Reticulosis

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Martin Schaller - One of the best experts on this subject based on the ideXlab platform.

  • pagetoid Reticulosis woringer kolopp disease
    Journal Der Deutschen Dermatologischen Gesellschaft, 2009
    Co-Authors: V. Lichte, Annette Geyer, Mathias Mohrle, Kamran Ghoreschi, Gisela Metzler, Martin Röcken, Martin Schaller
    Abstract:

    Summary Pagetoid Reticulosis (Woringer-Kolopp disease) is a rare subtype of cutaneous CD8-positive T-cell lymphoma. A 41-year-old man presented with a 7-year history with a slowly progressive erythematous plaque on his right buttocks. With the working diagnosis of psoriasis, he was treated with topical corticosteroids which produced no improvement. Histological examination showed an epidermotropic T-cell lymphoma with predominance of CD8- vs.CD4-positive lymphocytes. Based on the clinical picture and the histological findings, we diagnosed pagetoid Reticulosis. Excision of the plaque and cream PUVA photo-chemotherapy produced long-term remission.

  • pagetoid Reticulosis woringer kolopp disease
    Journal Der Deutschen Dermatologischen Gesellschaft, 2009
    Co-Authors: V. Lichte, Annette Geyer, Mathias Mohrle, Kamran Ghoreschi, Gisela Metzler, Martin Röcken, Martin Schaller
    Abstract:

    Summary Pagetoid Reticulosis (Woringer-Kolopp disease) is a rare subtype of cutaneous CD8-positive T-cell lymphoma. A 41-year-old man presented with a 7-year history with a slowly progressive erythematous plaque on his right buttocks. With the working diagnosis of psoriasis, he was treated with topical corticosteroids which produced no improvement. Histological examination showed an epidermotropic T-cell lymphoma with predominance of CD8- vs.CD4-positive lymphocytes. Based on the clinical picture and the histological findings, we diagnosed pagetoid Reticulosis. Excision of the plaque and cream PUVA photo-chemotherapy produced long-term remission.

V. Lichte - One of the best experts on this subject based on the ideXlab platform.

  • pagetoid Reticulosis woringer kolopp disease
    Journal Der Deutschen Dermatologischen Gesellschaft, 2009
    Co-Authors: V. Lichte, Annette Geyer, Mathias Mohrle, Kamran Ghoreschi, Gisela Metzler, Martin Röcken, Martin Schaller
    Abstract:

    Summary Pagetoid Reticulosis (Woringer-Kolopp disease) is a rare subtype of cutaneous CD8-positive T-cell lymphoma. A 41-year-old man presented with a 7-year history with a slowly progressive erythematous plaque on his right buttocks. With the working diagnosis of psoriasis, he was treated with topical corticosteroids which produced no improvement. Histological examination showed an epidermotropic T-cell lymphoma with predominance of CD8- vs.CD4-positive lymphocytes. Based on the clinical picture and the histological findings, we diagnosed pagetoid Reticulosis. Excision of the plaque and cream PUVA photo-chemotherapy produced long-term remission.

  • pagetoid Reticulosis woringer kolopp disease
    Journal Der Deutschen Dermatologischen Gesellschaft, 2009
    Co-Authors: V. Lichte, Annette Geyer, Mathias Mohrle, Kamran Ghoreschi, Gisela Metzler, Martin Röcken, Martin Schaller
    Abstract:

    Summary Pagetoid Reticulosis (Woringer-Kolopp disease) is a rare subtype of cutaneous CD8-positive T-cell lymphoma. A 41-year-old man presented with a 7-year history with a slowly progressive erythematous plaque on his right buttocks. With the working diagnosis of psoriasis, he was treated with topical corticosteroids which produced no improvement. Histological examination showed an epidermotropic T-cell lymphoma with predominance of CD8- vs.CD4-positive lymphocytes. Based on the clinical picture and the histological findings, we diagnosed pagetoid Reticulosis. Excision of the plaque and cream PUVA photo-chemotherapy produced long-term remission.

Steven T. Pals - One of the best experts on this subject based on the ideXlab platform.

