The Experts below are selected from a list of 1260 Experts worldwide ranked by ideXlab platform
Hayder M Al-kuraishy - One of the best experts on this subject based on the ideXlab platform.
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Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy
SAGEYA, 2016Co-Authors: Hayder M Al-kuraishyAbstract:Abstract Aim: The present study investigates the effect of combined treatment with Ginkgo biloba and/or Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy. Subjects and Methods: A total number of 112 volunteers was enrolled to study the effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy as compared to placebo effects,the central cognitive effect was assessed by Critical flicker-fusion frequency (CFFF), Psychomotor vigilance Task (PVT) and computerized N-back test. Results: Placebo produced no significant effects on all neurocognitive tests measure p>0.05 in normal healthy volunteers, Ginkgo biloba or Rhodiola rosea improve psychomotor vigilance task and low to moderate working memory accuracy, The combined effect of Rhodiola rosea and Ginkgo biloba leading to more significant effect on psychomotor vigilance task, all levels of short term working memory accuracy and critical fusion versus flicker p [J Complement Med Res 2016; 5(1.000): 7-13
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Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy
Journal of intercultural ethnopharmacology, 2015Co-Authors: Hayder M Al-kuraishyAbstract:Abstract Aim: The present study investigates the effect of combined treatment with Ginkgo biloba and/or Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy. Subjects and Methods: A total number of 112 volunteers was enrolled to study the effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy as compared to placebo effects,the central cognitive effect was assessed by Critical flicker-fusion frequency (CFFF), Psychomotor vigilance Task (PVT) and computerized N-back test. Results: Placebo produced no significant effects on all neurocognitive tests measure p>0.05 in normal healthy volunteers, Ginkgo biloba or Rhodiola rosea improve psychomotor vigilance task and low to moderate working memory accuracy, The combined effect of Rhodiola rosea and Ginkgo biloba leading to more significant effect on psychomotor vigilance task, all levels of short term working memory accuracy and critical fusion versus flicker p
Jerome Sarris - One of the best experts on this subject based on the ideXlab platform.
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rosenroot Rhodiola rosea traditional use chemical composition pharmacology and clinical efficacy
Phytomedicine, 2010Co-Authors: Alexander Panossian, G Wikman, Jerome SarrisAbstract:The aim of this review article was to summarize accumulated information related to chemical composition, pharmacological activity, traditional and official use of Rhodiola rosea L. in medicine. In total approximately 140 compounds were isolated from roots and rhizome - monoterpene alcohols and their glycosides, cyanogenic glycosides, aryl glycosides, phenylethanoids, phenylpropanoids and their glycosides, flavonoids, flavonlignans, proanthocyanidins and gallic acid derivatives. Studies on isolated organs, tissues, cells and enzymes have revealed that Rhodiola preparations exhibit adaptogenic effect including, neuroprotective, cardioprotectiv e, anti-fatigue, antidepressive, anxiolytic, nootropic, life-span increasing effects and CNS stimulating activity. A number of clinical trials demonstrate that repeated administration of R. rosea extract SHR-5 exerts an anti-fatigue effect that increases mental performance (particularly the ability to concentrate in healthy subjects), and reduces burnout in patients with fatigue syndrome. Encouraging results exist for the use of Rhodiola in mild to moderate depression, and generalized anxiety. Several mechanisms of action possibly contributing to the clinical effect have been identified for Rhodiola extracts. They include interactions with HPA-system (cortisol-reducing), protein kinases p-JNK, nitric oxide, and defense mechanism proteins (e.g. heat shock proteins Hsp 70 and FoxO/DAF-16). Lack of interaction with other drugs and adverse effects in the course of clinical trials make it potentially attractive for use as a safe medication. In conclusion, Rhodiola rosea has robust traditional and pharmacological evidence of use in fatigue, and emerging evidence supporting cognition and mood.
Rebecca R Rogers - One of the best experts on this subject based on the ideXlab platform.
