The Experts below are selected from a list of 318 Experts worldwide ranked by ideXlab platform
Dilek Angin - One of the best experts on this subject based on the ideXlab platform.
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Application of response surface methodology and artificial neural network on pyrolysis of Safflower Seed press cake
Energy Sources Part A: Recovery Utilization and Environmental Effects, 2016Co-Authors: Dilek Angin, Aysun Egrisogut TiryakiAbstract:ABSTRACTIn this study, mathematical correlation between the process variables and product yields for pyrolysis of Safflower Seed press cake (SPC) in fixed-bed reactor was investigated by using the response surface methodology (RSM) and artificial neural networks (ANNs). The RSM results showed that the second-order response model can be used to describe the relationship between the various factors and the response. Several feed-forward fully connected neural networks were investigated and optimal configuration of the ANN model was obtained. The results revealed that the ANN model could be considered as an alternative to RSM and practical modeling technique for the pyrolysis product yields.
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effect of pyrolysis temperature and heating rate on biochar obtained from pyrolysis of Safflower Seed press cake
Bioresource Technology, 2013Co-Authors: Dilek AnginAbstract:Abstract Biochar is carbon-rich product generated from biomass through pyrolysis. In this study, the effects of pyrolysis temperature and heating rate on the yield and physicochemical and morphological properties of biochars obtained from Safflower Seed press cake were investigated. The results showed that the biochar yield and quality depend principally on the applied temperature where pyrolysis at 600 °C leaves a biochar with higher fixed carbon content (80.70%) and percentage carbon (73.75%), and higher heating value (30.27 MJ kg−1) in comparison with the original feedstock (SPC) and low volatile matter content (9.80%). The biochars had low surface areas (1.89–4.23 m2/g) and contained predominantly aromatic compounds. The biochar could be used for the production of activated carbon, in fuel applications, and water purification processes.
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pyrolysis of Safflower charthamus tinctorius l Seed press cake in a fixed bed reactor part 2 structural characterization of pyrolysis bio oils
Bioresource Technology, 2008Co-Authors: Sevgi Sensoz, Dilek AnginAbstract:Abstract Biomass in the form of agricultural residues is becoming popular among new renewable energy sources, especially given its wide potential and abundant usage. Pyrolysis is the most important process among the thermal conversion processes of biomass. In this study, the various characteristics of bio-oils acquired under different pyrolysis conditions from Safflower Seed press cake (SPC) were identified. The elemental analyses and calorific values of the bio-oils were determined, and then the chemical compositions of the bio-oils were investigated using chromatographic and spectroscopic techniques such as column chromatography, 1 H NMR, FTIR and GC. The fuel properties of the bio-oil such as kinematic viscosity, flash point, density, water content and ASTM distillation were also determined. Chemical compositions of bio-oils showed that some quantities of hydrocarbons were present, while oxygenated and polar fractions dominated. The bio-oils obtained from Safflower Seed press cake were presented as an environmentally friendly feedstock candidate for biofuels and chemicals.
Jung-kiu Chai - One of the best experts on this subject based on the ideXlab platform.
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The effects of a bioabsorbable barrier membrane containing Safflower Seed extracts on periodontal healing of 1-wall intrabony defects in beagle dogs.
Journal of periodontology, 2005Co-Authors: Won‐seok Song, Gil-ja Jhon, Kyoo-sung Cho, Chong-kwan Kim, Seong-ho Choi, Chang-sung Kim, Hak Yong Kim, Jung-kiu ChaiAbstract:Background: Recently, there has been much research done into the regenerative potential of materials used in oriental medicine. In several studies, evidence was found that these materials have an effect on bone regeneration. Among these materials, Safflower Seeds are of particular interest as they have been used for the treatment of blood stasis, bone fracture, and osteoporosis in traditional Korean medicine. In addition, they are known to have anti-inflammatory effects. The objective of this study is to evaluate the periodontal tissue regenerative effects of a bioabsorbable barrier membrane (polylactide glycolic acid electro-spun non-woven membrane) containing Safflower Seed extracts applied to surgically created 1-wall intrabony defects in beagle dogs. Methods: One-wall intrabony defects were surgically created bilaterally at the mesial and distal sides of the mandibular second premolars and mesial side of the fourth premolars. These defects were randomly assigned either to the surgical control group wh...
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The effect of Safflower Seed extract on periodontal healing of 1-wall intrabony defects in beagle dogs.
Journal of periodontology, 2002Co-Authors: Hyun Young Kim, Gil-ja Jhon, Kyoo-sung Cho, Seong-ho Choi, Chang-sung Kim, Ik-sang Moon, Jung-kiu Chai, Chong-kwan KimAbstract:Background: Recent interest in naturally based products has increased. Various herbal extracts are known to have a variety of medicinal properties. Among the various natural medicines, Safflower Seeds have beneficial effects on various bone diseases such as bone fracture, osteoporosis, and osteodysplasia. In addition, they are known to have anti-inflammatory effects. The objective of this study was to evaluate the effect of a Safflower Seed extract (SSE) on the regeneration of periodontal tissue in a preclinical 1-wall model in dogs. Methods: Preclinical 1-wall periodontal defects were surgically created in the mesial aspect of the maxillary third and mandibular fourth premolar and in the distal aspect of the maxillary first and mandibular second premolar, and were randomly assigned to receive SSE/collagen (SSE/Col), phosphate-buffered saline/collagen (buffer control), or root planing only (surgical control). The created 1-wall defect configuration was 4 mm in depth by 4 mm in width. We selected the segme...
