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Volkan Yeter - One of the best experts on this subject based on the ideXlab platform.
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changes in corneal thickness upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment anterior segment optical coherence tomography study
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal EserozturkAbstract:PURPOSE: To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). METHODS: The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. RESULTS: Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm2 and 0.017 ± 0.007 mm2, respectively, and they were 0.017 ± 0.009 mm2 and 0.016 ± 0.007 mm2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score (p < 0.05). CONCLUSION: There is no change in corneal epithelial thickness and upper tear meniscus area after 1-week treatment with loteprednol etabonate in patients with Seasonal Allergic Conjunctivitis, but it may cause decrease in non-epithelial corneal thickness and lower tear meniscus area.
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Changes in corneal thickness, upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment: anterior segment optical coherence tomography study
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal Eser-ozturkAbstract:Purpose To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). Methods The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. Results Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm^2 and 0.017 ± 0.007 mm^2, respectively, and they were 0.017 ± 0.009 mm^2 and 0.016 ± 0.007 mm^2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score ( p
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Changes in corneal thickness, upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment: anterior segment optical coherence tomography study.
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal Eser-ozturkAbstract:PURPOSE: To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). METHODS: The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. RESULTS: Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm2 and 0.017 ± 0.007 mm2, respectively, and they were 0.017 ± 0.009 mm2 and 0.016 ± 0.007 mm2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score (p
Hilal Eser-ozturk - One of the best experts on this subject based on the ideXlab platform.
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Changes in corneal thickness, upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment: anterior segment optical coherence tomography study
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal Eser-ozturkAbstract:Purpose To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). Methods The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. Results Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm^2 and 0.017 ± 0.007 mm^2, respectively, and they were 0.017 ± 0.009 mm^2 and 0.016 ± 0.007 mm^2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score ( p
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Changes in corneal thickness, upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment: anterior segment optical coherence tomography study.
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal Eser-ozturkAbstract:PURPOSE: To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). METHODS: The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. RESULTS: Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm2 and 0.017 ± 0.007 mm2, respectively, and they were 0.017 ± 0.009 mm2 and 0.016 ± 0.007 mm2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score (p
Nurullah Kocak - One of the best experts on this subject based on the ideXlab platform.
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changes in corneal thickness upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment anterior segment optical coherence tomography study
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal EserozturkAbstract:PURPOSE: To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). METHODS: The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. RESULTS: Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm2 and 0.017 ± 0.007 mm2, respectively, and they were 0.017 ± 0.009 mm2 and 0.016 ± 0.007 mm2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score (p < 0.05). CONCLUSION: There is no change in corneal epithelial thickness and upper tear meniscus area after 1-week treatment with loteprednol etabonate in patients with Seasonal Allergic Conjunctivitis, but it may cause decrease in non-epithelial corneal thickness and lower tear meniscus area.
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Changes in corneal thickness, upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment: anterior segment optical coherence tomography study
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal Eser-ozturkAbstract:Purpose To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). Methods The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. Results Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm^2 and 0.017 ± 0.007 mm^2, respectively, and they were 0.017 ± 0.009 mm^2 and 0.016 ± 0.007 mm^2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score ( p
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Changes in corneal thickness, upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment: anterior segment optical coherence tomography study.
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal Eser-ozturkAbstract:PURPOSE: To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). METHODS: The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. RESULTS: Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm2 and 0.017 ± 0.007 mm2, respectively, and they were 0.017 ± 0.009 mm2 and 0.016 ± 0.007 mm2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score (p
Hilal Eserozturk - One of the best experts on this subject based on the ideXlab platform.