  • expression of adhesion molecules in pagetoid Reticulosis woringer kolopp disease
    British Journal of Dermatology, 1997
    Co-Authors: Paul Drillenburg, C.m. Bronkhorst, L A Noorduyn, R. Hoekzema, Steven T. Pals
    Abstract:

    : Cell adhesion molecules play a critical role in lymphocyte migration and homing. They convey tissue-specific homing properties to lymphocyte subsets and regulate the positioning of these subsets in the body. In a patient with pagetoid Reticulosis, a rare form of cutaneous T-cell lymphoma characterized by extreme epitheliotropism, we examined the expression of adhesion molecules. The neoplastic T lymphocytes showed a strong expression of cutaneous lymphocyte antigen, a skin-homing receptor which interacts with E-selectin on skin endothelium. alpha E beta 7 an adhesion molecule interacting with E-cadherin on epithelial cells, was also expressed on tumour cells. These findings suggest that adhesion molecules are responsible for the unique growth pattern in pagetoid Reticulosis, and for the clinical behaviour of the disorder.

  • expression of adhesion molecules in pagetoid Reticulosis woringer kolopp disease
    British Journal of Dermatology, 1997
    Co-Authors: Paul Drillenburg, C.m. Bronkhorst, L A Noorduyn, R. Hoekzema, A C Van Der Wal, Steven T. Pals
    Abstract:

    Summary Cell adhesion molecules play a critical role in lytnphocyte migration and homing. They convey tissue-specific homing properties to lymphocyte subsets and regulate the positioning of these subsets in the body. In a patient with pagetoid Reticulosis. a rare form of cutaneous T-cell lymphoma characterized by extreme epitheliotropism. we examined the expression of adhesion molecules. The neoplastic T lymphocytes showed a strong expression of cutaneous lymphocyte antigen, a skinhoming receptor which interacts with E-selectin on skin endothelium. αEβ7, an adhesion molecule interacting with E-cadherin on epithelial cells, was also expressed on tumour cells. These findings suggest that adhesion molecules are responsible for the unque growth pattern in pagetoid Reticulosis. and for the clinical behaviour of the disorder.

Masaru Tanaka - One of the best experts on this subject based on the ideXlab platform.

  • Dermoscopic Features of CD8-Positive Solitary Pagetoid Reticulosis on the Left Leg
    2013
    Co-Authors: Reiko Suzaki, Mariko Fujibayashi, Sumiko Ishizaki, Ken Kobayashi, Masaru Tanaka
    Abstract:

    Copyright © 2010 Reiko Suzaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Solitary pagetoid Reticulosis, also known as Woringer-Kolopp disease, is a rare subtype of cutaneous T-cell lymphoma. The typical clinical presentation is a solitary, localized psoriasiform or hyperkeratotic plaque or tumor located on the extremities. It primarily affects middle-aged males. Because the clinical features of pagetoid Reticulosis are indistinctive, pagetoid Reticulosis may progress for years before accurate diagnosis. We reported a 57-year-old Japanese woman who presented with a 1-year history of a solitary erythematous plaque on the left leg. Dermoscopic features simulated Bowen’s disease showing dotted and glomerular vessels, whitish scaly areas, and a broad negative network. Dermoscopic features of pagetoid Reticulosis have never been reported. We have discussed the diagnostic significance of the observed dermoscopic findings. 1. Case Report A 57-year-old Japanese woman presented with a 1-year history of a solitary erythematous plaque on the left leg (Figures 1(a) and 1(b)). She had been treated with topical corticosteroid for a year without any improvement. The physical examination revealed a solitary erythematous plaqu

  • dermoscopic features of cd8 positive solitary pagetoid Reticulosis on the left leg
    Dermatology Research and Practice, 2010
    Co-Authors: Reiko Suzaki, Mariko Fujibayashi, Sumiko Ishizaki, Ken Kobayashi, Masaru Tanaka
    Abstract:

    Solitary pagetoid Reticulosis, also known as Woringer-Kolopp disease, is a rare subtype of cutaneous T-cell lymphoma. The typical clinical presentation is a solitary, localized psoriasiform or hyperkeratotic plaque or tumor located on the extremities. It primarily affects middle-aged males. Because the clinical features of pagetoid Reticulosis are indistinctive, pagetoid Reticulosis may progress for years before accurate diagnosis. We reported a 57-year-old Japanese woman who presented with a 1-year history of a solitary erythematous plaque on the left leg. Dermoscopic features simulated Bowen's disease showing dotted and glomerular vessels, whitish scaly areas, and a broad negative network. Dermoscopic features of pagetoid Reticulosis have never been reported. We have discussed the diagnostic significance of the observed dermoscopic findings.

Sabine Kohler - One of the best experts on this subject based on the ideXlab platform.

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