The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Sang Woong Youn - One of the best experts on this subject based on the ideXlab platform.
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Relation between pH in the Trunk and Face: Truncal pH Can Be Easily Predicted from Facial pH.
Annals of Dermatology, 2016Co-Authors: Sung Ae Kim, Mi Young Chun, Bo Ri Kim, Sang Woong YounAbstract:Background: The clinical symptoms of facial and truncal acne differ. Skin surface acidity (pH), which is affected by Sebum secretions, reflects the different clinical characteristics of the face and trunk. However, no studies have been conducted on truncal Sebum production and skin pH. Objective: We evaluated the differences and relationship between pH values of the face and trunk. We also evaluated the relationship between pH and the quantity of Sebum produced in the trunk. Methods: A total of 35 female patients clinically diagnosed with truncal acne were included. We measured pH on the face and truncal area using the Skin-pH-Meter PH 905 Ⓡ . We measured truncal Sebum secretions using the Sebumeter SM 815 Ⓡ . Statistical analysis was performed to evaluate the correlations and differences between pH and Sebum. Results: Facial pH was significantly higher than chest and back pH values. The correlation between pH on the trunk and the face was significant. We used linear regression equations to estimate truncal pH using only measured pH from the chin. There was no significant relationship between truncal Sebum secretion and pH. Conclusion: This was the first study that evaluated the differences and correlations between facial and truncal pH. We found that facial pH can predict truncal pH. In addition, we conclude that differences in pH and Sebum secretion between the face and trunk are one of the reasons for differences in acne symptom at those sites. (Ann Dermatol 28(2) 216∼221, 2016)
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Sebum Secretion of the Trunk and the Development of Truncal Acne in Women: Do Truncal Acne and Sebum Affect Each Other?
Dermatology, 2015Co-Authors: Bo Ri Kim, Mi Young Chun, Sung Ae Kim, Sang Woong YounAbstract:Background: There are few published data on truncal acne because most studies have focused on facial acne. Aims: The objective of this study was to investigate truncal Sebum secretion levels in patients with acne vulgaris and to evaluate the relationship between Sebum secretion and the development of acne lesions. Methods: The Sebum casual levels at five different facial sites and ten truncal sites were measured in 35 Korean females with acne using a Sebumeter®. We performed an analysis of the correlation between Sebum excretion and acne lesion number. Results: We found that all of the truncal sites analyzed had lower Sebum secretion levels than the facial sites. There was no significant correlation between Sebum secretion and acne lesions on the trunk. Conclusion: Pathogenic factors other than Sebum may have a predominant role in the development of truncal acne.
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Sebum Secretion, Skin Type, and pH
Pathogenesis and Treatment of Acne and Rosacea, 2014Co-Authors: Sang Woong YounAbstract:Increased facial Sebum secretion is a common finding during the period when acne commonly develops. Patients with acne frequently think that facial Sebum is the cause of their disease and want to lower or remove it completely. Sebum is always listed as one of the important factors involved in the pathogenesis of acne. Quantitative measurement of Sebum has only recently become possible; currently, we have limited information on the secretion of Sebum itself. The cosmetic skin type is another common method of assessing facial Sebum secretion and the skin surface pH (SSPH) is partially affected by facial Sebum secretion. In this chapter, Sebum secretion, facial skin type, and SSPH will be reviewed with regard to their prognostic significance for acne.
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Subjective facial skin type, based on the Sebum related symptoms, can reflect the objective casual Sebum level in acne patients
Skin Research and Technology, 2012Co-Authors: C. W. Choi, Jae Woo Choi, Sang Woong YounAbstract:Background The relationship between the subjective skin type and the casual Sebum level was not fully clarified. Objectives To investigate the characteristics of subjective skin type and to find the relationship between the subjective skin types and the skin type-related symptoms, casual Sebum level, along with the objective skin type. Methods Seven hundred and nine patients, clinically diagnosed with acne, were included. The questionnaire and the casual Sebum level measurement were performed. The determining symptoms of each subjective skin type were investigated. The 95% confidence interval of casual Sebum level of each subjective skin type was calculated. Results The most frequent subjective skin type was the combination type. The dryness, tightness, and oiliness can be conclusive symptoms in determining the subjective skin type. The mean and the 95% confidence interval of the casual Sebum level was highest in the oily skin type, followed by the combination, normal, and dry skin type. Conclusion We found that the subjective skin type was determined by the skin type-related symptoms. The 95% confidence intervals of the casual Sebum level of each subjective skin type were established. Based on the skin type-related symptoms, the casual Sebum level of acne patients can be estimated.