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Effects of Short-Term Golden Root Extract (Rhodiola rosea) Supplementation on Resistance Exercise Performance
'MDPI AG', 2021Co-Authors: Tyler D. Williams, Rebecca R Rogers, Haley N. Langley, Caleb C. Roberson, Christopher G BallmannAbstract:The purpose of this study was to examine the effects of short-term Golden Root Extract (GRE; Rhodiola rosea) supplementation on blood lactate, catecholamines, and performance during repeated bench press exercise. Resistance-trained males (n = 10) participated in this study. In a double-blinded, crossover, counterbalanced study design, participants supplemented with either 1500 mg/day of GRE or placebo (PL; gluten-free cornstarch) for 3 days prior to experimentation. An additional 500 mg dose was ingested 30 min prior to exercise testing. During each exercise trial, participants completed 2 repetitions of bench press at 75% of one-repetition maximum (1RM) as explosively as possible. A linear position transducer was used to measure mean concentric velocity. After 5 min of rest, participants completed 3 sets × repetitions to failure (RTF) at 75% 1RM separated by 2 min of rest between each set. A capillary blood sample was obtained pre- (PRE) and immediately post- (POST) exercise to measure blood concentrations lactate (LA), epinephrine (EPI), and norepinephrine (NE). Mean concentric velocity was significantly higher with GRE when compared to PL (p = 0.046). However, total RTF were significantly lower with GRE versus PL (p p p = 0.049). EPI and NE increased in both conditions Pre to Post (p p = 0.008). Findings indicate that short-term GRE supplementation increases mean bench press velocity but decreases bench press repetition volume. Furthermore, GRE resulted in higher NE levels and blood lactate following exercise. Thus, supplementing with GRE may enhance explosive resistance training performance but may also impair upper body strength-endurance
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effects of short term Rhodiola rosea golden root extract supplementation on anaerobic exercise performance
Journal of Sports Sciences, 2019Co-Authors: Christopher G Ballmann, Shelby Maze, Abby Wells, Mallory R Marshall, Rebecca R RogersAbstract:The purpose of this study was to examine the effects of short-term Rhodiola rosea (Golden Root Extract (GRE)) supplementation on repeated Wingate performance. Eleven physically active college aged ...
Larissa Shamseer - One of the best experts on this subject based on the ideXlab platform.
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Rhodiola rosea for Mental and Physical Fatigue in Nursing Students: A Randomized Controlled Trial
2016Co-Authors: Salima Punja, Larissa Shamseer, Karin Olson, Sunita VohraAbstract:Background: Fatigue is one of many unintended consequences of shift work in the nursing profession. Natural health products (NHPs) for fatigue are becoming an increasingly popular topic of clinical study; one such NHP is Rhodiola rosea. A well-designed, rigorously conducted randomized controlled trial is required before therapeutic claims for this product can be made. Objective: To compare the efficacy of R. rosea with placebo for reducing fatigue in nursing students on shift work. Design: A parallel-group randomized, double-blinded, placebo-controlled trial of 18–55 year old students from the Faculty of Nursing from the University of Alberta, participating in clinical rotations between January 2011 and September 2011. Interventions: Participants were randomized to take 364 mg of either R. rosea or identical placebo at the start of their wakeful period and up to one additional capsule within the following four hours on a daily basis over a 42-day period. Outcomes: The primary outcome was reduction in fatigue over the 42-day trial period measured using the Vitality-subscale of the RAND-36, cross-validated by the visual analogue scale for fatigue (VAS-F). Secondary outcomes included health-related quality of life, individualized outcomes assessment, and adverse events. Results: A total of 48 participants were randomized to R. rosea (n = 24) or placebo (n = 24). The mean change in scores on the Vitality-subscale was significantly different between the study groups at day 42 in favor of placebo (217.3 (95 % CI
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Rhodiola rosea for physical and mental fatigue a systematic review
BMC Complementary and Alternative Medicine, 2012Co-Authors: Sana Ishaque, Larissa Shamseer, Cecilia Bukutu, Sunita VohraAbstract:Rhodiola rosea (R. rosea) is grown at high altitudes and northern latitudes. Due to its purported adaptogenic properties, it has been studied for its performance-enhancing capabilities in healthy populations and its therapeutic properties in a number of clinical populations. To systematically review evidence of efficacy and safety of R. rosea for physical and mental fatigue. Six electronic databases were searched to identify randomized controlled trials (RCTs) and controlled clinical trials (CCTs), evaluating efficacy and safety of R. rosea for physical and mental fatigue. Two reviewers independently screened the identified literature, extracted data and assessed risk of bias for included studies. Of 206 articles identified in the search, 11 met inclusion criteria for this review. Ten were described as RCTs and one as a CCT. Two of six trials examining physical fatigue in healthy populations report R. rosea to be effective as did three of five RCTs evaluating R. rosea for mental fatigue. All of the included studies exhibit either a high risk of bias or have reporting flaws that hinder assessment of their true validity (unclear risk of bias). Research regarding R. rosea efficacy is contradictory. While some evidence suggests that the herb may be helpful for enhancing physical performance and alleviating mental fatigue, methodological flaws limit accurate assessment of efficacy. A rigorously-designed well reported RCT that minimizes bias is needed to determine true efficacy of R. rosea for fatigue.
