The Experts below are selected from a list of 1560 Experts worldwide ranked by ideXlab platform
Jag Bhawan - One of the best experts on this subject based on the ideXlab platform.
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cutaneous sinus histiocytosis rosai dorfman Disease presenting clinically as vasculitis
Journal of The American Academy of Dermatology, 2002Co-Authors: Catherine M Stefanato, Philip S Ellerin, Jag BhawanAbstract:Abstract The cutaneous variant of Rosai-Dorfman Disease is a rare benign lymphoproliferative disorder that occurs without lymphadenopathy or internal organ involvement. We present a 55-year-old woman with a diffuse exanthematous eruption that evolved into pruritic papulopetechial and purpuric lesions on the back and lower extremities, diagnosed clinically as a vasculitis. The patient's lesions cleared spontaneously with no recurrence. Histopathologic examination showed a dense dermal nodular lymphohistiocytic infiltrate with occasional eosinophils, plasma cells, and neutrophils and with numerous extravasated red blood cells. The large, foamy histiocytes exhibited abundant pale cytoplasm, feathery cytoplasmic borders, and emperipolesis. A few histiocytes had longitudinal nuclear grooves resembling Langerhans cells; however, these cells were positive for S-100 protein and negative for CD1a. The clinical presentation of the cutaneous variant of Rosai-Dorfman Disease is generally nonspecific. We present this case because of the unusual clinical presentation mimicking a vasculitis. (J Am Acad Dermatol 2002;46:775-8.)
Bernd W Scheithauer - One of the best experts on this subject based on the ideXlab platform.
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Isolated Intracranial Rosai-Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy)
2015Co-Authors: Eiichi Konishi, Norihiro Ibayashi, Shinji Yamamoto, Bernd W ScheithauerAbstract:massive lymphadenopathy) rarely affects the intracranial region without involvement of other sites. We report the case of a 68-year-old woman with isolated Rosai-Dorfman Disease of the frontal dura. She presented with a new onset seizure. Initial MR imaging showed subtle mild change in the left frontal region. During the ensuing 8 months, a dural mass made its symptomatic and definite MR imaging appearance in the same region. No extracranial lesion was present. Rosai-Dorfman Disease (sinus histiocytosis with massive lymphadenopathy) was first described in 1969 as a benign proliferative lesion with systemic symp-toms and lymphadenopathy (1). It occurs more often in children and young adults and shows a mild male sex predilection (2). Rosai-Dorfman Disease com
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isolated intracranial rosai dorfman Disease sinus histiocytosis with massive lymphadenopathy
American Journal of Neuroradiology, 2003Co-Authors: Eiichi Konishi, Norihiro Ibayashi, Shinji Yamamoto, Bernd W ScheithauerAbstract:Summary: Rosai-Dorfman Disease (sinus histiocytosis with massive lymphadenopathy) rarely affects the intracranial region without involvement of other sites. We report the case of a 68-year-old woman with isolated Rosai-Dorfman Disease of the frontal dura. She presented with a new onset seizure. Initial MR imaging showed subtle mild change in the left frontal region. During the ensuing 8 months, a dural mass made its symptomatic and definite MR imaging appearance in the same region. No extracranial lesion was present.
Catherine M Stefanato - One of the best experts on this subject based on the ideXlab platform.
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cutaneous sinus histiocytosis rosai dorfman Disease presenting clinically as vasculitis
Journal of The American Academy of Dermatology, 2002Co-Authors: Catherine M Stefanato, Philip S Ellerin, Jag BhawanAbstract:Abstract The cutaneous variant of Rosai-Dorfman Disease is a rare benign lymphoproliferative disorder that occurs without lymphadenopathy or internal organ involvement. We present a 55-year-old woman with a diffuse exanthematous eruption that evolved into pruritic papulopetechial and purpuric lesions on the back and lower extremities, diagnosed clinically as a vasculitis. The patient's lesions cleared spontaneously with no recurrence. Histopathologic examination showed a dense dermal nodular lymphohistiocytic infiltrate with occasional eosinophils, plasma cells, and neutrophils and with numerous extravasated red blood cells. The large, foamy histiocytes exhibited abundant pale cytoplasm, feathery cytoplasmic borders, and emperipolesis. A few histiocytes had longitudinal nuclear grooves resembling Langerhans cells; however, these cells were positive for S-100 protein and negative for CD1a. The clinical presentation of the cutaneous variant of Rosai-Dorfman Disease is generally nonspecific. We present this case because of the unusual clinical presentation mimicking a vasculitis. (J Am Acad Dermatol 2002;46:775-8.)
Eiichi Konishi - One of the best experts on this subject based on the ideXlab platform.
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Isolated Intracranial Rosai-Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy)
2015Co-Authors: Eiichi Konishi, Norihiro Ibayashi, Shinji Yamamoto, Bernd W ScheithauerAbstract:massive lymphadenopathy) rarely affects the intracranial region without involvement of other sites. We report the case of a 68-year-old woman with isolated Rosai-Dorfman Disease of the frontal dura. She presented with a new onset seizure. Initial MR imaging showed subtle mild change in the left frontal region. During the ensuing 8 months, a dural mass made its symptomatic and definite MR imaging appearance in the same region. No extracranial lesion was present. Rosai-Dorfman Disease (sinus histiocytosis with massive lymphadenopathy) was first described in 1969 as a benign proliferative lesion with systemic symp-toms and lymphadenopathy (1). It occurs more often in children and young adults and shows a mild male sex predilection (2). Rosai-Dorfman Disease com
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isolated intracranial rosai dorfman Disease sinus histiocytosis with massive lymphadenopathy
American Journal of Neuroradiology, 2003Co-Authors: Eiichi Konishi, Norihiro Ibayashi, Shinji Yamamoto, Bernd W ScheithauerAbstract:Summary: Rosai-Dorfman Disease (sinus histiocytosis with massive lymphadenopathy) rarely affects the intracranial region without involvement of other sites. We report the case of a 68-year-old woman with isolated Rosai-Dorfman Disease of the frontal dura. She presented with a new onset seizure. Initial MR imaging showed subtle mild change in the left frontal region. During the ensuing 8 months, a dural mass made its symptomatic and definite MR imaging appearance in the same region. No extracranial lesion was present.
Sunita D Nasta - One of the best experts on this subject based on the ideXlab platform.
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management and outcomes of sinus histiocytosis with massive lymphadenopathy rosai dorfman Disease
Leukemia & Lymphoma, 2020Co-Authors: Esin C Namoglu, Mitchell E Hughes, John P Plastaras, Daniel J Landsburg, Amit Maity, Sunita D NastaAbstract:AbstractSinus histiocytosis with massive lymphadenopathy (Rosai Dorfman Disease [RDD]), is a rare, benign but clinically heterogeneous histiocytic disorder. Our aims were to analyze the clinical ch...