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Facial Sebum affects the development of acne, especially the distribution of inflammatory acne
Journal of The European Academy of Dermatology and Venereology, 2011Co-Authors: C. W. Choi, K.c. Park, Jung Won Choi, Sang Woong YounAbstract:Background The increased Sebum secretion has been considered as one of the pathogenic factors of acne. Objective The goal of this study was to assess the correlation between the casual Sebum level and the severity of acne using objective measuring methods in a large acne patients group. We also investigated the influence of age or gender on the correlation. Methods A total number of 914 acne patients were recruited. The standard digital photographs were taken, and the acne lesions were counted as comedones or inflammatory lesions. The casual Sebum level was measured using the Sebumeter SM 815 � . The correlation analysis was performed. Results The casual Sebum level showed positive correlation with the number of acne lesions. The casual Sebum level markedly influenced the number of inflammatory lesions and the acne lesions located in the U-zone. In the young acne patients, the casual Sebum level showed significant correlations in the U-zone, whereas in the old acne patients, there were significant correlations in the T-zone. The male acne patients were more influenced by the casual Sebum level. Conclusion This was the first study to report the significant correlations between the casual Sebum level and the number, proportion and location of acne lesions in a large acne patients group, using an objective, bioengineering method. Moreover, we also found that the influence of Sebum was prominent on the inflammatory lesions. In addition, both age and gender influenced the correlation between the casual Sebum level and the acne.
Marta C. Yappert - One of the best experts on this subject based on the ideXlab platform.
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Sebum/Meibum Surface Film Interactions and Phase Transitional Differences.
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
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Sebum meibum surface film interactions and phase transitional differences
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
Poonam Mudgil - One of the best experts on this subject based on the ideXlab platform.
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Sebum/Meibum Surface Film Interactions and Phase Transitional Differences.
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
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Sebum meibum surface film interactions and phase transitional differences
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
Dylan Gerlach - One of the best experts on this subject based on the ideXlab platform.
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Sebum/Meibum Surface Film Interactions and Phase Transitional Differences.
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
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Sebum meibum surface film interactions and phase transitional differences
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
Douglas Borchman - One of the best experts on this subject based on the ideXlab platform.
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Sebum/Meibum Surface Film Interactions and Phase Transitional Differences.
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
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Sebum meibum surface film interactions and phase transitional differences
Investigative Ophthalmology & Visual Science, 2016Co-Authors: Poonam Mudgil, Douglas Borchman, Dylan Gerlach, Marta C. YappertAbstract:PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if Sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of Sebum is due to squalene (SQ); and if Sebum or SQ, a major component of Sebum, interacts with human meibum. METHODS Human meibum was collected from the lid margin with a platinum spatula. Human Sebum was collected using lipid absorbent tape. Langmuir trough technology was used to measure the rheology of surface films. Infrared spectroscopy was used to measure lipid conformation and phase transitions. We used 1H-NMR to measure composition and confirm the primary structure of SQ. RESULTS The NMR resonance near 5.2 ppm in the spectra of human Sebum was from SQ which composed 28 mole percent of Sebum. Both Sebum and SQ lowered the lipid order of meibum. Sebum expanded meibum films at lower concentrations and condensed meibum films at higher concentrations. Sebum caused meibum to be more stable at higher pressures (greater maximum surface pressure). CONCLUSIONS Physiological levels of Sebum would be expected to expand or fluidize meibum making it spread better and be more surface active (qualities beneficial for tear film stability). Sebum would also be expected to stabilize the tear film lipid layer, which may allow it to withstand the high shear pressure of a blink.
