hold diving, to depths below Residual Volume, is associated with acute impairments in pulmonary gas exchange, which typically resolve within 2.5 hours. These data provide new insight into the behaviour of the lungs and pulmonary vasculature following deep diving. ABSTRACT Breath-hold diving involves highly integrative and extreme physiological responses to both exercise and asphyxia during progressive elevations in hydrostatic pressure. Over two diving training camps (Study 1 and 2), 25 breath-hold divers (recreational to world-champion) performed 66 dives to 57 ± 20 m (range: 18-117 m). Using the deepest dive from each diver, temporal changes in cardiopulmonary function were assessed using non-invasive pulmonary gas exchange (indexed via the O2 deficit), ultrasound B-line scores, lung compliance and pulmonary haemodynamics at baseline and following the dive. Hydrostatically induced lung compression was quantified in Study 2, using spirometry and lung Volume measurement, enabling each dive to be categorized by its Residual Volume (RV)-equivalent depth. From both studies, pulmonary gas exchange inefficiency - defined as an increase in O2 deficit - was related to the depth of the dive (r2 = 0.345; P < 0.001), with dives associated with lung squeeze symptoms exhibiting the greatest deficits. In Study 1, although B-lines doubled from baseline (P = 0.027), cardiac output and pulmonary artery systolic pressure were unchanged post-dive. In Study 2, dives with lung compression to ≤RV had higher O2 deficits at 9 min, compared to dives that did not exceed RV (24 ± 25 vs. 5 ± 8 mmHg; P = 0.021). The physiological significance of a small increase in estimated lung compliance post-dive (via decreased and increased/unaltered airway resistance and reactance, respectively) remains equivocal. Following deep dives, the current study highlights an integrated link between hydrostatically induced lung compression and transient impairments in pulmonary gas exchange efficiency.
G M Coombes - One of the best experts on this subject based on the ideXlab platform.
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the accuracy of portable ultrasound scanning in the measurement of Residual urine Volume
The Journal of Urology, 1994Co-Authors: G M Coombes, Richard J MillardAbstract:AbstractThe accuracy of 2 successive models of a portable (2.5kg.) ultrasound unit in determining Residual urine Volumes in 100 patients was assessed. Ultrasound measurements were compared to post-scan bladder Volumes obtained by catheterization and fluoroscopic screening in the same patients. The first ultrasound unit (group 1, 50 patients) showed correlation with Residual Volumes of 0.86 (R2 = 0.73) and a mean difference from the true Residual Volume of 41ml. (95% confidence interval 26 to 55 ml.). The second ultrasound unit (group 2, 50 patients) showed correlation with Residual Volumes of 0.97 (R2 = 0.94) and a mean difference from the true Residual Volume of 24ml. (95% confidence interval 17 to 31ml.). The differences in Volumes were significantly lower with scanner 2 (t = 2.02, p = 0.047). The mean difference between catheter Volume estimate and true bladder Volume was 25ml. (95% confidence interval 16 to 34ml.). The accuracy of the BladderScan BVI 2500+ scanner* is as good as catheter estimations o...
-
The accuracy of portable ultrasound scanning in the measurement of Residual urine Volume.
The Journal of urology, 1994Co-Authors: G M Coombes, Richard J MillardAbstract:The accuracy of 2 successive models of a portable (2.5 kg.) ultrasound unit in determining Residual urine Volumes in 100 patients was assessed. Ultrasound measurements were compared to post-scan bladder Volumes obtained by catheterization and fluoroscopic screening in the same patients. The first ultrasound unit (group 1, 50 patients) showed correlation with Residual Volumes of 0.86 (R2 = 0.73) and a mean difference from the true Residual Volume of 41 ml. (95% confidence interval 26 to 55 ml.). The second ultrasound unit (group 2, 50 patients) showed correlation with Residual Volumes of 0.97 (R2 = 0.94) and a mean difference from the true Residual Volume of 24 ml. (95% confidence interval 17 to 31 ml.). The differences in Volumes were significantly lower with scanner 2 (t = 2.02, p = 0.047). The mean difference between catheter Volume estimate and true bladder Volume was 25 ml. (95% confidence interval 16 to 34 ml.). The accuracy of the BladderScan BVI 2500+ scanner is as good as catheter estimations of true Residual Volume and is sufficient to recommend its use as an alternative to catheterization for the determination of Residual urine Volume.
Dirkjan Slebos - One of the best experts on this subject based on the ideXlab platform.
