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Jae-suk Choi - One of the best experts on this subject based on the ideXlab platform.

  • in vivo antioxidant activity of mackerel Scomber japonicus muscle protein hydrolysate
    PeerJ, 2018
    Co-Authors: Khawaja Muhammad Imran Bashir, Jae Hak Sohn, Md. Mohibbullah, Ji-yeon Choi, Yong-ki Hong, Jin-soo Kim, Jae-suk Choi
    Abstract:

    Pacific chub mackerel (Scomber japonicus) is an important fish throughout the world, especially in East Asian countries, including Korea, China, and Japan. Protein hydrolysates from marine sources are commonly used as nutritional supplements, functional ingredients, and flavor enhancers in the food, beverage, and pharmaceutical industries. Antioxidants isolated from fish are relatively easy to prepare, are cost effective, and have no reported side effects. Hence, the present study aimed to investigate the in vivo antioxidant activities of mackerel muscle protein hydrolysate (MMPH) prepared using Protamex. The in vivo bioactivities of MMPH were investigated in alcoholic fatty liver mice (C57BL/6). Serum alanine aminotransferase and aspartate aminotransferase levels were comparable in test and control mice, whereas serum triglyceride and lipid peroxidation levels significantly (p < 0.05; p < 0.001) decreased after administration of MMPH (100-500 mg kg-1), especially at a concentration of 100 mg kg-1. A significant (p < 0.05) reduction in xanthine oxidase activity was observed in all groups treated with MMPH (100-500 mg kg-1), as compared with the control group. Significantly (p < 0.05) higher superoxide dismutase (SOD) activity/protein expression and regulated catalase (CAT) activity/protein expression levels were observed in groups administered MMPH (100-500 mg kg-1), especially at a concentration of 100 mg kg-1. These results show that the abundant amino acids of S. japonicus play an important role in the cytosol of the liver cells by directly participating in the expression of xanthine oxidase and the detoxifying SOD and CAT proteins, thereby enhancing antioxidant ability and ultimately, inhibiting lipid peroxidation. This study demonstrated that muscle protein hydrolysate from S. japonicus has strong antioxidant activities.

  • In vivo antioxidant activity of mackerel (Scomber japonicus) muscle protein hydrolysate
    PeerJ Inc., 2018
    Co-Authors: Khawaja Muhammad Imran Bashir, Jae Hak Sohn, Md. Mohibbullah, Ji-yeon Choi, Yong-ki Hong, Jin-soo Kim, Jae-suk Choi
    Abstract:

    Pacific chub mackerel (Scomber japonicus) is an important fish throughout the world, especially in East Asian countries, including Korea, China, and Japan. Protein hydrolysates from marine sources are commonly used as nutritional supplements, functional ingredients, and flavor enhancers in the food, beverage, and pharmaceutical industries. Antioxidants isolated from fish are relatively easy to prepare, are cost effective, and have no reported side effects. Hence, the present study aimed to investigate the in vivo antioxidant activities of mackerel muscle protein hydrolysate (MMPH) prepared using Protamex. The in vivo bioactivities of MMPH were investigated in alcoholic fatty liver mice (C57BL/6). Serum alanine aminotransferase and aspartate aminotransferase levels were comparable in test and control mice, whereas serum triglyceride and lipid peroxidation levels significantly (p 

  • Antioxidant Properties of Scomber japonicus Hydrolysates Prepared by Enzymatic Hydrolysis
    Journal of Aquatic Food Product Technology, 2017
    Co-Authors: Khawaja Muhammad Imran Bashir, Young-joo Park, Soo-jeong Choi, Jeong Hwan Kim, Man-kwon Baek, Andre Kim, Jae Hak Sohn, Jae-suk Choi
    Abstract:

    ABSTRACTThe antioxidant properties of the Pacific chub mackerel (Scomber japonicus) muscle protein hydrolysates prepared by enzymatic hydrolysis were investigated. After enzyme hydrolysis at 50°C f...

