The Experts below are selected from a list of 36 Experts worldwide ranked by ideXlab platform
Alfred Christian Feller - One of the best experts on this subject based on the ideXlab platform.
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Sarcoma of follicular dendritic Cells with features of sinus lining Cells—a new subtype of Reticulum Cell sarcoma?
Virchows Archiv, 2008Co-Authors: M Krokowski, Hartmut Merz, Christoph Thorns, Heinz-wolfram Bernd, Ulrika Schade, Agnes Tourneau, Jacques Diebold, Alfred Christian FellerAbstract:Dendritic Cell neoplasms of the World Health Organization classification comprise Langerhans Cell histiocytosis, Langerhans Cell sarcoma, interdigitating dendritic Cell sarcoma, follicular dendritic Cell sarcoma, and dendritic Cell sarcoma, not otherwise specified. Several studies based on immunohistochemical and ultrastructural analysis tried to further clarify the origin of these neoplasms which are thought to derive from mesenchymal or bone marrow precursors. Lymphatic vessel endothelium hyaluronan receptor-1 (LYVE-1) was recently described as a marker for lymphatic endothelium which is expressed on normal liver blood sinusoid lining Cells, spleen endothelium, activated tissue macrophages, blood vessels in the lung, endothelial Cells of lymphatic sinuses, and in fibroblastic reticular Cells in lymph nodes. We present a case of LYVE-1-positive Reticulum Cell neoplasm in an axillary lymph node. To the best of our knowledge, there has been no report about LYVE-1 expression in histiocytic or dendritic Cell neoplasms so far. Due to the assumed specificity of this antibody, we propose designation of this Reticulum Cell sarcoma as lymphatic sinus lining Cell sarcoma which might finally represent another subtype of Reticulum Cell sarcomas.
Ifrah N - One of the best experts on this subject based on the ideXlab platform.
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A LYMPH NODE INTERDIGITATING Reticulum Cell SARCOMA
Archives of pathology & laboratory medicine, 1994Co-Authors: S. Francois, A. Croue, Maigre M, J. P. Saint-andre, Ifrah NAbstract:A 20-year-old woman presented with bilateral cervical, supraclavicular, and mediastinal lymphadenopathy. A nodal biopsy specimen showed a diffuse malignant proliferation of large pleomorphic Cells. The ultrastructural features and the antigen phenotype (expression of HLA-DR, CD68, alpha 1-antichymotrypsin, and S100 protein and inconstant reactivity for CD11c, CD15, and peanut agglutinin) were consistent with a derivation from interdigitating Reticulum Cells. Despite intensive combination chemotherapy with autologous bone marrow transplantation and local irradiation, the patient relapsed in the initial sites of the disease. A review of 12 previous reports of interdigitating Reticulum Cell sarcomas showed that most of these rare tumors behaved aggressively and were unresponsive to classic intensive chemotherapeutic regimens.
M Krokowski - One of the best experts on this subject based on the ideXlab platform.
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Sarcoma of follicular dendritic Cells with features of sinus lining Cells—a new subtype of Reticulum Cell sarcoma?
Virchows Archiv, 2008Co-Authors: M Krokowski, Hartmut Merz, Christoph Thorns, Heinz-wolfram Bernd, Ulrika Schade, Agnes Tourneau, Jacques Diebold, Alfred Christian FellerAbstract:Dendritic Cell neoplasms of the World Health Organization classification comprise Langerhans Cell histiocytosis, Langerhans Cell sarcoma, interdigitating dendritic Cell sarcoma, follicular dendritic Cell sarcoma, and dendritic Cell sarcoma, not otherwise specified. Several studies based on immunohistochemical and ultrastructural analysis tried to further clarify the origin of these neoplasms which are thought to derive from mesenchymal or bone marrow precursors. Lymphatic vessel endothelium hyaluronan receptor-1 (LYVE-1) was recently described as a marker for lymphatic endothelium which is expressed on normal liver blood sinusoid lining Cells, spleen endothelium, activated tissue macrophages, blood vessels in the lung, endothelial Cells of lymphatic sinuses, and in fibroblastic reticular Cells in lymph nodes. We present a case of LYVE-1-positive Reticulum Cell neoplasm in an axillary lymph node. To the best of our knowledge, there has been no report about LYVE-1 expression in histiocytic or dendritic Cell neoplasms so far. Due to the assumed specificity of this antibody, we propose designation of this Reticulum Cell sarcoma as lymphatic sinus lining Cell sarcoma which might finally represent another subtype of Reticulum Cell sarcomas.
