The Experts below are selected from a list of 138 Experts worldwide ranked by ideXlab platform

Bittman - One of the best experts on this subject based on the ideXlab platform.

  • Co-Expression of Melatonin (MEL1a) Receptor and Arginine Vasopressin mRNAs in the Siberian Hamster Suprachiasmatic Nucleus
    Journal of Neuroendocrinology, 2001
    Co-Authors: C. Kay Song, Bartness, Petersen, Bittman
    Abstract:

    Durational melatonin signals, cued by the photoperiod and generated by the pineal gland, are processed in the brain to induce seasonally appropriate physiological and behavioural adaptations. The melatonin receptor subtype MEL1a (also known as mt1) appears to regulate seasonal responses. Single label in situ hybridization for MEL1a receptor mRNA revealed labelled cells in several brain regions of Siberian hamsters, including the suprachiasmatic Nucleus, the paraventricular Nucleus of the thalamus, and the Reuniens Nucleus of the thalamus. To characterize suprachiasmatic Nucleus cells containing MEL1a receptor mRNA, we used 35S-labelled cRNA probes for MEL1a receptor mRNA in combination with digoxigenin-labelled cRNA probes for vasopressin, somatostatin, or orphan retinoid Z receptor β (RZRβ; a putative nuclear melatonin receptor). Cells in the suprachiasmatic Nucleus that contained MEL1a receptor mRNA also contained mRNAs for vasopressin and RZRβ, but not for somatostatin. These data suggest that suprachiasmatic Nucleus vasopressin cells may respond to melatonin signals, raising the possibility that suprachiasmatic Nucleus vasopressin output mediates some of the effects of melatonin on seasonal or circadian responses.

  • Co-Expression of Melatonin (MEL1a) Receptor and Arginine Vasopressin mRNAs in the Siberian Hamster Suprachiasmatic Nucleus
    Journal of Neuroendocrinology, 2001
    Co-Authors: C. Kay Song, Bartness, Petersen, Bittman
    Abstract:

    Durational melatonin signals, cued by the photoperiod and generated by the pineal gland, are processed in the brain to induce seasonally appropriate physiological and behavioural adaptations. The melatonin receptor subtype MEL1a (also known as mt1) appears to regulate seasonal responses. Single label in situ hybridization for MEL1a receptor mRNA revealed labelled cells in several brain regions of Siberian hamsters, including the suprachiasmatic Nucleus, the paraventricular Nucleus of the thalamus, and the Reuniens Nucleus of the thalamus. To characterize suprachiasmatic Nucleus cells containing MEL1a receptor mRNA, we used 35S-labelled cRNA probes for MEL1a receptor mRNA in combination with digoxigenin-labelled cRNA probes for vasopressin, somatostatin, or orphan retinoid Z receptor β (RZRβ; a putative nuclear melatonin receptor). Cells in the suprachiasmatic Nucleus that contained MEL1a receptor mRNA also contained mRNAs for vasopressin and RZRβ, but not for somatostatin. These data suggest that suprachiasmatic Nucleus vasopressin cells may respond to melatonin signals, raising the possibility that suprachiasmatic Nucleus vasopressin output mediates some of the effects of melatonin on seasonal or circadian responses.

Lyndell Eleore - One of the best experts on this subject based on the ideXlab platform.

  • Learning curves and evolution of synaptic field potentials evoked in the PFC by electrical stimulation of the Reuniens Nucleus for controls (A, B) and following two HFS sessions (C, D).
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) Evolution of fEPSPs evoked at the Reuniens-PFC synapse across the successive habituation, conditioning, and extinction sessions. At the top are illustrated selected fEPSPs recorded in the PFC during the indicated sessions, following a single pulse presented to the Reuniens Nucleus. Note that no significant change in fEPSP amplitude was observed across conditioning. Calibrations as indicated. (B) Evolution of the percentage (%) of conditioned responses during the successive sessions. Mean % values are followed by ± s.e.m. (C) Evolution of fEPSPs evoked at the Reuniens-PFC synapse across training, following two HFS sessions presented 30 min before the first two conditioning sessions. Note that these HFS sessions did not evoke any noticeable LTP in fEPSPs recorded in the PFC. (D) Evolution of the percentage (%) of conditioned responses during the successive sessions following the two HFS sessions. Note the small increase in the percentage of conditioned responses. *, P