Eun Ju Cho - One of the best experts on this subject based on the ideXlab platform.
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Safflower carthamus tinctorius l Seed attenuates memory impairment induced by scopolamine in mice via regulation of cholinergic dysfunction and oxidative stress
Food & Function, 2019Co-Authors: Ji Hyun Kim, Yu Su Shin, Chan Hum Park, Min Jo Kim, Chang Yeol Yang, Takako Yokozawa, Eun Ju ChoAbstract:Cholinergic dysfunction and oxidative stress are the most common causes of Alzheimer's disease (AD). Safflower Seed contains various anti-oxidant and cholinergic improvement compounds, such as serotonin and its derivatives. In the present study, we investigated the protective effects and mechanisms of a Safflower Seed extract on scopolamine-induced memory impairment in a mouse model. The Safflower Seed extract was orally administered at a dose of 100 mg kg-1 day-1, and then behavior tests (such as T-maze and novel object recognition tests) were conducted. Acetyl cholinesterase (AChE) activity, reactive oxygen species (ROS) production, and antioxidant enzymes in the brain were measured. In behavior tests, the novel route exploration and object recognition were improved by the administration of the Safflower Seed extract, which suggests that the Safflower Seed extract improves memory function in the scopolamine-treated mouse model. In addition, the Safflower Seed extract-administered group showed inhibition of the AChE activity and improved cholinergic dysfunction. Furthermore, the administration of the Safflower Seed extract resulted in lower ROS production and higher antioxidant enzyme levels as compared to the scopolamine-treated group, suggesting the protective role of the Safflower Seed extract against oxidative stress. The results of the present study suggest that the Safflower Seed extract improves scopolamine-induced memory deficits via the inhibition of cholinergic dysfunction and oxidative stress. Therefore, Safflower Seeds might become a promising agent for memory improvement in AD patients.
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Protective Effect of Safflower Seed on Cisplatin-Induced Renal Damage in Mice via Oxidative Stress and Apoptosis-Mediated Pathways
The American journal of Chinese medicine, 2018Co-Authors: Chan Hum Park, Ah Young Lee, Ji Hyun Kim, Su Hui Seong, Gwi Yeong Jang, Eun Ju Cho, Jae Sue Choi, Jungkee Kwon, Young Ock Kim, Sang-won LeeAbstract:Cisplatin, a platinum chelate with potent antitumor activity against cancers of the testis, ovary, urinary bladder, prostate, and head and neck, has adverse effects on the kidney, bone marrow, and digestive organs, and its use is particularly limited by nephropathy as a side effect. In the present study, Safflower Seed extract was administered to a mouse model of cisplatin-induced acute renal failure to investigate its activity. Cisplatin (20[Formula: see text]mg/kg body weight) was administered by intraperitoneal injection to mice that had received oral Safflower Seed extract (100 or 200[Formula: see text]mg/kg body weight per day) for the preceding 2 days. Three days after the cisplatin injection, serum and renal biochemical factors; oxidative stress, inflammation, and apoptosis-related protein expression; and histological findings were evaluated. Cisplatin-treated control mice showed body-weight, food intake and water intake loss, and increased kidney weight, whereas the administration of Safflower Seed extract attenuated these effects ([Formula: see text], [Formula: see text]). Moreover, Safflower Seed extract significantly decreased the renal functional parameters urea nitrogen and creatinine in the serum ([Formula: see text] and [Formula: see text], respectively). Safflower Seed extract also significantly reduced the enhanced levels of reactive oxygen species in the kidney observed following cisplatin treatment, with significance. The expression of proteins related to the anti-oxidant defense system in the kidney was down-regulated following cisplatin treatment, but Safflower Seed extract significantly up-regulated the expression of the anti-oxidant enzyme catalase. Furthermore, Safflower Seed extract reduced the overexpression of phosphor (p)-p38, nuclear factor-kappa B p65, cyclooxygenase-2, inducible nitric oxide synthase, ATR, p-p53, Bax, and caspase 3 proteins, and mice treated with Safflower Seed extract exhibited less renal histological damage. These results provide important evidence that Safflower Seed extract exerts a pleiotropic effect on several oxidative stress- and apoptosis-related parameters and has a renoprotective effect in cisplatin-treated mice.
Chong-kwan Kim - One of the best experts on this subject based on the ideXlab platform.
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The effects of a bioabsorbable barrier membrane containing Safflower Seed extracts on periodontal healing of 1-wall intrabony defects in beagle dogs.