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change in dynamic hyperinflation after bronchoscopic lung Volume reduction in patients with emphysema
Lung, 2020Co-Authors: Marlies Van Dijk, Karin Klooster, Jorine E Hartman, Nick Ten H T Hacken, Dirkjan SlebosAbstract:In patients with severe emphysema, dynamic hyperinflation is superimposed on top of already existing static hyperinflation. Static hyperinflation reduces significantly after bronchoscopic lung Volume reduction (BLVR). In this study, we investigated the effect of BLVR compared to standard of care (SoC) on dynamic hyperinflation. Dynamic hyperinflation was induced by a manually paced tachypnea test (MPT) and was defined by change in inspiratory capacity (IC) measured before and after MPT. Static and dynamic hyperinflation measurements were performed both at baseline and 6 months after BLVR with endobronchial valves or coils (treatment group) or SoC (control group). Eighteen patients underwent BLVR (78% female, 57 (43–67) years, FEV1 25(18–37) %predicted, Residual Volume 231 (182–376) %predicted). Thirteen patients received SoC (100% female, 59 (44–74) years, FEV1 25 (19–37) %predicted, Residual Volume 225 (152–279) %predicted. The 6 months median change in dynamic hyperinflation in the treatment group was: + 225 ml (range − 113 to + 803) (p < 0.01) vs 0 ml (− 1067 to + 500) in the control group (p = 0.422). An increase in dynamic hyperinflation was significantly associated with a decrease in Residual Volume (r = − 0.439, p < 0.01). Bronchoscopic lung Volume reduction increases the ability for dynamic hyperinflation in patients with severe emphysema. We propose this is a consequence of improved static hyperinflation.
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Change in Dynamic Hyperinflation After Bronchoscopic Lung Volume Reduction in Patients with Emphysema
Lung, 2020Co-Authors: Marlies Van Dijk, Karin Klooster, Jorine E Hartman, Nick Ten H T Hacken, Dirkjan SlebosAbstract:Background and Purpose In patients with severe emphysema, dynamic hyperinflation is superimposed on top of already existing static hyperinflation. Static hyperinflation reduces significantly after bronchoscopic lung Volume reduction (BLVR). In this study, we investigated the effect of BLVR compared to standard of care (SoC) on dynamic hyperinflation. Methods Dynamic hyperinflation was induced by a manually paced tachypnea test (MPT) and was defined by change in inspiratory capacity (IC) measured before and after MPT. Static and dynamic hyperinflation measurements were performed both at baseline and 6 months after BLVR with endobronchial valves or coils (treatment group) or SoC (control group). Results Eighteen patients underwent BLVR (78% female, 57 (43–67) years, FEV_1 25(18–37) %predicted, Residual Volume 231 (182–376) %predicted). Thirteen patients received SoC (100% female, 59 (44–74) years, FEV_1 25 (19–37) %predicted, Residual Volume 225 (152–279) %predicted. The 6 months median change in dynamic hyperinflation in the treatment group was: + 225 ml (range − 113 to + 803) ( p
Alexander Patrician - One of the best experts on this subject based on the ideXlab platform.
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temporal changes in pulmonary gas exchange efficiency when breath hold diving below Residual Volume
Experimental Physiology, 2021Co-Authors: Alexander Patrician, Andrew T. Lovering, Connor A. Howe, Boris Spajic, Christopher Gasho, Hannah G Caldwell, Tony G Dawkins, Mike Stembridge, Geoff B Coombs, Otto F BarakAbstract:NEW FINDINGS What is the central question of this study? How does deep breath-hold diving impact cardiopulmonary function, both acutely and over the subsequent 2.5 hours post-dive? What is the main finding and its importance? Breath-hold diving, to depths below Residual Volume, is associated with acute impairments in pulmonary gas exchange, which typically resolve within 2.5 hours. These data provide new insight into the behaviour of the lungs and pulmonary vasculature following deep diving. ABSTRACT Breath-hold diving involves highly integrative and extreme physiological responses to both exercise and asphyxia during progressive elevations in hydrostatic pressure. Over two diving training camps (Study 1 and 2), 25 breath-hold divers (recreational to world-champion) performed 66 dives to 57 ± 20 m (range: 18-117 m). Using the deepest dive from each diver, temporal changes in cardiopulmonary function were assessed using non-invasive pulmonary gas exchange (indexed via the O2 deficit), ultrasound B-line scores, lung compliance and pulmonary haemodynamics at baseline and following the dive. Hydrostatically induced lung compression was quantified in Study 2, using spirometry and lung Volume measurement, enabling each dive to be categorized by its Residual Volume (RV)-equivalent depth. From both studies, pulmonary gas exchange inefficiency - defined as an increase in O2 deficit - was related to the depth of the dive (r2 = 0.345; P < 0.001), with dives associated with lung squeeze symptoms exhibiting the greatest deficits. In Study 1, although B-lines doubled from baseline (P = 0.027), cardiac output and pulmonary artery systolic pressure were unchanged post-dive. In Study 2, dives with lung compression to ≤RV had higher O2 deficits at 9 min, compared to dives that did not exceed RV (24 ± 25 vs. 5 ± 8 mmHg; P = 0.021). The physiological significance of a small increase in estimated lung compliance post-dive (via decreased and increased/unaltered airway resistance and reactance, respectively) remains equivocal. Following deep dives, the current study highlights an integrated link between hydrostatically induced lung compression and transient impairments in pulmonary gas exchange efficiency.