  • Learning curves and evolution of synaptic field potentials evoked in the CA1 area by the electrical stimulation of the Reuniens Nucleus for controls (A, B) and following two HFS sessions (C, D).
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) Evolution of fEPSPs evoked at the Reuniens-CA1 synapse across the successive habituation, conditioning, and extinction sessions. At the top are illustrated selected fEPSPs recorded in the CA1 area during the indicated sessions, following a single pulse presented to the Reuniens Nucleus. Note that no significant change in fEPSP amplitude was observed across conditioning. Calibrations as indicated. (B) Evolution of the percentage (%) of conditioned responses during the successive sessions. Mean % values are followed by ± s.e.m. (C) Evolution of fEPSPs evoked at the Reuniens-CA1 synapse across training, following two HFS sessions presented 30 min before the first two conditioning sessions. Note that these HFS sessions did not evoke any noticeable LTP in fEPSPs recorded in the CA1 area. (D) Evolution of the percentage (%) of conditioned responses during the successive sessions following the two HFS sessions. Note the small increase in the percentage of conditioned responses. *, P

  • Experimental design.
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) EMG recording electrodes were implanted in the orbicularis oculi (O.O.) muscle of the upper left eyelid. In addition, bipolar stimulating electrodes were implanted on the ipsilateral supraorbital nerve for presentation of unconditioned stimulus (US). The conditioned stimulus (CS) consisted of a tone delivered from a loudspeaker located 30 cm from the animal's head. Animals were also implanted with stimulating electrodes in the thalamic Reuniens Nucleus and with recording electrodes in the medial prefrontal cortex (top diagram) or the hippocampal CA1 area (bottom diagram). (B–D) Photomicrographs illustrating the location of recording electrodes in the mPFC (B) and in the hippocampal CA1 area (D), as well as the stimulation (C) site (arrows). Calibration bars 500 µm. Abbreviations: D, L, M, V, dorsal, lateral, medial, and ventral. E, A schematic representation of the conditioning paradigm, illustrating CS and US stimuli, and the moment at which a single pulse (100 µs, square, biphasic) was presented to the Reuniens Nucleus (St. Reu.). An example of an EMG record from the orbicularis oculi (O.O.) muscle obtained from the 9th conditioning session is illustrated, as well as an extracellular record of hippocampal activity from the same animal, session, and trial. Note the fEPSPs evoked by the pulse presented to the Reuniens Nucleus.

  • Input/output curves and paired-pulse stimulation of the Reuniens-mPFC and Reuniens-CA1 synapses using paired-pulse stimulation.
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) Relationships between the intensity (in mA) of pairs of stimuli (40 ms of interstimulus interval) presented to the Reuniens Nucleus and the amplitude of the fEPSPs evoked in the mPFC by the 1st (black triangles) and the 2nd (white triangles) pulses. Data are represented as mean ± s.e.m. *, P

  • Effects of two HFS sessions on the Reuniens-CA1 and Reuniens-mPFC synapses.
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A, B) Evolution of fEPSPs evoked in the PFC (A) and in the CA1 area (B) by paired-pulse stimulation of Reuniens Nucleus before and after two HFS sessions. Each animal was presented with two HFS sessions (see shaded areas) each consisting of five 200 Hz, 100 ms trains of pulses at a rate of 1/s. This protocol was presented six times, at intervals of 1 min. The 100 µs, square, biphasic pulses used to evoke LTP were applied at the same intensity used for the single pulse presented following HFS presentation. The evolution of LTP was checked using a pair of pulses (1st, black circles; 2nd, white circles) with an interstimulus interval of 40 ms. Recording was carried out for 72 h. Note that fEPSP amplitudes evoked by the 1st and the 2nd pulses reached values below baseline following the two HFS sessions for both synapses. *, P

C. Kay Song - One of the best experts on this subject based on the ideXlab platform.

  • Co-Expression of Melatonin (MEL1a) Receptor and Arginine Vasopressin mRNAs in the Siberian Hamster Suprachiasmatic Nucleus
    Journal of Neuroendocrinology, 2001
    Co-Authors: C. Kay Song, Bartness, Petersen, Bittman
    Abstract:

    Durational melatonin signals, cued by the photoperiod and generated by the pineal gland, are processed in the brain to induce seasonally appropriate physiological and behavioural adaptations. The melatonin receptor subtype MEL1a (also known as mt1) appears to regulate seasonal responses. Single label in situ hybridization for MEL1a receptor mRNA revealed labelled cells in several brain regions of Siberian hamsters, including the suprachiasmatic Nucleus, the paraventricular Nucleus of the thalamus, and the Reuniens Nucleus of the thalamus. To characterize suprachiasmatic Nucleus cells containing MEL1a receptor mRNA, we used 35S-labelled cRNA probes for MEL1a receptor mRNA in combination with digoxigenin-labelled cRNA probes for vasopressin, somatostatin, or orphan retinoid Z receptor β (RZRβ; a putative nuclear melatonin receptor). Cells in the suprachiasmatic Nucleus that contained MEL1a receptor mRNA also contained mRNAs for vasopressin and RZRβ, but not for somatostatin. These data suggest that suprachiasmatic Nucleus vasopressin cells may respond to melatonin signals, raising the possibility that suprachiasmatic Nucleus vasopressin output mediates some of the effects of melatonin on seasonal or circadian responses.

  • Co-Expression of Melatonin (MEL1a) Receptor and Arginine Vasopressin mRNAs in the Siberian Hamster Suprachiasmatic Nucleus
    Journal of Neuroendocrinology, 2001
    Co-Authors: C. Kay Song, Bartness, Petersen, Bittman
    Abstract:

    Durational melatonin signals, cued by the photoperiod and generated by the pineal gland, are processed in the brain to induce seasonally appropriate physiological and behavioural adaptations. The melatonin receptor subtype MEL1a (also known as mt1) appears to regulate seasonal responses. Single label in situ hybridization for MEL1a receptor mRNA revealed labelled cells in several brain regions of Siberian hamsters, including the suprachiasmatic Nucleus, the paraventricular Nucleus of the thalamus, and the Reuniens Nucleus of the thalamus. To characterize suprachiasmatic Nucleus cells containing MEL1a receptor mRNA, we used 35S-labelled cRNA probes for MEL1a receptor mRNA in combination with digoxigenin-labelled cRNA probes for vasopressin, somatostatin, or orphan retinoid Z receptor β (RZRβ; a putative nuclear melatonin receptor). Cells in the suprachiasmatic Nucleus that contained MEL1a receptor mRNA also contained mRNAs for vasopressin and RZRβ, but not for somatostatin. These data suggest that suprachiasmatic Nucleus vasopressin cells may respond to melatonin signals, raising the possibility that suprachiasmatic Nucleus vasopressin output mediates some of the effects of melatonin on seasonal or circadian responses.

José M. Delgado-garcía - One of the best experts on this subject based on the ideXlab platform.

  • Learning curves and evolution of synaptic field potentials evoked in the PFC by electrical stimulation of the Reuniens Nucleus for controls (A, B) and following two HFS sessions (C, D).
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) Evolution of fEPSPs evoked at the Reuniens-PFC synapse across the successive habituation, conditioning, and extinction sessions. At the top are illustrated selected fEPSPs recorded in the PFC during the indicated sessions, following a single pulse presented to the Reuniens Nucleus. Note that no significant change in fEPSP amplitude was observed across conditioning. Calibrations as indicated. (B) Evolution of the percentage (%) of conditioned responses during the successive sessions. Mean % values are followed by ± s.e.m. (C) Evolution of fEPSPs evoked at the Reuniens-PFC synapse across training, following two HFS sessions presented 30 min before the first two conditioning sessions. Note that these HFS sessions did not evoke any noticeable LTP in fEPSPs recorded in the PFC. (D) Evolution of the percentage (%) of conditioned responses during the successive sessions following the two HFS sessions. Note the small increase in the percentage of conditioned responses. *, P

  • Learning curves and evolution of synaptic field potentials evoked in the CA1 area by the electrical stimulation of the Reuniens Nucleus for controls (A, B) and following two HFS sessions (C, D).
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) Evolution of fEPSPs evoked at the Reuniens-CA1 synapse across the successive habituation, conditioning, and extinction sessions. At the top are illustrated selected fEPSPs recorded in the CA1 area during the indicated sessions, following a single pulse presented to the Reuniens Nucleus. Note that no significant change in fEPSP amplitude was observed across conditioning. Calibrations as indicated. (B) Evolution of the percentage (%) of conditioned responses during the successive sessions. Mean % values are followed by ± s.e.m. (C) Evolution of fEPSPs evoked at the Reuniens-CA1 synapse across training, following two HFS sessions presented 30 min before the first two conditioning sessions. Note that these HFS sessions did not evoke any noticeable LTP in fEPSPs recorded in the CA1 area. (D) Evolution of the percentage (%) of conditioned responses during the successive sessions following the two HFS sessions. Note the small increase in the percentage of conditioned responses. *, P