  • Antioxidant Properties of Scomber japonicus Hydrolysates Prepared by Enzymatic Hydrolysis
    2017
    Co-Authors: Khawaja Muhammad Imran Bashir, Young-joo Park, Soo-jeong Choi, Jeong Hwan Kim, Man-kwon Baek, Andre Kim, Jae Hak Sohn, Jae-suk Choi
    Abstract:

    The antioxidant properties of the Pacific chub mackerel (Scomber japonicus) muscle protein hydrolysates prepared by enzymatic hydrolysis were investigated. After enzyme hydrolysis at 50°C for 60 min, more than 80% of the S. japonicus muscle protein was hydrolyzed. The highest 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity (71.69%) occurred in whole muscle protein hydrolysates treated at 50°C for 30 min with Protamex, and the highest 2,2ʹ-azino-bis(3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) radical-scavenging activity (95.39%) was observed in white muscle protein hydrolysates treated at 50°C for 30 min with Neutrase. The highest superoxide dismutase (SOD)-like activity (32.84%) was recorded in white muscle protein hydrolysates treated at 50°C for 120 min with Protamex. Changes in the molecular weight distribution of S. japonicus muscle proteins after enzymatic hydrolysis were observed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). A robust and a convenient enzyme hydrolysis technique for obtaining S. japonicus muscle protein hydrolysates with useful biological activities, within a short time (

  • Physiological properties of Scomber japonicus meat hydrolysate prepared by subcritical water hydrolysis.
    Journal of environmental biology, 2016
    Co-Authors: Jae-suk Choi, Hye Eun Moon, Myong-kyun Roh, Bo-bae Lee, Kwang Keun Cho, In Soon Choi
    Abstract:

    The health-beneficial biological activities, including antioxidant and tyrosinase inhibitory activities, of Scomber japonicus muscle protein hydrolysates prepared by subcritical water hydrolysis were investigated. After 5 min of subcritical hydrolysis at 140 degrees C, 59.76% of S. japonicus muscle protein was hydrolyzed, the highest degree of hydrolysis in all the groups were tested. According to the response surface methodology results, as the reaction temperature and reaction time became lower and shorter, the yield became higher. The highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity (90.63%) occurred in hydrolysates treated at 140 degrees C for 5 min, and the highest tyrosinase inhibitory activity (65.54%) was identified in hydrolysates treated at 200 degreesC for 15 min. Changes in the molecular weight distribution of S. japonicus muscle proteins after subcritical water hydrolysis were observed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Subcritical water hydrolysis is a suitable technique for obtaining S.japonicus muscle protein hydrolysates with useful biological activities, within a short time (5-15 min).

Khawaja Muhammad Imran Bashir - One of the best experts on this subject based on the ideXlab platform.

  • in vivo antioxidant activity of mackerel Scomber japonicus muscle protein hydrolysate
    PeerJ, 2018
    Co-Authors: Khawaja Muhammad Imran Bashir, Jae Hak Sohn, Md. Mohibbullah, Ji-yeon Choi, Yong-ki Hong, Jin-soo Kim, Jae-suk Choi
    Abstract:

    Pacific chub mackerel (Scomber japonicus) is an important fish throughout the world, especially in East Asian countries, including Korea, China, and Japan. Protein hydrolysates from marine sources are commonly used as nutritional supplements, functional ingredients, and flavor enhancers in the food, beverage, and pharmaceutical industries. Antioxidants isolated from fish are relatively easy to prepare, are cost effective, and have no reported side effects. Hence, the present study aimed to investigate the in vivo antioxidant activities of mackerel muscle protein hydrolysate (MMPH) prepared using Protamex. The in vivo bioactivities of MMPH were investigated in alcoholic fatty liver mice (C57BL/6). Serum alanine aminotransferase and aspartate aminotransferase levels were comparable in test and control mice, whereas serum triglyceride and lipid peroxidation levels significantly (p < 0.05; p < 0.001) decreased after administration of MMPH (100-500 mg kg-1), especially at a concentration of 100 mg kg-1. A significant (p < 0.05) reduction in xanthine oxidase activity was observed in all groups treated with MMPH (100-500 mg kg-1), as compared with the control group. Significantly (p < 0.05) higher superoxide dismutase (SOD) activity/protein expression and regulated catalase (CAT) activity/protein expression levels were observed in groups administered MMPH (100-500 mg kg-1), especially at a concentration of 100 mg kg-1. These results show that the abundant amino acids of S. japonicus play an important role in the cytosol of the liver cells by directly participating in the expression of xanthine oxidase and the detoxifying SOD and CAT proteins, thereby enhancing antioxidant ability and ultimately, inhibiting lipid peroxidation. This study demonstrated that muscle protein hydrolysate from S. japonicus has strong antioxidant activities.