Hartmut Merz - One of the best experts on this subject based on the ideXlab platform.
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Sarcoma of follicular dendritic Cells with features of sinus lining Cells—a new subtype of Reticulum Cell sarcoma?
Virchows Archiv, 2008Co-Authors: M Krokowski, Hartmut Merz, Christoph Thorns, Heinz-wolfram Bernd, Ulrika Schade, Agnes Tourneau, Jacques Diebold, Alfred Christian FellerAbstract:Dendritic Cell neoplasms of the World Health Organization classification comprise Langerhans Cell histiocytosis, Langerhans Cell sarcoma, interdigitating dendritic Cell sarcoma, follicular dendritic Cell sarcoma, and dendritic Cell sarcoma, not otherwise specified. Several studies based on immunohistochemical and ultrastructural analysis tried to further clarify the origin of these neoplasms which are thought to derive from mesenchymal or bone marrow precursors. Lymphatic vessel endothelium hyaluronan receptor-1 (LYVE-1) was recently described as a marker for lymphatic endothelium which is expressed on normal liver blood sinusoid lining Cells, spleen endothelium, activated tissue macrophages, blood vessels in the lung, endothelial Cells of lymphatic sinuses, and in fibroblastic reticular Cells in lymph nodes. We present a case of LYVE-1-positive Reticulum Cell neoplasm in an axillary lymph node. To the best of our knowledge, there has been no report about LYVE-1 expression in histiocytic or dendritic Cell neoplasms so far. Due to the assumed specificity of this antibody, we propose designation of this Reticulum Cell sarcoma as lymphatic sinus lining Cell sarcoma which might finally represent another subtype of Reticulum Cell sarcomas.
Christoph Thorns - One of the best experts on this subject based on the ideXlab platform.
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Sarcoma of follicular dendritic Cells with features of sinus lining Cells—a new subtype of Reticulum Cell sarcoma?
Virchows Archiv, 2008Co-Authors: M Krokowski, Hartmut Merz, Christoph Thorns, Heinz-wolfram Bernd, Ulrika Schade, Agnes Tourneau, Jacques Diebold, Alfred Christian FellerAbstract:Dendritic Cell neoplasms of the World Health Organization classification comprise Langerhans Cell histiocytosis, Langerhans Cell sarcoma, interdigitating dendritic Cell sarcoma, follicular dendritic Cell sarcoma, and dendritic Cell sarcoma, not otherwise specified. Several studies based on immunohistochemical and ultrastructural analysis tried to further clarify the origin of these neoplasms which are thought to derive from mesenchymal or bone marrow precursors. Lymphatic vessel endothelium hyaluronan receptor-1 (LYVE-1) was recently described as a marker for lymphatic endothelium which is expressed on normal liver blood sinusoid lining Cells, spleen endothelium, activated tissue macrophages, blood vessels in the lung, endothelial Cells of lymphatic sinuses, and in fibroblastic reticular Cells in lymph nodes. We present a case of LYVE-1-positive Reticulum Cell neoplasm in an axillary lymph node. To the best of our knowledge, there has been no report about LYVE-1 expression in histiocytic or dendritic Cell neoplasms so far. Due to the assumed specificity of this antibody, we propose designation of this Reticulum Cell sarcoma as lymphatic sinus lining Cell sarcoma which might finally represent another subtype of Reticulum Cell sarcomas.