Sunita Vohra - One of the best experts on this subject based on the ideXlab platform.
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Rhodiola rosea for Mental and Physical Fatigue in Nursing Students: A Randomized Controlled Trial
2016Co-Authors: Salima Punja, Larissa Shamseer, Karin Olson, Sunita VohraAbstract:Background: Fatigue is one of many unintended consequences of shift work in the nursing profession. Natural health products (NHPs) for fatigue are becoming an increasingly popular topic of clinical study; one such NHP is Rhodiola rosea. A well-designed, rigorously conducted randomized controlled trial is required before therapeutic claims for this product can be made. Objective: To compare the efficacy of R. rosea with placebo for reducing fatigue in nursing students on shift work. Design: A parallel-group randomized, double-blinded, placebo-controlled trial of 18–55 year old students from the Faculty of Nursing from the University of Alberta, participating in clinical rotations between January 2011 and September 2011. Interventions: Participants were randomized to take 364 mg of either R. rosea or identical placebo at the start of their wakeful period and up to one additional capsule within the following four hours on a daily basis over a 42-day period. Outcomes: The primary outcome was reduction in fatigue over the 42-day trial period measured using the Vitality-subscale of the RAND-36, cross-validated by the visual analogue scale for fatigue (VAS-F). Secondary outcomes included health-related quality of life, individualized outcomes assessment, and adverse events. Results: A total of 48 participants were randomized to R. rosea (n = 24) or placebo (n = 24). The mean change in scores on the Vitality-subscale was significantly different between the study groups at day 42 in favor of placebo (217.3 (95 % CI
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Rhodiola rosea for physical and mental fatigue a systematic review
BMC Complementary and Alternative Medicine, 2012Co-Authors: Sana Ishaque, Larissa Shamseer, Cecilia Bukutu, Sunita VohraAbstract:Rhodiola rosea (R. rosea) is grown at high altitudes and northern latitudes. Due to its purported adaptogenic properties, it has been studied for its performance-enhancing capabilities in healthy populations and its therapeutic properties in a number of clinical populations. To systematically review evidence of efficacy and safety of R. rosea for physical and mental fatigue. Six electronic databases were searched to identify randomized controlled trials (RCTs) and controlled clinical trials (CCTs), evaluating efficacy and safety of R. rosea for physical and mental fatigue. Two reviewers independently screened the identified literature, extracted data and assessed risk of bias for included studies. Of 206 articles identified in the search, 11 met inclusion criteria for this review. Ten were described as RCTs and one as a CCT. Two of six trials examining physical fatigue in healthy populations report R. rosea to be effective as did three of five RCTs evaluating R. rosea for mental fatigue. All of the included studies exhibit either a high risk of bias or have reporting flaws that hinder assessment of their true validity (unclear risk of bias). Research regarding R. rosea efficacy is contradictory. While some evidence suggests that the herb may be helpful for enhancing physical performance and alleviating mental fatigue, methodological flaws limit accurate assessment of efficacy. A rigorously-designed well reported RCT that minimizes bias is needed to determine true efficacy of R. rosea for fatigue.