  • Experimental design.
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) EMG recording electrodes were implanted in the orbicularis oculi (O.O.) muscle of the upper left eyelid. In addition, bipolar stimulating electrodes were implanted on the ipsilateral supraorbital nerve for presentation of unconditioned stimulus (US). The conditioned stimulus (CS) consisted of a tone delivered from a loudspeaker located 30 cm from the animal's head. Animals were also implanted with stimulating electrodes in the thalamic Reuniens Nucleus and with recording electrodes in the medial prefrontal cortex (top diagram) or the hippocampal CA1 area (bottom diagram). (B–D) Photomicrographs illustrating the location of recording electrodes in the mPFC (B) and in the hippocampal CA1 area (D), as well as the stimulation (C) site (arrows). Calibration bars 500 µm. Abbreviations: D, L, M, V, dorsal, lateral, medial, and ventral. E, A schematic representation of the conditioning paradigm, illustrating CS and US stimuli, and the moment at which a single pulse (100 µs, square, biphasic) was presented to the Reuniens Nucleus (St. Reu.). An example of an EMG record from the orbicularis oculi (O.O.) muscle obtained from the 9th conditioning session is illustrated, as well as an extracellular record of hippocampal activity from the same animal, session, and trial. Note the fEPSPs evoked by the pulse presented to the Reuniens Nucleus.

  • Input/output curves and paired-pulse stimulation of the Reuniens-mPFC and Reuniens-CA1 synapses using paired-pulse stimulation.
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A) Relationships between the intensity (in mA) of pairs of stimuli (40 ms of interstimulus interval) presented to the Reuniens Nucleus and the amplitude of the fEPSPs evoked in the mPFC by the 1st (black triangles) and the 2nd (white triangles) pulses. Data are represented as mean ± s.e.m. *, P

  • Effects of two HFS sessions on the Reuniens-CA1 and Reuniens-mPFC synapses.
    2013
    Co-Authors: Lyndell Eleore, Juan Carlos López-ramos, Rafael Guerra-narbona, José M. Delgado-garcía
    Abstract:

    (A, B) Evolution of fEPSPs evoked in the PFC (A) and in the CA1 area (B) by paired-pulse stimulation of Reuniens Nucleus before and after two HFS sessions. Each animal was presented with two HFS sessions (see shaded areas) each consisting of five 200 Hz, 100 ms trains of pulses at a rate of 1/s. This protocol was presented six times, at intervals of 1 min. The 100 µs, square, biphasic pulses used to evoke LTP were applied at the same intensity used for the single pulse presented following HFS presentation. The evolution of LTP was checked using a pair of pulses (1st, black circles; 2nd, white circles) with an interstimulus interval of 40 ms. Recording was carried out for 72 h. Note that fEPSP amplitudes evoked by the 1st and the 2nd pulses reached values below baseline following the two HFS sessions for both synapses. *, P

Kay C Song - One of the best experts on this subject based on the ideXlab platform.

  • co expression of melatonin mel1a receptor and arginine vasopressin mrnas in the siberian hamster suprachiasmatic Nucleus
    Journal of Neuroendocrinology, 2001
    Co-Authors: Kay C Song
    Abstract:

    : Durational melatonin signals, cued by the photoperiod and generated by the pineal gland, are processed in the brain to induce seasonally appropriate physiological and behavioural adaptations. The melatonin receptor subtype MEL1a (also known as mt1) appears to regulate seasonal responses. Single label in situ hybridization for MEL1a receptor mRNA revealed labelled cells in several brain regions of Siberian hamsters, including the suprachiasmatic Nucleus, the paraventricular Nucleus of the thalamus, and the Reuniens Nucleus of the thalamus. To characterize suprachiasmatic Nucleus cells containing MEL1a receptor mRNA, we used 35S-labelled cRNA probes for MEL1a receptor mRNA in combination with digoxigenin-labelled cRNA probes for vasopressin, somatostatin, or orphan retinoid Z receptor beta (RZRbeta; a putative nuclear melatonin receptor). Cells in the suprachiasmatic Nucleus that contained MEL1a receptor mRNA also contained mRNAs for vasopressin and RZRbeta, but not for somatostatin. These data suggest that suprachiasmatic Nucleus vasopressin cells may respond to melatonin signals, raising the possibility that suprachiasmatic Nucleus vasopressin output mediates some of the effects of melatonin on seasonal or circadian responses.