Journal of periodontology, 2005Co-Authors: Won‐seok Song, Gil-ja Jhon, Kyoo-sung Cho, Chong-kwan Kim, Seong-ho Choi, Chang-sung Kim, Hak Yong Kim, Jung-kiu ChaiAbstract:Background: Recently, there has been much research done into the regenerative potential of materials used in oriental medicine. In several studies, evidence was found that these materials have an effect on bone regeneration. Among these materials, Safflower Seeds are of particular interest as they have been used for the treatment of blood stasis, bone fracture, and osteoporosis in traditional Korean medicine. In addition, they are known to have anti-inflammatory effects. The objective of this study is to evaluate the periodontal tissue regenerative effects of a bioabsorbable barrier membrane (polylactide glycolic acid electro-spun non-woven membrane) containing Safflower Seed extracts applied to surgically created 1-wall intrabony defects in beagle dogs. Methods: One-wall intrabony defects were surgically created bilaterally at the mesial and distal sides of the mandibular second premolars and mesial side of the fourth premolars. These defects were randomly assigned either to the surgical control group wh...
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The effect of Safflower Seed extract on periodontal healing of 1-wall intrabony defects in beagle dogs.
Journal of periodontology, 2002Co-Authors: Hyun Young Kim, Gil-ja Jhon, Kyoo-sung Cho, Seong-ho Choi, Chang-sung Kim, Ik-sang Moon, Jung-kiu Chai, Chong-kwan KimAbstract:Background: Recent interest in naturally based products has increased. Various herbal extracts are known to have a variety of medicinal properties. Among the various natural medicines, Safflower Seeds have beneficial effects on various bone diseases such as bone fracture, osteoporosis, and osteodysplasia. In addition, they are known to have anti-inflammatory effects. The objective of this study was to evaluate the effect of a Safflower Seed extract (SSE) on the regeneration of periodontal tissue in a preclinical 1-wall model in dogs. Methods: Preclinical 1-wall periodontal defects were surgically created in the mesial aspect of the maxillary third and mandibular fourth premolar and in the distal aspect of the maxillary first and mandibular second premolar, and were randomly assigned to receive SSE/collagen (SSE/Col), phosphate-buffered saline/collagen (buffer control), or root planing only (surgical control). The created 1-wall defect configuration was 4 mm in depth by 4 mm in width. We selected the segme...
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The Effect of Safflower Seed Extract on the Bone Formation of Calvarial Bone Model in Sprague Dawley rat
The Journal of the Korean Academy of Periodontology, 2000Co-Authors: Sungtae Kim, Gil-ja Jhon, So-hyoung Lim, Kyoo-sung Cho, Chong-kwan Kim, Seong-ho ChoiAbstract:The ultimate goal of periodontal therapy is the regeneration of periodontal tissue and repair of function. For more than a decade there have been many efforts to develop materials and methods of treatment to promote periodontal wound healing. Recently many efforts are concentrated on the regeneration potential of material used in oriental medicine. In some in vitro and in vivo experiments, there have been many evidences that these materials have an effect on bone regeneration. The purpose of this study was to evaluate histologically and radiologically in Sprague-Dawley rats the effects of Safflower Seed extracts on the regeneration of the calvarial defects surgically produced. So in this study, the critical size defects were surgically produced in the calvarial bone of 30 Sprague-Dawley rats using the 8mm trephine bur. The Safflower Seed extract was applied into the defect of each rat in experimental group, whereas nothing was applied into the defect of each rat in control group. Rats were sacrificed at 2, 4, 8 weeks following operation and histomorphometric and radiodensitometric analysis were performed. The newly formed bone length was 102.91짹22.05, 178.29짹24.40 at 2 week in the each control, experimental group, 130.95짹39.24, 242.62짹50.33 at 4 week and 181.53짹76.35, 240.36짹22.00 at 8 week(unit, 쨉m). In the 2, 4 week, there were statistically significant difference between control and experimental group(P
Ozlem Yilmaz - One of the best experts on this subject based on the ideXlab platform.
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a shrinking core model and empirical kinetic approaches in supercritical co2 extraction of Safflower Seed oil
Journal of Supercritical Fluids, 2014Co-Authors: Nezihe Ayas, Ozlem YilmazAbstract:Abstract Utilization of supercritical CO 2 in Safflower Seed extraction was performed using a semi-batch extractor. Different extraction parameters, such as 40–60 MPa pressure, 323–347 K temperature, 20–76 min time, and 1–3 mL/min CO 2 flow rate were applied. A two-stage experimental design application was performed in order to maximize the oil yield. First of all, a 3 2 factorial design was applied to estimate the effect of the main factors and their interactions. The second part of the experimental design was improved and accelerated using the steepest ascent method. Optimum extraction parameters were determined to be 50 MPa pressure, 347 K temperature and 76 min time at a constant CO 2 flow rate (3 mL/min) according to the 2 2 design. Under these conditions, the oil yield obtained was 39.42%, comparable with Soxhlet extraction (40%) for 8 h. Shrinking core and empirical kinetic models were applied in order to generalize the extraction process. The predicted data was compatible with the experimental data.