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changes in corneal thickness upper and lower tear film in Seasonal Allergic Conjunctivitis by steroid treatment anterior segment optical coherence tomography study
International Ophthalmology, 2020Co-Authors: Volkan Yeter, Nurullah Kocak, Hilal EserozturkAbstract:PURPOSE: To evaluate the effects of loteprednol etabonate on cornea and tear film in patients with Seasonal Allergic Conjunctivitis by anterior segment optical coherence tomography (OCT). METHODS: The right eyes of 52 subjects with Seasonal Allergic Conjunctivitis were evaluated in the study. Central corneal thickness (CCT), the thicknesses of central corneal epithelium (CET) and central non-epithelial cornea (CnET), and lower and upper tear meniscus areas were measured by spectral-domain OCT and ocular surface disease index (OSDI) were obtained at baseline. After topical use of loteprednol etabonate 0.5% eye drop three times a day for 1 week, the measurements were repeated. Paired T test was used for analysis. RESULTS: Mean CCT and mean thicknesses of CET and CnET at baseline were 528.19 ± 34.47 µm, 64.10 ± 5.30 µm and 462.84 ± 33.43 µm, respectively, and these were 526.31 ± 33.37 µm, 64.65 ± 4.84 µm and 459.84 ± 32.11 µm after the treatment, respectively. OSDI score was 21.55 ± 4.40 at baseline and 13.13 ± 2.39 after 1 week. The lower and upper tear meniscus areas at baseline were 0.026 ± 0.017 mm2 and 0.017 ± 0.007 mm2, respectively, and they were 0.017 ± 0.009 mm2 and 0.016 ± 0.007 mm2, respectively, after the treatment. There is statistically significant difference between before and after values of CCT, CnET, lower tear meniscus area and OSDI score (p < 0.05). CONCLUSION: There is no change in corneal epithelial thickness and upper tear meniscus area after 1-week treatment with loteprednol etabonate in patients with Seasonal Allergic Conjunctivitis, but it may cause decrease in non-epithelial corneal thickness and lower tear meniscus area.
Markku Leino - One of the best experts on this subject based on the ideXlab platform.
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Studies comparing the efficacy of nedocromil sodium eye drops with sodium cromoglycate and placebo in Seasonal Allergic Conjunctivitis
Ocular Immunology and Inflammation, 2009Co-Authors: Markku LeinoAbstract:Two multicentre, double-blind, placebo controlled group comparative studies were carried out in Finland, during the birch pollen seasons of 1987 and 1989, to compare the efficacy and tolerability of 2% nedocromil sodium eye drops (twice daily) with either 2% sodium cromoglycate eye drops (four times daily) and/or placebo, in patients with Seasonal Allergic Conjunctivitis. Study 1 compared nedocromil sodium (64 patients) with placebo (62 patients) and showed that the opinions of treatment efficacy of both patients and clinicians were significantly in favour of nedocromil sodium (p = 0.003, patients; p = 0.006, clinicians). In addition, the placebo group used significantly more topical (p
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the effect of sodium cromoglycate eyedrops compared to the effect of terfenadine on acute symptoms of Seasonal Allergic Conjunctivitis
Acta Ophthalmologica, 2009Co-Authors: Markku Leino, Christer Carlson, Olavi Kilkku, Tuula Kumpulainen, Sinikka Kyronpalokauppinen, Ville Laaka, Matti Norio, Jorma ValtolaAbstract:. A multicentre, group comparative open study was carried out on 68 patients to compare the effects of 2% sodium cromoglycate eyedrops and an oral antihistamine, terfenadine, on acute symptoms of Seasonal Allergic Conjunctivitis. The study was continued for one week after the onset of acute symptoms. Both medications were equally efficient in reducing symptoms during the first hour of observation. During the one-week follow-up both medications reduced symptoms to a low level, and both medications were equally effective for Allergic symptoms, except that terfenadine was more effective in reducing the watering of eyes.
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studies comparing the efficacy of nedocromil sodium eye drops with sodium cromoglycate and placebo in Seasonal Allergic Conjunctivitis
Ocular Immunology and Inflammation, 1993Co-Authors: Markku LeinoAbstract:Two multicentre, double-blind, placebo controlled group comparative studies were carried out in Finland, during the birch pollen seasons of 1987 and 1989, to compare the efficacy and tolerability of 2% nedocromil sodium eye drops (twice daily) with either 2% sodium cromoglycate eye drops (four times daily) and/or placebo, in patients with Seasonal Allergic Conjunctivitis. Study 1 compared nedocromil sodium (64 patients) with placebo (62 patients) and showed that the opinions of treatment efficacy of both patients and clinicians were significantly in favour of nedocromil sodium (p = 0.003, patients; p = 0.006, clinicians). In addition, the placebo group used significantly more topical (p<0.05) and oral (p<0.01) concomitant antihistamine therapy. Diary card scores and clinical assessments showed trends for active treatment. Study 2 compared nedocromil sodium (60 patients) with sodium cromoglycate (61) and placebo (64). Symptomatology was low, in general, but patient diary card scores showed significant cont...