  • In vivo antioxidant activity of mackerel (Scomber japonicus) muscle protein hydrolysate
    PeerJ Inc., 2018
    Co-Authors: Khawaja Muhammad Imran Bashir, Jae Hak Sohn, Md. Mohibbullah, Ji-yeon Choi, Yong-ki Hong, Jin-soo Kim, Jae-suk Choi
    Abstract:

    Pacific chub mackerel (Scomber japonicus) is an important fish throughout the world, especially in East Asian countries, including Korea, China, and Japan. Protein hydrolysates from marine sources are commonly used as nutritional supplements, functional ingredients, and flavor enhancers in the food, beverage, and pharmaceutical industries. Antioxidants isolated from fish are relatively easy to prepare, are cost effective, and have no reported side effects. Hence, the present study aimed to investigate the in vivo antioxidant activities of mackerel muscle protein hydrolysate (MMPH) prepared using Protamex. The in vivo bioactivities of MMPH were investigated in alcoholic fatty liver mice (C57BL/6). Serum alanine aminotransferase and aspartate aminotransferase levels were comparable in test and control mice, whereas serum triglyceride and lipid peroxidation levels significantly (p 

  • Antioxidant Properties of Scomber japonicus Hydrolysates Prepared by Enzymatic Hydrolysis
    Journal of Aquatic Food Product Technology, 2017
    Co-Authors: Khawaja Muhammad Imran Bashir, Young-joo Park, Soo-jeong Choi, Jeong Hwan Kim, Man-kwon Baek, Andre Kim, Jae Hak Sohn, Jae-suk Choi
    Abstract:

    ABSTRACTThe antioxidant properties of the Pacific chub mackerel (Scomber japonicus) muscle protein hydrolysates prepared by enzymatic hydrolysis were investigated. After enzyme hydrolysis at 50°C f...

  • Antioxidant Properties of Scomber japonicus Hydrolysates Prepared by Enzymatic Hydrolysis
    2017
    Co-Authors: Khawaja Muhammad Imran Bashir, Young-joo Park, Soo-jeong Choi, Jeong Hwan Kim, Man-kwon Baek, Andre Kim, Jae Hak Sohn, Jae-suk Choi
    Abstract:

    The antioxidant properties of the Pacific chub mackerel (Scomber japonicus) muscle protein hydrolysates prepared by enzymatic hydrolysis were investigated. After enzyme hydrolysis at 50°C for 60 min, more than 80% of the S. japonicus muscle protein was hydrolyzed. The highest 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity (71.69%) occurred in whole muscle protein hydrolysates treated at 50°C for 30 min with Protamex, and the highest 2,2ʹ-azino-bis(3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) radical-scavenging activity (95.39%) was observed in white muscle protein hydrolysates treated at 50°C for 30 min with Neutrase. The highest superoxide dismutase (SOD)-like activity (32.84%) was recorded in white muscle protein hydrolysates treated at 50°C for 120 min with Protamex. Changes in the molecular weight distribution of S. japonicus muscle proteins after enzymatic hydrolysis were observed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). A robust and a convenient enzyme hydrolysis technique for obtaining S. japonicus muscle protein hydrolysates with useful biological activities, within a short time (

T. Kobayashi - One of the best experts on this subject based on the ideXlab platform.

Jae Hak Sohn - One of the best experts on this subject based on the ideXlab platform.

  • in vivo antioxidant activity of mackerel Scomber japonicus muscle protein hydrolysate
    PeerJ, 2018
    Co-Authors: Khawaja Muhammad Imran Bashir, Jae Hak Sohn, Md. Mohibbullah, Ji-yeon Choi, Yong-ki Hong, Jin-soo Kim, Jae-suk Choi
    Abstract:

    Pacific chub mackerel (Scomber japonicus) is an important fish throughout the world, especially in East Asian countries, including Korea, China, and Japan. Protein hydrolysates from marine sources are commonly used as nutritional supplements, functional ingredients, and flavor enhancers in the food, beverage, and pharmaceutical industries. Antioxidants isolated from fish are relatively easy to prepare, are cost effective, and have no reported side effects. Hence, the present study aimed to investigate the in vivo antioxidant activities of mackerel muscle protein hydrolysate (MMPH) prepared using Protamex. The in vivo bioactivities of MMPH were investigated in alcoholic fatty liver mice (C57BL/6). Serum alanine aminotransferase and aspartate aminotransferase levels were comparable in test and control mice, whereas serum triglyceride and lipid peroxidation levels significantly (p < 0.05; p < 0.001) decreased after administration of MMPH (100-500 mg kg-1), especially at a concentration of 100 mg kg-1. A significant (p < 0.05) reduction in xanthine oxidase activity was observed in all groups treated with MMPH (100-500 mg kg-1), as compared with the control group. Significantly (p < 0.05) higher superoxide dismutase (SOD) activity/protein expression and regulated catalase (CAT) activity/protein expression levels were observed in groups administered MMPH (100-500 mg kg-1), especially at a concentration of 100 mg kg-1. These results show that the abundant amino acids of S. japonicus play an important role in the cytosol of the liver cells by directly participating in the expression of xanthine oxidase and the detoxifying SOD and CAT proteins, thereby enhancing antioxidant ability and ultimately, inhibiting lipid peroxidation. This study demonstrated that muscle protein hydrolysate from S. japonicus has strong antioxidant activities.

  • In vivo antioxidant activity of mackerel (Scomber japonicus) muscle protein hydrolysate
    PeerJ Inc., 2018
    Co-Authors: Khawaja Muhammad Imran Bashir, Jae Hak Sohn, Md. Mohibbullah, Ji-yeon Choi, Yong-ki Hong, Jin-soo Kim, Jae-suk Choi
    Abstract:

    Pacific chub mackerel (Scomber japonicus) is an important fish throughout the world, especially in East Asian countries, including Korea, China, and Japan. Protein hydrolysates from marine sources are commonly used as nutritional supplements, functional ingredients, and flavor enhancers in the food, beverage, and pharmaceutical industries. Antioxidants isolated from fish are relatively easy to prepare, are cost effective, and have no reported side effects. Hence, the present study aimed to investigate the in vivo antioxidant activities of mackerel muscle protein hydrolysate (MMPH) prepared using Protamex. The in vivo bioactivities of MMPH were investigated in alcoholic fatty liver mice (C57BL/6). Serum alanine aminotransferase and aspartate aminotransferase levels were comparable in test and control mice, whereas serum triglyceride and lipid peroxidation levels significantly (p 

  • Antioxidant Properties of Scomber japonicus Hydrolysates Prepared by Enzymatic Hydrolysis
    Journal of Aquatic Food Product Technology, 2017
    Co-Authors: Khawaja Muhammad Imran Bashir, Young-joo Park, Soo-jeong Choi, Jeong Hwan Kim, Man-kwon Baek, Andre Kim, Jae Hak Sohn, Jae-suk Choi
    Abstract:

    ABSTRACTThe antioxidant properties of the Pacific chub mackerel (Scomber japonicus) muscle protein hydrolysates prepared by enzymatic hydrolysis were investigated. After enzyme hydrolysis at 50°C f...

  • Antioxidant Properties of Scomber japonicus Hydrolysates Prepared by Enzymatic Hydrolysis
    2017
    Co-Authors: Khawaja Muhammad Imran Bashir, Young-joo Park, Soo-jeong Choi, Jeong Hwan Kim, Man-kwon Baek, Andre Kim, Jae Hak Sohn, Jae-suk Choi
    Abstract:

    The antioxidant properties of the Pacific chub mackerel (Scomber japonicus) muscle protein hydrolysates prepared by enzymatic hydrolysis were investigated. After enzyme hydrolysis at 50°C for 60 min, more than 80% of the S. japonicus muscle protein was hydrolyzed. The highest 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity (71.69%) occurred in whole muscle protein hydrolysates treated at 50°C for 30 min with Protamex, and the highest 2,2ʹ-azino-bis(3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) radical-scavenging activity (95.39%) was observed in white muscle protein hydrolysates treated at 50°C for 30 min with Neutrase. The highest superoxide dismutase (SOD)-like activity (32.84%) was recorded in white muscle protein hydrolysates treated at 50°C for 120 min with Protamex. Changes in the molecular weight distribution of S. japonicus muscle proteins after enzymatic hydrolysis were observed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). A robust and a convenient enzyme hydrolysis technique for obtaining S. japonicus muscle protein hydrolysates with useful biological activities, within a short time (

Leonardo S Tringali - One of the best experts on this subject based on the ideXlab platform.